Journal of Korean Endocrine Society 1997;12(3):485-492.
Published online January 1, 2001.
Nesidioblastosis in an Elderly Patient with Hyperinsulinemic Hypoglycemia.
Ye Kyung Seo, Jik Hwa Nam, Byung Ho Sin, Jung Guk Kim, Sung Woo Ha, Bo Whn Kim, Sang Won Jung, Young Guk Yun, In Su Seo, Chang Ho Cho
Nesidioblastosis is characterized by a diffuse proliferation of islet cells arising from pancreatic ducts and is the most common cause of hyperinsulinemic hypoglycemia in newborns and infantile. It is exceedingly rare in adults and no concensus regarding its diagnosis and management is available. We herein describe an elderly man with fasting hypoglycemia, inappropriate insulin hypersecretion. And pathologic examination of his pancreas revealed the characteristic finding of nesidioblastosis confirmed by immunohistochemical stain.
Key Words: Nesidioblastosis, Hyperinsulinemic hypoglycemia, mmunohistochemistry

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