- Thyroid
- Immunoglobulin G4-Related Thyroid Disease: A Single-Center Experience and Literature Review
-
Meihua Jin, Bictdeun Kim, Ahreum Jang, Min Ji Jeon, Young Jun Choi, Yu-Mi Lee, Dong Eun Song, Won Gu Kim
-
Endocrinol Metab. 2022;37(2):312-322. Published online April 25, 2022
-
DOI: https://doi.org/10.3803/EnM.2021.1318
-
-
Abstract
PDF PubReader ePub Crossref - TDM
- Background
Immunoglobulin G4 (IgG4)-related disease is an entity that can involve the thyroid gland. The spectrum of IgG4-related thyroid disease (IgG4-RTD) includes Hashimoto thyroiditis (HT) and its fibrotic variant, Riedel thyroiditis, as well as Graves’ disease. The early diagnosis of IgG4-RTD is important because it is a medically treatable disease, and a delay in the diagnosis might result in unnecessary surgery. We present a case series of IgG4-RTD with a review of the literature.
Methods We retrospectively reviewed the clinical presentation and the radiological and pathological findings of patients diagnosed with IgG4-RTD between 2017 and 2021 at a tertiary medical center in Korea. We also conducted a literature review of IgG4-RTD.
Results Five patients were diagnosed with IgG4-RTD during the study period. The patients’ age ranged from 31 to 76 years, and three patients were men. Most patients visited the clinic for a neck mass, and hypoechogenic nodular lesions were observed on neck ultrasonography. Three patients had IgG4 HT, and two patients had IgG4 Riedel thyroiditis. All patients developed hypothyroidism that necessitated L-thyroxine replacement. The diagnosis of IgG4-RTD was confirmed after a pathological examination of the surgical specimen in the first two cases. However, the early diagnosis was possible after a core needle biopsy in three clinically suspected patients.
Conclusion The diagnosis of IgG4-RTD requires clinical suspicion combined with serology and histological analyses using IgG4 immunostaining. The early diagnosis of IgG4-RTD is difficult; thus, biopsy with IgG4 immunostaining and serum IgG4 measurements will help diagnose patients suspected of having IgG4-RTD.
- Clinical Study
- Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis
-
Se Jin Cho, Jung Hwan Baek, Sae Rom Chung, Young Jun Choi, Jeong Hyun Lee
-
Endocrinol Metab. 2020;35(2):339-350. Published online June 24, 2020
-
DOI: https://doi.org/10.3803/EnM.2020.35.2.339
-
-
8,377
View
-
257
Download
-
25
Citations
-
Abstract
PDF Supplementary Material PubReader ePub Crossref - TDM
- Background
Ultrasound-guided thermal ablations have become one of the main options for treating benign thyroid nodules. To determine efficacy of thermal ablation of benign thyroid nodules, we performed a meta-analysis of studies with long-term follow-up of more than 3 years.
Methods Databases were searched for studies published up to August 25, 2019, reporting patients with benign thyroid nodules treated with thermal ablation and with follow-up data of more than 3 years. Data extraction and quality assessment were performed according to PRISMA guidelines. The analysis yielded serial volume reduction rates (VRRs) of ablated nodules for up to 3 years or more, and adverse effect of ablation during follow-up. Radiofrequency ablation (RFA) and laser ablation (LA) were compared in a subgroup analysis.
Results The pooled VRRs for ablated nodules showed rapid volume reduction before 12 months, a plateau from 12 to 36 months, and more volume reduction appearing after 36 months, demonstrating long-term maintenance of treatment efficacy. Thermal ablation had an acceptable complication rate of 3.8%. Moreover, patients undergoing nodule ablation showed no unexpected delayed complications during the follow-up period. In the subgroup analysis, RFA was shown to be superior to LA in terms of the pooled VRR and the number of patients who underwent delayed surgery.
Conclusion Thermal ablations are safe and effective methods for treating benign thyroid nodules, as shown by a long follow-up analysis of more than 3 years. In addition, RFA showed superior VRRs compared with LA for the treatment of benign thyroid nodules, with less regrowth and less delayed surgery.
