Articles in 'Endocrinology and Metabolism' in 2014

Article information

Endocrinol Metab. 2015;30(1):47-52
Publication date (electronic) : 2015 March 27
doi : https://doi.org/10.3803/EnM.2015.30.1.47
Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Corresponding author: Won-Young Lee. Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 110-746, Korea. Tel: +82-2-2001-2579, Fax: +82-2-2001-2049, drlwy@hanmail.net

INTRODUCTION

In 2014, the journal published many excellent articles in the fields of endocrinology and metabolism. I believe that these works increased scientific knowledge and the standards of medical care. Updated information is freely available to readers. I would like to briefly introduce a number of excellent articles published in 2014 in 'Endocrinology and Metabolism' (Endocrinol Metab).

ARTICLES ON THYROID DISEASE

Prof. YJ Park, deputy editor of 'Endocrinology and Metabolism,' wrote a review on the prevalence of, and risk factors for, subclinical thyroid disease in Korea; this analysis was particularly clear [1]. Several review articles on thyroid cancer appeared in the third issue of 2014: "Molecular pathogenesis and targeted therapies in well-differentiated thyroid carcinoma"; "Current status and future perspectives in differentiated thyroid cancer"; "Can robotic thyroidectomy be performed safely in thyroid carcinoma patients?"; and "Radioiodine therapy in differentiated thyroid cancer: the first targeted therapy in oncology" [2,3,4,5]. Prof. W Teng reviewed nationwide Chinese data and reported that excess iodine can trigger hypothyroidism and autoimmune thyroiditis, especially in susceptible populations with recurring thyroid disease, the elderly, fetuses, and neonates [6].

Prof. EH Jeon and Prof. ED Jung published an original article entitled "Diagnostic whole-body scan may not be necessary for intermediate-risk patients with differentiated thyroid cancer after low-dose (30 mCi) radioactive iodide ablation," involving a study performed on 438 subjects with differentiated thyroid cancer. They suggested that diagnostic I-131 whole-body scanning after radioactive iodide ablation may not be necessary in intermediate-risk patients with differentiated thyroid cancer [7]. Prof. EJ Lee et al. described the biochemical factors prognostic of subclinical hypothyroidism in newly diagnosed patients [8]. Prof. KR Hyun, Prof. S Kang, and Prof. S Lee analyzed the social costs of thyroid disease in Korea over the last 10 years in their article entitled "Cost-of-illness trends associated with thyroid disease in Korea" [9]. Prof. JI Son et al. analyzed thyroid fine-needle aspiration specimens from 469 patients and published a paper entitled "Insufficient experience in thyroid fine-needle aspiration leads to misdiagnosis of thyroid cancer" [10]. Prof. M Sanjari et al. completed a study involving school-aged children in Iran, and found that cobalt deficiency is one reason why goiter persists in that country [11]. Other original articles on thyroid disease also appeared in 2014 [12,13,14,15,16].

ARTICLES ON DIABETES AND OBESITY

In a review article, Prof. S Lim elegantly showed that ectopic fat accumulation by visceral organs is associated with insulin resistance [17]. He received the Namgok Award for his work, and wrote an update of the effects of ectopic fat accumulation on cardiometabolic and renal disorders. Prof. I Kojima, editor-in-chief of 'Endocrine Journal,' reviewed signal transduction systems activated by sugar molecules in an extragustatory tissue, pancreatic β-cells [18]. Prof. KG Park reviewed transcriptional regulation of fibroblast growth factor 21 (FGF21) expression [19]. Prof. IK Lyoo discussed the characteristics of the cognitive impairment observed in type 2 diabetic patients and summarized the outcomes of recent neuroimaging studies of human diabetes-associated brain deficits [20]. Adipose tissue plays a key role in energy storage. Prof. JB Kim described the microRNA-mediated regulatory mechanisms of adipocyte differentiation [21]. The fourth issue of 2014 was a special issue on obesity. Five review articles presented recent treatment guidelines and new findings in the field [22,23,24,25,26]. Prof. EJ Rhee analyzed data collected during a health-screening program, and found that renal function was negatively correlated with the extent of coronary artery calcification [27]. Very topical articles on metabolic syndrome, fatty liver, and diabetes prediction appeared in other issues of 2014 [28,29,30,31].

