Variation in the gross anatomy of the thyroid is relatively common. Although thyroid hemiagenesis is considered to be a rare congenital anomaly, its incidence is probably underestimated because the diagnosis is usually incidental.We present the case of a 26-year-old woman with right thyroid hemiagenesis associated with papillary adenocarcinoma. The diagnosis of hemiagenesis was established by isotope imaging, which showed hot nodule, thyroid ultrasonography and surgical exploration for proper management of a nodule in the left lobe of thyroid gland. As she was diagnosed to have papillary adenocarcinoma, total thyroidectomy was performed and at present she remains disease-free.
Thyroid hemiagenesis is a rare congenital anomaly, in which one thyroid lobe fails to develop. Thyroid hemiagenesis is associated with thyroid diseases such as Graves' disease, Hashimoto's thyroiditis, colloidal goiter and thyroid follicular and papillary cancer. A 53-year-old female patient was diagnosed with a thyroid nodule on health examination. A 99mTc pertechnetate thyroid scan showed absent uptake in the left lobe and cold nodule on the right lobe of thyroid gland. By ultrasonography, we found hemiagenesis in the left thyroid gland and an irregular shaped thyroid nodule on the right lobe of thyroid gland. We performed ultrasonography guided fine needle aspiration and cytologic analysis showed indeterminate nature. Thyroidectomy was performed and finally diagnosed follicular carcinoma of thyroid gland. The authors report this case with a literature review.
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A Case of Thyroid Hemiagenesis with Concurrent Papillary Thyroid Carcinoma Ye-Mo Nam, June Sik Park, Kyung Jin Na, Dongbin Ahn Korean Journal of Otorhinolaryngology-Head and Neck Surgery.2011; 54(8): 557. CrossRef