Endocrinology and Metabolism

Review Article

April 19, 2021

Sara Spinelli, Erminio Monteleone

Endocrinol Metab. 2021;36(2):209-219.

Obesity is a multifactorial disease with several potential causes that remain incompletely understood. Recent changes in the environment, which has become increasingly obesogenic, have been found to interact with individual...

Review Article

March 24, 2021

Digital Therapeutics for Obesity and Eating-Related Problems

Meelim Kim, Hyung Jin Choi

Endocrinol Metab. 2021;36(2):220-228.

In recent years, digital technologies have rapidly advanced and are being applied to remedy medical problems. These technologies allow us to monitor and manage our physical and mental health in...

Review Article

April 6, 2021

Dopaminergic Control of the Feeding Circuit

Ja-Hyun Baik

Endocrinol Metab. 2021;36(2):229-239.

There is increasing evidence demonstrating that reward-related motivational food intake is closely connected with the brain’s homeostatic system of energy balance and that this interaction might be important in the...

Review Article

March 31, 2021

Continuous Glucose Monitoring in the Hospital

M. Citlalli Perez-Guzman, Trisha Shang, Jennifer Y. Zhang, et al.

Endocrinol Metab. 2021;36(2):240-255.

Continuous glucose monitors (CGMs) have suddenly become part of routine care in many hospitals. The coronavirus disease 2019 (COVID-19) pandemic has necessitated the use of new technologies and new processes...

Review Article

April 19, 2021

Cardiorenal Protection in Diabetic Kidney Disease

Jason F. Lee, Ecaterina Berzan, Vikas S. Sridhar, et al.

Endocrinol Metab. 2021;36(2):256-269.

Over the last 5 years there have been many new developments in the management of diabetic kidney disease. Glucagon-like peptide-1 receptor agonists (GLP-1 RA) and sodium-glucose cotransporter-2 (SGLT2) inhibitors were...

Review Article

March 24, 2021

Operationalizing Treat-to-Target for Osteoporosis

E. Michael Lewiecki

Endocrinol Metab. 2021;36(2):270-278.

Treat-to-target (TTT) for osteoporosis is a concept for individualizing patient treatment decisions that focuses on achieving an acceptable level of fracture risk rather than response to treatment alone. While a...

Review Article

April 19, 2021

Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia

Brian Tomlinson, Nivritti Gajanan Patil, Manson Fok, et al.

Endocrinol Metab. 2021;36(2):279-295.

Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach low-density lipoprotein cholesterol (LDL-C) targets with...

Review Article

April 15, 2021

An Update on Contraception in Polycystic Ovary Syndrome

Seda Hanife Oguz, Bulent Okan Yildiz

Endocrinol Metab. 2021;36(2):296-311.

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged women, characterized by hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology. Combined oral contraceptives (COCs), along with lifestyle modifications, represent the...

Review Article

April 27, 2021

Clinical Characteristics, Management, and Potential Biomarkers of Endocrine Dysfunction Induced by Immune Checkpoint Inhibitors

Shintaro Iwama, Tomoko Kobayashi, Hiroshi Arima

Endocrinol Metab. 2021;36(2):312-321.

Original Article

Clinical Study

March 23, 2021

Associations of GNAS Mutations with Surgical Outcomes in Patients with Growth Hormone-Secreting Pituitary Adenoma

Hyein Jung, Kyungwon Kim, Daham Kim, et al.

Endocrinol Metab. 2021;36(2):342-350.

Background: The guanine nucleotide-binding protein, alpha stimulating (GNAS) gene has been associated with growth hormone (GH)-secreting pituitary adenoma. We investigated the prevalence of GNAS mutations in Korean patients with acromegaly...

Original Article

Clinical Study

April 6, 2021

Radioactive Parathyroid Adenomas on Sestamibi Scans: Low Parathyroid Hormone Secretory Potential and Large Volume

Sung Hye Kong, Jung Hee Kim, Sang Wan Kim, et al.

Endocrinol Metab. 2021;36(2):351-358.

Background: We investigated the clinical characteristics of parathyroid adenomas according to radioactivity on 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) single-photon emission computed tomography/computed tomography (SPECT/CT) in primary hyperparathyroidism (PHPT) patients. Methods: The study included 217...

Original Article

Clinical Study

March 23, 2021

Protocol for a Korean Multicenter Prospective Cohort Study of Active Surveillance or Surgery (KoMPASS) in Papillary Thyroid Microcarcinoma

Min Ji Jeon, Yea Eun Kang, Jae Hoon Moon, et al.

Endocrinol Metab. 2021;36(2):359-364.

Background: A Korean Multicenter Prospective cohort study of Active Surveillance or Surgery (KoMPASS) for papillary thyroid microcarcinomas (PTMCs) has been initiated. The aim is to compare clinical outcomes between active...

Original Article

Clinical Study

April 7, 2021

Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults

Eyun Song, Min Ji Jeon, Hye Jin Yoo, et al.

Endocrinol Metab. 2021;36(2):365-373.