ARTICLES ON BONE, PITUITARY, AND OTHER ENDOCRINE DISEASES

Prof. S Fukumoto of the University of Tokyo hospital reviewed the methods by which FGF23-producing tumors may be diagnosed in patients with tumor-induced osteomalacia [32]. Prof. JT Lee found, in a review, that F-18 fluorodeoxyglucose positron emission tomography/computed tomography (CT) was highly accurate (compared to CT or magnetic resonance imaging) when used for the differential diagnosis of an adrenal mass, especially when combined with the other two imaging modalities [33]. New radiological methods are under development, and relevant studies were cited in the review. Prof. MJ Lee et al. published a study entitled "Testosterone replacement and bone mineral density in male pituitary tumor patients," which showed that testosterone replacement therapy improved the bone mineral density of postoperative hypogonadal patients with pituitary tumors [34]. Another article featuring genetic analysis presented an extremely rare case of intrasellar cavernous hemangioma [35]. A paper entitled "Genetic and epigenetic analysis in Korean patients with multiple endocrine neoplasia type 1," showed that genotype and phenotype are uniquely associated in Korean multiple endocrine neoplasia type 1 patients [36]. Another study established dopamine agonists as the first-line treatment for prolactinoma, and reported that cabergoline triggered reductions in tumor volume, and normalization of prolactin levels, evident 3 months after treatment commenced. These responses were also predictive of later outcomes, as reported in an original article entitled "Early prediction of long-term response to cabergoline in patients with macroprolactinomas" [37]. An article entitled "Testosterone deficiency associated with poor glycemic control in Korean male diabetics" explored the relationship between testosterone deficiency and the levels of diabetes markers [38]. Other original articles on pituitary, adrenal, parathyroid, and pancreatic diseases appeared in 2014 issues [39,40,41,42,43].

BASIC RESEARCH ARTICLES

A study entitled "Curcumin enhances docetaxel-induced apoptosis of 8505C anaplastic thyroid carcinoma cells" reported that curcumin enhanced the antitumor activity of docetaxel used to treat anaplastic thyroid cancer, suggesting that curcumin may be an attractive candidate drug [44]. An article entitled "Correlation between expression of glucose transporters in granulosa cells and oocyte quality in women with polycystic ovary syndrome" defined the expression patterns of all 13 members of the GLUT family in human granulosa cells and reported that insulin sensitivity regulated GLUT expression in the granulosa cells of polycystic ovary syndrome patients [45]. An experimental study entitled "Functional role of Parkin against oxidative stress in neural cells" explored the role of Parkin in protecting against oxidative stress in neuronal cells that had differentiated from Parkin-knockout embryonic stem cells [46]. In another experimental work entitled "Short-term caloric restriction does not reduce bone mineral density in rats with early type 2 diabetes," bone mineral density was maintained in Otsuka Long-Evans Tokushima Fatty rats after short-term caloric restriction induced weight loss [47]. An article entitled "Insulin phosphorylates tyrosine residue 464 of Tub and translocate Tubby into the nucleus in HIRcB cells" reported that Tub contains a tyrosine-phosphorylation site that is modified in response to insulin and insulin-like growth factor [48]. An experimental study involving rats separated from their mothers as neonates suggested that prolonged access to highly palatable food during adolescence and youth partly improved anxiety-related symptoms; the hypothalamic-pituitary-adrenal axis was more functional than in controls [49]. An article entitled "A novel cytosolic isoform of mitochondrial trans-2-Enoyl-CoA reductase enhances peroxisome proliferator-activated receptor α activity" appeared in the third issue of 2014 [50]. Prof. MJ Moon reported that a novel glucagon-like peptide-1 (GLP-1) analog, Xenopus GLP-E4, improved β-cell function in an article entitled "A novel long-acting glucagon-like peptide-1 agonist with improved efficacy in insulin secretion and β-cell growth" [51]. Several updates on research work in neurons and brain vessels have also been published [52,53,54,55,56,57,58]. An experimental study involving skeletal muscle cells revealed that Vav3 plays a critical role in glucose regulation under high-glucose conditions [59]. Other excellent articles on basic endocrine research have also been published [60,61,62]. Finally, interesting case reports on patients with various endocrine diseases appeared in 2014 in 'Endocrinology and Metabolism' [63,64,65,66,67,68,69,70,71,72].

CONCLUSIONS

In this editorial, I would like to express my deep appreciation to all those who have devoted time and effort to our journal. I deeply thank all readers, authors, editors, and board members of the Korean Endocrine Society. Their support and continued efforts made it possible to publish many excellent articles. I hope that readers will continue to support 'Endocrinology and Metabolism' in 2015.

Notes

CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported.

