A Case of Oncogenic Osteomalacia Caused by Chondromyxoid Fibroma.

Oh, Ki Won; Kang, Moo II; Lee, Won Young; Lee, Tae Kyu; Chang, Jae Hyuck; Suh, Jung Pil; Cha, Bong Yun; Lee, Kwang Woo; Son, Ho Young; Kang, Sung Koo; Park, Jeong Mi; Lee, Kyo Young; Rhee, Seung Koo; Woo, Young Kyun

Case Report

Journal of Korean Endocrine Society 1999;14(4):764-770.
Published online January 1, 2001.

A Case of Oncogenic Osteomalacia Caused by Chondromyxoid Fibroma.

Ki Won Oh, Moo II Kang, Won Young Lee, Tae Kyu Lee, Jae Hyuck Chang, Jung Pil Suh, Bong Yun Cha, Kwang Woo Lee, Ho Young Son, Sung Koo Kang, Jeong Mi Park, Kyo Young Lee, Seung Koo Rhee, Young Kyun Woo

¹Department of Internal Medicine, The Catholic University of Korea, College of Medicine, Seoul, Korea.
²Department of Radiology, The Catholic University of Korea, College of Medicine, Seoul, Korea.
³Department of Clinical Pathology, The Catholic University of Korea, College of Medicine, Seoul, Korea.
⁴Department of Orthopedic Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea.

Abstract

Oncogenic osteomalacia is a rare clinicopathological condition. The syndrome is characterized by hypophosphataemic osteomalacia with hyperphosphaturia, low plasma 1,25-dihydroxyvitamin D and normal plasma calcaemia and parathyroid hormone, associated with a tumor, generally of mesenchymal origin. Complete excision of the tumour results in cure of the whole syndrome. Recently we experienced 56-year-old woman with oncogenic osteomalacia caused by a chondromyxoid fibroma of the left foot. We report this case with the review of literatures.

Key Words: Oncogenic osteomalacia, Chondromyxoid fibroma, Hyperphosphaturia, Hypo- phosphatemia