Endocrinology and Metabolism

Review Article

Calcium & Bone Metabolism

April 14, 2022

Discontinuing Denosumab: Can It Be Done Safely? A Review of the Literature

Wei Lin Tay, Donovan Tay

Endocrinol Metab. 2022;37(2):183-194.

Denosumab, which has been approved for the treatment of osteoporosis since 2010, is a fully humanised monoclonal antibody against a cytokine, receptor activator of nuclear factor kappa B ligand (RANKL),...

Review Article

Diabetes, Obesity and Metabolism

April 13, 2022

A Study on Methodologies of Drug Repositioning Using Biomedical Big Data: A Focus on Diabetes Mellitus

Suehyun Lee, Seongwoo Jeon, Hun-Sung Kim

Endocrinol Metab. 2022;37(2):195-207.

Drug repositioning is a strategy for identifying new applications of an existing drug that has been previously proven to be safe. Based on several examples of drug repositioning, we aimed...

Review Article

Thyroid

April 14, 2022

Thyroid Function across the Lifespan: Do Age-Related Changes Matter?

John P. Walsh

Endocrinol Metab. 2022;37(2):208-219.

Circulating concentrations of thyrotropin (TSH) and thyroxine (T4) are tightly regulated. Each individual has setpoints for TSH and free T4 which are genetically determined, and subject to environmental and epigenetic...

Original Article

Diabetes, Obesity and Metabolism

March 23, 2022

Stimulation of Alpha-1-Adrenergic Receptor Ameliorates Obesity-Induced Cataracts by Activating Glycolysis and Inhibiting Cataract-Inducing Factors

Yong-Jik Lee, Yoo-Na Jang, Hyun-Min Kim, et al.

Endocrinol Metab. 2022;37(2):221-232.

Background: Obesity, the prevalence of which is increasing due to the lack of exercise and increased consumption of Westernized diets, induces various complications, including ophthalmic diseases. For example, obesity is...

Original Article

Diabetes, Obesity and Metabolism

April 6, 2022

Comparative Study of Ex Vivo Antiplatelet Activity of Aspirin and Cilostazol in Patients with Diabetes and High Risk of Cardiovascular Disease

Sangmo Hong, Woo Je Lee, Cheol-Young Park

Endocrinol Metab. 2022;37(2):233-242.

Background: The role of aspirin in primary cardiovascular disease prevention in patients with diabetes remains controversial. However, some studies have suggested beneficial effects of cilostazol on cardiovascular disease in patients...

Original Article

Diabetes, Obesity and Metabolism

April 25, 2022

The Presence of Clonal Hematopoiesis Is Negatively Associated with Diabetic Peripheral Neuropathy in Type 2 Diabetes

Tae Jung Oh, Han Song, Youngil Koh, et al.

Endocrinol Metab. 2022;37(2):243-248.

Background: Clonal hematopoiesis of indeterminate potential (CHIP) has been reported to be associated with increased cardiovascular disease, aging and insulin resistance. Despite the debate of causal contribution of CHIP on...

Original Article

Diabetes, Obesity and Metabolism

April 7, 2022

Associations of Phthalate Metabolites and Bisphenol A Levels with Obesity in Children: The Korean National Environmental Health Survey (KoNEHS) 2015 to 2017

Moon Young Seo, Shinje Moon, Shin-Hye Kim, et al.

Endocrinol Metab. 2022;37(2):249-260.

Background: Phthalates and bisphenol A (BPA) are synthetic chemicals widely used in daily life. This study investigated urinary phthalate and BPA levels in Korean children and their associations with obesity....

Original Article

Diabetes, Obesity and Metabolism

April 25, 2022

Association of High-Density Lipoprotein Cholesterol Phenotypes with the Risk of Cardiovascular Diseases and Mortality: A Cohort Study in Korea

Ga Eun Nam, Youn Huh, Jin-Hyung Jung, et al.

Endocrinol Metab. 2022;37(2):261-271.

Background: We investigated whether low high-density lipoprotein cholesterol (HDL-C) and isolated and non-isolated low HDL-C levels are associated with the risk of cardiovascular diseases and all-cause mortality among Korean adults. Methods:...

Original Article

Diabetes, Obesity and Metabolism

April 13, 2022

Cumulative Exposure to High γ-Glutamyl Transferase Level and Risk of Diabetes: A Nationwide Population-Based Study

Ji-Yeon Park, Kyungdo Han, Hun-Sung Kim, et al.

Endocrinol Metab. 2022;37(2):272-280.

Background: Elevated γ-glutamyl transferase (γ-GTP) level is associated with metabolic syndrome, impaired glucose tolerance, and insulin resistance, which are risk factors for type 2 diabetes. We aimed to investigate the...

Original Article

Thyroid

April 6, 2022

Graves’ Disease and the Risk of End-Stage Renal Disease: A Korean Population-Based Study

Yoon Young Cho, Bongseong Kim, Dong Wook Shin, et al.

Endocrinol Metab. 2022;37(2):281-289.

Background: Hyperthyroidism is associated with an increased glomerular filtration rate (GFR) in the hyperdynamic state, which is reversible after restoring euthyroidism. However, long-term follow-up of renal dysfunction in patients with...