-
Citations
Citations to this article as recorded by 
- Ultrasound imaging in thyroid nodule diagnosis, therapy, and follow‐up: Current status and future trends
Tim Boers, Sicco J. Braak, Nicole E. T. Rikken, Michel Versluis, Srirang Manohar Journal of Clinical Ultrasound.2023;[Epub] CrossRef - A comprehensive review of interventional ablation techniques for the management of thyroid nodules and metastatic lymph nodes
Jennifer H. Kuo, Catherine F. Sinclair, Brian Lang, Stefano Spiezia, Mingan Yu, Eun Ju Ha, Dong Gyu Na, Chiara Offi, Kepal N. Patel, Jung Hwan Baek Surgery.2022; 171(4): 920. CrossRef -
Radiofrequency ablation and related
ultrasound‐guided
ablation technologies for treatment of benign and malignant thyroid disease: An international multidisciplinary consensus statement of the American Head and Neck So
Lisa A. Orloff, Julia E. Noel, Brendan C. Stack, Marika D. Russell, Peter Angelos, Jung Hwan Baek, Kevin T. Brumund, Feng‐Yu Chiang, Mary Beth Cunnane, Louise Davies, Andrea Frasoldati, Anne Y. Feng, Laszlo Hegedüs, Ayaka J. Iwata, Emad Kandil, Jennifer K Head & Neck.2022; 44(3): 633. CrossRef - Assessment of thyroid-specific quality of life in patients with benign symptomatic thyroid nodules treated with radiofrequency or ethanol ablation: a prospective multicenter study
So Yeong Jeong, Eun Ju Ha, Jung Hwan Baek, Tae Yong Kim, Yu-Mi Lee, Jeong Hyun Lee, Jeonghun Lee Ultrasonography.2022; 41(1): 204. CrossRef - Thyroid Nodule Radiofrequency Ablation: Complications and Clinical Follow Up
James Y. Lim, Jennifer H. Kuo Techniques in Vascular and Interventional Radiology.2022; 25(2): 100824. CrossRef - Radiofrequency Ablation of Solid, Non-Functional Thyroid Nodules
Michael Douek Techniques in Vascular and Interventional Radiology.2022; 25(2): 100821. CrossRef - Efficacy and Safety of Thermal Ablation for Treating Lymph Node Metastasis From Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis
Zheng Ding, Juan Chen, Zhiguang Chen, Xiaoke Zeng, Pengchao Zheng, Xuemei Wang, Xinwu Cui, Liang Sang Frontiers in Oncology.2022;[Epub] CrossRef - Intraoperative Neuromonitoring: Evaluating the Role of Continuous IONM and IONM Techniques for Emerging Surgical and Percutaneous Procedures
Catherine McManus, Jennifer Hong Kuo Frontiers in Endocrinology.2022;[Epub] CrossRef - Thermal Ablation for the Management of Papillary Thyroid Microcarcinoma in the Era of Active Surveillance and Hemithyroidectomy
Sae Rom Chung, Jung Hwan Baek, Young Jun Choi, Jeong Hyun Lee Current Oncology Reports.2022; 24(8): 1045. CrossRef - enhanced anarchic society optimization technique for the classification of ultrasound thyroid images using ILBP
D. Anitha, S. Sathya Priya International journal of health sciences.2022; : 4713. CrossRef - Image-Guided Percutaneous Ablation for Primary and Metastatic Tumors
Arian Mansur, Tushar Garg, Apurva Shrigiriwar, Vahid Etezadi, Christos Georgiades, Peiman Habibollahi, Timothy C. Huber, Juan C. Camacho, Sherif G. Nour, Alan Alper Sag, John David Prologo, Nariman Nezami Diagnostics.2022; 12(6): 1300. CrossRef - Efficacy and safety of ultrasound-guided microwave ablation versus surgical resection for Bethesda category IV thyroid nodules: A retrospective comparative study
Jingjing Yang, Ya Zhang, Xingjia Li, Yueting Zhao, Xue Han, Guofang Chen, Xiaoqiu Chu, Ruiping Li, Jianhua Wang, Fei Huang, Chao Liu, Shuhang Xu Frontiers in Endocrinology.2022;[Epub] CrossRef - Long-term follow-up of the radiofrequency ablation of benign thyroid nodules: the value of additional treatment