Background: Serum calcitonin measurement contains various clinical and methodological aspects. Its reference level is wide and unclear despite sensitive calcitonin kits are available. This study aimed to identify the specific...

Original Article

Clinical Study

April 6, 2021

Efficacy and Safety of the Novel Dipeptidyl Peptidase-4 Inhibitor Gemigliptin in the Management of Type 2 Diabetes: A Meta-Analysis

Deep Dutta, Anshita Agarwal, Indira Maisnam, et al.

Endocrinol Metab. 2021;36(2):374-387.

Background: No meta-analysis has holistically analysed and summarised the efficacy and safety of gemigliptin in type 2 diabetes. The meta-analysis addresses this knowledge gap. Methods: Electronic databases were searched for randomised...

Original Article

Clinical Study

March 31, 2021

Comparative Renal Effects of Dipeptidyl Peptidase-4 Inhibitors and Sodium-Glucose Cotransporter 2 Inhibitors on Individual Outcomes in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis

Jae Hyun Bae, Eun-Gee Park, Sunhee Kim, et al.

Endocrinol Metab. 2021;36(2):388-400.

Background: To compare the renal effects of dipeptidyl peptidase-4 (DPP-4) inhibitors and sodium-glucose cotransporter 2 (SGLT2) inhibitors on individual outcomes in patients with type 2 diabetes. Methods: We searched electronic databases...

Original Article

Clinical Study

March 31, 2021

Diagnostic Accuracy of Computed Tomography in Predicting Primary Aldosteronism Subtype According to Age

Seung Hun Lee, Jong Woo Kim, Hyun-Ki Yoon, et al.

Endocrinol Metab. 2021;36(2):401-412.

Background: Guidelines by the Endocrine Society Guideline on bypassing adrenal vein sampling (AVS) in patients

Original Article

Clinical Study

April 6, 2021

Characteristics of Immune-Related Thyroid Adverse Events in Patients Treated with PD-1/PD-L1 Inhibitors

Jee Hee Yoon, A Ram Hong, Hee Kyung Kim, et al.

Endocrinol Metab. 2021;36(2):413-423.

Background: Thyroid immune-related adverse events (IRAEs) have been reported in patients treated with programmed cell death protein-1 (PD-1) and programmed cell death protein-ligand 1 (PD-L1) inhibitors. We investigated the incidence...

Original Article

Clinical Study

April 14, 2021

Cumulative Exposure to Metabolic Syndrome Components and the Risk of Dementia: A Nationwide Population-Based Study

Yunjung Cho, Kyungdo Han, Da Hye Kim, et al.

Endocrinol Metab. 2021;36(2):424-435.

Background: Metabolic disturbances are modifiable risk factors for dementia. Because the status of metabolic syndrome (MetS) and its components changes over time, we aimed to investigate the association of the...

Original Article

Clinical Study

April 19, 2021

High Serum-Induced AhRL Is Associated with Prevalent Metabolic Syndrome and Future Impairment of Glucose Tolerance in the Elderly

Youngmi Kim Pak, Hoon Sung Choi, Wook Ha Park, et al.

Endocrinol Metab. 2021;36(2):436-446.

Background: High circulating levels of dioxins and dioxin-like chemicals, acting via the aryl hydrocarbon receptor (AhR), have previously been linked to diabetes. We now investigated whether the serum AhR ligands...

Original Article

Endocrine Research

March 31, 2021

DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption

Min Joo Kim, Hwan Hee Kim, Young Shin Song, et al.

Endocrinol Metab. 2021;36(2):447-454.

Background: Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on...

Original Article

Endocrine Research

April 14, 2021

Effect of CCL11 on In Vitro Myogenesis and Its Clinical Relevance for Sarcopenia in Older Adults

Da Ae Kim, So Jeong Park, Jin Young Lee, et al.

Endocrinol Metab. 2021;36(2):455-465.

Background: The C-C motif chemokine ligand 11 (CCL11) has been receiving attention as a potential pro-aging factor. Accordingly, it may be involved in muscle metabolism and sarcopenia, a key component...

Current Issue: Volume 36(2); Apr 2021

Endocrinology
and Metabolism

Print ISSN: 2093-596X
Online ISSN: 2093-5978

4,393	Tumor Cells and Cancer-Associated Fibroblasts: A Synergistic Crosstalk to Promote Thyroid Cancer
4,610	WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System
2,951	Association of Vitamin D Deficiency with Diabetic Nephropathy
2,823	Sarcopenia and Muscle Aging: A Brief Overview
1,910	In Vivo and In Vitro Quantification of Glucose Kinetics: From Bedside to Bench

Cited By 26	Long-Term Outcomes Following Thermal Ablation of Benign Thyroid Nodules as an Alternative to Surgery: The Importance of Controlling Regrowth
Cited By 21	Graves' Disease: Can It Be Cured?
Cited By 17	Triglyceride Glucose Index Is Superior to the Homeostasis Model Assessment of Insulin Resistance for Predicting Nonalcoholic Fatty Liver Disease in Korean Adults
Cited By 17	Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective
Cited By 16	Recent Progress on Branched-Chain Amino Acids in Obesity, Diabetes, and Beyond