Endocrinology and Metabolism

Review Article

Diabetes, Obesity and Metabolism Big Data Articles (National Health Insurance Service Database)
Big Data Research in the Field of Endocrine Diseases Using the Korean National Health Information Database: Sun Wook Cho, Jung Hee Kim, Han Seok Choi, Hwa Young Ahn, Mee Kyoung Kim, Eun Jung Rhee; Endocrinol Metab. 2023;38(1):10-24. Published online February 9, 2023; DOI: https://doi.org/10.3803/EnM.2023.102

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The Korean National Health Information Database (NHID) contains big data combining information obtained from the National Health Insurance Service and health examinations. Data are provided in the form of a cohort, and the NHID can be used to conduct longitudinal studies and research on rare diseases. Moreover, data on the cause and date of death are provided by Statistics Korea. Research and publications based on the NHID have increased explosively in the field of endocrine disorders. However, because the data were not collected for research purposes, studies using the NHID have limitations, particularly the need for the operational definition of diseases. In this review, we describe the characteristics of the Korean NHID, operational definitions of endocrine diseases used for research, and an overview of recent studies in endocrinology using the Korean NHID.

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Special Article

Miscellaneous
Immune Checkpoint Inhibitors and Endocrine Disorders: A Position Statement from the Korean Endocrine Society: Hyemi Kwon, Eun Roh, Chang Ho Ahn, Hee Kyung Kim, Cheol Ryong Ku, Kyong Yeun Jung, Ju Hee Lee, Eun Heui Kim, Sunghwan Suh, Sangmo Hong, Jeonghoon Ha, Jun Sung Moon, Jin Hwa Kim, Mi-kyung Kim, The Committee of Clinical Practice Guideline of the Korean Endocrine Society; Endocrinol Metab. 2022;37(6):839-850. Published online December 26, 2022; DOI: https://doi.org/10.3803/EnM.2022.1627

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Immune checkpoint inhibitors (ICIs) including an anti-cytotoxic T-lymphocyte-associated antigen 4 inhibitor, anti-programmed cell death protein 1 (PD-1) inhibitors, and anti-PD-ligand 1 inhibitors are representative therapeutics for various malignancies. In oncology, the application of ICIs is currently expanding to a wider range of malignancies due to their remarkable clinical outcomes. ICIs target immune checkpoints which suppress the activity of T-cells that are specific for tumor antigens, thereby allowing tumor cells to escape the immune response. However, immune checkpoints also play a crucial role in preventing autoimmune reactions. Therefore, ICIs targeting immune checkpoints can trigger various immune-related adverse events (irAEs), especially in endocrine organs. Considering the endocrine organs that are frequently involved, irAEs associated endocrinopathies are frequently life-threatening and have unfavorable clinical implications for patients. However, there are very limited data from large clinical trials that would inform the development of clinical guidelines for patients with irAEs associated endocrinopathies. Considering the current clinical situation, in which the scope and scale of the application of ICIs are increasing, position statements from clinical specialists play an essential role in providing the appropriate recommendations based on both medical evidence and clinical experience. As endocrinologists, we would like to present precautions and recommendations for the management of immune-related endocrine disorders, especially those involving the adrenal, thyroid, and pituitary glands caused by ICIs.

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Review Articles

Miscellaneous
Encountering COVID-19 as Endocrinologists: Eun-Jung Rhee, Jung Hee Kim, Sun Joon Moon, Won-Young Lee; Endocrinol Metab. 2020;35(2):197-205. Published online June 23, 2020; DOI: https://doi.org/10.3803/EnM.2020.35.2.197

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The world is entering an era of disaster and chaos due to coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2. Since its first emergence in December 2019 in Wuhan, China, COVID-19 has swept through Asia and propagated throughout the world to Europe and North America. As of April 13, 1,773,084 people were infected and 111,652 people had died from COVID-19 globally, and new record levels of infection are being reported every day. Based on the data that have been amassed so far, the primary risk factors for a severe disease course or even mortality from COVID-19 are underlying diseases such as diabetes and hypertension. As the global prevalence of diabetes continues to increase, patients with endocrine diseases such as diabetes mellitus and those who are on long-term corticosteroid therapy due to adrenal insufficiency or hypopituitarism are at risk for a poor prognosis of COVID-19. As endocrinologists, we would like to briefly review the current knowledge about the relationship between COVID-19 and endocrine diseases and to discuss what we can do for the safety and health of our patients with endocrine diseases in this globally threatening situation.

