Endocrinology and Metabolism

Volume 23(2); April 2008

Review Articles

MEPE: A Mineralization Regulating Bone Matrix Protein.: Youngdan Cho, Hyeon Mo Ryoo; J Korean Endocr Soc. 2008;23(2):71-75. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.71

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No abstract available.

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Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS Data
Olivia L. Sabik, Gina M. Calabrese, Eric Taleghani, Cheryl L. Ackert-Bicknell, Charles R. Farber
Cell Reports.2020; 32(11): 108145. CrossRef

Osteoporosis Diagnosis and Treatment 2007.: Ho Yeon Chung; J Korean Endocr Soc. 2008;23(2):76-108. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.76

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Abstract PDF

No abstract available.

Citations

Citations to this article as recorded by

Parameter estimation-based discrimination method for osteoporosis stage with ultrasound bone densitometer
Yuna Choi, Jaehyun Kim, Gwangyeol Cha, Youngjin Choi, Il Youn Jung, Bong Gun Lee, Chang-Hun Lee
Scientific Reports.2024;[Epub] CrossRef
Preliminary Study on the Osteoporosis Improvement Effect of Compounds Isolated from Oryza sativa L. root Extract in the Ovariectomized Mouse Model
Seon-Hee Kim, Eun-Yong Choi, Hee-Jin Yang, Jun Sang Bae
Journal of Physiology & Pathology in Korean Medicine.2023; 37(2): 30. CrossRef
Sex-specific bi‑directional association between osteoporosis and depression from the national representative data of South Korea
Min Kyoung Shin, Hyejin Kim, Soo-Hee Choi, Beom-Jun Kim, Obin Kwon
Scientific Reports.2022;[Epub] CrossRef
Effects of Herbal Medicines on Osteoporosis in Rheumatoid Arthritis: Study Protocol for a Systematic Review and Meta-Analysis
Do Young Kwon, Ji Hyang Gu, Eun Jung Lee
Journal of Korean Medicine Rehabilitation.2022; 32(3): 77. CrossRef
Effects of Adolescents’ Lifestyle Habits and Body Composition on Bone Mineral Density
Chang-Sook Han, Hyo-Kyung Kim, Suhee Kim
International Journal of Environmental Research and Public Health.2021; 18(11): 6170. CrossRef
Development and Effect Analysis of UVB-LED General Lighting to Support Vitamin D Synthesis
Seung-Taek Oh, Jae-Hyun Lim
Applied Sciences.2020; 10(3): 889. CrossRef
Effect of Cheongawongagam Extract on the Ovariectomized Rat Model of Osteoporosis
Gee Won Yun, Hyun Lee
Journal of Physiology & Pathology in Korean Medicine.2020; 34(1): 14. CrossRef
Survey on Usage of Korean Quantitative Ultrasound for Proposing Quantitative Ultrasound Quality Control Guideline
Jeong Yoon-Ji, Kim Mi-Jeong, Lee Seung-Youl, Lee Tae-Hee, Seoung Youl-Hun
Journal of Radiological Science and Technology.2018; 41(4): 329. CrossRef
Comparison of the Effects of Deer Antler, Old Antler, and Antler Glue on Osteoporosis in Ovariectomized Rats
Hae In Park, Kwang Ho Lee
Journal of Acupuncture Research.2018; 35(1): 21. CrossRef
Influence of Cortical Endplates on Ultrasonic Properties of Trabecular Bone
Yoon Mi Kim, Kang Il Lee
Journal of the Korean Society for Nondestructive Testing.2015; 35(2): 103. CrossRef
Inhibitory Effects of Yongbu-tang on Osteoclast Differentiation and Bone Resorption※
Jeong Ju Lee, So Hyun Jo, Min Cheol Park, Eun Heui Jo
The Acupuncture.2015; 32(3): 27. CrossRef
Factor Analysis of Biochemical Markers Associated with Bone Mineral Density in Adults
Jae-Hwan Cho, Min-Tae Kim, Hae-Kag Lee, In-Sik Hong, Hyon-Chol Jang
Journal of Physical Therapy Science.2014; 26(8): 1225. CrossRef
The Association between Changes in Food and Nutrient Intakes and Changes in Bone Metabolic Indicators in Postmenopausal Women with Osteopenia after a 12-week Intervention of Nutrition Education and Aerobic Exercise
