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Volume 23(2); April 2008
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Review Articles
MEPE: A Mineralization Regulating Bone Matrix Protein.
Youngdan Cho, Hyeon Mo Ryoo
J Korean Endocr Soc. 2008;23(2):71-75.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.71
  • 1,205 View
  • 18 Download
  • 1 Citations
AbstractAbstract PDF
No abstract available.

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  • Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS Data
    Olivia L. Sabik, Gina M. Calabrese, Eric Taleghani, Cheryl L. Ackert-Bicknell, Charles R. Farber
    Cell Reports.2020; 32(11): 108145.     CrossRef
Osteoporosis Diagnosis and Treatment 2007.
Ho Yeon Chung
J Korean Endocr Soc. 2008;23(2):76-108.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.76
  • 1,496 View
  • 33 Download
  • 22 Citations
AbstractAbstract PDF
No abstract available.

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  • Sex-specific bi‑directional association between osteoporosis and depression from the national representative data of South Korea
    Min Kyoung Shin, Hyejin Kim, Soo-Hee Choi, Beom-Jun Kim, Obin Kwon
    Scientific Reports.2022;[Epub]     CrossRef
  • Effects of Herbal Medicines on Osteoporosis in Rheumatoid Arthritis: Study Protocol for a Systematic Review and Meta-Analysis
    Do Young Kwon, Ji Hyang Gu, Eun Jung Lee
    Journal of Korean Medicine Rehabilitation.2022; 32(3): 77.     CrossRef
  • Development and Effect Analysis of UVB-LED General Lighting to Support Vitamin D Synthesis
    Seung-Taek Oh, Jae-Hyun Lim
    Applied Sciences.2020; 10(3): 889.     CrossRef
  • Effect of Cheongawongagam Extract on the Ovariectomized Rat Model of Osteoporosis
    Gee Won Yun, Hyun Lee
    Journal of Physiology & Pathology in Korean Medicine.2020; 34(1): 14.     CrossRef
  • Survey on Usage of Korean Quantitative Ultrasound for Proposing Quantitative Ultrasound Quality Control Guideline
    Jeong Yoon-Ji, Kim Mi-Jeong, Lee Seung-Youl, Lee Tae-Hee, Seoung Youl-Hun
    Journal of Radiological Science and Technology.2018; 41(4): 329.     CrossRef
  • Comparison of the Effects of Deer Antler, Old Antler, and Antler Glue on Osteoporosis in Ovariectomized Rats
    Hae In Park, Kwang Ho Lee
    Journal of Acupuncture Research.2018; 35(1): 21.     CrossRef
  • Influence of Cortical Endplates on Ultrasonic Properties of Trabecular Bone
    Yoon Mi Kim, Kang Il Lee
    Journal of the Korean Society for Nondestructive Testing.2015; 35(2): 103.     CrossRef
  • Inhibitory Effects of on Osteoclast Differentiation and Bone Resorption
    Jeong Ju Lee, So Hyun Jo, Min Cheol Park, Eun Heui Jo
    The Acupuncture.2015; 32(3): 27.     CrossRef
  • Factor Analysis of Biochemical Markers Associated with Bone Mineral Density in Adults
    Jae-Hwan Cho, Min-Tae Kim, Hae-Kag Lee, In-Sik Hong, Hyon-Chol Jang
    Journal of Physical Therapy Science.2014; 26(8): 1225.     CrossRef
  • The Association between Changes in Food and Nutrient Intakes and Changes in Bone Metabolic Indicators in Postmenopausal Women with Osteopenia after a 12-week Intervention of Nutrition Education and Aerobic Exercise
    Seo-Jin Kim, Suh-Jung Kang, Yoon Jung Park, Ji-Yun Hwang
    Korean Journal of Community Nutrition.2013; 18(3): 213.     CrossRef
  • Omega-3 and Menopause
    Tae-Hee Kim, Dong Won Byun, Yongsoon Park
    The Journal of Korean Society of Menopause.2012; 18(2): 75.     CrossRef
  • Comparative Study of Osteoporosis Treatment of Elderly Patients with Degenerative Osteoarthritis of the Knee Joints, according to the Korean Health Insurance Review & Assessment Service Criteria versus the FRAX® Criteria
    Su Chan Lee, Chang Hyun Nam, Ji Yeol Yoon, Kwang Am Jung, Bo Hyun Hwang, Hye Sun Ahn
    Journal of the Korean Orthopaedic Association.2012; 47(5): 368.     CrossRef
  • Dependences of Ultrasonic Parameters for Osteoporosis Diagnosis on Bone Mineral Density
    Kyo Seung Hwang, Yoon Mi Kim, Jong Chan Park, Min Joo Choi, Kang Il Lee
    Journal of the Korean Society for Nondestructive Testing.2012; 32(5): 502.     CrossRef
  • The Beneficial Effect of Leisure-Time Physical Activity on Bone Mineral Density in Pre- and Postmenopausal Women
    Kyee-Zu Kim, Aesun Shin, Jeonghee Lee, Seung-Kwon Myung, Jeongseon Kim
    Calcified Tissue International.2012; 91(3): 178.     CrossRef
  • The Clinical Significance of Adjacent Rib Involvement on MRI in Patients with Acute Osteoporotic Compression Fractures of the Thoracic Spine
    Hyun-Joo Kim, Jae Hyun Kim, Kui Hyang Kwon, Deuk Lin Choi, Won Kyung Bae, Dong Erk Goo, You-Sung Suh
