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Endocrinol Metab : Endocrinology and Metabolism


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Sung Jin Hong  (Hong SJ) 1 Article
A Case of Graves' Disease Presenting with Chorea.
Cheol Ryong Ku, Hyung Jun Park, Sung Jin Hong, Dong Yeob Shin, Jin Ha Lee, Moon Jae Chung, Mi Ae Cho, Tae Woong Noh, Byung In Lee, Eun Jig Lee
J Korean Endocr Soc. 2008;23(5):342-346.   Published online October 1, 2008
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AbstractAbstract PDF
Hyperthyroidism is invariably accompanied by nervous system dysfunction. Specifically, irritability, emotional lability, and hyperkinesia are the signs and symptoms most frequently observed. In rare instances, chorea and/or choreoathetosis are associated with hyperthyroidism. Full evaluation for the etiology of chorea is necessary prior to initiating treatment. We recently encountered a 42-year-old female who initially presented with hyperthyroidism and showed subsequent development of progressive generalized chorea. The patient was diagnosed with chorea secondary to Graves' disease after exclusion of other causes of chorea and improved after the initiation of pulse administration of intravenous methylprednisolone sodium succinate (Solu-medrol(R), 1000 mg for 5 days) and oral antithyroid medication. This treatment strategy resulted in the resolution of involuntary movements. The steroid administration was eventually tapered, and the patient has been maintained on antithyroid and steroid therapy with considerable success since the initiation of treatment.


Citations to this article as recorded by  
  • Unilateral upper limb chorea associated with hyperthyroidism: A case report and literature review
    Wei Chen, Bin Wu, Hongna An, Kaiying Zheng, Daming Zhai, Jiahua Zang, Xiaobing Wu
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • Anti-Thyroid Peroxidase/Anti-Thyroglobulin Antibody-Related Neurologic Disorder Responsive to Steroids Presenting with Pure Acute Onset Chorea
    Ritwik Ghosh, Subhankar Chatterjee, Souvik Dubey, Alak Pandit, Biman Kanti Ray, Julián Benito-León
    Tremor and Other Hyperkinetic Movements.2020;[Epub]     CrossRef
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