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HOME > Endocrinol Metab > Volume 21(4); 2006 > Article
Review Article Type 2 Diabetes and Mitochondria.
Hyo Jung Choo, Young Gyu Ko
Endocrinology and Metabolism 2006;21(4):266-271
DOI: https://doi.org/10.3803/jkes.2006.21.4.266
Published online: August 1, 2006
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School of Life Sciences and Biotechnology, Korea University, Korea.
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Liver, muscle, and adipose tissue are resistant to insulin action in type 2 diabetes. In spite of intensive studies, few diabetic genes have been identified. Recently, mitochondrial impairment has been observed in the muscle and adipose tissues of type 2 diabetes patients, implying that mitochondrial dysfunction could be a pivotal factor in type 2 diabetes. Here, we discuss mitochondrial malfunction leading to type 2 diabetes.

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