Skip Navigation
Skip to contents

Endocrinol Metab : Endocrinology and Metabolism

clarivate
OPEN ACCESS
SEARCH
Search

Search

Page Path
HOME > Search
2 "Specificity"
Filter
Filter
Article type
Keywords
Publication year
Authors
Review Article
Obesity and Metabolism
Optimal Waist Circumference Cutoff Values for the Diagnosis of Abdominal Obesity in Korean Adults
Yeong Sook Yoon, Sang Woo Oh
Endocrinol Metab. 2014;29(4):418-426.   Published online December 29, 2014
DOI: https://doi.org/10.3803/EnM.2014.29.4.418
  • 7,302 View
  • 71 Download
  • 67 Web of Science
  • 72 Crossref
AbstractAbstract PDFPubReader   

Abdominal obesity is associated closely with insulin resistance, diabetes, and cardiovascular disease. Waist circumference (WC) is a useful surrogate marker commonly used for abdominal adiposity. The determination of WC cutoff levels is important in the prevention and treatment of obesity, type 2 diabetes, and related cardiovascular diseases. Recent epidemiological evidence suggested that appropriate optimal cutoffs for Koreans ranged over 80 to 89.8 cm in males and 76.1 to 86.5 cm in females. We analyzed the data from two large cohorts using receiver operating characteristic curve analysis with the incidences of diabetes, hypertension, dyslipidemia, cerebrovascular disease, myocardial infarct, angina, coronary artery disease, and multiple metabolic risk factors as outcome variables. Optimal WC cutoff points for Koreans were 85 cm in males and 80 cm in females. However, considering the prevalence of abdominal obesity and the health costs for its prevention and management, 90 cm in males and 85 cm in females are probably more appropriate thresholds for abdominal obesity. These values may be modified once better research is performed through prospective studies using representative populations, common health outcomes, and proper analytical approaches.

Citations

Citations to this article as recorded by  
  • Machine learning analysis for the association between breast feeding and metabolic syndrome in women
    Jue Seong Lee, Eun-Saem Choi, Hwasun Lee, Serhim Son, Kwang-Sig Lee, Ki Hoon Ahn
    Scientific Reports.2024;[Epub]     CrossRef
  • Association between waist circumference change after smoking cessation and incidence of hypertension in Korean adults
    H.J. Lee, J.W. Choi
    Public Health.2024; 229: 73.     CrossRef
  • Surrogate indices of insulin resistance using the Matsuda index as reference in adult men—a computational approach
    Víctor Antonio Malagón-Soriano, Andres Julian Ledezma-Forero, Cristian Felipe Espinel-Pachon, Álvaro Javier Burgos-Cárdenas, Maria Fernanda Garces, Gustavo Eduardo Ortega-Ramírez, Roberto Franco-Vega, Jhon Jairo Peralta-Franco, Luis Miguel Maldonado-Acost
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • The positive impact of smoking cessation on fracture risk in a nationwide cohort study
    Jin-Sung Park, Kyung-Chung Kang, Se-Jun Park, Jeong-Keun Kim, Kyungdo Han, Jae-Young Hong
    Scientific Reports.2024;[Epub]     CrossRef
  • Waist circumference and end‐stage renal disease based on glycaemic status: National Health Insurance Service data 2009–2018
    Yun Kyung Cho, Ji Hye Huh, Shinje Moon, Yoon Jung Kim, Yang‐Hyun Kim, Kyung‐do Han, Jun Goo Kang, Seong Jin Lee, Sung‐Hee Ihm
    Journal of Cachexia, Sarcopenia and Muscle.2023; 14(1): 585.     CrossRef
  • Simple anthropometric measures to predict visceral adipose tissue area in middle-aged Indonesian men
