- A Case of Licorice Induced Hypokalemic Paralysis with Rhabdomyolysis.
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Hyun Il Hong, Koon Hee Han, Jung Won Hwang, Young Don Kim, Myung Sook Shim, Jin Yub Kim
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J Korean Endocr Soc. 2005;20(2):179-182. Published online April 1, 2005
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DOI: https://doi.org/10.3803/jkes.2005.20.2.179
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- Prolonged ingestion of licorice can cause hypermineralocorticoidism, with sodium retention, potassium loss and hypertension. Nevertheless, its initial presentation with a very severe degree of hypokalemic paralysis and rhabdomyolysis are exceedingly rare. We describe a patient who experienced hypokalemic paralysis and rhabdomyolysis after licorice ingestion. The patient's initial blood pressure was 160/80mmHg. The major biochemical abnormalities included; hypokalemia(K+ 1.3mEq/L), metabolic alkalosis, with a pH of 7.64, and urine myoglobin > 3000ng/mL. The plasma rennin activity and aldosterone level were suppressed. The 24 hour urine cortisol concentration was normal. The patients, over a 1 month period, had ingested 500g of licorice boiled in water. After quitting the licorice, the hypokalemia and muscle paralysis gradually improved and blood pressure returned to normal
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Citations
Citations to this article as recorded by  - A case of chronic licorice intoxication-induced apparent mineralocorticoid excess syndrome
Young Jae Lim, Ji Eun Kim
Journal of The Korean Society of Clinical Toxicology.2023; 21(2): 151. CrossRef - Hypokalemic Periodic Paralysis Developed in a Patient with Neurogenic Diabetes Insipidus
Jihyeon Hwang, Joo Hye Sung, Ye Eun Kim, Keonyeup Kim, Seong-Hwan Kim, Young Bin Park, Seol-Hee Baek
Journal of the Korean Neurological Association.2021; 39(3): 177. CrossRef - Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
Hyun Kuk Kim, Sung Soo Kim
Translational and Clinical Pharmacology.2019; 27(2): 69. CrossRef - Influence of Herbal Complexes Containing Licorice on Potassium Levels: A Retrospective Study
WooSang Jung, SeungWon Kwon, JinWook Im, SeongUk Park, SangKwan Moon, JungMi Park, ChangNam Ko, KiHo Cho, Paul Posadzki
Evidence-Based Complementary and Alternative Medicine.2014;[Epub] CrossRef
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