References

1. Kim YA, Park YJ. Prevalence and risk factors of subclinical thyroid disease. Endocrinol Metab 2014;29:20–29.
2. Kim JG. Molecular pathogenesis and targeted therapies in well-differentiated thyroid carcinoma. Endocrinol Metab 2014;29:211–216.
3. Kim TY, Kim WG, Kim WB, Shong YK. Current status and future perspectives in differentiated thyroid cancer. Endocrinol Metab 2014;29:217–225.
4. Chai YJ, Lee KE, Youn YK. Can robotic thyroidectomy be performed safely in thyroid carcinoma patients? Endocrinol Metab 2014;29:226–232.
5. Chung JK, Cheon GJ. Radioiodine therapy in differentiated thyroid cancer: the first targeted therapy in oncology. Endocrinol Metab 2014;29:233–239.
6. Sun X, Shan Z, Teng W. Effects of increased iodine intake on thyroid disorders. Endocrinol Metab 2014;29:240–247.
7. Jeon EJ, Jung ED. Diagnostic whole-body scan may not be necessary for intermediate-risk patients with differentiated thyroid cancer after low-dose (30 mCi) radioactive iodide ablation. Endocrinol Metab 2014;29:33–39.
8. Lee MW, Shin DY, Kim KJ, Hwang S, Lee EJ. The biochemical prognostic factors of subclinical hypothyroidism. Endocrinol Metab 2014;29:154–162.
9. Hyun KR, Kang S, Lee S. Cost-of-illness trends associated with thyroid disease in Korea. Endocrinol Metab 2014;29:257–269.
10. Son JI, Rhee SY, Woo JT, Park WS, Byun JK, Kim YJ, Byun JM, Chin SO, Chon S, Oh S, Kim SW, Kim YS. Insufficient experience in thyroid fine-needle aspiration leads to misdiagnosis of thyroid cancer. Endocrinol Metab 2014;29:293–299.
11. Sanjari M, Gholamhoseinian A, Nakhaee A. The association between cobalt deficiency and endemic goiter in school-aged children. Endocrinol Metab 2014;29:307–311.
12. Canete EJ, Sison-Pena CM, Jimeno CA. Clinicopathological, biochemical, and sonographic features of thyroid nodule predictive of malignancy among adult Filipino patients in a tertiary hospital in the Philippines. Endocrinol Metab 2014;29:489–497.
13. Hong AR, Lim JA, Kim TH, Choi HS, Yoo WS, Min HS, Won JK, Lee KE, Jung KC, Park do J, Park YJ. The frequency and clinical implications of the BRAF(V600E) mutation in papillary thyroid cancer patients in Korea over the past two decades. Endocrinol Metab 2014;29:505–513.
14. Choi YM, Kim TY, Jang EK, Kwon H, Jeon MJ, Kim WG, Shong YK, Kim WB. Standardized thyroid cancer mortality in Korea between 1985 and 2010. Endocrinol Metab 2014;29:530–535.
15. Jung MJ, Kwon SK. Expression of glucagon-like Peptide-1 receptor in papillary thyroid carcinoma and its clinicopathologic significance. Endocrinol Metab 2014;29:536–544.
16. Kim JH, Kim NK, Oh YL, Kim HJ, Kim SY, Chung JH, Kim SW. The validity of ultrasonography-guided fine needle aspiration biopsy in thyroid nodules 4 cm or larger depends on ultrasonography characteristics. Endocrinol Metab 2014;29:545–552.
17. Lim S. Ectopic fat assessment focusing on cardiometabolic and renal risk. Endocrinol Metab 2014;29:1–4.
18. Kojima I, Nakagawa Y, Ohtsu Y, Medina A, Nagasawa M. Sweet taste-sensing receptors expressed in pancreatic beta-cells: sweet molecules act as biased agonists. Endocrinol Metab 2014;29:12–19.
19. Bae KH, Kim JG, Park KG. Transcriptional regulation of fibroblast growth factor 21 expression. Endocrinol Metab 2014;29:105–111.
20. Lee JH, Choi Y, Jun C, Hong YS, Cho HB, Kim JE, Lyoo IK. Neurocognitive changes and their neural correlates in patients with type 2 diabetes mellitus. Endocrinol Metab 2014;29:112–121.
21. Son YH, Ka S, Kim AY, Kim JB. Regulation of adipocyte differentiation via microRNAs. Endocrinol Metab 2014;29:122–135.