    Sahat Basana Romanti Ezer Matondang, Bennadi Adiandrian, Komang Shary Karismaputri, Cicilia Marcella, Joedo Prihartono, Dicky Levenus Tahapary, Yosuke Yamada
    PLOS ONE.2023; 18(1): e0280033.     CrossRef
  • Sleep Quality in Women with Premenstrual Syndrome Is Associated with Metabolic Syndrome-Related Variables
    Hyejin Chun, Miae Doo
    Healthcare.2023; 11(10): 1492.     CrossRef
  • Gender, Age and Clinical Characteristics of Older Adults with High-Risk of Obstructive Sleep Apnea Assessed by the STOP-Bang Questionnaire
    Gyu Lee Kim, Yun Jin Kim, Jeong Gyu Lee, Yu Hyeon Yi, Young Jin Tak, Seung Hun Lee, Young Jin Ra, Sang Yeoup Lee, Young Hye Cho, Eun Ju Park, Youngin Lee, Jung In Choi, Sae Rom Lee, Ryuk Jun Kwon, Soo Min Son
    Korean Journal of Clinical Geriatrics.2023; 24(2): 72.     CrossRef
  • Body Composition and Cardiovascular Risk: A Study of Polish Military Flying Personnel
    Agata Gaździńska, Stefan Gaździński, Paweł Jagielski, Paweł Kler
    Metabolites.2023; 13(10): 1102.     CrossRef
  • The prevalence and factors associated with sarcopenia in Thai older adults: A systematic review and meta-analysis
    Phatcharaphon Whaikid, Noppawan Piaseu
    International Journal of Nursing Sciences.2023;[Epub]     CrossRef
  • Associated Factors with Changes of Metabolic Abnormalities among General Population in COVID-19 Pandemic
    Eunjoo Kwon, Eun-Hee Nah, Suyoung Kim, Seon Cho, Hyeran Park
    Korean Journal of Health Promotion.2023; 23(2): 55.     CrossRef
  • Effects of Pharmacoacupuncture for Obesity: A Systematic Review and Meta-Analysis
    Seyun Kim, Mi-Yeon Song, Won-Seok Chung, Hyungsuk Kim, Woo-Chul Shin, Junhyuk Kang, Joonwon Seo, Sangwoo Seo, Seung Ho Yu, Jung-Hyun Lim, Su-Hwan Ji, Jae-Heung Cho
    Journal of Korean Medicine for Obesity Research.2023; 23(2): 112.     CrossRef
  • Associations Between Elevated Growth Differentiation Factor-15 and Sarcopenia Among Community-dwelling Older Adults
    Miji Kim, Jeremy D Walston, Chang Won Won, Anne B Newman
    The Journals of Gerontology: Series A.2022; 77(4): 770.     CrossRef
  • The association of obesity with thyroid carcinoma risk
    Xiao‐Ni Ma, Cheng‐Xu Ma, Li‐Jie Hou, Song‐Bo Fu
    Cancer Medicine.2022; 11(4): 1136.     CrossRef
  • A Longitudinal Retrospective Observational Study on Obesity Indicators and the Risk of Impaired Fasting Glucose in Pre- and Postmenopausal Women
    Myung Ji Nam, Hyunjin Kim, Yeon Joo Choi, Kyung-Hwan Cho, Seon Mee Kim, Yong-Kyun Roh, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Joo-Hyun Park, Do-Hoon Kim
    Journal of Clinical Medicine.2022; 11(10): 2795.     CrossRef
  • Association of Metabolic Health and Central Obesity with the Risk of Thyroid Cancer: Data from the Korean Genome and Epidemiology Study
    Dung N. Nguyen, Jin Hee Kim, Mi Kyung Kim
    Cancer Epidemiology, Biomarkers & Prevention.2022; 31(3): 543.     CrossRef
  • Interaction of polygenic variants specific for abdominal obesity risk with energy metabolism in large Korean cohorts
    Sunmin Park
    Nutrition Bulletin.2022; 47(3): 307.     CrossRef
  • Effects of Oral Health Behavior and Mental Health on Metabolic Syndrome in Korean Adults
    Jin-Ah Jung, Hye-Won Cheon, Sang-Eun Moon, Sun-Hwa Hong
    Journal of Dental Hygiene Science.2022; 22(2): 90.     CrossRef
  • Relation of Dietary n-3 and n-6 Fatty Acid Intakes to Metabolic Syndrome in Middle-Aged People Depending on the Level of HbA1c: A Review of National Health and Nutrition Survey Data from 2014 to 2016