Seo-Jin Kim, Suh-Jung Kang, Yoon Jung Park, Ji-Yun Hwang
Korean Journal of Community Nutrition.2013; 18(3): 213. CrossRef
Omega-3 and Menopause
Tae-Hee Kim, Dong Won Byun, Yongsoon Park
The Journal of Korean Society of Menopause.2012; 18(2): 75. CrossRef
Comparative Study of Osteoporosis Treatment of Elderly Patients with Degenerative Osteoarthritis of the Knee Joints, according to the Korean Health Insurance Review & Assessment Service Criteria versus the FRAX® Criteria
Su Chan Lee, Chang Hyun Nam, Ji Yeol Yoon, Kwang Am Jung, Bo Hyun Hwang, Hye Sun Ahn
Journal of the Korean Orthopaedic Association.2012; 47(5): 368. CrossRef
Dependences of Ultrasonic Parameters for Osteoporosis Diagnosis on Bone Mineral Density
Kyo Seung Hwang, Yoon Mi Kim, Jong Chan Park, Min Joo Choi, Kang Il Lee
Journal of the Korean Society for Nondestructive Testing.2012; 32(5): 502. CrossRef
The Beneficial Effect of Leisure-Time Physical Activity on Bone Mineral Density in Pre- and Postmenopausal Women
Kyee-Zu Kim, Aesun Shin, Jeonghee Lee, Seung-Kwon Myung, Jeongseon Kim
Calcified Tissue International.2012; 91(3): 178. CrossRef
The Clinical Significance of Adjacent Rib Involvement on MRI in Patients with Acute Osteoporotic Compression Fractures of the Thoracic Spine
Hyun-Joo Kim, Jae Hyun Kim, Kui Hyang Kwon, Deuk Lin Choi, Won Kyung Bae, Dong Erk Goo, You-Sung Suh
Journal of the Korean Society of Radiology.2012; 66(5): 473. CrossRef
A Case of Multiple Osteoporotic Compression Fractures in Young Man with Budd-Chiari Syndrome
Sun Hwa Kim, Tae Un Yang, Byeong Kwang Choi, Hye Jin Yoo, Ji A Seo, Kyung Mook Choi, Nan Hee Kim, Sin Gon Kim, Sei Hyun Baik, Dong Seop Choi, Hae Yoon Choi
Endocrinology and Metabolism.2012; 27(4): 334. CrossRef
Effect of Pig Skin Gelatin Hydrolysates on the Bone Mineral Density of Ovariectomized Rats
Jeong-Eun Park, Jun-Sang Ham, Hey-Kyung Kim, Chi-Ho Lee, Dong-Wook Kim, Kuk-Hwan Seol, Mi-Hwa Oh, Dong-Hun Kim, Ae-Ra Jang
Korean Journal for Food Science of Animal Resources.2012; 32(2): 234. CrossRef
The relationship between the bone mineral density and urinary cadmium concentration of residents in an industrial complex
Minah Shin, Domyung Paek, Chungsik Yoon
Environmental Research.2011; 111(1): 101. CrossRef
Prevalence, Pathophysiology, Screening and Management of Osteoporosis in Gastric Cancer Patients
Jung Sub Lim, Jong-Inn Lee
Journal of Gastric Cancer.2011; 11(1): 7. CrossRef
Relationship between vitamin K status, bone mineral density, and hs-CRP in young Korean women
Misung Kim, Heeseon Kim, Cheongmin Sohn
Nutrition Research and Practice.2010; 4(6): 507. CrossRef
Analysis of Risk Factors for Low Bone Mineral Density in Patients with Inflammatory Bowel Disease
Jae Jung Park, Sung-Ae Jung, Young Wook Noh, Min-Jung Kang, Ji Min Jung, Seong-Eun Kim, Hye-Kyung Jung, Ki-Nam Shim, Tae Hun Kim, Kwon Yoo, Il Hwan Moon, Young Sun Hong
The Korean Journal of Gastroenterology.2010; 55(4): 237. CrossRef
Restoration of Bone Turnover Rate After Decompression Surgery in Patients With Symptomatic Lumbar Spinal Stenosis
Ho-Joong Kim, Hwan-Mo Lee, Heoung-Jae Chun, Kyoung-Tak Kang, Hak-Sun Kim, Jin-Oh Park, Eun-Su Moon, Kwang-Hwan Park, Seong-Hwan Moon
Spine.2009; 34(18): E635. CrossRef

Editorial

The Characteristics and Follow-up of Pituitary Incidentaloma.: Cheol Ryong Ku, Eun Jig Lee; J Korean Endocr Soc. 2008;23(2):109-110. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.109

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Abstract PDF: No abstract available.