Hyun Jin Kim, Jung Hwan Baek, Woojin Cho, Jung Suk Sim Ultrasonography.2022; 41(4): 661. CrossRef - Das „heiße“ Schilddrüsenkarzinom mit einem kritischen Blick auf die Thermoablation
Joachim Jähne, Andreas Niesen, Joachim Bernhardts, Marija Hillemans Der Chirurg.2021; 92(1): 34. CrossRef - Current Practice of Percutaneous Ablation Technologies for Thyroid Nodules 2020
Haris Muhammad, Jonathon O. Russell, Prasanna Santhanam, Aniqa Tehreem, Ralph P. Tufano Current Otorhinolaryngology Reports.2021; 9(1): 52. CrossRef -
RFA
and benign thyroid nodules: Review of the current literature
Haris Muhammad, Prasanna Santhanam, Jonathon O. Russell, Jennifer H. Kuo Laryngoscope Investigative Otolaryngology.2021; 6(1): 155. CrossRef - Thermal Treatment Options for Benign Thyroid Nodules—The Role of Radio-Frequency Ablation and Laser Therapy
Erivelto Volpi Clinical Thyroidology.2021; 33(1): 17. CrossRef - Comparative efficacy of different ultrasound-guided ablation for the treatment of benign thyroid nodules: Systematic review and network meta-analysis of randomized controlled trials
Linye He, Wanjun Zhao, Zijing Xia, Anping Su, Zhihui Li, Jingqiang Zhu, Ivan D. Florez PLOS ONE.2021; 16(1): e0243864. CrossRef - Unresolved Clinical Issues in Thermal Ablation of Benign Thyroid Nodules: Regrowth at Long-Term Follow-Up
Jung Suk Sim, Jung Hwan Baek Korean Journal of Radiology.2021; 22(8): 1436. CrossRef - Current Status and Challenges of US-Guided Radiofrequency Ablation of Thyroid Nodules in the Long Term: A Systematic Review
Stella Bernardi, Andrea Palermo, Rosario Francesco Grasso, Bruno Fabris, Fulvio Stacul, Roberto Cesareo Cancers.2021; 13(11): 2746. CrossRef - Update of Radiofrequency Ablation for Treating Benign and Malignant Thyroid Nodules. The Future Is Now
Ralph P. Tufano, Pia Pace-Asciak, Jonathon O. Russell, Carlos Suárez, Gregory W. Randolph, Fernando López, Ashok R. Shaha, Antti Mäkitie, Juan P. Rodrigo, Luiz Paulo Kowalski, Mark Zafereo, Peter Angelos, Alfio Ferlito Frontiers in Endocrinology.2021;[Epub] CrossRef - Factors Associated with the Efficacy of Radiofrequency Ablation in the Treatment of Benign Thyroid Nodules
Huynh Q Khanh, Nguyen L Vuong, Tran Q Tien World Journal of Endocrine Surgery.2021; 12(3): 117. CrossRef - Long-Term Outcomes of Thermal Ablation for Benign Thyroid Nodules: The Issue of Regrowth
Jung Suk Sim, Jung Hwan Baek, Rosaria Meccariello International Journal of Endocrinology.2021; 2021: 1. CrossRef - Matrix 3D ultrasound-assisted thyroid nodule volume estimation and radiofrequency ablation: a phantom study
T. Boers, S. J. Braak, M. Versluis, S. Manohar European Radiology Experimental.2021;[Epub] CrossRef - Learning curve analysis of radiofrequency ablation for benign thyroid nodules
Chi-Yu Kuo, Chien-Liang Liu, Chung-Hsin Tsai, Shih-Ping Cheng International Journal of Hyperthermia.2021; 38(1): 1536. CrossRef
- Clinical Study
- Effectiveness of Injecting Cold 5% Dextrose into Patients with Nerve Damage Symptoms during Thyroid Radiofrequency Ablation
-
Min Kyoung Lee, Jung Hwan Baek, Sae Rom Chung, Young Jun Choi, Yu-Mi Lee, Tae Yong Kim, Jeong Hyun Lee
-
Endocrinol Metab. 2020;35(2):407-415. Published online June 24, 2020
-
DOI: https://doi.org/10.3803/EnM.2020.35.2.407
-
-
4,903
View
-
113
Download
-
9
Citations
-
Abstract
PDF PubReader ePub Crossref - TDM
- Background
Although radiofrequency ablation (RFA) is a safe treatment for thyroid tumors, nerve damage is a frequent complication. A previous retrospective study suggested that an injection of cold 5% dextrose in water (5% DW) can reduce nerve damage during RFA. This study validated the efficacy of injecting cold 5% DW for management of nerve damage during RFA.
