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Endocrinol Metab : Endocrinology and Metabolism


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Ji Myung Kim  (Kim JM) 1 Article
A Case of Graves' Disease with Pancytopenia.
Jong Ho Shin, Hyun Jin Kim, Si Bum Kim, Dong Pil Kim, Bong Suk Ko, Dong Soon Kim, Ji Myung Kim, Soo Jung Gong, Jung Ae Lee
J Korean Endocr Soc. 2009;24(4):272-276.   Published online December 1, 2009
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AbstractAbstract PDF
Hematological disorders, and especially single lineage abnormalities, have been described in patients suffering with thyrotoxicosis, but pancytopenia is a rare complication of thyrotoxicosis. Pancytopenia with thyrotoxicosis has been reported to be totally reversible with antithyroid drug treatment. We experienced a case with pancytopenia associated with Graves' disease in a 57-year-old woman who had no specific cause of pancytopenia. She presented with dyspnea and palpitation. The laboratory findings revealed thyrotoxicosis and pancytopenia. Increased radioisotope uptake was seen on the thyroid scan and normal cellularity and maturation were found in the bone marrow aspiration biopsy. Based on these findings, she was diagnosed as suffering from Gravesyendisease with pancytopenia. After treatment with propylthiouracil, the blood cell counts were restored to normal as the patient achieved a euthyroid state. We report here on a case of Graves' disease that was complicated by pancytopenia, and all this was normalized after treatment for hyperthyroidism.


Citations to this article as recorded by  
  • Non-myeloproliferative Pancytopenia: A Rare Presentation of Thyrotoxicosis
    Izzathunnisa Rahmathullah, Maheswaran Umakanth, Suranga Singhapathirane
    Cureus.2023;[Epub]     CrossRef
  • Pancytopenia in a surgical patient, a rare presentation of hyperthyroidism
    Prabhat Jha, Yogendra Prasad Singh, Bikal Ghimire, Binit Kumar Jha
    BMC Surgery.2014;[Epub]     CrossRef
  • A Case of Pancytopenia with Hyperthyroidism
    Tae Hoon Kim, Ji Sung Yoon, Byung Sam Park, Dong Won Lee, Jae Ho Cho, Jun Sung Moon, Eui Hyun Kim, Kyu Chang Won, Hyoung Woo Lee
    Yeungnam University Journal of Medicine.2013; 30(1): 47.     CrossRef
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