    Journal of the Korean Society of Radiology.2012; 66(5): 473.     CrossRef
  • A Case of Multiple Osteoporotic Compression Fractures in Young Man with Budd-Chiari Syndrome
    Sun Hwa Kim, Tae Un Yang, Byeong Kwang Choi, Hye Jin Yoo, Ji A Seo, Kyung Mook Choi, Nan Hee Kim, Sin Gon Kim, Sei Hyun Baik, Dong Seop Choi, Hae Yoon Choi
    Endocrinology and Metabolism.2012; 27(4): 334.     CrossRef
  • Effect of Pig Skin Gelatin Hydrolysates on the Bone Mineral Density of Ovariectomized Rats
    Jeong-Eun Park, Jun-Sang Ham, Hey-Kyung Kim, Chi-Ho Lee, Dong-Wook Kim, Kuk-Hwan Seol, Mi-Hwa Oh, Dong-Hun Kim, Ae-Ra Jang
    Korean Journal for Food Science of Animal Resources.2012; 32(2): 234.     CrossRef
  • The relationship between the bone mineral density and urinary cadmium concentration of residents in an industrial complex
    Minah Shin, Domyung Paek, Chungsik Yoon
    Environmental Research.2011; 111(1): 101.     CrossRef
  • Prevalence, Pathophysiology, Screening and Management of Osteoporosis in Gastric Cancer Patients
    Jung Sub Lim, Jong-Inn Lee
    Journal of Gastric Cancer.2011; 11(1): 7.     CrossRef
  • Relationship between vitamin K status, bone mineral density, and hs-CRP in young Korean women
    Misung Kim, Heeseon Kim, Cheongmin Sohn
    Nutrition Research and Practice.2010; 4(6): 507.     CrossRef
  • Analysis of Risk Factors for Low Bone Mineral Density in Patients with Inflammatory Bowel Disease
    Jae Jung Park, Sung-Ae Jung, Young Wook Noh, Min-Jung Kang, Ji Min Jung, Seong-Eun Kim, Hye-Kyung Jung, Ki-Nam Shim, Tae Hun Kim, Kwon Yoo, Il Hwan Moon, Young Sun Hong
    The Korean Journal of Gastroenterology.2010; 55(4): 237.     CrossRef
  • Restoration of Bone Turnover Rate After Decompression Surgery in Patients With Symptomatic Lumbar Spinal Stenosis
    Ho-Joong Kim, Hwan-Mo Lee, Heoung-Jae Chun, Kyoung-Tak Kang, Hak-Sun Kim, Jin-Oh Park, Eun-Su Moon, Kwang-Hwan Park, Seong-Hwan Moon
    Spine.2009; 34(18): E635.     CrossRef
Editorial
The Characteristics and Follow-up of Pituitary Incidentaloma.
Cheol Ryong Ku, Eun Jig Lee
J Korean Endocr Soc. 2008;23(2):109-110.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.109
  • 1,316 View
  • 17 Download
AbstractAbstract PDF
No abstract available.
Original Articles
Characteristics and Natural Course of Pituitary Incidentaloma in Korea.
You Jin Lee, Sun Wook Cho, Sang Wan Kim, Chan Soo Shin, Kyong Soo Park, Bo Youn Cho, Hong Kyu Lee, Seong Yeon Kim
J Korean Endocr Soc. 2008;23(2):111-116.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.111
  • 1,314 View
  • 16 Download
  • 3 Citations
AbstractAbstract PDF
BACKGROUND
A pituitary incidentaloma is a pituitary mass discovered incidentally by computed tomography (CT) or magnetic resonance (MRI) of the brain performed for evaluation of an unrelated disease, and when the patient did not show neurological or endocrine signs and symptoms. Despite of increasing incidence, only a few studies have reported on characteristics, natural history, treatment, or follow-up strategy. Moreover no epidemiologic data exist on pituitary incidentaloma in Korean. METHODS: We retrospectively enrolled subjects diagnosed as pituitary incidentaloma in Seoul National University Hospital from January 1992 to August 2006. We reviewed baseline demographic findings and the results of basal hormone tests, visual field test, and MRI (or CT) at baseline and during follow-up. RESULTS: Among 1310 patients with pituitary adenoma, 161 subjects were diagnosed with incidentaloma. The subject age at diagnosis was 49.7 +/- 15.5 years, with 84 males. Macroadenoma was more frequent (n = 110, 68.3%). with microadenomas and Rathke's cleft cysts found in 21 and 30 cases, respectively. The mean diameter of the tumor was 1.75 cm. Functional incidentalomas such as prolactinoma or acromegaly were found in 31 cases (19.3%) although there were no symptoms or visual field defects. Of 61 incidentaloma patients who did not undergo surgery or other treatment over one year, only 3 patient showed an increase in tumor size during the mean 38.0 +/- 24.9 months follow-up. CONCLUSION: Pituitary incidentaloma generally showed a benign course despite the high prevalence of macroadenoma (68.3%). However, as about 20% of the patients had functioning tumors, pituitary hormonal evaluation at diagnosis is mandatory. Furthermore, as we experienced 3 cases with increased tumor size during follow up, including a case of pituitary microadenoma, long-term careful follow-up of pituitary incidentaloma seems necessary. A long-term, prospective study with more patients would reveal the characteristics and the natural history of pituitary incidentalomas in Korea.

