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Kyung-Soo Kim  (Kim KS) 4 Articles
Diabetes, Obesity and Metabolism
The Clinical Characteristics of Gestational Diabetes Mellitus in Korea: A National Health Information Database Study
Kyung-Soo Kim, Sangmo Hong, Kyungdo Han, Cheol-Young Park
Endocrinol Metab. 2021;36(3):628-636.   Published online May 26, 2021
DOI: https://doi.org/10.3803/EnM.2020.948
  • 3,775 View
  • 132 Download
  • 4 Citations
AbstractAbstract PDFSupplementary MaterialPubReader   ePub   CrossRef-TDMCrossref - TDM
Background
To investigate the clinical characteristics of gestational diabetes mellitus (GDM) in Korea, using a nationwide database.
Methods
We analyzed 417,139 women who gave birth between 2011 and 2015 using the Korean National Health Information Database. They underwent the Korean National Health Screening Program within one year before pregnancy and were not prescribed drugs for diabetes nor diagnosed with diabetes mellitus before 280 days antepartum. Patients with GDM were defined as those who visited the outpatient clinic more than twice with GDM codes.
Results
The prevalence of GDM was 12.70% and increased with increasing maternal age, prepregnancy body mass index (BMI), waist circumference (WC), and fasting plasma glucose (FPG) (P for trend <0.05). As compared with those aged <25 years, the odds ratio for women with GDM aged ≥40 years were 4.804 (95% confidence interval [CI], 4.436 to 5.203) after adjustment for covariates. Women with prepregnancy BMI ≥30 kg/m2 were at 1.898 times (95% CI, 1.736 to 2.075) greater risk for GDM than those with prepregnancy BMI <18.5 kg/m2. Women with WC of ≥95 cm were at 1.158 times (95% CI, 1.029 to 1.191) greater risk for GDM than women with WC of less than 65 cm. High FPG, high income, smoking, and drinking were associated with an elevated risk of GDM.
Conclusion
The prevalence of GDM in Korean women increased up to 12.70% during 2011 to 2015. These data suggest the importance of GDM screening and prevention in high-risk groups in Korea.

Citations

Citations to this article as recorded by  
  • Gestational Diabetes Mellitus: Diagnostic Approaches and Maternal-Offspring Complications
    Joon Ho Moon, Hak Chul Jang
    Diabetes & Metabolism Journal.2022; 46(1): 3.     CrossRef
  • Current Trends of Big Data Research Using the Korean National Health Information Database
    Mee Kyoung Kim, Kyungdo Han, Seung-Hwan Lee
    Diabetes & Metabolism Journal.2022; 46(4): 552.     CrossRef
  • Maternal Gestational Diabetes Influences DNA Methylation in the Serotonin System in the Human Placenta
    Jae Yen Song, Kyung Eun Lee, Eun Jeong Byeon, Jieun Choi, Sa Jin Kim, Jae Eun Shin
    Life.2022; 12(11): 1869.     CrossRef
  • Fetal Abdominal Obesity Detected At 24 to 28 Weeks of Gestation Persists Until Delivery Despite Management of Gestational Diabetes Mellitus (Diabetes Metab J 2021;45:547-57)
    Kyung-Soo Kim
    Diabetes & Metabolism Journal.2021; 45(6): 966.     CrossRef
Clinical Study
Vitamin D Deficiency at Mid-Pregnancy Is Associated with a Higher Risk of Postpartum Glucose Intolerance in Women with Gestational Diabetes Mellitus
Kyung-Soo Kim, Seok Won Park, Yong-Wook Cho, Soo-Kyung Kim
Endocrinol Metab. 2020;35(1):97-105.   Published online March 19, 2020
DOI: https://doi.org/10.3803/EnM.2020.35.1.97
  • 4,053 View
  • 93 Download
  • 7 Citations
AbstractAbstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM
Background

To evaluate the association between serum 25-hydroxyvitamin D (25(OH)D) at mid-pregnancy and postpartum glucose intolerance in women with gestational diabetes mellitus (GDM).

Methods

We enrolled 348 pregnant women diagnosed with GDM from August 2012 to October 2016. We measured serum 25(OH)D levels at mid-pregnancy and carried out a 75-g oral glucose tolerance test at 6 to 12 weeks after delivery. Vitamin D deficiency was defined as serum 25(OH)D <20 ng/mL.

