Journal of Korean Endocrine Society 2001;16(2):245-251.
Published online April 1, 2001.
A Case of Hashimotos Thyroiditis with Anti-Triiodothyronine Autoantibody.
Yun Ey Chung, Jeong Hee Han, Seong Jin Lee, Won Ki Min, Ki Young Park, Kun Ku Park, Dae Hyunk Moon, Il Min Ahn
1Department of Internal Medicine, College of Medicine University of Ulsan, Korea.
2Department of Clinical Pathology, College of Medicine University of Ulsan, Korea.
3Department of Nuclear Medicine, College of Medicine University of Ulsan, Korea.
4Asan Institute of Life Science and Technology, Seoul, Korea.
Abstract
Autoantibodies against thyroid hormones can be detected in the sera of patients with both thyroidal and non-thyroidal disorders. These antibodies interfere with the radioimmunoassay of serum total and free thyroid hormone concentrations, resulting in a discrepancy between the measured hormone levels and clinical features. This can in turn lead to an erroneous diagnosis and patients may receive unnecessary treatment from physicians who are unaware of the presence of the autoantibodies. We experienced a woman having Hashimotos' thyroiditis with a spurious elevation of total T3 and free T3 values according to one-step analog-tracer radioimmunoassay who was had been treated as Graves' disease in past. Through the use of a polyethylene glycol precipitation method, she was subsequently revealed to have anti-triiodothyronine autoantibodies. We report this case with a review of related literature.
Key Words: Anti-triiodothyronine autoantibody, Hashimotos thyroiditis


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