Original Articles

Characteristics and Natural Course of Pituitary Incidentaloma in Korea.: You Jin Lee, Sun Wook Cho, Sang Wan Kim, Chan Soo Shin, Kyong Soo Park, Bo Youn Cho, Hong Kyu Lee, Seong Yeon Kim; J Korean Endocr Soc. 2008;23(2):111-116. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.111

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Abstract PDF

BACKGROUND
A pituitary incidentaloma is a pituitary mass discovered incidentally by computed tomography (CT) or magnetic resonance (MRI) of the brain performed for evaluation of an unrelated disease, and when the patient did not show neurological or endocrine signs and symptoms. Despite of increasing incidence, only a few studies have reported on characteristics, natural history, treatment, or follow-up strategy. Moreover no epidemiologic data exist on pituitary incidentaloma in Korean. METHODS: We retrospectively enrolled subjects diagnosed as pituitary incidentaloma in Seoul National University Hospital from January 1992 to August 2006. We reviewed baseline demographic findings and the results of basal hormone tests, visual field test, and MRI (or CT) at baseline and during follow-up. RESULTS: Among 1310 patients with pituitary adenoma, 161 subjects were diagnosed with incidentaloma. The subject age at diagnosis was 49.7 +/- 15.5 years, with 84 males. Macroadenoma was more frequent (n = 110, 68.3%). with microadenomas and Rathke's cleft cysts found in 21 and 30 cases, respectively. The mean diameter of the tumor was 1.75 cm. Functional incidentalomas such as prolactinoma or acromegaly were found in 31 cases (19.3%) although there were no symptoms or visual field defects. Of 61 incidentaloma patients who did not undergo surgery or other treatment over one year, only 3 patient showed an increase in tumor size during the mean 38.0 +/- 24.9 months follow-up. CONCLUSION: Pituitary incidentaloma generally showed a benign course despite the high prevalence of macroadenoma (68.3%). However, as about 20% of the patients had functioning tumors, pituitary hormonal evaluation at diagnosis is mandatory. Furthermore, as we experienced 3 cases with increased tumor size during follow up, including a case of pituitary microadenoma, long-term careful follow-up of pituitary incidentaloma seems necessary. A long-term, prospective study with more patients would reveal the characteristics and the natural history of pituitary incidentalomas in Korea.

Citations

Citations to this article as recorded by

Sellar Masses: An Epidemiological Study
Khaled Al-Dahmani, Syed Mohammad, Fatima Imran, Chris Theriault, Steve Doucette, Deborah Zwicker, Churn-Ern Yip, David B. Clarke, Syed Ali Imran
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.2016; 43(2): 291. CrossRef
Optimal Surgical Approaches for Rathke Cleft Cyst With Consideration of Endocrine Function
Jeong Kyung Park, Eun Jig Lee, Sun Ho Kim
Operative Neurosurgery.2012; 70: ons250. CrossRef
Clinical Characteristics of 16 Patients with Pituitary Tumor Incidentally Detected by18F-Fluorodeoxyglucose PET-CT (18F-FDG PET-CT)
Hyung Jin Kim, Gi Jeong Cheon, A Ra Cho, Chang Hoon Lee, Sang Min Youn, Se jin Ahn, Sang Eon Jang, Jung Min Kim, Yun Yong Lee, Ka Hee Yi
Endocrinology and Metabolism.2010; 25(4): 321. CrossRef

CAG Repeats in the Androgen Receptor Polymorphism do not Correlate with Thyrotoxic Periodic Paralysis.: Won Gu Kim, Tae Yong Kim, Jung Min Kim, Yoon Soo Rhee, Hyun Jeung Choi, Won Bae Kim, Young Kee Shong; J Korean Endocr Soc. 2008;23(2):117-122. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.117

