KES
Search
- Page Path
- HOME > Search
Case Reports
- A Case of Insulinoma Diagnosed as Epilepsy for 7 Years.
- Jong Su Kim, Hyung Gyung Choi, Eun Suk Choi, Soo Ryong Jung, Chung Huh, Jin Kwan Lee
- J Korean Endocr Soc. 1994;9(3):265-271. Published online November 6, 2019
- 1,182 View
- 21 Download
-
Abstract
PDF - Insulinoma is rare functioning islet cell tumor of pancreas and its main feature is frequent attacks of hypoglycemia. Because of frequent seizure, the disease is occasionally mistook as epilepy. We experienced a case of insulinoma with dilantin toxicity in a 45 year old patient who had been treated with dilantin for 7 years. Selective splenic arteriogram showed 0.8cm mass in the tail of pancreas which was proven insulin secreting tumor on histiopathological examination. After operation no more seizure attack was detected and her blood sugar level was well maintained within normal range. This case might provide an insight that the possibility of insulinoma should be considered in patient with episodic neurobehavioral dysfunction such as epilepsy.
- A Case of Central Diabetes Insipitus Combined with Septo-Optic Dysplasia and Schizencephaly in 31-year-old Woman.
- Soo Kyoung Kim, Tae Sik Jung, Jong Ryeal Hahm, Sang Min Lee, Sung Won Moon, Kyeong Ju Lee, Soon Il Chung
- J Korean Endocr Soc. 2007;22(5):339-343. Published online October 1, 2007
- DOI: https://doi.org/10.3803/jkes.2007.22.5.339
- 2,372 View
- 20 Download
- 2 Crossref
-
Abstract
PDF
- A 31-year-old woman was referred to our hospital for evaluation and management of poorly controlled epilepsy. The patient had been taking anti-epileptic drugs for six years. An MRI imaging study showed septo-optic dysplasia (SOD) and schizencephaly. SOD is a syndrome characterized by agenesis of the septum pellucidum or corpus callosum, optic nerve dysplasia and congenital hypothalamic-pituitary insufficiency. The patient was referred to the endocrine clinic for exclusion of any pituitary hormonal deficiencies. In a systemic review, the patient complained of polydipsia and polyuria for 20 years. In laboratory tests, measurements showed a serum osmolarity of 281 mOsm/kg, a serum sodium concentration of 144.7 mmol/L, a spot urine osmolarity of 183 mOsm/kg and a spot urine sodium concentration of 32 mmol/L. The patient underwent a water deprivation test, and was diagnosed with central diabetes insipidus. We report a case of central diabetes insipitus combined with SOD, schizencephaly and epilepsy.
-
Citations
Citations to this article as recorded by
- A Case of Septo-Optic Dysplasia Resulting in Central Diabetes Insipidus and Nonobstructive Bilateral Hydronephrosis
Jong Hyun Kim, Kwang Bok Lee, Jeonghun Lee, Soo Min Nam, Kang-Woo Lee, Eu Gene Hwang, Geon Gil
Korean Journal of Medicine.2014; 87(2): 209. CrossRef - A Case of Septo-optic Dysplasia Associated with Anterior Pituitary Hormone Abnormalities
Jin-Woo Lee, Eui-Kyung Hwang, Tae-Ho Kim, Hyung-Young Yoon, Jae Ho Jung, Yong Won Choi, Suk-Woo Yong, Jae-Hong Ahn, Sun-Yong Kim, Ho Sung Kim, Yoon-Sok Chung
Journal of Korean Endocrine Society.2009; 24(1): 33. CrossRef
- A Case of Septo-Optic Dysplasia Resulting in Central Diabetes Insipidus and Nonobstructive Bilateral Hydronephrosis
Original Article
- Adverse Effects of Antiepileptic Drugs on Bone Mineral Density in Women with Epilepsy.
- Yong Won Cho, In Kyu Lee, Seung Ho Hur
- J Korean Endocr Soc. 2002;17(2):218-225. Published online April 1, 2002
- 1,095 View
- 18 Download
-
Abstract
PDF
- BACKGROUND
Osteoporosis or osteopenia has been reported in patients taking antiepileptic drugs, but the precise pathophysiological mechanisms of these abnormalities are unclear. The aim of this study was to assess the relationship of antiepileptic drugs on bone mass by analyzing bone mineral density (BMD). METHODS: We compared 62 epileptic women on long-term antiepileptic therapy the same number of age and weight matched healthy control subjects. We measured the serum calcium, phosphorus, protein, alkaline phosphatase and osteocalcin for analyzing factors, that have an influence on bone metabolism and BMD. BMD was measured on the lumbar spine by dual-energy X-ray absorptiometry. RESULTS: The serum level of calcium and osteocalcin were not different between the groups. The serum level of phosphorus and protein were significantly lower in the patient group compared to their controls. The serum level of alkaline phosphatase was significantly higher in the patient group than in their controls. The BMD was significantly lower in the patient group than in their controls. There was a significant correlation between the BMD and the duration of therapy in the patient group. CONCLUSION: The long-term use of antiepileptic drugs leads to a decreased BMD, and the degree of bone mineral density was related to the duration of the therapeutic use of antiepileptics.
First
Prev