Citations

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  • Sellar Masses: An Epidemiological Study
    Khaled Al-Dahmani, Syed Mohammad, Fatima Imran, Chris Theriault, Steve Doucette, Deborah Zwicker, Churn-Ern Yip, David B. Clarke, Syed Ali Imran
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.2016; 43(2): 291.     CrossRef
  • Optimal Surgical Approaches for Rathke Cleft Cyst With Consideration of Endocrine Function
    Jeong Kyung Park, Eun Jig Lee, Sun Ho Kim
    Operative Neurosurgery.2012; 70: ons250.     CrossRef
  • Clinical Characteristics of 16 Patients with Pituitary Tumor Incidentally Detected by18F-Fluorodeoxyglucose PET-CT (18F-FDG PET-CT)
    Hyung Jin Kim, Gi Jeong Cheon, A Ra Cho, Chang Hoon Lee, Sang Min Youn, Se jin Ahn, Sang Eon Jang, Jung Min Kim, Yun Yong Lee, Ka Hee Yi
    Endocrinology and Metabolism.2010; 25(4): 321.     CrossRef
CAG Repeats in the Androgen Receptor Polymorphism do not Correlate with Thyrotoxic Periodic Paralysis.
Won Gu Kim, Tae Yong Kim, Jung Min Kim, Yoon Soo Rhee, Hyun Jeung Choi, Won Bae Kim, Young Kee Shong
J Korean Endocr Soc. 2008;23(2):117-122.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.117
  • 1,428 View
  • 19 Download
  • 3 Citations
AbstractAbstract PDF
BACKGROUND
Thyrotoxic periodic paralysis (TPP) occurs mostly in males, but no studies have addressed the role of androgen in the disease. Hyperinsulinemia can precipitate acute paralysis in TPP patients. CAG repeats in the androgen receptor (AR), an X-linked gene, correlate with serum insulin levels. AIM: To evaluate whether CAG repeats in the AR gene might predict the susceptibility to TPP in Korean male Graves' patients. METHODS: We evaluated CAG repeat length in a series of 33 male TPP patients and 48 control patients by direct sequencing of the PCR product of the AR promoter site. Control patients were male Graves' patients without a history of paralysis. RESULTS: The CAG repeat length varied from 15 to 34 (median of 23). The upper quartile of CAG length was equal to or above 26 repeats (long AR). The distribution of long AR was 0.30 in TPP and 0.15 in control patients, respectively (odds ratio, 2.51; 95% confidence interval, 0.92~6.85; P = 0.09). CONCLUSION: AR gene polymorphisms may not confer genetic susceptibility to TPP in Korean male patients with Graves' disease.