Methods Between November 2017 and December 2018, 242 patients underwent 291 RFA sessions for treatment of benign thyroid nodules or recurrent thyroid cancers. Using a standardized technique, cold (0°C to 4°C) 5% DW was immediately injected around the damaged nerve into patients with any symptoms suggesting nerve damage. The incidence of nerve damage, the volume of 5% DW injected, symptom recovery time and the incidence of permanent nerve damage were evaluated.
Results Nineteen patients experienced nerve damage symptoms related to 21 RFA sessions, including 17 patients during 19 sessions and two patients on the day after two sessions. Patients with nerve damage symptoms detected during RFA were treated by injection of a mean 41 mL (range, 3 to 260) cold 5% DW, but the two patients who experienced symptoms the next day did not receive cold 5% DW injections. Immediate recovery was observed after 15 RFA sessions in 14 patients. No patient experienced permanent nerve damage.
Conclusion Injection of cold 5% DW is effective in managing nerve damage during RFA of thyroid lesions.
-
Citations
Citations to this article as recorded by 
- Clinical and Economic Evaluation of Ultrasound-Guided Radiofrequency Ablation vs. Parathyroidectomy for Patients with Primary Hyperparathyroidism: A Cohort Study
Hui-hui Chai, Zhan-jing Dai, Bai Xu, Qiao-hong Hu, Hong-feng He, Ying Xin, Wen-wen Yue, Cheng-zhong Peng Academic Radiology.2023;[Epub] CrossRef - Assessment of thyroid-specific quality of life in patients with benign symptomatic thyroid nodules treated with radiofrequency or ethanol ablation: a prospective multicenter study
So Yeong Jeong, Eun Ju Ha, Jung Hwan Baek, Tae Yong Kim, Yu-Mi Lee, Jeong Hyun Lee, Jeonghun Lee Ultrasonography.2022; 41(1): 204. CrossRef - Management of Recurrent Laryngeal Nerve Injury During Radiofrequency Ablation of Thyroid Nodules
Jules Aljammal, Iram Hussain, Shahzad Ahmad AACE Clinical Case Reports.2022; 8(2): 102. CrossRef - Thermal Ablation for the Management of Papillary Thyroid Microcarcinoma in the Era of Active Surveillance and Hemithyroidectomy
Sae Rom Chung, Jung Hwan Baek, Young Jun Choi, Jeong Hyun Lee Current Oncology Reports.2022; 24(8): 1045. CrossRef - Improving Voice Outcomes after Thyroid Surgery and Ultrasound-Guided Ablation Procedures
Pia Pace-Asciak, Jon O. Russell, Ralph P. Tufano Frontiers in Surgery.2022;[Epub] CrossRef - Using Intra-Operative Laryngeal Ultrasonography as a Real-Time Tool in Assessing Vocal Cord Function During Radiofrequency Ablation of the Thyroid Gland
Matrix Man Him Fung, Brian Hung Hin Lang World Journal of Surgery.2022; 46(9): 2206. CrossRef - Long-term outcome of microwave ablation for benign thyroid nodules: Over 48-month follow-up study
Jia-Rui Du, Wen-Hui Li, Cheng-Hai Quan, Hui Wang, Deng-Ke Teng Frontiers in Endocrinology.2022;[Epub] CrossRef - Continuous neuromonitoring during radiofrequency ablation of benign thyroid nodules provides objective evidence of laryngeal nerve safety
Catherine F. Sinclair, Maria J. Téllez, Roberto Peláez-Cruz, Alba Díaz-Baamonde, Sedat Ulkatan The American Journal of Surgery.2021; 222(2): 354. CrossRef - Future Considerations and Directions for Thermal Ablative Technologies
Jonathon Russell, Catherine F. Sinclair Current Otorhinolaryngology Reports.2021; 9(2): 210. CrossRef
