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HOME > Endocrinol Metab > Volume 21(5); 2006 > Article
Case Report A Case of Colon Cancer in Mayer-Rokitansky-Kuster-Hauser (MRKH) Syndrome with Gonadal Agenesis.
Jae Youn Park, Seoung Young Kim, Jin Nam Kim, Seo Jung Yang, Ju Ri Park, Bo Sung Kwan, Dong Jin Kim, Kye Won Lee, Kyung Mook Choi, Sei Hyun Baik, Moon Kyoung Joo, Jin Soo Chang
Endocrinology and Metabolism 2006;21(5):414-418
DOI: https://doi.org/10.3803/jkes.2006.21.5.414
Published online: October 1, 2006
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Department of Internal Medicine, Guro Hospital, Korea University School of Medicine, Korea.

Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is the second frequent cause of primary amenorrhea. There have been several reports concerning gynecologic disease in MRKH syndrome, but there has been no case about a colon cancer in a patient with this condition. A 43 years old woman, who reported primary amenorrhea with sexual infantilism, was evaluated in our department because of lower abdominal pain: she presented with a suprapubic mass. To evaluate the suprapubic abdominal mass and primary amenorrhea, abdominal MRI, colonoscopy and endocrine tests were done. She had no gynecologic organs, and she finally was diagnosed as having colon cancer with the atypical form of MRKH syndrome (bilateral gonadal agenesis 46 XX). To the best of our knowledge this is the first case concerning primary colon cancer in a patient with MRKH syndrome.

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