Citations

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  • Contributions of CAG repeat length in the androgen receptor gene and androgen profiles to premature pubarche in Korean girls
    Min Jae Kang, Jeong Seon Lee, Hwa Young Kim, Hae Woon Jung, Young Ah Lee, Sun Hee Lee, Ji-Young Seo, Jae Hyun Kim, Hye Rim Chung, Se Young Kim, Choong Ho Shin, Sei Won Yang
    Endocrine Journal.2017; 64(1): 91.     CrossRef
  • Thyrotoxic Periodic Paralysis and Polymorphisms of the ADRB2, AR, and GABRA3 Genes in Men with Graves Disease
    Suyeon Park, Tae Yong Kim, Soyoung Sim, Seonhee Lim, Mijin Kim, Hyemi Kwon, Min Ji Jeon, Won Gu Kim, Young Kee Shong, Won Bae Kim
    Endocrinology and Metabolism.2016; 31(1): 142.     CrossRef
  • Androgen Receptor Gene CAG Repeat Polymorphism and Effect of Testosterone Therapy in Hypogonadal Men in Korea
    Min Joo Kim, Jin Taek Kim, Sun Wook Cho, Sang Wan Kim, Chan Soo Shin, Kyong Soo Park, Seong Yeon Kim
    Endocrinology and Metabolism.2011; 26(3): 225.     CrossRef
Association between Cigarette Smoking and Thyroid Function in Adults without Previous History of Thyroid Disease.
Bo Hyun Kim, Won Bae Kim, Tae Yong Kim, Hong Kyu Kim, Seong Hoon Jeon, Chang Won Lee, Young Kee Shong
J Korean Endocr Soc. 2008;23(2):123-128.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.123
  • 1,733 View
  • 27 Download
  • 3 Citations
AbstractAbstract PDF
BACKGROUND
Cigarette smoking has a significant impact on thyroid function. However, the association between smoking and thyroid function is incompletely understood. METHODS: We conducted a cross-sectional study that included 90,970 adults (age range: 20 to 79) who had visited the health promotion center at Asan Medical Center between January 1, 2001, and December 31, 2003. Those subjects with previous known thyroid disease, a history of thyroid operation, a history of thyroid function altering medication (herb, estrogen or digestive) or a family history of thyroid disease were excluded. Finally, 47,577 subjects (males: 30,726, females: 16,851) were included in this study. We calculated the age-adjusted geometric mean of the serum TSH and the age-adjusted mean of the serum free T4 among the current, former and never smokers. We also analyzed the age-adjusted prevalence of hypothyroidism and hyperthyroidism among each group. RESULTS: Among men, the geometric mean TSH level was significantly low in the current (1.40 mIU/L, 95% confidence interval [CI]: 1.38-1.41) and former smokers (1.59 mIU/L, 95% CI: 1.57-1.61) compared with the never smokers (1.65 mIU/L, 95% CI: 1.63-1.68). The mean free T4 level was high in the current smokers (1.236 ng/dL, 95% CI: 1.234-1.239) compared with the never smokers (1.234 ng/dL, 95% CI: 1.230-1.238). Similarly, among women, the geometric mean TSH level was low in the current smokers (1.75 mIU/L, 95% CI: 1.67-1.87) compared with the never smokers (1.85 mIU/L, 95% CI: 1.83-1.87). The mean free T4 level was high in the current smokers (1.149 ng/dL, 95% CI: 1.139-1.159) compared with the never smokers (1.138 ng/dL, 95% CI: 1.135-1.140). Among the current male smokers, heavy daily smoking (over 2 packs per day) was more associated with low TSH levels than moderate smoking (less than 1 pack per day). In men, the prevalence of subclinical hypothyroidism was low in the current smokers compared with the never smokers (odds ratio: 0.53, 95% CI: 0.43-0.66). CONCLUSION: We found that current smokers had lower TSH levels and higher free T4 levels than never smokers in both men and women and smoking was associated with a low prevalence of subclinical hypothyroidism in men, which may be of importance when evaluating subjects with subclinical hypothyroidism in Korea.