- Clinical Study
- Does Radiofrequency Ablation Induce Neoplastic Changes in Benign Thyroid Nodules: A Preliminary Study
-
Su Min Ha, Jun Young Shin, Jung Hwan Baek, Dong Eun Song, Sae Rom Chung, Young Jun Choi, Jeong Hyun Lee
-
Endocrinol Metab. 2019;34(2):169-178. Published online May 15, 2019
-
DOI: https://doi.org/10.3803/EnM.2019.34.2.169
-
-
4,251
View
-
66
Download
-
18
Citations
-
Abstract
PDF Supplementary Material PubReader ePub Crossref - TDM
- Background
To evaluate the clinical feasibility of radiofrequency ablation (RFA) of benign thyroid nodules along with cytomorphological alteration, and any malignant transformation through biopsy. MethodsThe data were retrospectively collected between April 2008 and June 2013 and core needle biopsy (CNB) was performed on 16 benign thyroid nodules previously treated using RFA. The parameters of the patients were compared, between the time of enrollment and the last follow-up examination, using linear mixed model statistical analysis. ResultsNo atypical cells or neoplastic transformation were detected in the undertreated peripheral portion of treated benign nodules on the CNB specimen. RFA altered neither the thyroid capsule nor the thyroid tissue adjacent to the treated area. On histopathological examinations, we observed 81.2% acellular hyalinization, which was the most common finding. After a mean follow-up period of over 5 years, the mean volume of thyroid nodule had decreased to 6.4±4.2 mL, with a reduction rate of 81.3%±5.8% (P<0.0001). ConclusionRFA is a technically feasible treatment method for benign thyroid nodules, with no carcinogenic effect or tissue damage of the normal thyroid tissue adjacent to the RFA-treated zone.
-
Citations
Citations to this article as recorded by 
- Thermoablation of thyroid nodules reveals excellent results with low morbidity
Robert M. Eisele, Philipp R. Scherber, Monika Schlüter, Thorsten Drews, Matthias Glanemann, Gereon Gäbelein Technology and Health Care.2022; 30(3): 683. CrossRef -
Radiofrequency ablation and related
ultrasound‐guided
ablation technologies for treatment of benign and malignant thyroid disease: An international multidisciplinary consensus statement of the American Head and Neck So
Lisa A. Orloff, Julia E. Noel, Brendan C. Stack, Marika D. Russell, Peter Angelos, Jung Hwan Baek, Kevin T. Brumund, Feng‐Yu Chiang, Mary Beth Cunnane, Louise Davies, Andrea Frasoldati, Anne Y. Feng, Laszlo Hegedüs, Ayaka J. Iwata, Emad Kandil, Jennifer K Head & Neck.2022; 44(3): 633. CrossRef - Thyroid Nodule Radiofrequency Ablation: Complications and Clinical Follow Up
James Y. Lim, Jennifer H. Kuo Techniques in Vascular and Interventional Radiology.2022; 25(2): 100824. CrossRef - American Association of Clinical Endocrinology Disease State Clinical Review: The Clinical Utility of Minimally Invasive Interventional Procedures in the Management of Benign and Malignant Thyroid Lesions
Sina Jasim, Kepal N. Patel, Gregory Randolph, Stephanie Adams, Roberto Cesareo, Edward Condon, Tara Henrichsen, Malak Itani, Maria Papaleontiou, Leonardo Rangel, John Schmitz, Marius N. Stan Endocrine Practice.2022; 28(4): 433. CrossRef - Efficacy of radiofrequency and laser thermal ablation in solving thyroid nodule-related symptoms and cosmetic concerns. A systematic review and meta-analysis
