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2 "Osteonecrosis"
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Review Article
Calcium & Bone Metabolism
Review and Update of the Risk Factors and Prevention of Antiresorptive-Related Osteonecrosis of the Jaw
Ha Young Kim
Endocrinol Metab. 2021;36(5):917-927.   Published online October 21, 2021
DOI: https://doi.org/10.3803/EnM.2021.1170
  • 4,500 View
  • 269 Download
  • 9 Web of Science
  • 11 Crossref
AbstractAbstract PDFPubReader   ePub   
Antiresorptive-related osteonecrosis of the jaw (ARONJ) is a rare but serious adverse event of bisphosphonate or denosumab administration; it is associated with severe pain and a deteriorated quality of life. Since its first report in 2003, there have been many studies on its definition, epidemiology, pathophysiology, diagnosis, and treatment. Nevertheless, the epidemiology and mechanisms underlying this condition have not yet been fully delineated and several risk factors are known. Moreover, as there is no effective treatment currently available for osteonecrosis of the jaw, prevention is essential. Furthermore, close cooperation between prescribing physicians and dentists is important. The aim of this review was to provide up-to-date information regarding the risk factors and prevention of ARONJ from a physician’s perspective.

Citations

Citations to this article as recorded by  
  • Risk factors for dental findings of the development of medication-related osteonecrosis of the jaw: Investigation of 3734 teeth in cancer patients receiving high dose antiresorptive agents
    Mitsunobu Otsuru, Yoshinari Fujiki, Sakiko Soutome, Norio Nakamura, Taro Miyoshi, Tomofumi Naruse, Mizuho Ohnuma, Yuka Hotokezaka, Satoshi Rokutanda, Masahiro Umeda
    Journal of Dental Sciences.2024; 19(1): 203.     CrossRef
  • Editorial: Immunological processes in maxillofacial bone pathology
    Matthias Tröltzsch
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • Polysacharide of Agaricus blazei gel mitigates bone necrosis in model of the jaws related to bisphosphonate via Wnt signaling
    Vanessa Costa de Sousa, Fátima Regina Nunes Sousa, Raquel Felipe Vasconcelos, Gisele Angelino Barreto, Conceição S. Martins, Nilson Romero Dias, Sislana Costa, Maria Jennifer Chaves Bernardino, George de Almeida Silva, Nadine Linhares, Delane Gondim, Mirn
    Scientific Reports.2024;[Epub]     CrossRef
  • Prevention of medication-related osteonecrosis of the jaw after tooth extraction by local administration of antibiotics and atelocollagen sponge: A preliminary study
    Natsumi Nakamura, Sakiko Soutome, Akira Imakiire, Satoshi Rokutanda, Seigo Ohba, Shunsuke Sawada, Yuka Kojima, Yuki Sakamoto, Yoshiko Yamamura, Madoka Funahara, Mitsunobu Otsuru, Masahiro Umeda
    Journal of Dental Sciences.2024;[Epub]     CrossRef
  • When and how to stop denosumab therapy in a patient with osteoporosis
    Eirena L. Goulden, Rachel K. Crowley
    Clinical Endocrinology.2023; 98(5): 649.     CrossRef
  • Clinical and Histopathological Aspects of MRONJ in Cancer Patients
    George Adrian Ciobanu, Laurențiu Mogoantă, Adrian Camen, Mihaela Ionescu, Daniel Vlad, Ionela Elisabeta Staicu, Cristina Maria Munteanu, Mircea Ionuț Gheorghiță, Răzvan Mercuț, Elena Claudia Sin, Sanda Mihaela Popescu
    Journal of Clinical Medicine.2023; 12(10): 3383.     CrossRef
  • Bisphosphonates and osteonecrosis of the jaws: Clinical and forensic aspects
    Diana Nogueira, Inês Morais Caldas, Ricardo Jorge Dinis-Oliveira
    Archives of Oral Biology.2023; 155: 105792.     CrossRef
  • Correlations between Immune Response and Etiopathogenic Factors of Medication-Related Osteonecrosis of the Jaw in Cancer Patients Treated with Zoledronic Acid
    George Adrian Ciobanu, Laurențiu Mogoantă, Sanda Mihaela Popescu, Mihaela Ionescu, Cristina Maria Munteanu, Ionela Elisabeta Staicu, Răzvan Mercuț, Cristian Corneliu Georgescu, Monica Scrieciu, Daniel Vlad, Adrian Camen
    International Journal of Molecular Sciences.2023; 24(18): 14345.     CrossRef
  • Analysis of the Degree of Information of Dental Surgeons about Antiresorptive Drugs According to the Time Since Graduation in Dentistry
    Flávia Godinho Costa Wanderley Rocha, Roberto Paulo Correia de Araújo
    Pesquisa Brasileira em Odontopediatria e Clínica Integrada.2023;[Epub]     CrossRef
  • Safety and Efficacy of Pamidronate in Neonatal Hypercalcemia Caused by Subcutaneous Fat Necrosis: A Case Report
    Stefano Martinelli, Marco Pitea, Italo Francesco Gatelli, Tara Raouf, Graziano Barera, Ottavio Vitelli
    Frontiers in Pediatrics.2022;[Epub]     CrossRef
  • Zoledronic acid for osteoporosis and associated low-energy fractures
    S. S. Rodionova, A. F. Kolondaev, A. N. Torgashin, I. A. Solomyannik
    Meditsinskiy sovet = Medical Council.2022; (21): 163.     CrossRef
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Case Report
A Case of Intravenous Pamidronate-Related Osteonecrosis of the Jaw in a Patient with Waldenstrom's Macroglobulinemia.
Da Mi Lee, Mi Sun Ann, Tae Ho Kim, Tae Jin Park, Yoon Sok Chung, Joon Seong Park, Seung Il Song, Kyi Beom Lee, Hee Jae Joo
J Korean Endocr Soc. 2008;23(3):210-214.   Published online June 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.3.210
  • 1,628 View
  • 18 Download
  • 1 Crossref
AbstractAbstract PDF
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare, but serious, side effect of bisphosphonate therapy that produces significant morbidity in affected patients. It is characterized by poor wound healing and spontaneous intra-oral soft tissue breakdown, which lead to exposure of necrotic maxillary and mandibular bone.

Citations

Citations to this article as recorded by  
  • Dental sinus tracts mimicking scrofuloderma: cutaneous presentation of underlying bisphosphonate-related osteonecrosis of the jaw
    H.-S. Kang, J.-W. Lee, J.-S. Kim
    Clinical and Experimental Dermatology.2011; 36(6): 624.     CrossRef
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