    Seo-Woo Park, Do-Yeong Kim, Gyeong-Tae Bak, Dae-Sung Hyun, Sung-Kyung Kim
    Medicina.2022; 58(8): 1017.     CrossRef
  • Synergistic Interaction between Hyperuricemia and Abdominal Obesity as a Risk Factor for Metabolic Syndrome Components in Korean Population
    Min Jin Lee, Ah Reum Khang, Yang Ho Kang, Mi Sook Yun, Dongwon Yi
    Diabetes & Metabolism Journal.2022; 46(5): 756.     CrossRef
  • Risk of Carotid Atherosclerosis in Subjects with Prediabetes Overlapping Metabolic Syndrome
    Seol A Jang, Kyoung Min Kim, Seok Won Park, Chul Sik Kim
    Metabolic Syndrome and Related Disorders.2022; 20(10): 599.     CrossRef
  • Association of high body mass index, waist circumference, and body fat percentage with sarcopenia in older women
    Myung Chul Yoo, Chang Won Won, Yunsoo Soh
    BMC Geriatrics.2022;[Epub]     CrossRef
  • Relationship between low skeletal muscle mass, sarcopenic obesity and left ventricular diastolic dysfunction in Korean adults
    Jee Hee Yoo, Sung Woon Park, Ji Eun Jun, Sang‐Man Jin, Kyu Yeon Hur, Moon‐Kyu Lee, Mira Kang, Gyuri Kim, Jae Hyeon Kim
    Diabetes/Metabolism Research and Reviews.2021;[Epub]     CrossRef
  • Association of Early-Life Mental Health With Biomarkers in Midlife and Premature Mortality
    George B. Ploubidis, G. David Batty, Praveetha Patalay, David Bann, Alissa Goodman
    JAMA Psychiatry.2021; 78(1): 38.     CrossRef
  • A clinical evaluation of noninvasive and contactless radiofrequency technique in the treatment of abdominal fat
    Jie Qin, Meng‐er Guo, Xue‐gang Xu, Chao Zhang, Cheng‐qian Yu, Yuan‐hong Li, Hong‐duo Chen
    Journal of Cosmetic Dermatology.2021; 20(9): 2765.     CrossRef
  • Exercise training and burdock root (Arctium lappa L.) extract independently improve abdominal obesity and sex hormones in elderly women with metabolic syndrome
    Min-Seong Ha, Jang Soo Yook, Minchul Lee, Kazuya Suwabe, Woo-Min Jeong, Jae-Jun Kwak, Hideaki Soya
    Scientific Reports.2021;[Epub]     CrossRef
  • Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study
    Woo-Hyuk Song, Eun Hui Bae, Jeong Cheon Ahn, Tae Ryom Oh, Yong-Hyun Kim, Jin Seok Kim, Sun-Won Kim, Soo Wan Kim, Kyung-Do Han, Sang-Yup Lim
    The Korean Journal of Internal Medicine.2021; 36(Suppl 1): S90.     CrossRef
  • Individual and Synergistic Relationships of Low Muscle Mass and Low Muscle Function with Depressive Symptoms in Korean Older Adults
    Youngyun Jin, Seamon Kang, Hyunsik Kang
    International Journal of Environmental Research and Public Health.2021; 18(19): 10129.     CrossRef
  • Association between Metabolic Syndrome and the Number of Remaining Teeth in Postmenopausal Women: A Cross-Sectional Analysis Using the Korean National Health and Nutritional Examination Survey
    Jeong-In Kim, Choong-Ho Choi, Ki-Ho Chung
    Journal of Clinical Medicine.2021; 10(20): 4759.     CrossRef
  • No Association between Metabolic Syndrome and Periodontitis in Korean Postmenopausal Women
    Jeong-In Kim, Choong-Ho Choi, Ki-Ho Chung
    International Journal of Environmental Research and Public Health.2021; 18(21): 11110.     CrossRef
  • Relative Lean Body Mass and Waist Circumference for the Identification of Metabolic Syndrome in the Korean General Population
    Eunjoo Kwon, Eun-Hee Nah, Suyoung Kim, Seon Cho
    International Journal of Environmental Research and Public Health.2021; 18(24): 13186.     CrossRef
  • SVM-based waist circumference estimation using Kinect
