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1Division of Endocrinology and Metabolism, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea
2Division of Endocrinology and Metabolism, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea
3Division of Endocrinology and Metabolism, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Seoul, Korea
4Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
5Division of Endocrinology and Metabolism, Department of Internal Medicine, Ajou University School of Medicine, Suwon, Korea
6Division of Endocrinology and Metabolism, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Korea
Copyright © 2020 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST
No potential conflict of interest relevant to this article was reported.
AUTHOR CONTRIBUTIONS
Conception or design: I.K.J., S.W.K. Acquisition, analysis, or interpretation of data: I.K.J., J.K.B., J.N., S.W.K., Y.S.C., T.S.P., S.W.K. Drafting the work or revising: I.K.J. Final approval of the manuscript: I.K.J., S.W.K.
Age, yr | Male (n=180) | Female (n=172) | Reference | |||||||||||
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No. | Mean | SD | Min | Max | No. | Mean | SD | Min | Max | Mean −2SD | Mean | Mean +2SD | ||
IGF-I, ng/mL | 21–30 | 25 | 386.42 | 114.58 | 189.00 | 596.00 | 26 | 408.26 | 131.10 | 227.00 | 651.00 | 162.8 | 443.0 | 723.2 |
31–40 | 44 | 324.64 | 112.82 | 102.50 | 575.00 | 44 | 330.76 | 128.58 | 94.00 | 604.00 | 115.3 | 325.1 | 534.9 | |
41–50 | 35 | 282.34 | 153.44 | 64.00 | 646.00 | 34a | 283.70a | 125.50a | 70.00 | 536.00 | 80.9 | 261.7 | 442.4 | |
9a,b | 194.39a | 113.14a | 74.00 | 384.00 | ||||||||||
51–60 | 49 | 281.14 | 124.79 | 64.50 | 562.00 | 36a | 269.64a | 138.77a | 66.50 | 464.00 | 61.5 | 236.0 | 410.4 | |
25a,b | 186.64a | 111.00a | 41.00 | 419.00 | ||||||||||
61–70 | 27 | 214.26 | 112.23 | 37.00 | 429.00 | 32a | 205.07a | 129.37a | 34.00 | 495.00 | 48.7 | 208.8 | 368.8 | |
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IGFBP-3, ng/mL | 21–30 | 25 | 3,350.29 | 514.36 | 2,232.50 | 4,292.50 | 26 | 3,837.43 | 840.27 | 2,091.50 | 5,297.50 | 1,965.8 | 4,236.6 | 6,507.3 |
31–40 | 44 | 3,506.39 | 549.26 | 2,562.50 | 4,948.50 | 44 | 3,745.17 | 510.40 | 2,985.00 | 5,112.50 | 1,693.0 | 3,493.0 | 5,293.0 | |
41–50 | 35 | 3,354.80 | 443.49 | 2,473.00 | 4,674.50 | 34 | 3,514.76 | 654.17 | 2,727.50 | 5,118.00 | 2,158.0 | 3,152.0 | 4,146.0 | |
9b | 3,238.33 | 590.98 | 2,239.00 | 4,136.50 | ||||||||||
51–60 | 48 | 3,473.66 | 637.91 | 2,304.00 | 4,970.50 | 35 | 3,316.41 | 393.13 | 2,892.50 | 4,130.00 | 2,088.0 | 2,966.0 | 3,844.0 | |
25b | 3,594.50 | 888.44 | 2,314.50 | 5,772.00 | ||||||||||
61–70 | 27 | 3,272.83 | 671.64 | 2,048.50 | 4,502.00 | 32 | 3,469.78 | 684.81 | 1,975.00 | 5,135.00 |