Journal of Korean Endocrine Society 1998;13(1):83-93.
Published online January 1, 2001.
Two Cases of Cushing's Disease Due to Large Pituitary ACTH Secreting Tumor.
Hong Seung Kim, Choon Hee Chung, Mee Yeon Cho, Young Goo Shin, Il Hoe Kim, Seok Woo Yang, Jang Young Kim
Cushing's syndrome that is caused by an adenoma of the corticotrape cells of the anterior pituitay or, rarely, by couticotrope hyperplasia is refered to as Cushing's disease. Cushings disease is usually characterized by chronic, moderate hypersecretion of ACTH and other POMC derived peptide. Most patients have ACTH-secreting anterior pituitary corticotrope microadenomas, but a small minority have a pituitary macroadenoma. We recently experenced two cases of Cushings disease due to pituitary macroadenoma. and report this cases with review of literatures.
Key Words: Cushing's disease, Macroadenoma

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