    Dasom Seo, Euncheol Kang, Yu-mi Kim, Sun-Young Kim, Il-Seok Oh, Min-Gul Kim
    Computer Methods and Programs in Biomedicine.2020; 191: 105418.     CrossRef
  • Effects of abdominal obesity on the association between air pollution and kidney function
    Su-Min Jeong, Jin-Ho Park, Hyun-Jin Kim, Hyuktae Kwon, Seo Eun Hwang
    International Journal of Obesity.2020; 44(7): 1568.     CrossRef
  • Effect of sarcopenic obesity on deterioration of physical function in the elderly
    Hyun Ho Kong, Chang Won Won, Won Kim
    Archives of Gerontology and Geriatrics.2020; 89: 104065.     CrossRef
  • Effects of low skeletal muscle mass and sarcopenic obesity on albuminuria: a 7-year longitudinal study
    Jee Hee Yoo, Gyuri Kim, Sung Woon Park, Min Sun Choi, Jiyeon Ahn, Sang-Man Jin, Kyu Yeon Hur, Moon-Kyu Lee, Mira Kang, Jae Hyeon Kim
    Scientific Reports.2020;[Epub]     CrossRef
  • A Novel Indicator of Children’s Lipid Accumulation Product Associated with Impaired Fasting Glucose in Chinese Children and Adolescents


    Yongting Yuan, Hong Xie, Lili Sun, Bangxuan Wang, Li Zhang, Hui Han, Rongying Yao, Yehuan Sun, Lianguo Fu
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 1653.     CrossRef
  • The Association between the Ratio of Energy Intake to Basal Metabolic Rate and Physical Activity to Sarcopenia: Using the Korea National Health and Nutrition Examination Surveys (2008–2011)
    Yu Jin Cho, Mi Hee Cho, Bomi Han, Minji Park, Seolah Bak, Minseon Park
    Korean Journal of Family Medicine.2020; 41(3): 167.     CrossRef
  • Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity
    Robert Ross, Ian J. Neeland, Shizuya Yamashita, Iris Shai, Jaap Seidell, Paolo Magni, Raul D. Santos, Benoit Arsenault, Ada Cuevas, Frank B. Hu, Bruce A. Griffin, Alberto Zambon, Philip Barter, Jean-Charles Fruchart, Robert H. Eckel, Yuji Matsuzawa, Jean-
    Nature Reviews Endocrinology.2020; 16(3): 177.     CrossRef
  • Lung function as a predictor of incident type 2 diabetes in community-dwelling adults: A longitudinal finding over 12 years from the Korean Genome and Epidemiology Study
    J.H. Lee, H.S. Lee, Y.J. Lee
    Diabetes & Metabolism.2020; 46(5): 392.     CrossRef
  • Sex- and age-specific effects of energy intake and physical activity on sarcopenia
    Yu Jin Cho, Youn-Hee Lim, Jae Moon Yun, Hyung-Jin Yoon, Minseon Park
    Scientific Reports.2020;[Epub]     CrossRef
  • Protective effect of smoking cessation on subsequent myocardial infarction and ischemic stroke independent of weight gain: A nationwide cohort study
    Jung-Hwan Cho, Hye-Mi Kwon, Se-Eun Park, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Yang-Hyun Kim, Eun-Jung Rhee, Won-Young Lee, Michael Cummings
    PLOS ONE.2020; 15(7): e0235276.     CrossRef
  • Optimal Cutoff Values for Anthropometric Adiposity Measures of Sri Lankan Adult Women
    Nirmala Rathnayake, Gayani Alwis, Janaka Lenora, Sarath Lekamwasam
    Journal of Obesity.2020; 2020: 1.     CrossRef
  • Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study


    Hyejin Chun, Gi Dae Kim, Miae Doo
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 3601.     CrossRef
  • Patterns of change in cardiovascular risks of Korean male workers: a 10-year cohort analysis using the National Health Insurance Service–National Sample Cohort (NHIS-NSC) 2.0 database
    Hosihn Ryu, Jiyeon Jung, Jihyun Moon
    BMJ Open.2020; 10(11): e038446.     CrossRef
  • Predictive Performance of Glycated Hemoglobin for Incident Diabetes Compared with Glucose Tolerance Test According to Central Obesity