Citations

Citations to this article as recorded by  
  • Reference interval for thyrotropin in a ultrasonography screened Korean population
    Mijin Kim, Tae Yong Kim, Soo Han Kim, Yunkyoung Lee, Su-yeon Park, Hyung-don Kim, Hyemi Kwon, Yun Mi Choi, Eun Kyung Jang, Min Ji Jeon, Won Gu Kim, Young Kee Shong, Won Bae Kim
    The Korean Journal of Internal Medicine.2015; 30(3): 335.     CrossRef
  • Clinical Review of Thyroid Dysfunction in the Subjects for Health Check-up
    Ji Eun Park, Ho Chan Cho
    Journal of Korean Thyroid Association.2012; 5(1): 52.     CrossRef
  • Thyroid Dysfunction of North Korean Women Living in South Korea, Focusing on Subclinical Hypothyroidism
    Joo Hyung Kim, Sol Ah Park, Nam Hoon Kim, Jae Hee Ahn, Yoon Jung Kim, Myongjin Cho, Yoon Jung Lee, Hye Jin Yoo, Hee Young Kim, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Sin Gon Kim
    Endocrinology and Metabolism.2012; 27(3): 200.     CrossRef
Effects of S-allylcysteine on Oxidative Stress in Streptozotocin-Induced Diabetic Rats.
Chul Ho Shin, Jahei Ihm
J Korean Endocr Soc. 2008;23(2):129-136.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.129
  • 1,348 View
  • 20 Download
  • 3 Citations
AbstractAbstract PDF
BACKGROUND
An increase in oxidative stress is postulated to contribute to the development of diabetic complications and the use of antioxidant therapy could be protective against these processes. This study was performed to investigate the role of the antioxidant S-allylcysteine (SAC), a water-soluble component of aged garlic, for reducing levels of oxidative stress that occurs in diabetic rats. METHODS: SAC (100 mg/head/day) was administered orally to streptozotocin-induced diabetic rats for eight weeks. The effects of SAC on the levels of markers of oxidative stress (malondialdehyde and glutathione) and mRNA expression of antioxidant enzymes were measured in the liver and kidney. RESULTS: SAC-fed rats showed lower cholesterol and triacylglyceride levels than untreated diabetic rats. Malondialdehyde levels were increased in the liver and kidney of diabetic rats and SAC administration lowered the levels in both organs. Glutathione levels were lower in the liver and kidney of diabetic rats, and SAC administration restored the glutathione to a level similar in non-diabetic rats. In the liver and kidney of untreated diabetic rats, mRNA expression of catalase, superoxide dismutase and glutathione reductase were down regulated, and administration of SAC increased expression of these enzymes. CONCLUSION: Our results have shown that administration of SAC to diabetic rats can lower blood lipid levels and alleviate oxidative stress in the diabetic tissues, suggesting that SAC might have beneficial effects in a prevention trial for diabetic complications.

