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Ji Hyun Kim  (Kim JH) 12 Articles
Clinical Study
Eligibility for Statin Treatment in Korean Subjects with Reduced Renal Function: An Observational Study
Byung Sub Moon, Jongho Kim, Ji Hyun Kim, Young Youl Hyun, Se Eun Park, Hyung-Geun Oh, Cheol-Young Park, Won-Young Lee, Ki-Won Oh, Kyu-Beck Lee, Hyang Kim, Sung-Woo Park, Eun-Jung Rhee
Endocrinol Metab. 2016;31(3):402-409.   Published online August 26, 2016
DOI: https://doi.org/10.3803/EnM.2016.31.3.402
  • 4,501 View
  • 33 Download
  • 4 Web of Science
  • 4 Crossref
AbstractAbstract PDFPubReader   
Background

The purpose of this study was to investigate the relationship between statin eligibility and the degree of renal dysfunction using the Adult Treatment Panel (ATP) III and the American College of Cardiology (ACC)/American Heart Association (AHA) guidelines in Korean adults.

Methods

Renal function was assessed in 18,746 participants of the Kangbuk Samsung Health Study from January 2011 to December 2012. Subjects were divided into three groups according to estimated glomerular filtration rate (eGFR): stage 1, eGFR ≥90 mL/min/1.73 m2; stage 2, eGFR 60 to 89 mL/min/1.73 m2; and stages 3 to 5, eGFR <60 mL/min/1.73 m2. Statin eligibility in these groups was determined using the ATP III and ACC/AHA guidelines, and the risk for 10-year atherosclerotic cardiovascular disease (ASCVD) was calculated using the Framingham Risk Score (FRS) and Pooled Cohort Equation (PCE).

Results

There were 3,546 (18.9%) and 4,048 (21.5%) statin-eligible subjects according to ATP III and ACC/AHA guidelines, respectively. The proportion of statin-eligible subjects increased as renal function deteriorated. Statin eligibility by the ACC/AHA guidelines showed better agreement with the Kidney Disease Improving Global Outcomes (KDIGO) recommendations compared to the ATP III guidelines in subjects with stage 3 to 5 chronic kidney disease (CKD) (κ value, 0.689 vs. 0.531). When the 10-year ASCVD risk was assessed using the FRS and PCE, the mean risk calculated by both equations significantly increased as renal function declined.

Conclusions

The proportion of statin-eligible subjects significantly increased according to worsening renal function in this Korean cohort. ACC/AHA guideline showed better agreement for statin eligibility with that recommended by KDIGO guideline compared to ATP III in subjects with CKD.

Citations

Citations to this article as recorded by  
  • Association between atherosclerotic cardiovascular diseases risk and renal outcome in patients with type 2 diabetes mellitus
    Honghong Ren, Lijun Zhao, Yutong Zou, Yiting Wang, Junlin Zhang, Yucheng Wu, Rui Zhang, Tingli Wang, Jiali Wang, Yitao Zhu, Ruikun Guo, Huan Xu, Lin Li, Mark E. Cooper, Fang Liu
    Renal Failure.2021; 43(1): 477.     CrossRef
  • Long-term effects of various types of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on changes in glomerular filtration rate in Korea
    Seo Yeon Baik, Hyunah Kim, So Jung Yang, Tong Min Kim, Seung-Hwan Lee, Jae Hyoung Cho, Hyunyong Lee, Hyeon Woo Yim, Kun-Ho Yoon, Hun-Sung Kim
    Frontiers of Medicine.2019; 13(6): 713.     CrossRef
  • Analysis and comparison of the cost-effectiveness of statins according to the baseline low-density lipoprotein cholesterol level in Korea
    Y. J. Jeong, H. Kim, S. J. Baik, T. M. Kim, S. J. Yang, S.-H. Lee, J.-H. Cho, H. Lee, H. W. Yim, I. Y. Choi, K.-H. Yoon, H.-S. Kim
    Journal of Clinical Pharmacy and Therapeutics.2017; 42(3): 292.     CrossRef
  • Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes
    Eugene Han, Gyuri Kim, Ji-Yeon Lee, Yong-ho Lee, Beom Seok Kim, Byung-Wan Lee, Bong-Soo Cha, Eun Seok Kang
    Endocrinology and Metabolism.2017; 32(2): 274.     CrossRef
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Obesity and Metabolism
Understanding Metabolomics in Biomedical Research
Su Jung Kim, Su Hee Kim, Ji Hyun Kim, Shin Hwang, Hyun Ju Yoo
Endocrinol Metab. 2016;31(1):7-16.   Published online March 16, 2016
DOI: https://doi.org/10.3803/EnM.2016.31.1.7
  • 8,219 View
  • 144 Download
  • 51 Web of Science
  • 49 Crossref
AbstractAbstract PDFPubReader   

