- Diabetes, Obesity and Metabolism
- Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones
-
Bo Hye Kim, Yena Joo, Min-Seon Kim, Han Kyoung Choe, Qingchun Tong, Obin Kwon
-
Endocrinol Metab. 2021;36(4):745-756. Published online August 27, 2021
-
DOI: https://doi.org/10.3803/EnM.2021.405
-
-
15,167
View
-
745
Download
-
17
Citations
-
 Abstract
 PDF PubReader  ePub  Crossref - TDM
- Intermittent fasting has become an increasingly popular strategy in losing weight and associated reduction in obesity-related medical complications. Overwhelming studies support metabolic improvements from intermittent fasting in blood glucose levels, cardiac and brain function, and other health benefits, in addition to weight loss. However, concerns have also been raised on side effects including muscle loss, ketosis, and electrolyte imbalance. Of particular concern, the effect of intermittent fasting on hormonal circadian rhythms has received little attention. Given the known importance of circadian hormonal changes to normal physiology, potential detrimental effects by dysregulation of hormonal changes deserve careful discussions. In this review, we describe the changes in circadian rhythms of hormones caused by intermittent fasting. We covered major hormones commonly pathophysiologically involved in clinical endocrinology, including insulin, thyroid hormones, and glucocorticoids. Given that intermittent fasting could alter both the level and frequency of hormone secretion, decisions on practicing intermittent fasting should take more considerations on potential detrimental consequences versus beneficial effects pertaining to individual health conditions.
-
Citations
Citations to this article as recorded by  - Fasting intervention and its clinical effects on the human host and microbiome
Sofia K. Forslund
Journal of Internal Medicine.2023; 293(2): 166. CrossRef - Umbrella review of time-restricted eating on weight loss, fasting blood glucose, and lipid profile
Han Shi Jocelyn Chew, Wei How Darryl Ang, Zhen Yang Abel Tan, Wen Wei Ang, Kin Sun Chan, Ying Lau
Nutrition Reviews.2023; 81(9): 1180. CrossRef - Thermodynamic Assessment of the Effects of Intermittent Fasting and Fatty Liver Disease Diets on Longevity
Melek Ece Öngel, Cennet Yildiz, Özge Başer, Bayram Yilmaz, Mustafa Özilgen
Entropy.2023; 25(2): 227. CrossRef - Effects of Intermittent Fasting on Hypothalamus–Pituitary–Thyroid Axis, Palatable Food Intake, and Body Weight in Stressed Rats
Cinthia García-Luna, Ixchel Prieto, Paulina Soberanes-Chávez, Elena Alvarez-Salas, Iván Torre-Villalvazo, Gilberto Matamoros-Trejo, Patricia de Gortari
Nutrients.2023; 15(5): 1164. CrossRef - Possible homeostatic, glucose uptake mechanisms and hepato-pancreatic histological effects of intermittent fasting, exercise, starvation, and honey in streptozotocin-induced diabetes in rats
Ejime A. Chijiokwu, Eze K. Nwangwa, Mega O. Oyovwi, Benneth Ben-Azu, Alexander O. Naiho, Emuesiri Goodies Moke, Victor Emojevwe, Prosper A. Ehiwarior, Udoka S. Nwabuoku
Nutrire.2023;[Epub] CrossRef - Mid-Point of the Active Phase Is Better to Achieve the Natriuretic Effect of Acute Salt Load in Mice
Momoko Imamura, Hiroyuki Sasaki, Katsuki Hayashi, Shigenobu Shibata
Nutrients.2023; 15(7): 1679. CrossRef - All That Glitters Is Not Gold: The Same Sleep Time, but Different Diabetogenic Outcomes
Bohye Kim, Obin Kwon
Endocrinology and Metabolism.2023; 38(1): 78. CrossRef - The emerging role of circadian rhythms in the development and function of thermogenic fat
Xuemin Peng, Yong Chen
Frontiers in Endocrinology.2023;[Epub] CrossRef - Time-restricted Feeding Changes as Inspiration for Drug Design
Zhangyuting He, Huayu Yang, Yilei Mao
Current Pharmaceutical Design.2023; 29(8): 559. CrossRef - Brain Dopamine–Clock Interactions Regulate Cardiometabolic Physiology: Mechanisms of the Observed Cardioprotective Effects of Circadian-Timed Bromocriptine-QR Therapy in Type 2 Diabetes Subjects
Anthony H. Cincotta
International Journal of Molecular Sciences.2023; 24(17): 13255. CrossRef - Adaptive Circadian Rhythms for Autonomous and Biologically Inspired Robot Behavior
Marcos Maroto-Gómez, María Malfaz, Álvaro Castro-González, Sara Carrasco-Martínez, Miguel Ángel Salichs
Biomimetics.2023; 8(5): 413. CrossRef - Intermittent fasting, high-intensity interval training, or a combination of both have beneficial effects in obese mice with nonalcoholic fatty liver disease
Patrícia de Castro-de-Paiva, Thatiany de Souza Marinho, Carlos Alberto Mandarim-de-Lacerda, Marcia Barbosa Aguila
The Journal of Nutritional Biochemistry.2022; 104: 108997. CrossRef - Optimal Timing of Thyroid Hormone Replacement During Ramadan Fasting: A Randomized Controlled Trial in Patients with Prior Total Thyroidectomy
Khalid M. Al-Qahtani, Ibraheem Ahmed Aldeeri, Amal M. Alshaibi, Norah Salman Alshabib, Rakan M. Barghouthi, Ebtihal Y. Alyusuf, Anwar Ali Jammah
Thyroid.2022; 32(9): 1029. CrossRef - Exploring the Effects of Energy Constraints on Performance, Body Composition, Endocrinological/Hematological Biomarkers, and Immune System among Athletes: An Overview of the Fasting State
Hadi Nobari, Saber Saedmocheshi, Eugenia Murawska-Ciałowicz, Filipe Manuel Clemente, Katsuhiko Suzuki, Ana Filipa Silva
Nutrients.2022; 14(15): 3197. CrossRef - Alternate day fasting and time-restricted feeding may confer similar neuroprotective effects during aging in male rats
Sukanya Bhoumik, Rashmi Kesherwani, Raushan Kumar, Syed Ibrahim Rizvi
Biogerontology.2022; 23(6): 757. CrossRef - Intermittent Fasting—A Healthy Dietary Pattern for Diabetic Nephropathy
Ming Yang, Wei Chen, Liyu He, Di Liu, Li Zhao, Xi Wang
Nutrients.2022; 14(19): 3995. CrossRef - β-hydroxybutyrate as an Anti-Aging Metabolite
Lian Wang, Peijie Chen, Weihua Xiao
Nutrients.2021; 13(10): 3420. CrossRef
|
KES