Original Article

Thyroid

April 8, 2022

Developmental Hypothyroidism Influences the Development of the Entorhinal-Dentate Gyrus Pathway of Rat Offspring

Ting Jin, Ranran Wang, Shiqiao Peng, et al.

Endocrinol Metab. 2022;37(2):290-302.

Background: Developmental hypothyroidism impairs learning and memory in offspring, which depend on extensive neuronal circuits in the entorhinal cortex, together with the hippocampus and neocortex. The entorhinal-dentate gyrus pathway is...

Original Article

Thyroid

April 6, 2022

Repeated Low High-Density Lipoprotein Cholesterol and the Risk of Thyroid Cancer: A Nationwide Population- Based Study in Korea

Jinyoung Kim, Mee Kyoung Kim, Ki-Hyun Baek, et al.

Endocrinol Metab. 2022;37(2):303-311.

Background: High-density lipoprotein cholesterol (HDL-C) plays an important role in the reverse cholesterol transport pathway and prevents atherosclerosis-mediated disease. It has also been suggested that HDL-C may be a protective...

Original Article

Thyroid

April 25, 2022

Immunoglobulin G4-Related Thyroid Disease: A Single-Center Experience and Literature Review

Meihua Jin, Bictdeun Kim, Ahreum Jang, et al.

Endocrinol Metab. 2022;37(2):312-322.

Background: Immunoglobulin G4 (IgG4)-related disease is an entity that can involve the thyroid gland. The spectrum of IgG4-related thyroid disease (IgG4-RTD) includes Hashimoto thyroiditis (HT) and its fibrotic variant, Riedel...

Original Article

Thyroid

April 13, 2022

Usefulness of Real-Time Quantitative Microvascular Ultrasonography for Differentiation of Graves’ Disease from Destructive Thyroiditis in Thyrotoxic Patients

Han-Sang Baek, Ji-Yeon Park, Chai-Ho Jeong, et al.

Endocrinol Metab. 2022;37(2):323-332.

Background: Microvascular ultrasonography (MVUS) is a third-generation Doppler technique that was developed to increase sensitivity compared to conventional Doppler. The purpose of this study was to compare MVUS with conventional...

Original Article

Calcium & Bone Metabolism

February 8, 2022

Association between Elevated Plasma Homocysteine and Low Skeletal Muscle Mass in Asymptomatic Adults

Jae-Hyeong Choi, Jin-Woo Seo, Mi-Yeon Lee, et al.

Endocrinol Metab. 2022;37(2):333-343.

Background: Homocysteine has been drawing attention with a closed linkage with skeletal muscle. However, the association of hyperhomocysteinemia with decreased skeletal muscle mass remains unclear. We aimed to investigate the...

Original Article

Calcium & Bone Metabolism

April 25, 2022

Effect of Vitamin D Supplementation on Risk of Fractures and Falls According to Dosage and Interval: A Meta-Analysis

Sung Hye Kong, Han Na Jang, Jung Hee Kim, et al.

Endocrinol Metab. 2022;37(2):344-358.

Background: Although recent studies comparing various dosages and intervals of vitamin D supplementation have been published, it is yet to be elucidated whether there is an appropriate dose or interval...

Original Article

Hypothalamus and Pituitary Gland

April 25, 2022

Metabolic Impacts of Discontinuation and Resumption of Recombinant Human Growth Hormone Treatment during the Transition Period in Patients with Childhood-Onset Growth Hormone Deficiency

Yun Jeong Lee, Yunha Choi, Han-Wook Yoo, et al.

Endocrinol Metab. 2022;37(2):359-368.

Background: Discontinuing growth hormone (GH) treatment during the transition to adulthood has been associated with adverse health outcomes in patients with childhood-onset growth hormone deficiency (CO-GHD). This study investigated the...

Original Article

Adrenal Gland

April 14, 2022

Outcome-Based Decision-Making Algorithm for Treating Patients with Primary Aldosteronism

Jung Hee Kim, Chang Ho Ahn, Su Jin Kim, et al.

Endocrinol Metab. 2022;37(2):369-382.

Background: Optimal management of primary aldosteronism (PA) is crucial due to the increased risk of cardiovascular and cerebrovascular diseases. Adrenal venous sampling (AVS) is the gold standard method for determining...

Current Issue: Volume 37(2); Apr 2022

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Endocrinology
and Metabolism

Print ISSN: 2093-596X
Online ISSN: 2093-5978

9,900	WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System
9,399	Sarcopenia and Muscle Aging: A Brief Overview
8,813	Encountering COVID-19 as Endocrinologists
7,554	Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma
7,296	Continuous Glucose Monitoring in the Hospital

Cited By 31	Impact of Skeletal Muscle Mass on Metabolic Health
Cited By 25	Prevalence and Current Management of Cardiovascular Risk Factors in Korean Adults Based on Fact Sheets
Cited By 22	Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis
Cited By 16	Visceral-to-Subcutaneous Abdominal Fat Ratio Is Associated with Nonalcoholic Fatty Liver Disease and Liver Fibrosis
Cited By 15	Sarcopenia and Muscle Aging: A Brief Overview

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