Endocrinol Metab > Volume 27(1); 2012 > Article
Endocrinology and Metabolism 2012;27(1):54-58.
DOI: https://doi.org/10.3803/EnM.2012.27.1.54    Published online March 1, 2012.
A Case of Sheehan's Syndrome with Pancytopenia.
Hyun Suk Lee, Byung Woon Kwon, Jin Hyung Han, Hee Jin Kim
Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea. kimhj@dankook.ac.kr
Abstract
Sheehan's syndrome is characterized by varying degrees of anterior pituitary dysfunction due to postpartum ischemic necrosis of the pituitary gland after massive bleeding. The spectrum of clinical presentation of Sheehan's syndrome is broad, with changes from nonspecific complaints, such as weakness, fatigue, and anemia, to severe pituitary insufficiency resulting in coma and death. Normochromic anemia is commonly associated with Sheehan's syndrome, but pancytopenia is rarely observed in patients with Sheehan's syndrome. We describe a 57-year-old woman with Sheehan's syndrome who presented with pancytopenia that was treated by hormone replacement with levothyroxine and glucocorticoid.
Key Words: Glucocorticoids, Hypopituitarism, Pancytopenia, Thyroxine


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