Warning: fopen(/home/virtual/enm-kes/journal/upload/ip_log/ip_log_2025-02.txt): failed to open stream: Permission denied in /home/virtual/lib/view_data.php on line 100 Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 101
1Department of Endocrinology and Metabolism, Institute of Endocrinology, National Health Commission Key Laboratory of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China
2Department of Endocrinology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
3Department of Endocrinology, Chifeng College Affiliated Hospital, Chifeng, China
Copyright © 2022 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST
No potential conflict of interest relevant to this article was reported.
AUTHOR CONTRIBUTIONS
Conception or design: T.J., W.T., X.T. Acquisition, analysis, or interpretation of data: T.J., R.W., S.P., X.L., H.Z., X.H. Drafting the work or revising: T.J., X.T. Final approval of the manuscript: T.J., X.T.
Animal | Stage |
Euthyroid group |
Hypothyroid group |
||||
---|---|---|---|---|---|---|---|
TSH, mIU/L | TT4, μg/dL | TT3, ng/dL | TSH, mIU/L | TT4, μg/dL | TT3, ng/dL | ||
Dams | E17 | 0.35±0.14 | 2.81±0.34 | 60.36±9.92 | 4.77±2.01a | 1.15±0.31a | 25.81±8.07a |
P2 | 0.20±0.12 | 2.40±0.73 | 68.28±11.92 | 8.97±2.49a | 1.35±0.92a | 18.56±3.42a | |
P4 | 0.26±0.70 | 1.88±0.34 | 68.00±15.78 | 8.84±1.13a | 1.09±0.30a | 15.98±2.01a | |
P10 | 0.45±0.07 | 1.66±0.40 | 53.26±1.72 | 11.77±1.78a | 0.62±0.08a | 12.36±3.62a | |
Pups | P10 | 0.23±0.17 | 2.28±0.50 | 28.66±6.83 | 5.15±2.25a | 0.56±0.10a | 11.96±2.62a |
Stage | Euthyroid group, g | Hypothyroid group, g |
---|---|---|
E17 | 324.72±18.17 | 331.78±10.77 |
P2 | 286.44±10.66 | 278.12±10.08 |
P4 | 284.32±12.77 | 279.76±5.96 |
P10 | 290.76±8.82 | 280.92±12.48 |
Stage | Euthyroid group, g | Hypothyroid group, g |
---|---|---|
P2 | 7.44±0.82 | 5.34±0.84a |
P4 | 11.81±1.42 | 6.85±0.77a |
P10 | 18.80±1.00 | 11.33±1.32a |
Animal | Stage | Euthyroid group |
Hypothyroid group |
||||
---|---|---|---|---|---|---|---|
TSH, mIU/L | TT4, μg/dL | TT3, ng/dL | TSH, mIU/L | TT4, μg/dL | TT3, ng/dL | ||
Dams | E17 | 0.35±0.14 | 2.81±0.34 | 60.36±9.92 | 4.77±2.01 |
1.15±0.31 |
25.81±8.07 |
P2 | 0.20±0.12 | 2.40±0.73 | 68.28±11.92 | 8.97±2.49 |
1.35±0.92 |
18.56±3.42 |
|
P4 | 0.26±0.70 | 1.88±0.34 | 68.00±15.78 | 8.84±1.13 |
1.09±0.30 |
15.98±2.01 |
|
P10 | 0.45±0.07 | 1.66±0.40 | 53.26±1.72 | 11.77±1.78 |
0.62±0.08 |
12.36±3.62 |
|
Pups | P10 | 0.23±0.17 | 2.28±0.50 | 28.66±6.83 | 5.15±2.25 |
0.56±0.10 |
11.96±2.62 |
Stage | Euthyroid group, g | Hypothyroid group, g |
---|---|---|
E17 | 324.72±18.17 | 331.78±10.77 |
P2 | 286.44±10.66 | 278.12±10.08 |
P4 | 284.32±12.77 | 279.76±5.96 |
P10 | 290.76±8.82 | 280.92±12.48 |
Stage | Euthyroid group, g | Hypothyroid group, g |
---|---|---|
P2 | 7.44±0.82 | 5.34±0.84 |
P4 | 11.81±1.42 | 6.85±0.77 |
P10 | 18.80±1.00 | 11.33±1.32 |
Values are expressed as mean±standard deviation ( TSH, thyroid-stimulating hormone; TT4, total thyroxine; TT3, total triiodothyronine; E, embryonic; P, postnatal day.
Values are expressed as mean±standard deviation ( E, embryonic day; P, postnatal day.
Values are expressed as mean±standard deviation ( P, postnatal day.