    Suji Yoo, Jaehoon Jung, Hosu Kim, Kyoung Young Kim, Soo Kyoung Kim, Jungwha Jung, Jong Ryeal Hahm, Jong Ha Baek
    Endocrinology and Metabolism.2020; 35(4): 873.     CrossRef
  • Metabolic Syndrome and Risk of Lung Cancer: An Analysis of Korean National Health Insurance Corporation Database
    Sooim Sin, Chang-Hoon Lee, Sun Mi Choi, Kyung-Do Han, Jinwoo Lee
    The Journal of Clinical Endocrinology & Metabolism.2020; 105(11): e4102.     CrossRef
  • Association of body mass index with bladder cancer risk in men depends on abdominal obesity
    Jin Bong Choi, Jung Ho Kim, Sung-Hoo Hong, Kyung-Do Han, U-Syn Ha
    World Journal of Urology.2019; 37(11): 2393.     CrossRef
  • Lower Leg Fat Depots Are Associated with Albuminuria Independently of Obesity, Insulin Resistance, and Metabolic Syndrome (Korea National Health and Nutrition Examination Surveys 2008 to 2011)
    Eugene Han, Nan Hee Cho, Mi Kyung Kim, Hye Soon Kim
    Diabetes & Metabolism Journal.2019; 43(4): 461.     CrossRef
  • The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study
    Jung-Hwan Cho, Eun-Jung Rhee, Se-Eun Park, Hyemi Kwon, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Hye Soon Park, Yang-Hyun Kim, Soon-Jib Yoo, Won-Young Lee
    Diabetes & Metabolism Journal.2019; 43(2): 206.     CrossRef
  • Association between Serum Gamma-Glutamyltransferase and Prevalence of Metabolic Syndrome Using Data from the Korean Genome and Epidemiology Study
    Mi Young Lee, Dae Sung Hyon, Ji Hye Huh, Hae Kyung Kim, Sul Ki Han, Jang Young Kim, Sang Baek Koh
    Endocrinology and Metabolism.2019; 34(4): 390.     CrossRef
  • The Association between Obesity Phenotypes and Early Renal Function Decline in Adults without Hypertension, Dyslipidemia, and Diabetes
    Jung In Choi, Young Hye Cho, Sang Yeoup Lee, Dong Wook Jeong, Jeong Gyu Lee, Yu Hyeon Yi, Young Jin Tak, Seung Hun Lee, Hye Rim Hwang, Eun Ju Park
    Korean Journal of Family Medicine.2019; 40(3): 176.     CrossRef
  • Sex differences in the association between asthma incidence and modifiable risk factors in Korean middle-aged and older adults: NHIS-HEALS 10-year cohort
    Susan Park, Sun-Young Jung, Jin-Won Kwon
    BMC Pulmonary Medicine.2019;[Epub]     CrossRef
  • Plasma sphingomyelins increase in pre-diabetic Korean men with abdominal obesity
    Seung-Soon Im, Hyeon Young Park, Jong Cheol Shon, In-Sung Chung, Ho Chan Cho, Kwang-Hyeon Liu, Dae-Kyu Song, Kyoung Heon Kim
    PLOS ONE.2019; 14(3): e0213285.     CrossRef
  • Estimating the Cutoff Points of Time-Dependent Risk Factors by Using Joint Modeling of Longitudinal and Time-to-Event Data: A 14-Year Follow-up Study—Tehran Lipid and Glucose Study
    Nezhat Shakeri, Fereidoun Azizi
    Asia Pacific Journal of Public Health.2019; 31(8): 728.     CrossRef
  • Metabolic Obesity Phenotypes and Thyroid Cancer Risk: A Cohort Study
    Hyemi Kwon, Yoosoo Chang, Ara Cho, Jiin Ahn, Se Eun Park, Cheol-Young Park, Won-Young Lee, Ki-Won Oh, Sung-Woo Park, Hocheol Shin, Seungho Ryu, Eun-Jung Rhee
    Thyroid.2019; 29(3): 349.     CrossRef
  • Trends and Cut-Point Changes in Obesity Parameters by Age Groups Considering Metabolic Syndrome
    Hyung Jun Park, Young Ho Hong, Yun Jung Cho, Ji Eun Lee, Jae Moon Yun, Hyuktae Kwon, Sang Hyuck Kim
    Journal of Korean Medical Science.2018;[Epub]     CrossRef
  • Difference in prostate cancer incidence around sixty years: effects of age and metabolic diseases
