Endocrinology and Metabolism

Se Hyuk Kim (Kim SH)

3 Articles

Pituitary Hormonal Changes after Transsphenoidal Tumor Removal in Non-Functioning Pituitary Adenoma.: Min Suk Lee, Seung Jin Han, Eun Kyung Kim, Joo An Hwang, Yoon Sok Chung, Se Hyuk Kim, Kyung Gi Cho, Nae Jung Rim, Ho Sung Kim; J Korean Endocr Soc. 2009;24(3):181-188. Published online September 1, 2009; DOI: https://doi.org/10.3803/jkes.2009.24.3.181

1,873 View
23 Download
1 Crossref

BACKGROUND
The present study investigated the rates and the potential predictors of either new pituitary loss or recovery of hormonal function after transsphenoidal removal of a non-functioning pituitary adenoma. METHODS: Patients who underwent transsphenoidal removal of a non-functioning pituitary adenoma from January 2003 to December 2007 at Ajou University Medical Center were included in this retrospective analysis. Patients were excluded if they had a history of previous pituitary tumor surgery, or did not have preoperative pituitary hormonal data. RESULTS: Of 42 patients included in the analysis, 36 patients had hypopituitarism, 21 patients had "stalk compression" hyperprolactinemia, and 2 patients had normal pituitary function. At long term follow-up (longer than 6 months), 13 patients showed postoperative pituitary hormonal recovery in at least 1 hormonal axis, while 6 patients had developed postoperative hormonal loss in at least 1 hormonal axis. On analysis, neither preoperative serum prolactin level nor tumor size was related to postoperative pituitary hormonal changes. CONCLUSION: More than 1/3 of patients who underwent transsphenoidal surgery showed postoperative pituitary hormonal recovery.

Citations

Citations to this article as recorded by

Childhood Onset Pituitary Adenoma: Clinical Presentations and Outcomes of 24 Cases
Hwa Young Kim, Hae Woon Jung, Jieun Lee, Ju Young Yoon, Young Ah Lee, Choong Ho Shin, Sei Won Yang
Annals of Pediatric Endocrinology & Metabolism.2012; 17(2): 82. CrossRef

A Case of Panhypopituitarism and Central Diabetes Insipidus Caused by Primary Central Nervous System Lymphoma.: Mi Sun Ahn, Soon Sun Kim, Tae Ho Kim, Seung Jin Han, Dae Jung Kim, Hugh Chul Kim, Se Hyuk Kim, Jae Ho Han, Ho Sung Kim, Yoon Sok Chung; J Korean Endocr Soc. 2008;23(4):260-265. Published online August 1, 2008; DOI: https://doi.org/10.3803/jkes.2008.23.4.260

1,898 View
22 Download

Abstract PDF: Primary central nervous system (CNS) lymphoma is an uncommon neoplasm. However, the incidence of primary CNS lymphoma has increased more than 10-fold over the past three decades, and continues to accelerate. Currently, primary CNS lymphoma represents 4 to 7 percent of all newly diagnosed primary CNS tumors. Primary CNS lymphoma may arise from different parts of the brain, with deep hemispheric periventricular white matter being the most common site of origin. The presenting symptoms in primary CNS lymphoma vary depending on the location of the mass. Involvement of the hypothalamic-pituitary axis may cause hypopituitarism, diabetes insipidus, headache, diplopia, and blurred vision.

The Endocrinological Characteristics of Rathke's Cleft Cyst: Pathologically Confirmed in Seven Cases.: Su Kyong Yu, Yun Kyung Kim, Hye Jin Kim, Dae Jung Kim, Yoon Sok Chung, Kwan Woo Lee, Se Hyuk Kim, Kyung Gi Cho; J Korean Endocr Soc. 2007;22(1):74-79. Published online February 1, 2007; DOI: https://doi.org/10.3803/jkes.2007.22.1.74

1,946 View
29 Download
1 Crossref

Abstract PDF

Rathke's cleft cyst is a cystic sellar or suprasellar lesion thought to originate from the remnants of Rathke's pouch. It is characteristically lined by a single layer of ciliated cuboidal or columnar epithelium. Although small asymptomatic Rathke's cleft cysts have been reported at autopsy in 2~26% of normal pituitary glands, symptomatic cysts are rare. For patients with symptomatic Rathke's cleft cysts presentation with headache, pituitary dysfunction, and visual loss caused by compression of the optic chiasm in the event of suprasellar extension, is common. We report the endocrine characteristics of seven cases of patients with symptomatic Rathke's cleft cyst diagnosed with pathologic confirmation.

Citations

Citations to this article as recorded by

Risk factor for pituitary dysfunction in children and adolescents with Rathke's cleft cysts
Han Hyuk Lim, Sei Won Yang
Korean Journal of Pediatrics.2010; 53(7): 759. CrossRef

Author index