Roberto Cesareo, Silvia Egiddi, Anda M. Naciu, Gaia Tabacco, Andrea Leoncini, Nicola Napoli, Andrea Palermo, Pierpaolo Trimboli Reviews in Endocrine and Metabolic Disorders.2022; 23(5): 1051. CrossRef - Comparison of ultrasound-guided radiofrequency ablation versus thyroid lobectomy for T1bN0M0 papillary thyroid carcinoma
Lin Yan, Xinyang Li, Yingying Li, Jing Xiao, Mingbo Zhang, Yukun Luo European Radiology.2022; 33(1): 730. CrossRef - A systematic review and meta-analysis comparing tumor progression and complications between radiofrequency ablation and thyroidectomy for papillary thyroid carcinoma
Yuan-dong Sun, Hao Zhang, Hai-tao Zhu, Chun-xue Wu, Miao-ling Chen, Jian-jun Han Frontiers in Oncology.2022;[Epub] CrossRef -
RFA
and benign thyroid nodules: Review of the current literature
Haris Muhammad, Prasanna Santhanam, Jonathon O. Russell, Jennifer H. Kuo Laryngoscope Investigative Otolaryngology.2021; 6(1): 155. CrossRef - Radiofrequency ablation and thyroid nodules: updated systematic review
Haris Muhammad, Prasanna Santhanam, Jonathon O. Russell Endocrine.2021; 72(3): 619. CrossRef - Complications of RFA for Thyroid Nodules: Prevention and Management
Rahul K. Sharma, Jennifer H Kuo Current Otorhinolaryngology Reports.2021; 9(1): 79. CrossRef - Long-Term Results of Ultrasound-Guided Radiofrequency Ablation of Benign Thyroid Nodules: State of the Art and Future Perspectives—A Systematic Review
Hervé Monpeyssen, Ahmad Alamri, Adrien Ben Hamou Frontiers in Endocrinology.2021;[Epub] CrossRef - Long-Term Outcomes of Thermal Ablation for Benign Thyroid Nodules: The Issue of Regrowth
Jung Suk Sim, Jung Hwan Baek, Rosaria Meccariello International Journal of Endocrinology.2021; 2021: 1. CrossRef - Ultrasound-Guided Radiofrequency Ablation Versus Thyroid Lobectomy for Low-Risk Papillary Thyroid Microcarcinoma: A Propensity-Matched Cohort Study of 884 Patients
Lin Yan, Mingbo Zhang, Qing Song, Yukun Luo Thyroid.2021; 31(11): 1662. CrossRef - Clinical Effects of Microwave Ablation in the Treatment of Low-Risk Papillary Thyroid Microcarcinomas and Related Histopathological Changes
Chenya Lu, Xingjia Li, Xiaoqiu Chu, Ruiping Li, Jie Li, Jianhua Wang, Yalin Wang, Yang Xu, Guofang Chen, Shuhang Xu, Chao Liu Frontiers in Endocrinology.2021;[Epub] CrossRef - Ultrasound-Guided Thermal Ablation of Thyroid Nodules: Technicalities Progress and Clinical Applications, Especially in Malignant Thyroid Nodules
Enock Adjei Agyekum, Jian-hua Fu, Fei-Ju Xu, Yong-Zhen Ren, Debora Akortia, Qing Chen, Xiao-Qin Qian, Yuguo Wang, Xian Wang Frontiers in Oncology.2021;[Epub] CrossRef - Comparison Between Radiofrequency Ablation and Microwave Ablation in the Treatment for Benign Thyroid Nodules: a Meta-analysis
Jing Wu, Junguo Liu, Li Liu Indian Journal of Surgery.2021;[Epub] CrossRef - 2020 European Thyroid Association Clinical Practice Guideline for the Use of Image-Guided Ablation in Benign Thyroid Nodules
Enrico Papini, Hervé Monpeyssen, Andrea Frasoldati, Laszlo Hegedüs European Thyroid Journal.2020; 9(4): 172. CrossRef - Response: Long-Term Outcomes Following Thermal Ablation of Benign Thyroid Nodules as an Alternative to Surgery: The Importance of Controlling Regrowth (Endocrinol Metab 2019;34:117–23, Jung Suk Sim et al.)