22. Kim MK, Lee WY, Kang JH, Kang JH, Kim BT, Kim SM, Kim EM, Suh SH, Shin HJ, Lee KR, Lee KY, Lee SY, Lee SY, Lee SK, Lee CB, Chung S, Jeong IK, Hur KY, Kim SS, Woo JT. Committee of Clinical Practice Guidelines; Korean Society for the Study of Obesity. 2014 clinical practice guidelines for overweight and obesity in Korea. Endocrinol Metab 2014;29:405–409.
23. Jeon WS, Park CY. Antiobesity pharmacotherapy for patients with type 2 diabetes: focus on long-term management. Endocrinol Metab 2014;29:410–417.
24. Yoon YS, Oh SW. Optimal waist circumference cutoff values for the diagnosis of abdominal obesity in Korean adults. Endocrinol Metab 2014;29:418–426.
25. Seo MH, Rhee EJ. Metabolic and cardiovascular implications of a metabolically healthy obesity phenotype. Endocrinol Metab 2014;29:427–434.
26. Han HS, Choi D, Choi S, Koo SH. Roles of protein arginine methyltransferases in the control of glucose metabolism. Endocrinol Metab 2014;29:435–440.
27. Chae HB, Lee SY, Kim NH, Han KJ, Lee TH, Jang CM, Yoo KM, Park HJ, Lee MK, Jeon WS, Park SE, Moon HS, Park CY, Lee WY, Oh KW, Park SW, Rhee EJ. Age is the strongest effector for the relationship between estimated glomerular filtration rate and coronary artery calcification in apparently healthy Korean adults. Endocrinol Metab 2014;29:312–319.
28. Mirmiran P, Bahadoran Z, Azizi F. Lipid accumulation product is associated with insulin resistance, lipid peroxidation, and systemic inflammation in type 2 diabetic patients. Endocrinol Metab 2014;29:443–449.
29. Jeong DW, Lee HW, Cho YH, Yi DW, Lee SY, Son SM, Kang YH. Comparison of serum ferritin and vitamin d in association with the severity of nonalcoholic Fatty liver disease in Korean adults. Endocrinol Metab 2014;29:479–488.
30. Han KJ, Lee SY, Kim NH, Chae HB, Lee TH, Jang CM, Yoo KM, Park HJ, Lee MK, Jeon WS, Park SE, Park CY, Lee WY, Oh KW, Park SW, Rhee EJ. Increased risk of diabetes development in subjects with the hypertriglyceridemic waist phenotype: a 4-year longitudinal study. Endocrinol Metab 2014;29:514–521.
31. Suh S, Baek J, Bae JC, Kim KN, Park MK, Kim DK, Cho NH, Lee MK. Sex factors in the metabolic syndrome as a predictor of cardiovascular disease. Endocrinol Metab 2014;29:522–529.
32. Fukumoto S. Diagnostic modalities for FGF23-producing tumors in patients with tumor-induced osteomalacia. Endocrinol Metab 2014;29:136–143.
33. Lee HJ, Lee J. Differential diagnosis of adrenal mass using imaging modality: special emphasis on f-18 fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography. Endocrinol Metab 2014;29:5–11.
34. Lee MJ, Ryu HK, An SY, Jeon JY, Lee JI, Chung YS. Testosterone replacement and bone mineral density in male pituitary tumor patients. Endocrinol Metab 2014;29:48–53.
35. Lee DM, Yu SH, Yoon HH, Lee KL, Eom YS, Lee K, Kim BJ, Kim YS, Park Ie B, Kim KW, Lee S. Genetic analysis of multiple endocrine neoplasia type 1 (MEN1) leads to misdiagnosis of an extremely rare presentation of intrasellar cavernous hemangioma as MEN1. Endocrinol Metab 2014;29:146–153.
36. Chung YJ, Hwang S, Jeong JJ, Song SY, Kim SH, Rhee Y. Genetic and epigenetic analysis in Korean patients with multiple endocrine neoplasia type 1. Endocrinol Metab 2014;29:270–279.
37. Lee Y, Ku CR, Kim EH, Hong JW, Lee EJ, Kim SH. Early prediction of long-term response to cabergoline in patients with macroprolactinomas. Endocrinol Metab 2014;29:280–292.
38. Kim JS, Kim BS, Jeon JY, Choi YJ, Chung YS. Testosterone deficiency associated with poor glycemic control in Korean male diabetics. Endocrinol Metab 2014;29:300–306.