The term "omics" refers to any type of specific study that provides collective information on a biological system. Representative omics includes genomics, proteomics, and metabolomics, and new omics is constantly being added, such as lipidomics or glycomics. Each omics technique is crucial to the understanding of various biological systems and complements the information provided by the other approaches. The main strengths of metabolomics are that metabolites are closely related to the phenotypes of living organisms and provide information on biochemical activities by reflecting the substrates and products of cellular metabolism. The transcriptome does not always correlate with the proteome, and the translated proteome might not be functionally active. Therefore, their changes do not always result in phenotypic alterations. Unlike the genome or proteome, the metabolome is often called the molecular phenotype of living organisms and is easily translated into biological conditions and disease states. Here, we review the general strategies of mass spectrometry-based metabolomics. Targeted metabolome or lipidome analysis is discussed, as well as nontargeted approaches, with a brief explanation of the advantages and disadvantages of each platform. Biomedical applications that use mass spectrometry-based metabolomics are briefly introduced.

Citations

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    Journal of Separation Science.2024;[Epub]     CrossRef
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    Mass Spectrometry Reviews.2024;[Epub]     CrossRef
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    Yangchang Zhang, Shi Zhao, Wangnan Cao, Shengzhi Sun, Qiang Zeng, Peng Luo
    Environment & Health.2024;[Epub]     CrossRef
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    Environmental Research.2023; 216: 114570.     CrossRef
  • UPLC-Q-Exactive-based rats serum metabolomics for characterization of traditional Chinese medicine Natures and Flavors
    Hong Wang, Ruofang Gao, Jing Liu, Shuang Zhang, Yunli Zhao, Zhiguo Yu
    Journal of Ethnopharmacology.2023; 302: 115931.     CrossRef
  • Artificial Neural Networks Coupled with MALDI-TOF MS Serum Fingerprinting To Classify and Diagnose Pathological Pain Subtypes in Preclinical Models
    Meritxell Deulofeu, Eladia M. Peña-Méndez, Petr Vaňhara, Josef Havel, Lukáš Moráň, Lukáš Pečinka, Anna Bagó-Mas, Enrique Verdú, Victoria Salvadó, Pere Boadas-Vaello
    ACS Chemical Neuroscience.2023; 14(2): 300.     CrossRef
  • Metabolic signature of HepaRG cells exposed to ethanol and tumor necrosis factor alpha to study alcoholic steatohepatitis by LC–MS-based untargeted metabolomics
    Elias Iturrospe, Rani Robeyns, Katyeny Manuela da Silva, Maria van de Lavoir, Joost Boeckmans, Tamara Vanhaecke, Alexander L. N. van Nuijs, Adrian Covaci
    Archives of Toxicology.2023; 97(5): 1335.     CrossRef
  • Integrating metabolomics and network pharmacology to assess the effects of quercetin on lung inflammatory injury induced by human respiratory syncytial virus
    Ya-Lei Sun, Pei-Pei Zhao, Cheng-Bi Zhu, Ming-Chen Jiang, Xin-Min Li, Jia-Lei Tao, Chan-Chan Hu, Bin Yuan
    Scientific Reports.2023;[Epub]     CrossRef
  • Comparison of Plasma Metabolites From Patients With Non-Small Cell Lung Cancer by Erlotinib Treatment and Skin Rash
    Won Kil Lee, Jisoo Myong, Eunbin Kwag, Younmin Shin, Ji Woong Son, Byong Chul Yoo, Byoung-Soo Kim, Hwa-Seung Yoo, Jeong June Choi
    Integrative Cancer Therapies.2023;[Epub]     CrossRef
  • Metabolomic Signatures of Exposure to Nitrate and Trihalomethanes in Drinking Water and Colorectal Cancer Risk in a Spanish Multicentric Study (MCC-Spain)