    Jin Bong Choi, Jung Ho Kim, Sung‐Hoo Hong, Kyung‐Do Han, U‐Syn Ha
    Cancer Medicine.2018; 7(6): 2736.     CrossRef
  • The Association of Low Back Pain with Obesity and Abdominal Obesity among Koreans Aged 50 Years or More
    Eun Young Choi
    Korean Journal of Health Promotion.2018; 18(3): 119.     CrossRef
  • Association between oral health and colorectal adenoma in a screening population
    Donghyoun Lee, Kyung Uk Jung, Hyung Ook Kim, Hungdai Kim, Ho-Kyung Chun
    Medicine.2018; 97(37): e12244.     CrossRef
  • An association of metabolic syndrome and chronic kidney disease from a 10-year prospective cohort study
    Ji Hye Huh, Dhananjay Yadav, Jae Seok Kim, Jung-Woo Son, Eunhee Choi, Seong Hwan Kim, Chol Shin, Ki-Chul Sung, Jang Young Kim
    Metabolism.2017; 67: 54.     CrossRef
  • Anatomic fat depots and cardiovascular risk: a focus on the leg fat using nationwide surveys (KNHANES 2008–2011)
    Eugene Han, Yong-ho Lee, Byung-Wan Lee, Eun Seok Kang, In-Kyu Lee, Bong-Soo Cha
    Cardiovascular Diabetology.2017;[Epub]     CrossRef
  • Association between Body Weight Changes and Menstrual Irregularity: The Korea National Health and Nutrition Examination Survey 2010 to 2012
    Kyung Min Ko, Kyungdo Han, Youn Jee Chung, Kun-Ho Yoon, Yong Gyu Park, Seung-Hwan Lee
    Endocrinology and Metabolism.2017; 32(2): 248.     CrossRef
  • Low muscle mass and risk of type 2 diabetes in middle-aged and older adults: findings from the KoGES
    Jang Won Son, Seong Su Lee, Sung Rae Kim, Soon Jib Yoo, Bong Yun Cha, Ho Young Son, Nam H. Cho
    Diabetologia.2017; 60(5): 865.     CrossRef
  • Safety and efficacy of a non-contact radiofrequency device for body contouring in Asians
    Dong Hye Suh, Chang Min Kim, Sang Jun Lee, Hyunjoo Kim, Suk Keu Yeom, Hwa Jung Ryu
    Journal of Cosmetic and Laser Therapy.2017; 19(2): 89.     CrossRef
  • Arterial stiffness and its association with clustering of metabolic syndrome risk factors
    Wanda R. P. Lopes-Vicente, Sara Rodrigues, Felipe X. Cepeda, Camila Paixão Jordão, Valéria Costa-Hong, Akothirene C. B. Dutra-Marques, Jefferson C. Carvalho, Maria Janieire N. N. Alves, Luiz A. Bortolotto, Ivani C. Trombetta
    Diabetology & Metabolic Syndrome.2017;[Epub]     CrossRef
  • Associations of sitting time and occupation with metabolic syndrome in South Korean adults: a cross-sectional study
    Jin Young Nam, Juyoung Kim, Kyung Hee Cho, Young Choi, Jaewoo Choi, Jaeyong Shin, Eun-Cheol Park
    BMC Public Health.2016;[Epub]     CrossRef
  • Associations of Obesity and Dyslipidemia with Intake of Sodium, Fat, and Sugar among Koreans: a Qualitative Systematic Review
    Yoon Jung Kang, Hye Won Wang, Se Young Cheon, Hwa Jung Lee, Kyung Mi Hwang, Hae Seong Yoon
    Clinical Nutrition Research.2016; 5(4): 290.     CrossRef
  • Articles in 'Endocrinology and Metabolism' in 2014
    Won-Young Lee
    Endocrinology and Metabolism.2015; 30(1): 47.     CrossRef
  • Ambient Temperature and Prevalence of Obesity: A Nationwide Population-Based Study in Korea
    Hae Kyung Yang, Kyungdo Han, Jae-Hyoung Cho, Kun-Ho Yoon, Bong-Yun Cha, Seung-Hwan Lee, David Meyre
    PLOS ONE.2015; 10(11): e0141724.     CrossRef
  • Acupoint Catgut Embedding for Obesity: Systematic Review and Meta-Analysis
    Taipin Guo, Yulan Ren, Jun Kou, Jing Shi, Sun Tianxiao, Fanrong Liang
    Evidence-Based Complementary and Alternative Medicine.2015; 2015: 1.     CrossRef
  • Elderly men over 65 years of age with late-onset hypogonadism benefit as much from testosterone treatment as do younger men
