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1Department of Internal Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea
2Department of Internal Medicine, Chonnam National University Hwasun Hospital, Hwasun, Korea
3Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
4Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Copyright © 2020 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST
No potential conflict of interest relevant to this article was reported.
AUTHOR CONTRIBUTIONS
Conception or design: M.K., M.J.J., D.J.L., H.C.K., Y.K.S., T.Y.K., B.H.K. Acquisition, analysis, or interpretation of data: M.K., J.H.Y., J.A., M.J.J., H.K.K., D.J.L., H.C.K., I.J.K., Y.K.S., T.Y.K., B.H.K. Drafting the work or revising: M.K., J.H.Y., M.J.J., H.K.K., D.J.L., H.C.K., I.J.K., Y.K.S., T.Y.K., B.H.K. Final approval of the manuscript: M.K., J.H.Y., J.A., M.J.J., H.K.K., D.J.L., H.C.K., I.J.K., Y.K.S., T.Y.K., B.H.K.
Tumor response was assessed using the Response Criteria in Solid Tumors, version 1.1. The objective response rate was calculated as complete response (CR) plus partial response (PR). The disease control rate was calculated as CR plus PR plus stable disease ≥24 weeks. The biochemical response was defined by decreases of 50% or more in serum calcitonin and CEA levels which were maintained for at least 4 weeks.
CEA, carcinoembryonic antigen.