Jung Suk Sim, Jung Hwan Baek Endocrinology and Metabolism.2019; 34(3): 325. CrossRef
- A Comparison of Ultrasound-Guided Fine Needle Aspiration versus Core Needle Biopsy for Thyroid Nodules: Pain, Tolerability, and Complications
-
Eun Ji Jeong, Sae Rom Chung, Jung Hwan Baek, Young Jun Choi, Jae Kyun Kim, Jeong Hyun Lee
-
Endocrinol Metab. 2018;33(1):114-120. Published online March 21, 2018
-
DOI: https://doi.org/10.3803/EnM.2018.33.1.114
-
-
4,022
View
-
47
Download
-
17
Citations
-
Abstract
PDF PubReader ePub Crossref - TDM
- Background
To compare pain, tolerability, and complications associated with fine needle aspiration (FNA) versus core needle biopsy (CNB). MethodsFNAs were performed using 23-gauge needles and CNBs were performed using 18-gauge double-action spring-activated needles in 100 patients for each procedure. Patients were asked to record a pain score using a 10-cm visual analog scale and procedure tolerability. Complications and number of biopsies were recorded. ResultsThe median pain scores were similar for the FNA and CNB approaches during and 20 minutes after the biopsy procedures (3.7 vs. 3.6, P=0.454; 0.9 vs. 1.1, P=0.296, respectively). The procedure was tolerable in all 100 FNA patients and in 97 CNB patients (P=0.246). The mean number of biopsies was fewer in the CNB group (1.4 vs. 1.2, P=0.002). By subgroup analysis (staff vs. non-staff), no significant difference was detected in any parameter. There were no major complications in either group, but three patients who underwent CNB had minor complications (P=0.246). ConclusionFNA and CNB show no significant differences for diagnosing thyroid nodules in terms of pain, tolerability, or complications.
-
Citations
Citations to this article as recorded by 
- Utilidad de la biopsia con aguja gruesa ecoguiada en nódulos tiroideos con punción aspirativa con aguja fina no diagnóstica
R. Cortázar-García, M.D. Martín-Escalante, L. Robles-Cabeza, C. Martínez-Santos Radiología.2022; 64(3): 195. CrossRef - Thyroid diagnostic modalities (fine needle aspiration and core needle biopsy) with histology correlation: a tertiary centre experience
Sona J Appukutty, Anna Paterson, Nishant S Patel, Adam Duckworth, James Chan, Maria O'Donovan, Alison J Marker Journal of Clinical Pathology.2022; 75(9): 620. CrossRef - Diagnostic performance of core needle biopsy for nodal recurrences in patients with head and neck squamous cell carcinoma
Ta-Hsuan Lo, Cheng-Ping Wang, Chun-Nan Chen, Tsung-Lin Yang, Pei-Jen Lou, Jenq-Yuh Ko, Yih-Leong Chang, Tseng-Cheng Chen Scientific Reports.2022;[Epub] CrossRef - The efficacy of incorporating ultrasound-guided core biopsy into the clinical workflow of indeterminate thyroid tumors
Chun-Nan Chen, Min-Shu Hsieh, Yi-Hsuan Lee, Tsung-Lin Yang Journal of the Formosan Medical Association.2022; 121(10): 2012. CrossRef - A Literature Review of Factors Associated With Pain From Fine Needle Aspiration Biopsy of Thyroid Nodules
