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Kyu Geun Hwang  (Hwang KG) 1 Article
A Case of Congenital Adrenal Hyperplasia Combined with a Testicular Adrenal Rest Tumor and Adrenal Incidentaloma.
Gyu Rang Cho, Hee Won Chueh, Jung Pyo Kim, Jin A Jung, Jae Ho Yoo, Sung Kook Yoon, Kyu Geun Hwang
J Korean Endocr Soc. 2007;22(5):365-370.   Published online October 1, 2007
DOI: https://doi.org/10.3803/jkes.2007.22.5.365
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AbstractAbstract PDF
The fundamental defect among patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylse deficiency is the inability to synthesize cortisol and aldosterone adequately. Ineffective cortisol synthesis signals the hypothalamus and pituitary to increase the production of corticotropin releasing hormone and adrenocorticotropic hormone, respectively. Consequently, the adrenal glands become hyperplastic. It is well known that an adrenal adenoma can develop from hyperplastic tissue under increased corticotropin stimulation of the adrenal cortex in patients that are suffering with CAH. The etiologic mechanism of adrenal incidentaloma remains uncertain, but several hypotheses have been suggested. A testicular adrenal rest tumor has been reported to form in association with the excessive secretion of adrenal androgen by inadequate control after adolescence in CAH. We present a case of poorly controlled salt-losing CAH due to 21-hydroxylase deficiency combined with a testicular adrenal rest tumor and adrenal incidentaloma.

Citations

Citations to this article as recorded by  
  • A new compound heterozygous mutation in a female with 17α-hydroxylase/17,20-lyase deficiency, slipped capital femoral epiphysis, and adrenal myelolipoma
    Fan Yang, Yongting Zhao, Jie Lv, Xia Sheng, Lihong Wang
    Gynecological Endocrinology.2019; 35(5): 385.     CrossRef
  • A case of testicular adrenal rest tumor in a male child with congenital adrenal hyperplasia
    Joo Hwa Kim, Kyong Ah Yun, Choong Ho Shin, Sei Won Yang
    Korean Journal of Pediatrics.2008; 51(9): 1018.     CrossRef
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