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1 "Gonadotropin-releasing hormone agonist"
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Case Report
Thyroid Dysfunction Associated with Administration of the Long-Acting Gonadotropin-Releasing Hormone Agonist
Eun Jin Han, Ha Do Song, Ji Hoon Yang, So Young Park, Sung Hoon Kim, Hyun Koo Yoon, Chang Hoon Yim
Endocrinol Metab. 2013;28(3):221-225.   Published online September 13, 2013
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AbstractAbstract PDFPubReader   

Gonadotropin-releasing hormone (GnRH) agonist has been used in the treatment of a wide variety of sex-hormone-related diseases, as the administration of GnRH agonist can alter the secretion of gonadotropin and sex hormones. Recently, we found that the long-acting GnRH agonist aggravated hyperthyroidism and induced painless thyroiditis. This is the first report to demonstrate the association of thyroid dysfunction with GnRH agonist injection in Korea. Here, we report three cases and emphasize the clinical importance of this aggravating factor in autoimmune thyroid disease.


Citations to this article as recorded by  
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  • The impact of thyroid autoimmunity on IVF/ICSI outcome: a systematic review and meta-analysis
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    Human Reproduction Update.2016; 22(6): 775.     CrossRef
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  • Brief Review of Articles in 'Endocrinology and Metabolism' in 2013
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    Endocrinology and Metabolism.2014; 29(3): 251.     CrossRef
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