    Farid Saad, Aksam Yassin, Ahmad Haider, Gheorghe Doros, Louis Gooren
    Korean Journal of Urology.2015; 56(4): 310.     CrossRef
  • Administration of Hwang-Ryun-Haedok-tang, a Herbal Complex, for Patients With Abdominal Obesity: A Case Series
    Seungwon Kwon, WooSang Jung, A Ri Byun, SangKwan Moon, KiHo Cho, KyoungHo Shin
    EXPLORE.2015; 11(5): 401.     CrossRef
Close layer
Evaluation Studies
Diagnostic Value of 24-hours Urinary Total Metanephrine As a Screening Test of Patients with Suspected Pheochromocytoma.
Sang Wan Kim, Kyung Won Kim, Do Joon Park, Chan Soo Shin, Kyung Soo Park, Seong Yeon Kim, Bo Youn Cho, Hong Kyu Lee
J Korean Endocr Soc. 2005;20(1):12-20.   Published online February 1, 2005
DOI: https://doi.org/10.3803/jkes.2005.20.1.12
  • 1,608 View
  • 22 Download
AbstractAbstract PDF
BACKGROUND
A pheochromocytoma is a rare cause of secondary hypertension. Its diagnosis is important as the hypertension is usually curable by resection of the tumor, whereas the condition is potentially lethal if undetected. Biochemical confirmation of excessive catecholamine production is a prerequisite to a definitive diagnosis. Various studies from other countries have indicated that measuring of the urinary metanephrine, using a specific procedure, is the single most reliable screening test for all patients suspected of having a pheochromocytoma. However, the diagnostic value of urinary metanephrine has never been reported in Korea. We investigated the diagnostic value of 24-hours urinary metanephrine in patients with a suspected pheochromocytoma. METHODS: This was a retrospective evaluation study, which included 95 patients with sustained hypertension and paroxysmal symptoms, and 38 patients with asymptomatic adrenal incidentaloma at Seoul National University Hospital, between July 2000 and October 2002. We performed the 24- hour urinary total metanephrine test on all patients. The diagnosis of a pheochromocytoma was applied only when confirmed by pathological analysis of a resected specimen. The possibility of a pheochromocytoma was ruled out when all biochemical tests were normal, which were performed at least in duplicate, or there was no evidence of a mass in abdominal radiological studies or histological verification. We determined the upper reference limit for urinary metanephrine as 1.3mg/day and calculated the sensitivity and specificity of the 24-hour urinary metanephrine test. RESULTS: Seventeen patients were diagnosed with a pheochromocytoma. The total metanephrine measurement had sensitivities and specificities of 82.4 and 73.3% in all the patients, 90.9 and 66.7% in patients with hypertension and paroxysmal symptoms, and 66.7 and 90.6% in patients with adrenal incidentaloma, respectively. CONCLUSION: The urinary total metanephrine measurement had relatively lower sensitivities and specificities than in other countries(sensitivity: 83~100%, specificity: 80~98%). The sensitivity of urinary metanephrine was relatively high in patients with hypertension and paroxysmal symptoms, and the specificity was high in patients with an adrenal incidentaloma. We suggest that normetanephrine and metanephrine should be separately measured, and a reasonable upper reference limit be used. It may also be necessary to measure urinary metanephrine together with urinary catecholamine or VMA to improve the diagnostic value of the urinary metanephrine test.
Close layer

Endocrinol Metab : Endocrinology and Metabolism
TOP