Journal of Korean Endocrine Society 1998;13(2):288-294.
Published online January 1, 2001.
A Case of Surgically Treated Insulinoma in Pregnancy.
Kwan Woo Lee, Euy Young Soh, Young Goo Shin, Sung Keun Lee, So Yun Park, Sung Kyu Lee, Yun Suk Chung, Hyun Man Kim, Kyung Joo Hwang, Yun Mi JIn
Insuliin secreting tumor is 70% prevalent disease in female and predoadnant in forth and sixth deeade. The incidence of insulinoma is one case per 250,000 patient-years. Insulinoma in pregnancy was extremely rare, and the prevalence was not reported. The diagnosis of an insulinoma is depend on demonstration of hypoglycemia with high insulin and C-peptide levels. Immunoreactive insulin/plasma glucose ratio0.3 in particular support the diagnosis of an insulinoma. Fetal complication would be developed because of hypoglycemia. In approximately half of the cases reported, surgical exploration was done during pregrancy, the remainder were treated after delivery. Insulinoma poses serious diagnostic and therapeutic problems when she is pregnant. We experienced a case of insulinoma in pregnancy that represented Whipples triad and was treated by surgical intervention.
Key Words: Insulinoma, Pregnancy, Surgical treatment

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