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Abstract PDF

BACKGROUND
Thyrotoxic periodic paralysis (TPP) occurs mostly in males, but no studies have addressed the role of androgen in the disease. Hyperinsulinemia can precipitate acute paralysis in TPP patients. CAG repeats in the androgen receptor (AR), an X-linked gene, correlate with serum insulin levels. AIM: To evaluate whether CAG repeats in the AR gene might predict the susceptibility to TPP in Korean male Graves' patients. METHODS: We evaluated CAG repeat length in a series of 33 male TPP patients and 48 control patients by direct sequencing of the PCR product of the AR promoter site. Control patients were male Graves' patients without a history of paralysis. RESULTS: The CAG repeat length varied from 15 to 34 (median of 23). The upper quartile of CAG length was equal to or above 26 repeats (long AR). The distribution of long AR was 0.30 in TPP and 0.15 in control patients, respectively (odds ratio, 2.51; 95% confidence interval, 0.92~6.85; P = 0.09). CONCLUSION: AR gene polymorphisms may not confer genetic susceptibility to TPP in Korean male patients with Graves' disease.

Citations

Citations to this article as recorded by

Contributions of CAG repeat length in the androgen receptor gene and androgen profiles to premature pubarche in Korean girls
Min Jae Kang, Jeong Seon Lee, Hwa Young Kim, Hae Woon Jung, Young Ah Lee, Sun Hee Lee, Ji-Young Seo, Jae Hyun Kim, Hye Rim Chung, Se Young Kim, Choong Ho Shin, Sei Won Yang
Endocrine Journal.2017; 64(1): 91. CrossRef
Thyrotoxic Periodic Paralysis and Polymorphisms of the ADRB2, AR, and GABRA3 Genes in Men with Graves Disease
Suyeon Park, Tae Yong Kim, Soyoung Sim, Seonhee Lim, Mijin Kim, Hyemi Kwon, Min Ji Jeon, Won Gu Kim, Young Kee Shong, Won Bae Kim
Endocrinology and Metabolism.2016; 31(1): 142. CrossRef
Androgen Receptor Gene CAG Repeat Polymorphism and Effect of Testosterone Therapy in Hypogonadal Men in Korea
Min Joo Kim, Jin Taek Kim, Sun Wook Cho, Sang Wan Kim, Chan Soo Shin, Kyong Soo Park, Seong Yeon Kim
Endocrinology and Metabolism.2011; 26(3): 225. CrossRef

Association between Cigarette Smoking and Thyroid Function in Adults without Previous History of Thyroid Disease.: Bo Hyun Kim, Won Bae Kim, Tae Yong Kim, Hong Kyu Kim, Seong Hoon Jeon, Chang Won Lee, Young Kee Shong; J Korean Endocr Soc. 2008;23(2):123-128. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.123

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Abstract PDF

BACKGROUND
Cigarette smoking has a significant impact on thyroid function. However, the association between smoking and thyroid function is incompletely understood. METHODS: We conducted a cross-sectional study that included 90,970 adults (age range: 20 to 79) who had visited the health promotion center at Asan Medical Center between January 1, 2001, and December 31, 2003. Those subjects with previous known thyroid disease, a history of thyroid operation, a history of thyroid function altering medication (herb, estrogen or digestive) or a family history of thyroid disease were excluded. Finally, 47,577 subjects (males: 30,726, females: 16,851) were included in this study. We calculated the age-adjusted geometric mean of the serum TSH and the age-adjusted mean of the serum free T4 among the current, former and never smokers. We also analyzed the age-adjusted prevalence of hypothyroidism and hyperthyroidism among each group. RESULTS: Among men, the geometric mean TSH level was significantly low in the current (1.40 mIU/L, 95% confidence interval [CI]: 1.38-1.41) and former smokers (1.59 mIU/L, 95% CI: 1.57-1.61) compared with the never smokers (1.65 mIU/L, 95% CI: 1.63-1.68). The mean free T4 level was high in the current smokers (1.236 ng/dL, 95% CI: 1.234-1.239) compared with the never smokers (1.234 ng/dL, 95% CI: 1.230-1.238). Similarly, among women, the geometric mean TSH level was low in the current smokers (1.75 mIU/L, 95% CI: 1.67-1.87) compared with the never smokers (1.85 mIU/L, 95% CI: 1.83-1.87). The mean free T4 level was high in the current smokers (1.149 ng/dL, 95% CI: 1.139-1.159) compared with the never smokers (1.138 ng/dL, 95% CI: 1.135-1.140). Among the current male smokers, heavy daily smoking (over 2 packs per day) was more associated with low TSH levels than moderate smoking (less than 1 pack per day). In men, the prevalence of subclinical hypothyroidism was low in the current smokers compared with the never smokers (odds ratio: 0.53, 95% CI: 0.43-0.66). CONCLUSION: We found that current smokers had lower TSH levels and higher free T4 levels than never smokers in both men and women and smoking was associated with a low prevalence of subclinical hypothyroidism in men, which may be of importance when evaluating subjects with subclinical hypothyroidism in Korea.