    Jose A. Alcolea, Carolina Donat-Vargas, Anastasia Chrysovalantou Chatziioannou, Pekka Keski-Rahkonen, Nivonirina Robinot, Antonio José Molina, Pilar Amiano, Inés Gómez-Acebo, Gemma Castaño-Vinyals, Lea Maitre, Marc Chadeau-Hyam, Sonia Dagnino, Sibo Lucas
    Environmental Science & Technology.2023; 57(48): 19316.     CrossRef
  • Metabolic Signature of Ethanol-Induced Hepatotoxicity in HepaRG Cells by Liquid Chromatography–Mass Spectrometry-Based Untargeted Metabolomics
    Elias Iturrospe, Katyeny Manuela da Silva, Rani Robeyns, Maria van de Lavoir, Joost Boeckmans, Tamara Vanhaecke, Alexander L.N. van Nuijs, Adrian Covaci
    Journal of Proteome Research.2022; 21(4): 1153.     CrossRef
  • Current State and Challenges of the Global Outcomes of Dental Caries Research in the Meta-Omics Era
    Dina G. Moussa, Paras Ahmad, Tamer A. Mansour, Walter L. Siqueira
    Frontiers in Cellular and Infection Microbiology.2022;[Epub]     CrossRef
  • Current Knowledge in Skin Metabolomics: Updates from Literature Review
    Alessia Paganelli, Valeria Righi, Elisabetta Tarentini, Cristina Magnoni
    International Journal of Molecular Sciences.2022; 23(15): 8776.     CrossRef
  • Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers
    Donghai Liang, Jonathan Batross, Nancy Fiedler, Tippawan Prapamontol, Panrapee Suttiwan, Parinya Panuwet, Warangkana Naksen, Brittney O. Baumert, Volha Yakimavets, Youran Tan, Priya D'Souza, Ampica Mangklabruks, Supattra Sittiwang, Kristsanachai Kaewthit,
    Environmental Research.2022; 215: 114319.     CrossRef
  • Differential Plasma Metabolites between High- and Low-Grade Meningioma Cases
    Gabriel A. Kurokawa, Pedro T. Hamamoto Filho, Jeany Delafiori, Aline F. Galvani, Arthur N. de Oliveira, Flávia L. Dias-Audibert, Rodrigo R. Catharino, Maria Inês M. C. Pardini, Marco A. Zanini, Estela de O. Lima, Adriana C. Ferrasi
    International Journal of Molecular Sciences.2022; 24(1): 394.     CrossRef
  • Plasma metabolites associated with exposure to perfluoroalkyl substances and risk of type 2 diabetes – A nested case-control study
    Tessa Schillemans, Lin Shi, Carolina Donat-Vargas, Kati Hanhineva, Andreas Tornevi, Ingegerd Johansson, Jani Koponen, Hannu Kiviranta, Olov Rolandsson, Ingvar A. Bergdahl, Rikard Landberg, Agneta Åkesson, Carl Brunius
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  • Methionine transsulfuration pathway is upregulated in long-lived humans
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    Metabolites.2021; 11(2): 118.     CrossRef
  • Broad Metabolome Alterations Associated with the Intake of Oral Contraceptives Are Mediated by Cortisol in Premenopausal Women
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    Won-Young Lee
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Close layer
A Case of Painless Thyroiditis Followed by Graves' Disease.
Gyeong Jae Na, Ji Hyun Kim, Se Yoon Park, Ki Won Kim, Hee Ja Ko, Sung Wan Jeon, Yeo Joo Kim, Sang Jin Kim
Endocrinol Metab. 2012;27(2):147-150.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.147
  • 2,434 View
  • 38 Download
  • 1 Crossref
AbstractAbstract PDF
A 30-year-old man was admitted to our hospital because of fatigue, palpitation and severe weakness of both legs. The admission laboratory findings revealed thyrotoxicosis, and 131I thyroid scintigraphic imaging revealed a low radioactive iodine uptake. He was treated for painless thyroiditis for about 4 months. However, thyrotoxic state had continued and radioactive iodine uptake was markedly increased in the follow up scan. Painless thyroiditis often relapses, but rarely develops into Graves' disease. This is a rare case in which painless thyroiditis was followed by Graves' disease.

