Journal of Korean Endocrine Society 1997;12(4):584-588.
Published online January 1, 2001.
A Case of Partial Hypopituitarism after Recovery from Korean Hemorrhagic Fever.
Yeo Joo Kim, Mi Rim Kim, Moon Seok Nam, Yong Sung Kim, Sung Ki Kim, Sung Kwon Bae
Abstract
Heorrhage and infarct-like necrosis of anterior lobe of the pituitary gland is one of the characteristic pathologic findings of the autopsied cases of Korean Hemorrhagic Fever (KHF) patients, but there has been rare reports of hypopituitarism in patients with KHF. Recently we have experienced a patient with hyponatremia who had recovered from KHF. He was admitted to our hospital due to nausea, vomiting, and epigastric discornfort. To determine the function of the anterior pituitary gland, hormonal levels of target galnds and pituitary gland were measured, and combined pituitary stimulation test was performed. ACTH, GH, and prolactin deficiency were confirmed by combined pituitary stimulation test in this patient. There was no evidence of hypothalamic or other pituitary diseases by brain MRI. Our experience shows that KHF can be a cause of hypopituitarism and these findings should alert physicians the possibility of hypopituitarisrn in patients who had recovered from KHF.
Key Words: Partial hypopituitarism, Korean hemorrhagic fever


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