Journal of Korean Endocrine Society 1999;14(1):171-176.
Published online January 1, 2001.
A Case of Parathyroid Carcinoma Invading Thyroid Gland as Solitary Nodular Form.
Young Keun Choi, Jae Seung Lee, Hyung Wook Kim, Young Min Kim, Seok Man Son, In Joo Kim, Yong Ki Kim, Hyo Jung Chae
1Department of Internal Medicine, Pusan National University College of Medicine, Pusan, Korea.
2Department of Anatomical Pathology, Pusan National University College of Medicine, Pusan, Korea.
Abstract
Parathyroid carcinoma is a rare cause of primary hyperparathyroidism and commonly metastasize to lymph node, lung, liver, and bone. In Korea, there has been no report of distant metastasis in parathyroid carcinoma except for one case of pulmonary metastasis. A 58-year-old man presenting with weakness, nausea, and a palpable thyroid nodule visited our hospital. Elevated serum calcium and parathyroid hormone (PTH) concentration allowed the diagnosis of hyperparathyroidism. Two discrete masses were identified by neck ultrasound scan, computed tomography (CI') and Tc-Sestamibi scan in the left lobe of thyroid gland and ipsilateral parathyroid gland. So multiple endocrine neoplasia (MEN) type 2A" was suspected initially, but postoperative histological diagnosis was left parathyroid carcinoma with solitary nodular lesion invading left thyroid gland. He was successfully treated with left parathyroidectomy and left thyroid lobectomy.
Key Words: Parathyroid carcinoma, Solitary nodular lesion, Thyroid gland, MEN 2A


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