Citations

Citations to this article as recorded by  
  • A Case of Severe Recurrent Painless Thyroiditis Requiring Thyroidectomy
    So Hyun Park, Il Seong Nam-Goong, Young Il Kim, Yun Sun Kim, Yung Min Kim, Eun Sook Kim
    Journal of Korean Thyroid Association.2015; 8(1): 113.     CrossRef
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Papillary Thyroid Carcinoma Manifesting as an Autonomously Functioning Thyroid Nodule.
Ji Hyun Kim, Gyeong Jae Na, Ki Won Kim, Hee Ja Ko, Sung Wan Jeon, Yeo Joo Kim, Sang Jin Kim, Hyeun Duk Jo, Chang Jin Kim
Endocrinol Metab. 2012;27(1):59-62.   Published online March 1, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.1.59
  • 66,499 View
  • 32 Download
  • 3 Crossref
AbstractAbstract PDF
Hyperfunctioning thyroid carcinoma is very rare. Hence, radionuclide imaging of thyroid hot nodules usually suggests a benign tumor, and less than 4% of cases have been reported as malignant. We would like to present a case of a hyperfunctioning papillary thyroid carcinoma that was initially treated with radioactive iodine. A 58-year-old woman was referred to our hospital for palpable thyroid nodule and a 5-kg weight loss within 6 months. Thyroid function test revealed thyrotoxicosis, and thyroid autoantibodies were absent. 99mTc thyroid scintigraphy showed a 2 x 2 cm-sized hyperactive hot nodule at the left lobe. Despite radioactive iodine treatment with a dose of 10 mCi 131I, thyroid function did not improve. Fine needle aspiration revealed papillary thyroid cancer. The patient underwent total thyroidectomy. Although clinical features and thyroid scans suggest a benign nodule, the possibility of malignancy should not be ruled out. Malignant thyroid hot nodules are rare; however, its possibility should be taken into account. Therefore, we suggest that ruling out malignancy by existing diagnostic guidelines can misdiagnose even a typical case with benign features. As thyroid nodule detection is getting sensitive and accurate, we present this case to discuss whether additional diagnostic approaches would be necessary for thyroid nodules.

Citations

Citations to this article as recorded by  
  • Ultrasonographic Characteristics of the Hyperfunctioning Thyroid Nodule and Predictive Factors for Thyroid Stimulating Hormone Suppression
    Won Sang Yoo, Hoon Sung Choi
    International Journal of Thyroidology.2019; 12(1): 35.     CrossRef
  • Papillary Thyroid Carcinoma Presented as a Hot Nodule with Hyperthyroidism
    Sung Hye Kong, Seo Young Lee, Ye Seul Yang, Jae Hoon Moon
    International Journal of Thyroidology.2016; 9(1): 47.     CrossRef
  • Follicular variant of papillary thyroid carcinoma: an unusual cause of thyrotoxicosis
    David Owen Rees, Victoria Angharad Anthony, Keston Jones, Jeffrey W Stephens
    BMJ Case Reports.2015; : bcr2014207091.     CrossRef
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A Case of Ectopic Neurohypophysis Presenting with Hypogonadism.
In Woon Baek, Ji Hyun Kim, Guk Jin Lee, Kyoung Eun Lee, Hae Lim Lee, Hye Won Lee, Nam Yong Kim, Yon Kwon Ihn, Seung Hyun Ko, Seung Hwan Lee, Je Ho Han
Endocrinol Metab. 2011;26(1):67-71.   Published online March 1, 2011
DOI: https://doi.org/10.3803/EnM.2011.26.1.67
  • 2,449 View
  • 27 Download
  • 2 Crossref
AbstractAbstract PDF
Pituitary stalk interruption and ectopic neurohypophysis seen on magnetic resonance Imaging (MRI) are often associated with either isolated growth hormone (GH) deficiency or combined anterior pituitary hormone deficiency, but their pathogenesis is not clear and the clinical data regarding these anatomical defect is limited. We experienced a 23-year-old male with the absence of secondary sexual characteristics and this was accompanied with pituitary stalk dysgenesis and ectopic neurohypophysis. He received growth hormone for a year when he was 12 years old due to his short stature. Sella MRI showed no visible pituitary stalk with minimal high signal change, suggesting ectopic neurohypophysis. The combined pituitary stimulation test revealed blunted responses of growth hormone, follicle stimulating hormone and luteinizing hormone. For the hypogonadotropic hypogonadism, the patient was given testosterone intramuscularly and he gradually developed secondary sexual characteristics. We concluded that the hypogonadism and growth hormone deficiency in this patient was caused by hypopituitarism due to pituitary stalk dysgenesis and ecopic nuerohypophysis.