39. Park JY, Kim JH, Kim SW, Chung JH, Min YK, Lee MS, Lee MK, Kim KW. Using growth hormone levels to detect macroadenoma in patients with acromegaly. Endocrinol Metab 2014;29:450–456.
40. Kim BY, Chun AR, Kim KJ, Jung CH, Kang SK, Mok JO, Kim CH. Clinical characteristics and metabolic features of patients with adrenal incidentalomas with or without subclinical Cushing's syndrome. Endocrinol Metab 2014;29:457–463.
41. Cho E, Chang JM, Yoon SY, Lee GT, Ku YH, Kim HI, Lee MC, Lee GH, Kim MJ. Preoperative localization and intraoperative parathyroid hormone assay in Korean patients with primary hyperparathyroidism. Endocrinol Metab 2014;29:464–469.
42. Park SM, Bae JC, Joung JY, Cho YY, Kim TH, Jin SM, Suh S, Hur KY, Kim KW. Clinical characteristics, management, and outcome of 22 cases of primary hypophysitis. Endocrinol Metab 2014;29:470–478.
43. Ahn CH, Kim LK, Lee JE, Jung CH, Min SH, Park KS, Kim SY, Cho YM. Clinical implications of various criteria for the biochemical diagnosis of insulinoma. Endocrinol Metab 2014;29:498–504.
44. Hong JM, Park CS, Nam-Goong IS, Kim YS, Lee JC, Han MW, Choi JI, Kim YI, Kim ES. Curcumin enhances docetaxel-induced apoptosis of 8505C anaplastic thyroid carcinoma cells. Endocrinol Metab 2014;29:54–61.
45. Kim E, Seok HH, Lee SY, Lee DR, Moon J, Yoon TK, Lee WS, Lee KA. Correlation between expression of glucose transporters in granulosa cells and oocyte quality in women with polycystic ovary syndrome. Endocrinol Metab 2014;29:40–47.
46. Hwang M, Lee JM, Kim Y, Geum D. Functional role of parkin against oxidative stress in neural cells. Endocrinol Metab 2014;29:62–69.
47. Jeon YK, Kim WJ, Shin MJ, Chung HY, Kim SS, Kim BH, Kim SJ, Kim YK, Kim IJ. Short-term caloric restriction does not reduce bone mineral density in rats with early type 2 diabetes. Endocrinol Metab 2014;29:70–76.
48. Kim JW, Kim HS, Kim SD, Park JY. Insulin phosphorylates tyrosine residue 464 of tub and translocates tubby into the nucleus in HIRcB cells. Endocrinol Metab 2014;29:163–168.
49. Lee JH, Kim JY, Jahng JW. Highly palatable food during adolescence improves anxiety-like behaviors and hypothalamic-pituitary-adrenal axis dysfunction in rats that experienced neonatal maternal separation. Endocrinol Metab 2014;29:169–178.
50. Kim DG, Yoo JC, Kim E, Lee YS, Yarishkin OV, Lee da Y, Lee KH, Hong SG, Hwang EM, Park JY. A novel cytosolic isoform of mitochondrial trans-2-enoyl-CoA reductase enhances peroxisome proliferator-activated receptor alpha activity. Endocrinol Metab 2014;29:185–194.
51. Kim HY, Hwang JI, Moon MJ, Seong JY. A novel long-acting glucagon-like peptide-1 agonist with improved efficacy in insulin secretion and beta-cell growth. Endocrinol Metab 2014;29:320–327.
52. Seong I, Kim J. Gene expression regulation by agonist-independent constitutive signaling of melanocortin-1 receptor. Endocrinol Metab 2014;29:179–184.
53. Cheon SH, Yan BC, Chen BH, Park JH, Ahn JH, Kim IH, Lee JC, Park YS, Kim MJ, Lee YL, Cho JH, Won MH. Accelerated and exacerbated effects of high dietary fat on neuronal damage induced by transient cerebral ischemia in the gerbil septum. Endocrinol Metab 2014;29:328–335.
54. Park SJ, Chung YH, Lee JH, Dang DK, Nam Y, Jeong JH, Kim YS, Nabeshima T, Shin EJ, Kim HC. Growth hormone-releaser diet attenuates cognitive dysfunction in klotho mutant mice via insulin-like growth factor-1 receptor activation in a genetic aging model. Endocrinol Metab 2014;29:336–348.
