Endocrinol Metab > Volume 23(3); 2008 > Article
Journal of Korean Endocrine Society 2008;23(3):210-214.
DOI: https://doi.org/10.3803/jkes.2008.23.3.210    Published online June 1, 2008.
A Case of Intravenous Pamidronate-Related Osteonecrosis of the Jaw in a Patient with Waldenstrom's Macroglobulinemia.
Da Mi Lee, Mi Sun Ann, Tae Ho Kim, Tae Jin Park, Yoon Sok Chung, Joon Seong Park, Seung Il Song, Kyi Beom Lee, Hee Jae Joo
1Department of Endocrinology and Metabolism, Ajou University School of Medicine, Korea.
2Department of Hematology-Oncology, Ajou University Schoo of Medicine, Korea.
3Department of Dentistry, Ajou University School of Medicine, Korea.
4Department of Pathology, Ajou University School of Medicine, Korea.
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare, but serious, side effect of bisphosphonate therapy that produces significant morbidity in affected patients. It is characterized by poor wound healing and spontaneous intra-oral soft tissue breakdown, which lead to exposure of necrotic maxillary and mandibular bone.
Key Words: pamidronate, osteonecrosis, mandible

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