Citations

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  • MRI of ectopic posterior pituitary gland with dysgenesis of pituitary stalk in a patient with hypogonadotropic hypogonadism
    Ashim Kumar Lahiri, Ramanivas Sundareyan, David Jenkins, Anjumara Nilak
    Radiology Case Reports.2018; 13(4): 764.     CrossRef
  • Hypothalamic Hypopituitarism Caused by Pituitary Stalk Dysgenesis
    Seong-Ju Lee, Hye-Jin Yoon, A-Reum Cho, Yoo-Jin Um, Keun-Young Park, Dong-Mee Lim, Byung-Joon Kim
    Korean Journal of Medicine.2013; 85(4): 420.     CrossRef
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A Case of Sporadic Medullary Thyroid Cancer with RET G691S Polymorphism.
Min Kyu Kang, Jung Min Lee, Ji Hyun Kim, Min Young Lee, Ji Hyun Kim, Sung Dae Moon, Je Ho Han, Sang Ah Chang
J Korean Endocr Soc. 2009;24(4):293-297.   Published online December 1, 2009
DOI: https://doi.org/10.3803/jkes.2009.24.4.293
  • 2,030 View
  • 25 Download
AbstractAbstract PDF
Sporadic medullary thyroid carcinoma (MTC) is the most common form of MTC and somatic RET proto-oncogene mutations account for approximately 25% of the patients with sporadic MTC. However, other pathogeneses of sporadic MTC are still unclear. Not only RET mutation, but also polymorphisms of RET may have an association with sporadic MTC. We herein describe the association of MTC and RET proto-oncogene polymorphism. A 51-year-old man was diagnosed with MTC, which was incidentally found on a thyroid sonogram. The patient underwent total thyroidectomy and genetic mutational analysis of the RET gene. Genetic testing detected a polymorphism in codon 691 (G691S) on exon 11 of the RET proto-oncogene. His son and daughter had the same polymorphism. We report on this case along with a review of the related literature on RET gene polymorphism of sporadic MTC.
Close layer
A Case of Sporadic Medullary Thyroid Cancer with RET G691S Polymorphism.
Min Kyu Kang, Jung Min Lee, Ji Hyun Kim, Min Young Lee, Ji Hyun Kim, Sung Dae Moon, Je Ho Han, Sang Ah Chang
J Korean Endocr Soc. 2009;24(4):293-297.   Published online December 1, 2009
DOI: https://doi.org/10.3803/jkes.2009.24.4.293
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AbstractAbstract PDF
Sporadic medullary thyroid carcinoma (MTC) is the most common form of MTC and somatic RET proto-oncogene mutations account for approximately 25% of the patients with sporadic MTC. However, other pathogeneses of sporadic MTC are still unclear. Not only RET mutation, but also polymorphisms of RET may have an association with sporadic MTC. We herein describe the association of MTC and RET proto-oncogene polymorphism. A 51-year-old man was diagnosed with MTC, which was incidentally found on a thyroid sonogram. The patient underwent total thyroidectomy and genetic mutational analysis of the RET gene. Genetic testing detected a polymorphism in codon 691 (G691S) on exon 11 of the RET proto-oncogene. His son and daughter had the same polymorphism. We report on this case along with a review of the related literature on RET gene polymorphism of sporadic MTC.
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Primary Hypogonadism Associated with Ankylosing Spondylitis.
Byoung Yeon Jun, Guk Jin Lee, Ji Hyun Kim, Jung Min Lee, Sang Ah Chang
J Korean Endocr Soc. 2008;23(5):352-357.   Published online October 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.5.352
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  • 2 Crossref
AbstractAbstract PDF
Male patients with hypogonadism have an increased risk of developing rheumatic diseases. Most causes of hypogonadism related with rheumatic disease are karyotype abnormality such as Klinefelter's syndrome or Turner's syndrome and gonadal dysgenesis. A 24-year-old year male was admitted for pain of both hip joints that had worsened over 2 months. He had hip joint involvement from ankylosing spondylitis and did not show secondary sex characteristics. His sex hormones and gonadotropins levels indicated hypergonadotropic hypogonadism. The karyotype was 46 XY, and there was no obvious cause of hypogonadism. Here we report on clinical features of this first Korean case of primary hypogonadism accompanying ankylosing spondylitis.