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Miscellaneous
Human Immunodeficiency Virus Infection and the Endocrine System: Dana Zaid, Yona Greenman; Endocrinol Metab. 2019;34(2):95-105. Published online May 20, 2019; DOI: https://doi.org/10.3803/EnM.2019.34.2.95

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In the current era of effective antiretroviral therapies (ARTs), human immunodeficiency virus (HIV) infection became a chronic disorder that requires long term follow-up. Among other medical issues, these patients may develop endocrine problems, specific to HIV infection and its treatment. The purpose of this review is to give an overview of common endocrine complications associated with HIV infection, and to propose diagnostic and therapeutic strategies. HIV can affect the endocrine system at several levels. Adrenal and gonadal dysfunction, osteoporosis with increased fracture risk, dyslipidemia with increased cardiovascular risk, are some of the endocrine disorders prevalent in HIV-infected patients that may negatively influence quality of life, and increase morbidity and mortality. While ARTs have dramatically increased life expectancy in the HIV-infected population, they are not devoid of adverse effects, including endocrine dysfunction. Physicians caring for HIV-infected patients should be knowledgeable and exercise a high index of suspicion for the diagnosis of endocrine abnormalities, and in particular be aware of those that can be life threatening. Endocrine evaluation should follow the same strategies as in the general population, including prevention, early detection, and treatment.

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Journal of Diabetes and Endocrinology.2023; 13(1): 1. CrossRef
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BMC Infectious Diseases.2023;[Epub] CrossRef
Allopregnanolone and neuroHIV: Potential benefits of neuroendocrine modulation in the era of antiretroviral therapy
Mohammed F. Salahuddin, Alaa N. Qrareya, Fakhri Mahdi, Emaya Moss, Nicholas S. Akins, Jing Li, Hoang V. Le, Jason J. Paris
Journal of Neuroendocrinology.2022;[Epub] CrossRef
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The Journal for Nurse Practitioners.2022; 18(5): 525. CrossRef
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Molecular and Cellular Biochemistry.2022; 477(5): 1381. CrossRef
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Felipe P. Oliveira, Luis F. C. Lima, Francisco de Paula Paranhos Neto, Laura M. C. de Mendonça, Annie Schtscherbyna, Luiz A. A. de Lima, Branca A. Fonseca, Miguel Madeira, Ronir R. Luiz, Leonardo V. Neto, Maria L. F. Farias, Elizabeth S. Machado
Clinical Endocrinology.2022; 97(1): 142. CrossRef
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Andrologia.2022;[Epub] CrossRef
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Opeyemi M. Folorunso, Chiara Frazzoli, Ifeyinwa Chijioke-Nwauche, Beatrice Bocca, Orish E. Orisakwe
Medicina.2021; 57(5): 492. CrossRef
Propensity score matching evaluation of psychological stress and hair cortisol among people living with HIV in China
Xu Chen, Shuaifeng Liu, Chengbo Zeng, Xiaoming Li, Shan Qiao, Riying Lv, Zhiyong Shen
Scientific Reports.2021;[Epub] CrossRef
Adrenal insufficiency in HIV/AIDS: a review
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Expert Review of Endocrinology & Metabolism.2021; 16(6): 351. CrossRef
REPRODUCTIVE DISORDERS AND THEIR PATHOGENETIC MECHANISMS IN WOMEN WITH HIV
O. Ya. Leshchenko, E. V. Genich
HIV Infection and Immunosuppressive Disorders.2020; 11(4): 20. CrossRef
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Alessandra Iacovelli, Ivano Mezzaroma, Marcello Di Paolo, Giuseppe Soda, Ludovica De Vincentiis, Paolo Palange
BMC Infectious Diseases.2020;[Epub] CrossRef
Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents
Edoardo Spina, Maria Antonietta Barbieri, Giuseppe Cicala, Jose de Leon
Pharmaceuticals.2020; 13(12): 439. CrossRef

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