55. Lee ES, Kim WR, Kim Y, Lee HW, Kim H, Sun W. Polarized and stage-dependent distribution of immunoreactivity for novel PDZ-binding protein Preso1 in adult neurogenic regions. Endocrinol Metab 2014;29:349–355.
56. Yoo SJ, Nakra NK, Ronnett GV, Moon C. Protective effects of inducible HO-1 on oxygen toxicity in rat brain endothelial microvessel cells. Endocrinol Metab 2014;29:356–362.
57. Park I, Lee Y, Kim HD, Kim K. Effect of resveratrol, a SIRT1 activator, on the interactions of the CLOCK/BMAL1 complex. Endocrinol Metab 2014;29:379–387.
58. Lee JY, Yune TY. Ghrelin inhibits oligodendrocyte cell death by attenuating microglial activation. Endocrinol Metab 2014;29:371–378.
59. Sha J, Na J, Lee JO, Kim N, Lee SK, Kim JH, Moon JW, Kim SJ, Lee HJ, Choi JI, Park SH, Kim HS. Vav3, a GEF for RhoA, plays a critical role under high glucose conditions. Endocrinol Metab 2014;29:363–370.
60. Hong SW, Lee J, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY. Activation of AMP-activated protein kinase attenuates tumor necrosis factor-alpha-induced lipolysis via protection of perilipin in 3T3-L1 adipocytes. Endocrinol Metab 2014;29:553–560.
61. Lee YK, Park I, Lee H. Partial hepatectomy in acetylation-deficient BubR1 mice corroborates that chromosome missegregation initiates tumorigenesis. Endocrinol Metab 2014;29:561–566.
62. Jeon YK, Bae MJ, Kim JI, Kim JH, Choi SJ, Kwon SK, An JH, Kim SS, Kim BH, Kim YK, Kim IJ. Expression of glucagon-like peptide 1 receptor during osteogenic differentiation of adipose-derived stem cells. Endocrinol Metab 2014;29:567–573.
63. Jo HJ, Kim YH, Shin DH, Kim MJ, Lee SJ, Jeon DO, Im SG, Jang SK, Choi JY. Hyponatremia after thyroid hormone withdrawal in a patient with papillary thyroid carcinoma. Endocrinol Metab 2014;29:77–82.
64. Eun CR, Ahn JH, Seo JA, Kim NH. Pheochromocytoma with markedly abnormal liver function tests and severe leukocytosis. Endocrinol Metab 2014;29:83–90.
65. Jeong HK, An JH, Kim HS, Cho EA, Han MG, Moon JS, Kim HK, Kang HC. Hypoparathyroidism and subclinical hypothyroidism with secondary hemochromatosis. Endocrinol Metab 2014;29:91–95.
66. Choi HS, Kim MJ, Moon CH, Yoon JH, Ku HR, Kang GW, Na , II , Lee SS, Lee BC, Park YJ, Kim HI, Ku YH. Medullary thyroid carcinoma with ectopic adrenocorticotropic hormone syndrome. Endocrinol Metab 2014;29:96–100.
67. Kang YE, Hong JH, Kim J, Joung KH, Kim HJ, Ku BJ, Kim KS. A novel PHEX gene mutation in a patient with sporadic hypophosphatemic rickets. Endocrinol Metab 2014;29:195–201.
68. Lee SW, Lee EK, Yun T, Won YW, Ko EJ, Choi M, Choi SI, Park SS, Hong EK. Recurrent hypoglycemia triggered by sorafenib therapy in a patient with hemangiopericytoma. Endocrinol Metab 2014;29:202–205.
69. Yun KJ, Kim W, Kim EH, Kim MH, Lim DJ, Kang MI, Cha BY. Accelerated disease progression after discontinuation of sorafenib in a patient with metastatic papillary thyroid cancer. Endocrinol Metab 2014;29:388–393.
70. Choi JE, Lee HR, Ohn JH, Moon MK, Park J, Lee SJ, Choi MG, Yoo HJ, Kim JH, Hong EG. Adult multisystem langerhans cell histiocytosis presenting with central diabetes insipidus successfully treated with chemotherapy. Endocrinol Metab 2014;29:394–399.
71. Kwon H, Kim H, Park S, Song DE, Kim WG, Kim TY, Shong YK, Kim WB. Solitary skin metastasis of papillary thyroid carcinoma. Endocrinol Metab 2014;29:579–583.
72. Kim JK, Kim BH, Baek SM, Shin DH, Kim WJ, Jeon YK, Kim SS, Kim IJ. Incidentally detected inoperable malignant pheochromocytoma with hepatic metastasis treated by transcatheter arterial chemoembolization. Endocrinol Metab 2014;29:584–589.

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