Results

The prevalence of vitamin D deficiency was 76.7% (n=267). Women with vitamin D deficiency had a higher prevalence of postpartum glucose intolerance than did those without vitamin D deficiency (48.7% vs. 32.1%, P=0.011). Serum 25(OH)D level was negatively correlated with hemoglobin A1c at antepartum and postpartum period (antepartum: r=−0.186, P=0.001; postpartum: r=−0.129, P=0.047). Homeostasis model assessment of β-cell function was positively correlated with serum 25(OH)D level only postpartum (r=0.138, P=0.035). The risk of postpartum glucose intolerance was 2.00 times (95% confidence interval, 1.13 to 3.55) higher in women with vitamin D deficiency than in those without vitamin D deficiency (P=0.018).

Conclusion

In women with GDM, vitamin D deficiency at mid-pregnancy is associated with an elevated risk of postpartum glucose intolerance.

Citations

Citations to this article as recorded by  
  • Vitamin D Supplementation for the Outcomes of Patients with Gestational Diabetes Mellitus and Neonates: A Meta-Analysis and Systematic Review
    Chunfeng Wu, Yang Song, Xueying Wang, Pier P. Sainaghi
    International Journal of Clinical Practice.2023; 2023: 1.     CrossRef
  • Influence of hypovitaminosis D during pregnancy on glycemic and lipid profile, inflammatory indicators and anthropometry of pregnant and newborn
    Sara de Figueiredo dos Santos, Paula Normando dos Reis Costa, Thaise Gasser Gouvêa, Nathalia Ferreira Antunes de Almeida, Felipe de Souza Cardoso
    Clinical Nutrition ESPEN.2023; 54: 81.     CrossRef
  • Postprandial Free Fatty Acids at Mid-Pregnancy Increase the Risk of Large-for-Gestational-Age Newborns in Women with Gestational Diabetes Mellitus
    So-Yeon Kim, Young Shin Song, Soo-Kyung Kim, Yong-Wook Cho, Kyung-Soo Kim
    Diabetes & Metabolism Journal.2022; 46(1): 140.     CrossRef
  • Effect of Evidence-Based Diet Nursing on Intestinal Flora and Maternal and Infant Prognosis in Patients with Gestational Diabetes
    Ying Jiang, Chunbo Qiu, Yuanping Wang, Bin He, Peng-Yue Zhang
    Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1.     CrossRef
  • Vitamin D in gestational diabetes: A broadened frontier
    Yu Zhu, Ling Li, Ping Li
    Clinica Chimica Acta.2022; 537: 51.     CrossRef
  • The Clinical Characteristics of Gestational Diabetes Mellitus in Korea: A National Health Information Database Study
    Kyung-Soo Kim, Sangmo Hong, Kyungdo Han, Cheol-Young Park
    Endocrinology and Metabolism.2021; 36(3): 628.     CrossRef
  • Fetal Abdominal Obesity Detected At 24 to 28 Weeks of Gestation Persists Until Delivery Despite Management of Gestational Diabetes Mellitus (Diabetes Metab J 2021;45:547-57)
    Kyung-Soo Kim
    Diabetes & Metabolism Journal.2021; 45(6): 966.     CrossRef
Clinical Study
Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
Seung Jin Han, Kyung-Soo Kim, Wonjin Kim, Jung Hee Kim, Yong-ho Lee, Ji Sun Nam, Ji A Seo, Bu Kyung Kim, Jihyun Lee, Jin Ook Chung, Min-Hee Kim, Tae-Seo Sohn, Han Seok Choi, Seong Bin Hong, Yoon-Sok Chung
Endocrinol Metab. 2016;31(4):598-603.   Published online December 20, 2016
DOI: https://doi.org/10.3803/EnM.2016.31.4.598
  • 4,320 View
  • 31 Download
  • 18 Citations
AbstractAbstract PDFPubReader   CrossRef-TDMCrossref - TDM
Background

The aim of this study was to investigate the prevalence of obesity in Korean men with Klinefelter syndrome (KS) and the associated risk factors for obesity and hyperglycemia.

Methods

Data were collected retrospectively from medical records from 11 university hospitals in Korea between 1994 and 2014. Subjects aged ≥18 years with newly diagnosed KS were enrolled. The following parameters were recorded at baseline before treatment: chief complaint, height, weight, fasting glucose level, lipid panel, blood pressure, testosterone, luteinizing hormone, follicle-stimulating hormone, karyotyping patterns, and history of hypertension, diabetes, and dyslipidemia.

Results

Data were analyzed from 376 of 544 initially enrolled patients. The rate of the 47 XXY chromosomal pattern was 94.1%. The prevalence of obesity (body mass index ≥25 kg/m2) in Korean men with KS was 42.6%. The testosterone level was an independent risk factor for obesity and hyperglycemia.

Conclusion

Obesity is common in Korean men with KS. Hypogonadism in patients with KS was associated with obesity and hyperglycemia.