Citations

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  • Ankylosing spondylitis associated with balanced reciprocal X-1 translocation
    Young Hoon Kim, Jung Ouk Lee
    Yeungnam University Journal of Medicine.2017; 34(1): 80.     CrossRef
  • A Case of Klinefelter's Syndrome Accompanying with Polymyositis
    Min Kyu Lee, Byung Sik Kim, Suk Hyun Jung, Gun Hwa Lee, Jin Ok Kim, Dong Hwi Rim, Yu Hwa Lee, Woong Jun Kim, So-Young Bang, Hye-Soon Lee
    Journal of Rheumatic Diseases.2012; 19(3): 152.     CrossRef
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A Case of Pneumocystis Carinii Pneumonia and Cutaneous Nocardiosis Associated with Ectopic ACTH Syndrome.
Hee Sun Jung, Seung Hwan Lee, Hee Yeon Kim, Eun Ho Chu, Kang Woo Lee, Mi Ja Kang, Ji Hyun Kim, Hyuk Sang Kwon, Kun Ho Yoon, Bong Yun Cha, Ho Young Son
J Korean Endocr Soc. 2008;23(1):44-50.   Published online February 1, 2008
DOI: https://doi.org/10.3803/jkes.2008.23.1.44
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AbstractAbstract PDF
Cushing's syndrome is characterized by hypercortisolism and impairment of cell-mediated immune function, increasing the risk of opportunistic infection, as occurs in other immunocompromised groups such as organ transplant recipients, patients with lymphoreticular malignancy, or acquired immunodeficiency syndrome. We report a case of a 68-year-old woman who was affected with pneumocystis carinii pneumonia (PCP) 8 years ago and cutaneous nocardiosis this year. The patient was diagnosed with ectopic ACTH syndrome 8 years ago, but no ectopic ACTH secreting focus was found in radiologic imaging studies. She recovered from PCP and cutaneous nocardiosis after antibiotic (trimethoprim-sulfamethoxazole) administration. After the infection resolved, she underwent laparoscopic bilateral adrenalectomy and was not longer hypercortisolemic.
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Diabetic Ketoacidosis in a Patient with Long-term Clozapine Therapy.
Youn Joo Jeon, Seung Hwan Lee, Se Na Jang, Eun Sun Kim, Jeong Yo Min, Ji Hyun Kim, Soon Hwa Hong, Jae Hyoung Cho, Hyuk Sang Kwon, Kun Ho Yoon, Bong Yun Cha, Ho Young Son
J Korean Endocr Soc. 2007;22(5):376-380.   Published online October 1, 2007
DOI: https://doi.org/10.3803/jkes.2007.22.5.376
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AbstractAbstract PDF
With the broad use of atypical anti-psychotics, altered glucose metabolism has become an item of concern to clinicians and patients. Among the atypical anti-psychotics, clozapine and olanzapine are associated with a relatively high incidence of diabetic ketoacidosis and newly developed diabetes. We report a case of diabetic ketoacidosis in a patient with long-term clozapine therapy. A 35-year-old male with schizophrenia, treated with clozapine for 9 years was admitted into hospital because of comatous mentality. Although never diagnosed with diabetes before, his clinical features were consistent with diabetic ketoacidosis and shock. The patient's serum amylase and lipase levels were elevated and an abdominal computed tomography showed peripancreatic fat infiltration, suggesting the possibility of acute pancreatitis. The patient's serum glucose levels normalized shortly after clozapine treatment. Moreover, the patient ceased all glucose lowering agents upon hospital discharge, and maintained normal blood glucose levels thereafter. As observed in this case, clinicians should carefully screen and monitor blood glucose levels and other clinical parameters in patients treated with atypical anti-psychotics.