Citations

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  • Effect of Garlic and Aged Black Garlic on Hyperglycemia and Dyslipidemia in Animal Model of Type 2 Diabetes Mellitus
    Yeong-Ju Seo, Oh-Cheon Gweon, Ji-Eun Im, Young-Min Lee, Min-Jung Kang, Jung-In Kim
    Preventive Nutrition and Food Science.2009; 14(1): 1.     CrossRef
  • Antioxidant effect of garlic and aged black garlic in animal model of type 2 diabetes mellitus
    Young-Min Lee, Oh-Cheon Gweon, Yeong-Ju Seo, Jieun Im, Min-Jung Kang, Myo-Jeong Kim, Jung-In Kim
    Nutrition Research and Practice.2009; 3(2): 156.     CrossRef
  • Effects of Adenophora triphylla Ethylacetate Extract on mRNA Levels of Antioxidant Enzymes in Human HepG2 Cells
    Hyun-Jin Choi, Soo-Hyun Kim, Hyun-Taek Oh, Mi-Ja Chung, Cheng-Bi Cui, Seung-Shi Ham
    Journal of the Korean Society of Food Science and Nutrition.2008; 37(10): 1238.     CrossRef
Case Reports
Non-functional Pituitary Adenoma Detected on (18)F-fluorodeoxyglucose Positron Emission Tomography ((18)F-FDG-PET) in a Patient with Mucosa-associated Lymphoid Tissue Lymphoma.
Jin Ha Lee, Seung Jin Han, Se Eun Park, Mi Ae Cho, June Won Cheong, Mijin Yun, Yumie Rhee, Eun Jig Lee, Sung Kil Lim
J Korean Endocr Soc. 2008;23(2):137-141.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.137
  • 1,451 View
  • 18 Download
  • 1 Citations
AbstractAbstract PDF
Magnetic resonance imaging (MRI) is the modality of choice for the detection and characterization of a pituitary adenoma. Uptake of (18)F-fluorodeoxyglucose (FDG) by intrasellar tumors, including pituitary adenomas, has been reported in several previous studies. We report a case where a pituitary adenoma was detected on FDG-positron emission tomography (PET), but the tumor was not detected with the use of sellar MRI. A 31-year-old woman was referred to the clinic due to a focal increase of FDG uptake at the pituitary fossa seen on whole body FDG-PET. The patient was receiving chemotherapy due to a recurred B-cell lymphoma of the mucosa-associated lymphoid tissue type. Subsequently, sellar MRI was performed, and images showed a small non-enhancing heterogenous cystic lesion in the midline of the pituitary gland, radiologically suggestive of a Rathke's cleft cyst. However, sellar MRI failed to identify a lesion consistent with a pituitary tumor that corresponded to the site of increased FDG uptake detected by the use of PET, despite the inclusion of a dynamic contrast enhanced sequence. Despite the negative findings of the MRI examination, basal and stimulated levels of the GnRH free alpha-subunit were profoundly increased. Therefore, we suspected the presence of a non-functional pituitary tumor in addition to a Rathke's cleft cyst, rather than pituitary involvement of a lymphoma, based on the hormone levels and PET scan findings.

Citations

Citations to this article as recorded by  
  • Clinical Characteristics of 16 Patients with Pituitary Tumor Incidentally Detected by18F-Fluorodeoxyglucose PET-CT (18F-FDG PET-CT)
    Hyung Jin Kim, Gi Jeong Cheon, A Ra Cho, Chang Hoon Lee, Sang Min Youn, Se jin Ahn, Sang Eon Jang, Jung Min Kim, Yun Yong Lee, Ka Hee Yi
    Endocrinology and Metabolism.2010; 25(4): 321.     CrossRef
A Case of Lymphocytic Infundibuloneurohypophysitis Along with Central Diabetes Insipidus, and this Improved with Conservative Care.
Ji Myoung Lee, Sang Mi Park, Byung Hee Hwang, Hyun Sook Choi, Seong Su Lee, Jee Young Kim, Sung Rae Kim, Kwang Woo Lee, Ho Young Son, Sung Koo Kang, Soon Jib Yoo
J Korean Endocr Soc. 2008;23(2):142-147.   Published online April 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.2.142
  • 1,518 View
  • 20 Download
AbstractAbstract PDF
Idiopathic central diabetes insipidus is most likely to occur in young patients who have a clinical history of autoimmune disease. The presentation of clinical findings such as central diabetes insipidus and pituitary stalk thickening on sellar magnetic resonance imaging (MRI) in a young women would strongly suggest lymphocytic hypophysitis, which is a rare inflammatory process involving the pituitary stalk and the pituitary gland, yet this disease can sometimes regress.

Endocrinol Metab : Endocrinology and Metabolism