Citations

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Evaluation of Serum Biochemical Parameters Primarily Liver Functions in Smokers: A Case-control Study
Yılmaz Sezgin, Sinan Becel, Abdurrahman Polat
Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi.2024; 13(3): 1125. CrossRef
Reference interval for thyrotropin in a ultrasonography screened Korean population
Mijin Kim, Tae Yong Kim, Soo Han Kim, Yunkyoung Lee, Su-yeon Park, Hyung-don Kim, Hyemi Kwon, Yun Mi Choi, Eun Kyung Jang, Min Ji Jeon, Won Gu Kim, Young Kee Shong, Won Bae Kim
The Korean Journal of Internal Medicine.2015; 30(3): 335. CrossRef
Clinical Review of Thyroid Dysfunction in the Subjects for Health Check-up
Ji Eun Park, Ho Chan Cho
Journal of Korean Thyroid Association.2012; 5(1): 52. CrossRef
Thyroid Dysfunction of North Korean Women Living in South Korea, Focusing on Subclinical Hypothyroidism
Joo Hyung Kim, Sol Ah Park, Nam Hoon Kim, Jae Hee Ahn, Yoon Jung Kim, Myongjin Cho, Yoon Jung Lee, Hye Jin Yoo, Hee Young Kim, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Sin Gon Kim
Endocrinology and Metabolism.2012; 27(3): 200. CrossRef

Effects of S-allylcysteine on Oxidative Stress in Streptozotocin-Induced Diabetic Rats.: Chul Ho Shin, Jahei Ihm; J Korean Endocr Soc. 2008;23(2):129-136. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.129

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Abstract PDF

BACKGROUND
An increase in oxidative stress is postulated to contribute to the development of diabetic complications and the use of antioxidant therapy could be protective against these processes. This study was performed to investigate the role of the antioxidant S-allylcysteine (SAC), a water-soluble component of aged garlic, for reducing levels of oxidative stress that occurs in diabetic rats. METHODS: SAC (100 mg/head/day) was administered orally to streptozotocin-induced diabetic rats for eight weeks. The effects of SAC on the levels of markers of oxidative stress (malondialdehyde and glutathione) and mRNA expression of antioxidant enzymes were measured in the liver and kidney. RESULTS: SAC-fed rats showed lower cholesterol and triacylglyceride levels than untreated diabetic rats. Malondialdehyde levels were increased in the liver and kidney of diabetic rats and SAC administration lowered the levels in both organs. Glutathione levels were lower in the liver and kidney of diabetic rats, and SAC administration restored the glutathione to a level similar in non-diabetic rats. In the liver and kidney of untreated diabetic rats, mRNA expression of catalase, superoxide dismutase and glutathione reductase were down regulated, and administration of SAC increased expression of these enzymes. CONCLUSION: Our results have shown that administration of SAC to diabetic rats can lower blood lipid levels and alleviate oxidative stress in the diabetic tissues, suggesting that SAC might have beneficial effects in a prevention trial for diabetic complications.