Citations

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  • Two Cases of Diabetic Ketoacidosis Associated with Paliperidone Treatment in Schizophrenia
    Hyun Ho Kim, Hae Kyung Yang, Hyoju Ham, Ho Wook Jeon, Joon Yub Lee, Sea Won Hwang, Bo Hyun Jang, Gi June Min, Jeong Min Lee, Seung-Hwan Lee
    The Journal of Korean Diabetes.2014; 15(3): 178.     CrossRef
  • Olanzapine-Induced Diabetic Ketoacidosis and Neuroleptic Malignant Syndrome with Rhabdomyolysis: A Case Report
    Young Kyoung Sa, Hyeon Yang, Hee Kyoung Jung, Jang Won Son, Seong Su Lee, Seong Rae Kim, Bong Yeon Cha, Ho Young Son, Chi-Un Pae, Soon Jib Yoo
    Endocrinology and Metabolism.2013; 28(1): 70.     CrossRef
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A Patient with Concurrent Medullary and Papillary Carcinoma of the Thyroid.
Seung Hee Yoo, Keun Joon Lim, Seung Hwan Lee, Ji Hyun Kim, Soon Hwa Hong, Jae Hyoung Cho, Chan Kwon Jung, Hyuk Sang Kwon, Kun Ho Yoon, Min Sik Kim, Bong Yun Cha, Ho Young Son
J Korean Endocr Soc. 2007;22(3):235-240.   Published online June 1, 2007
DOI: https://doi.org/10.3803/jkes.2007.22.3.235
  • 2,047 View
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  • 1 Crossref
AbstractAbstract PDF
The origin of medullary thyroid carcinoma and papillary thyroid carcinoma are embryogenically different, so these tumors have been thought to be independent of each other. We experienced a case of concurrent medullary and papillary thyroid carcinoma in one patient. The patient underwent total thyroidectomy and both two tumors were located at different lobes, respectively. Both tumors showed their own characteristic pathologic and immunohistochemical findings. The patient's elevated calcitonin level returned to the normal range after operation and there has been no evidence of recurrence. It is still controversial whether the concurrency is just coincidental or it arises from activation of a common tumorigenic pathway.

Citations

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  • A Case of Concurrent Papillary and Medullary Thyroid Carcinomas Detected as Recurrent Medullary Carcinoma after Initial Surgery for Papillary Carcinoma
    Dongbin Ahn, Jin Ho Sohn, Ji Young Park
    Journal of Korean Thyroid Association.2013; 6(1): 80.     CrossRef
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A Case of Pituitary Metastasis of Breast Cancer Presenting as Diabetes Insipidus and Panhypopituitarism.
Jae Wuk Kwak, Byung Soo Jie, Sun Hwa Hong, Ji Hyun Kim, Seung Hwan Lee, Jae Hyung Jo, Hyuk Sang Kwon, Kun Ho Youn, Bong Yun Cha, Ho Young Son
J Korean Endocr Soc. 2007;22(2):125-129.   Published online April 1, 2007
DOI: https://doi.org/10.3803/jkes.2007.22.2.125
  • 2,594 View
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  • 2 Crossref
AbstractAbstract PDF
Metastasis to the pituitary gland from systemic cancer is a rare condition. The breast and lung are the most common sites of primary tumor metastasis. Pituitary metastasis may present with diabetes insipidus, cranial nerve palsy and hypopituitarism, and diabetes insipidus is the most frequent symptom at presentation. We report here on a 44 year-old woman with pituitary metastasis from breast cancer, and she developed central diabetes insipidus and hypopituitarism. The clinical diagnosis was made by performing a water deprivation test, a combined pituitary test and a MRI brain scan, and the latter showed metastatic tumor in the pituitary gland with invasion of the pituitary stalk. Symptomatic relief was obtained with administration of desmopressin; the urine osmolarity was increased with this treatment. We report here on a case of pituitary metastasis from breast cancer and the patient developed central diabetes insipidus and hypopituitarism. We also include a review of the relevant literature.

Citations

Citations to this article as recorded by  
  • A Case of Pituitary Metastasis from Breast Cancer That Presented as Left Visual Disturbance
    Young Ha Kim, Beom jun Lee, Kyung Jin Lee, Jin Hee Cho
    Journal of Korean Neurosurgical Society.2012; 51(2): 94.     CrossRef
  • A Case of Panhypopituitarism and Central Diabetes Insipidus Caused by Primary Central Nervous System Lymphoma
    Mi Sun Ahn, Soon Sun Kim, Tae Ho Kim, Seung Jin Han, Dae Jung Kim, Hugh Chul Kim, Se Hyuk Kim, Jae Ho Han, Ho Sung Kim, Yoon-Sok Chung
    Journal of Korean Endocrine Society.2008; 23(4): 260.     CrossRef
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