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1Department of Internal Medicine, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
2Cardiovascular and Metabolic Disease Center (CMDC), Inje University, Busan, Korea.
3Department of Neurology, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
Copyright © 2019 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported.
SGLT2, sodium-glucose cotransporter 2; EMPA-REG, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients-Removing Excess Glucose; CVD, cardiovascular disease; CANVAS, Canagliflozin Cardiovascular Assessment Study; CV, cardiovascular; DECLARE-TIMI 53, Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 53; GLP-1RA, glucagon-like peptide 1 receptor agonist; ELIXA, Evaluation of Lixisenatide in Acute Coronary Syndrome; ACS, acute coronary syndrome; LEADER, Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results; SUSTAIN-6, Semaglutide in Subjects with Type 2 Diabetes; EXSCEL, Exenatide Study of Cardiovascular Event Lowering; HARMONY, Albiglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Cardiovascular Disease.
PositiveHR, hazard ratio; CI, confidence interval; SGLT2, sodium-glucose cotransporter 2; EMPA-REG, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients-Temoving Excess Glucose; CANVAS, Canagliflozin Cardiovascular Assessment Study; DECLARE-TIMI 53, Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 53; GLP-1RA, glucagon-like peptide 1 receptor agonist; ELIXA, Evaluation of Lixisenatide in Acute Coronary Syndrome; LEADER, Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results; SUSTAIN-6, Semaglutide in Subjects with Type 2 Diabetes; EXSCEL, Exenatide Study of Cardiovascular Event Lowering; HARMONY, Albiglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Cardiovascular Disease.
CVOT, cardiovascular outcome trial; HR, hazard ratio; CI, confidence interval; MI, myocardial infarction; HF, heart failure; EMPA-REG, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients-Temoving Excess Glucose; CANVAS, Canagliflozin Cardiovascular Assessment Study; DECLARE-TIMI 53, Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 53; ELIXA, Evaluation of Lixisenatide in Acute Coronary Syndrome; LEADER, Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results; SUSTAIN-6, Semaglutide in Subjects with Type 2 Diabetes; EXSCEL, Exenatide Study of Cardiovascular Event Lowering; HARMONY, Albiglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Cardiovascular Disease.
SGLT2, sodium-glucose cotransporter 2; EMPA-REG, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients-Removing Excess Glucose; CVD, cardiovascular disease; CANVAS, Canagliflozin Cardiovascular Assessment Study; CV, cardiovascular; DECLARE-TIMI 53, Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 53; GLP-1RA, glucagon-like peptide 1 receptor agonist; ELIXA, Evaluation of Lixisenatide in Acute Coronary Syndrome; ACS, acute coronary syndrome; LEADER, Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results; SUSTAIN-6, Semaglutide in Subjects with Type 2 Diabetes; EXSCEL, Exenatide Study of Cardiovascular Event Lowering; HARMONY, Albiglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Cardiovascular Disease.
PositiveHR, hazard ratio; CI, confidence interval; SGLT2, sodium-glucose cotransporter 2; EMPA-REG, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients-Temoving Excess Glucose; CANVAS, Canagliflozin Cardiovascular Assessment Study; DECLARE-TIMI 53, Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 53; GLP-1RA, glucagon-like peptide 1 receptor agonist; ELIXA, Evaluation of Lixisenatide in Acute Coronary Syndrome; LEADER, Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results; SUSTAIN-6, Semaglutide in Subjects with Type 2 Diabetes; EXSCEL, Exenatide Study of Cardiovascular Event Lowering; HARMONY, Albiglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Cardiovascular Disease.
CVOT, cardiovascular outcome trial; HR, hazard ratio; CI, confidence interval; MI, myocardial infarction; HF, heart failure; EMPA-REG, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients-Temoving Excess Glucose; CANVAS, Canagliflozin Cardiovascular Assessment Study; DECLARE-TIMI 53, Dapagliflozin Effect on Cardiovascular Events-Thrombolysis in Myocardial Infarction 53; ELIXA, Evaluation of Lixisenatide in Acute Coronary Syndrome; LEADER, Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results; SUSTAIN-6, Semaglutide in Subjects with Type 2 Diabetes; EXSCEL, Exenatide Study of Cardiovascular Event Lowering; HARMONY, Albiglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Cardiovascular Disease.