Citations

Citations to this article as recorded by  
  • A dual-center study of predictive factors for sperm retrieval through microdissection testicular sperm extraction and intracytoplasmic sperm injection outcomes in men with non-mosaic Klinefelter syndrome
    Jong Hyeun Baeck, Tae Jin Kim, Tae Heon Kim, Seung-Ryeol Lee, Dong Soo Park, Hwang Kwon, Ji Eun Shin, Dong Hyeon Lee, Young Dong Yu
    Investigative and Clinical Urology.2023; 64(1): 41.     CrossRef
  • Cardiorespiratory fitness in adolescents and young adults with Klinefelter syndrome – a pilot study
    Julia Spiekermann, Kathrin Sinningen, Beatrice Hanusch, Michaela Kleber, Michael M. Schündeln, Cordula Kiewert, Heide Siggelkow, Jakob Höppner, Corinna Grasemann
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Metabolic Profile in a Cohort of Young Sicilian Patients with Klinefelter’s Syndrome: The Role of Irisin
    Stefano Radellini, Valentina Guarnotta, Vincenzo Sciabica, Giuseppe Pizzolanti, Carla Giordano, Vito Angelo Giagulli
    International Journal of Endocrinology.2022; 2022: 1.     CrossRef
  • Metabolic and Nutritional Aspects in Paediatric Patients with Klinefelter Syndrome: A Narrative Review
    Chiara Mameli, Giulia Fiore, Arianna Sangiorgio, Marta Agostinelli, Giulia Zichichi, Gianvincenzo Zuccotti, Elvira Verduci
    Nutrients.2022; 14(10): 2107.     CrossRef
  • Klinefelter syndrome in an adolescent with severe obesity, insulin resistance, and hyperlipidemia, successfully treated with testosterone replacement therapy
    Shota Fukuhara, Jun Mori, Hisakazu Nakajima
    Clinical Pediatric Endocrinology.2021; 30(3): 127.     CrossRef
  • Glucose metabolic disorder in Klinefelter syndrome: a retrospective analysis in a single Chinese hospital and literature review
    Shixuan Liu, Tao Yuan, Shuoning Song, Shi Chen, Linjie Wang, Yong Fu, Yingyue Dong, Yan Tang, Weigang Zhao
    BMC Endocrine Disorders.2021;[Epub]     CrossRef
  • What Every Internist-Endocrinologist Should Know about Rare Genetic Syndromes in Order to Prevent Needless Diagnostics, Missed Diagnoses and Medical Complications: Five Years of ‘Internal Medicine for Rare Genetic Syndromes’
    Anna G. W. Rosenberg, Minke R. A. Pater, Karlijn Pellikaan, Kirsten Davidse, Anja A. Kattentidt-Mouravieva, Rogier Kersseboom, Anja G. Bos-Roubos, Agnies van Eeghen, José M. C. Veen, Jiske J. van der Meulen, Nina van Aalst-van Wieringen, Franciska M. E. H
    Journal of Clinical Medicine.2021; 10(22): 5457.     CrossRef
  • Klinefelter Syndrome and Diabetes
    Mark J. O’Connor, Emma A. Snyder, Frances J. Hayes
    Current Diabetes Reports.2019;[Epub]     CrossRef
  • Endocrine aspects of Klinefelter syndrome
    Adriana Herrera Lizarazo, Michelle McLoughlin, Maria G. Vogiatzi
    Current Opinion in Endocrinology & Diabetes and Obesity.2019; 26(1): 60.     CrossRef
  • Sex differences in metabolism and cardiometabolic disorders
    Karthickeyan Chella Krishnan, Margarete Mehrabian, Aldons J. Lusis
    Current Opinion in Lipidology.2018; 29(5): 404.     CrossRef
  • Klinefelter Syndrome: Integrating Genetics, Neuropsychology, and Endocrinology
    Claus H Gravholt, Simon Chang, Mikkel Wallentin, Jens Fedder, Philip Moore, Anne Skakkebæk
    Endocrine Reviews.2018; 39(4): 389.     CrossRef
  • Sex differences in obesity, lipid metabolism, and inflammation—A role for the sex chromosomes?
    Temeka Zore, Maria Palafox, Karen Reue
    Molecular Metabolism.2018; 15: 35.     CrossRef
  • Klinefelter syndrome, insulin resistance, metabolic syndrome, and diabetes: review of literature and clinical perspectives
    Andrea Salzano, Roberta D’Assante, Liam M. Heaney, Federica Monaco, Giuseppe Rengo, Pietro Valente, Daniela Pasquali, Eduardo Bossone, Daniele Gianfrilli, Andrea Lenzi, Antonio Cittadini, Alberto M. Marra, Raffaele Napoli
    Endocrine.2018; 61(2): 194.     CrossRef
  • Síndrome de Klinefelter y riesgo cardiovascular
    A. Yamaguchi, P. Knoblovits
    Hipertensión y Riesgo Vascular.2018; 35(4): 195.     CrossRef
  • Articles inEndocrinology and Metabolismin 2016
    Won-Young Lee
    Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef
  • Sex differences in obesity: X chromosome dosage as a risk factor for increased food intake, adiposity and co-morbidities
    Karen Reue
    Physiology & Behavior.2017; 176: 174.     CrossRef
  • Klinefelter Syndrome with Morbid Obesity Before Bariatric Surgery: A Case Report
    Parisa Janmohammadi, Gholamreza Mohammadi-Farsani, Hana Arghavani, Mahmoud Arshad, Tayebeh Mokhber
    Journal of Minimally Invasive Surgical Sciences.2017;[Epub]     CrossRef
  • Klinefelter Syndrome and Metabolic Disorder
    Ji Cheol Bae
    Endocrinology and Metabolism.2016; 31(4): 535.     CrossRef
Low Serum Testosterone Concentrations in Hospitalized Men with Poorly Controlled Type 2 Diabetes
Kyung-Soo Kim, San-Ha Kang, Moon-Jong Kim, Soo-Kyung Kim, Yoo-Lee Kim, Won-Keun Park, Seok Won Park, Yong-Wook Cho
Endocrinol Metab. 2014;29(4):574-578.   Published online December 29, 2014
DOI: https://doi.org/10.3803/EnM.2014.29.4.574
  • 2,619 View
  • 26 Download
  • 6 Citations
AbstractAbstract PDFPubReader   CrossRef-TDMCrossref - TDM