Tao Liu, Manisha Tilak, Sara Awad, Joshua Lakoff Endocrine Practice.2022; 28(6): 628. CrossRef - Usefulness of ultrasound-guided core biopsy in thyroid nodules with inconclusive fine-needle aspiration biopsy findings
R. Cortázar-García, M.D. Martín-Escalante, L. Robles-Cabeza, C. Martínez-Santos Radiología (English Edition).2022; 64(3): 195. CrossRef - Permanent vocal fold paralysis after ultrasound-guided core needle biopsy of thyroid nodule
Kathrin Zimmerman, Matthew Hoffman, Amalee Smith, C. Blake Simpson Otolaryngology Case Reports.2022; 24: 100455. CrossRef - Interobserver variability in ultrasound assessment of thyroid nodules
Jaber Alyami, Fahad F. Almutairi, Sultan Aldoassary, Amani Albeshry, Ali Almontashri, Mazen Abounassif, Majed Alamri Medicine.2022; 101(41): e31106. CrossRef - Usage and Diagnostic Yield of Fine-Needle Aspiration Cytology and Core Needle Biopsy in Thyroid Nodules: A Systematic Review and Meta-Analysis of Literature Published by Korean Authors
Soon-Hyun Ahn Clinical and Experimental Otorhinolaryngology.2021; 14(1): 116. CrossRef - Hydrodissection: A Novel Approach for Safe Core Needle Biopsy of Small High-Risk Subcapsular Thyroid Nodules
Hojat Ebrahiminik, Hossein Chegeni, Javad Jalili, Rambod Salouti, Hadi Rokni, Afshin Mohammadi, Ali Mosaddegh Khah, Seyed Mohammad Tavangar, Zahra Ebrahiminik CardioVascular and Interventional Radiology.2021; 44(10): 1651. CrossRef - A Blinded Randomized Trial Comparing 2 Needle Gauges for Fine‐Needle Biopsy of Thyroid Nodules
Christopher M. Shumrick, Jonathan C. Simmonds, Lorna L. Ogden, Cindi A. Snowden, Jagdish K. Dhingra OTO Open.2021;[Epub] CrossRef - Application of biomarkers in the diagnosis of uncertain samples of core needle biopsy of thyroid nodules
Yan Xiong, Xin Li, Li Liang, Dong Li, Limin Yan, Xueying Li, Jiting Di, Ting Li Virchows Archiv.2021; 479(5): 961. CrossRef - Diagnostic Efficacy and Safety of Core Needle Biopsy as a First-Line Diagnostic Method for Thyroid Nodules: A Prospective Cohort Study
Min Ji Hong, Dong Gyu Na, Hunkyung Lee Thyroid.2020; 30(8): 1141. CrossRef - Comparison Between Fine Needle Aspiration and Core Needle Biopsy for the Diagnosis of Thyroid Nodules: Effective Indications According to US Findings
Soo Yeon Hahn, Jung Hee Shin, Young Lyun Oh, Ko Woon Park, Yaeji Lim Scientific Reports.2020;[Epub] CrossRef - 2019 Practice guidelines for thyroid core needle biopsy: a report of the Clinical Practice Guidelines Development Committee of the Korean Thyroid Association
Chan Kwon Jung, Jung Hwan Baek, Dong Gyu Na, Young Lyun Oh, Ka Hee Yi, Ho-Cheol Kang Journal of Pathology and Translational Medicine.2020; 54(1): 64. CrossRef - Pathological diagnosis of thyroid nodules based on core needle biopsies: comparative study between core needle biopsies and resected specimens in 578 cases
Yan Xiong, Limin Yan, Lin Nong, Yalin Zheng, Ting Li Diagnostic Pathology.2019;[Epub] CrossRef - The Significance of Having an Excellent Patient's Comfort with Thyroid Core Needle Biopsy
Pierpaolo Trimboli, Luca Giovanella Endocrinology and Metabolism.2018; 33(1): 53. CrossRef
|