Journal of Korean Endocrine Society 2003;18(3):318-324.
Published online June 1, 2003.
A Case of Renal Cell Carcinoma with Thyroid Metastasis.
Hye Seung Jung, Young Joo Park, Hee Sun Chung, Mee Soo Chang, Tae Hoon Jin, Cheol Soo Choi, Sung Woo Park, Tae Young Kim, Do Joon Park, Bo Youn Cho
1Department of Internal Medicine, Seoul National University College of Medicine, Korea.
2Department of Pathology, Seoul National University College of Medicine, Korea.
3Department of Internal Medicine, Seoul Municipal Boramae Hospital, Korea.
4Department of Pathology, Seoul Municipal Boramae Hospital, Korea.
5Department of Otolaryngology, Seoul Municipal Boramae Hospital, Korea.
6Department of Internal Medicine, Hallym University College of Medicine, Korea.
7The Institute of Endocrinology, Nutrition and Metabolism, Seoul National University College of Medicine, Korea.
Metastatic thyroid cancer is uncommon but must be distinguished from primary thyroid cancer because of the differences in management and prognosis. Although renal cell carcinoma is one of the most common tumors that metastasize to the thyroid gland, such a case has never been reported in Korea. We describe the first case of metastatic renal cell carcinoma in the thyroid gland. A 66-year-old man presented with a neck mass detected about 6 weeks previously. He had undergone left nephrectomy due to renal cell carcinoma 8 years before and had remained disease-free thereafter. Computed tomography of the neck showed a 5 cm-sized thyroid mass. Fine needle aspiration cytology revealed some malignant cells containing intranuclear inclusions which were assumed to be papillary thyroid carcinoma. The patient underwent total thyroidectomy. Histologic diagnosis of the thyroid mass was metastatic renal cell carcinoma and further evaluation with chest computed tomography showed two enlarged mediastinal lymph nodes suggesting metastases. The previous history of malignancy should be scrutinized when managing a thyroid mass in patients with a prior or concomitant malignancy, and the possibility of metastasis should be carefully considered.
Key Words: Thyroid metastasis, Renal cell carcinoma

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