Our aim was to examine whether serum testosterone concentrations are in fact low in hospitalized men with poorly controlled type 2 diabetes compared with healthy men. In this study, 79 men aged 40 years or older (41 healthy men and 38 men with type 2 diabetes) were included. Total testosterone and sex hormone-binding globulin levels were measured. The average duration of diagnosed diabetes was 10.8 years and the mean glycated hemoglobin value was 10.8%. Total testosterone concentrations were lower in men with type 2 diabetes than in healthy men, after adjusting for age and body mass index (3.83±0.32 ng/mL vs. 5.63±0.31 ng/mL, P<0.001). In conclusion, this study shows that serum testosterone concentrations are lower in hospitalized men with poorly controlled type 2 diabetes than in healthy men. Therefore, men with poorly controlled type 2 diabetes should undergo further assessment for hypogonadism.

Citations

Citations to this article as recorded by  
  • Nanoparticles of Costus speciosus Ameliorate Diabetes-Induced Structural Changes in Rat Prostate through Mediating the Pro-Inflammatory Cytokines IL 6, IL1β and TNF-α
    Duaa Bakhshwin, Khadija Abdul Jalil Faddladdeen, Soad Shaker Ali, Samar Mohammed Alsaggaf, Nasra Naeim Ayuob
    Molecules.2022; 27(3): 1027.     CrossRef
  • Association between testosterone with type 2 diabetes in adult males, a meta-analysis and trial sequential analysis
    Jianzhong Zhang, Xiao Li, Zhonglin Cai, Hongjun Li, Bin Yang
    The Aging Male.2020; 23(5): 607.     CrossRef
  • Momordica charantia Extract Protects against Diabetes-Related Spermatogenic Dysfunction in Male Rats: Molecular and Biochemical Study
    Gamal A. Soliman, Rehab F. Abdel-Rahman, Hanan A. Ogaly, Hassan N. Althurwi, Reham M. Abd-Elsalam, Faisal F. Albaqami, Maged S. Abdel-Kader
    Molecules.2020; 25(22): 5255.     CrossRef
  • Olive leaves extract attenuates type II diabetes mellitus-induced testicular damage in rats: Molecular and biochemical study
    Gamal A. Soliman, Abdulaziz S. Saeedan, Rehab F. Abdel-Rahman, Hanan A. Ogaly, Reham M. Abd-Elsalam, Maged S. Abdel-Kader
    Saudi Pharmaceutical Journal.2019; 27(3): 326.     CrossRef
  • Effects of testosterone supplement treatment in hypogonadal adult males with T2DM: a meta-analysis and systematic review
    Jianzhong Zhang, Bin Yang, Wenhui Xiao, Xiao Li, Hongjun Li
    World Journal of Urology.2018; 36(8): 1315.     CrossRef
  • RAS and sex differences in diabetic nephropathy
    Sergi Clotet, Marta Riera, Julio Pascual, María José Soler
    American Journal of Physiology-Renal Physiology.2016; 310(10): F945.     CrossRef

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