Citations

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Effect of Garlic and Aged Black Garlic on Hyperglycemia and Dyslipidemia in Animal Model of Type 2 Diabetes Mellitus
Yeong-Ju Seo, Oh-Cheon Gweon, Ji-Eun Im, Young-Min Lee, Min-Jung Kang, Jung-In Kim
Preventive Nutrition and Food Science.2009; 14(1): 1. CrossRef
Antioxidant effect of garlic and aged black garlic in animal model of type 2 diabetes mellitus
Young-Min Lee, Oh-Cheon Gweon, Yeong-Ju Seo, Jieun Im, Min-Jung Kang, Myo-Jeong Kim, Jung-In Kim
Nutrition Research and Practice.2009; 3(2): 156. CrossRef
Effects of Adenophora triphylla Ethylacetate Extract on mRNA Levels of Antioxidant Enzymes in Human HepG2 Cells
Hyun-Jin Choi, Soo-Hyun Kim, Hyun-Taek Oh, Mi-Ja Chung, Cheng-Bi Cui, Seung-Shi Ham
Journal of the Korean Society of Food Science and Nutrition.2008; 37(10): 1238. CrossRef

Case Reports

Non-functional Pituitary Adenoma Detected on (18)F-fluorodeoxyglucose Positron Emission Tomography ((18)F-FDG-PET) in a Patient with Mucosa-associated Lymphoid Tissue Lymphoma.: Jin Ha Lee, Seung Jin Han, Se Eun Park, Mi Ae Cho, June Won Cheong, Mijin Yun, Yumie Rhee, Eun Jig Lee, Sung Kil Lim; J Korean Endocr Soc. 2008;23(2):137-141. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.137

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Abstract PDF

Magnetic resonance imaging (MRI) is the modality of choice for the detection and characterization of a pituitary adenoma. Uptake of (18)F-fluorodeoxyglucose (FDG) by intrasellar tumors, including pituitary adenomas, has been reported in several previous studies. We report a case where a pituitary adenoma was detected on FDG-positron emission tomography (PET), but the tumor was not detected with the use of sellar MRI. A 31-year-old woman was referred to the clinic due to a focal increase of FDG uptake at the pituitary fossa seen on whole body FDG-PET. The patient was receiving chemotherapy due to a recurred B-cell lymphoma of the mucosa-associated lymphoid tissue type. Subsequently, sellar MRI was performed, and images showed a small non-enhancing heterogenous cystic lesion in the midline of the pituitary gland, radiologically suggestive of a Rathke's cleft cyst. However, sellar MRI failed to identify a lesion consistent with a pituitary tumor that corresponded to the site of increased FDG uptake detected by the use of PET, despite the inclusion of a dynamic contrast enhanced sequence. Despite the negative findings of the MRI examination, basal and stimulated levels of the GnRH free alpha-subunit were profoundly increased. Therefore, we suspected the presence of a non-functional pituitary tumor in addition to a Rathke's cleft cyst, rather than pituitary involvement of a lymphoma, based on the hormone levels and PET scan findings.

Citations

Citations to this article as recorded by

Clinical Characteristics of 16 Patients with Pituitary Tumor Incidentally Detected by18F-Fluorodeoxyglucose PET-CT (18F-FDG PET-CT)
Hyung Jin Kim, Gi Jeong Cheon, A Ra Cho, Chang Hoon Lee, Sang Min Youn, Se jin Ahn, Sang Eon Jang, Jung Min Kim, Yun Yong Lee, Ka Hee Yi
Endocrinology and Metabolism.2010; 25(4): 321. CrossRef

A Case of Lymphocytic Infundibuloneurohypophysitis Along with Central Diabetes Insipidus, and this Improved with Conservative Care.: Ji Myoung Lee, Sang Mi Park, Byung Hee Hwang, Hyun Sook Choi, Seong Su Lee, Jee Young Kim, Sung Rae Kim, Kwang Woo Lee, Ho Young Son, Sung Koo Kang, Soon Jib Yoo; J Korean Endocr Soc. 2008;23(2):142-147. Published online April 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.2.142

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Abstract PDF: Idiopathic central diabetes insipidus is most likely to occur in young patients who have a clinical history of autoimmune disease. The presentation of clinical findings such as central diabetes insipidus and pituitary stalk thickening on sellar magnetic resonance imaging (MRI) in a young women would strongly suggest lymphocytic hypophysitis, which is a rare inflammatory process involving the pituitary stalk and the pituitary gland, yet this disease can sometimes regress.

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