- Bone Metabolism
- Long-Term Treatment of Postmenopausal Osteoporosis
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Jacques P. Brown
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Endocrinol Metab. 2021;36(3):544-552. Published online June 22, 2021
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DOI: https://doi.org/10.3803/EnM.2021.301
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Abstract
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- Osteoporosis is an incurable chronic condition, like heart disease, diabetes, or hypertension. A large gap currently exists in the primary prevention of fractures, and studies show that an estimated 80% to 90% of adults do not receive appropriate osteoporosis management even in the secondary prevention setting. Case finding strategies have been developed and effective pharmacological interventions are available. This publication addresses how best to use the pharmacological options available for postmenopausal osteoporosis to provide lifelong fracture protection in patients at high and very high risk of fracture. The benefit of osteoporosis therapies far outweighs the rare risks.
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Citations
Citations to this article as recorded by 
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Xiaoyu Cai, Zhi Li, Yao Yao, Yongquan Zheng, Meng Zhang, Yiqing Ye Biochemical Pharmacology.2024; 219: 115951. CrossRef - CircRNA hsa_circ_0006859 inhibits the osteogenic differentiation of BMSCs and aggravates osteoporosis by targeting miR-642b-5p/miR-483-3p and upregulating EFNA2/DOCK3
Peng Yin, Yuan Xue International Immunopharmacology.2023; 116: 109844. CrossRef - Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy
Weiye Cai, Bin Sun, Chao Song, Fei Liu, Zhengliang Wu, Zongchao Liu BMC Complementary Medicine and Therapies.2023;[Epub] CrossRef - Oridonin Attenuates Thioacetamide-Induced Osteoclastogenesis Through MAPK/NF-κB Pathway and Thioacetamide-Inhibited Osteoblastogenesis Through BMP-2/RUNX2 Pathway
XiaoLi Jin, Jia Xu, Fanfan Yang, Jin Chen, Feng Luo, Bin Xu, Jian Xu Calcified Tissue International.2023; 112(6): 704. CrossRef - Phytochemical Compounds Involved in the Bone Regeneration Process and Their Innovative Administration: A Systematic Review
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Jun Jiang, Jinjin He, Shichang Xiao, Jiayi Shenyuan, Tong Chen, Dan Pei Biomedical Chromatography.2023;[Epub] CrossRef - Study on the Effect of Bushen Zhuanggu Tablet Combined with Conventional Regimen on Bone Mineral Density Improvement, Functional Recovery and Fracture Risk Prevention in Patients with Postmenopausal Osteoporosis
Tianliang Chen, Guilan Li, Yongtao Xu, Min Tang Computational and Mathematical Methods in Medicine.2023; 2023: 1. CrossRef - Circ_0001825 promotes osteogenic differentiation in human-derived mesenchymal stem cells via miR-1270/SMAD5 axis
Changjun Zheng, Lingzhi Ding, Ziming Xiang, Mingxuan Feng, Fujiang Zhao, Zhaoxin Zhou, Chang She Journal of Orthopaedic Surgery and Research.2023;[Epub] CrossRef - Identification of ROCK1 as a novel biomarker for postmenopausal osteoporosis and pan-cancer analysis
Bowen Lai, Heng Jiang, Yuan Gao, Xuhui Zhou Aging.2023; 15(17): 8873. CrossRef - The Mechanotransduction Signaling Pathways in the Regulation of Osteogenesis
Zhaoshuo Liu, Qilin Wang, Junyou Zhang, Sihan Qi, Yingying Duan, Chunyan Li International Journal of Molecular Sciences.2023; 24(18): 14326. CrossRef - Decoding the mechanism of Eleutheroside E in treating osteoporosis via network pharmacological analysis and molecular docking of osteoclast-related genes and gut microbiota
Tianyu Zhou, Yilin Zhou, Dongdong Ge, Youhong Xie, Jiangyan Wang, Lin Tang, Qunwei Dong, Ping Sun Frontiers in Endocrinology.2023;[Epub] CrossRef - Epigallocatechin gallate alleviates osteoporosis by regulating the gut microbiota and serum metabolites in rats
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Wei Fan, Zong-Zhe Jiang, Sheng-Rong Wan Medicine.2023; 102(46): e35887. CrossRef - Network pharmacology-based pharmacological mechanism prediction of Lycii Fructus against postmenopausal osteoporosis
Jianbo Wang, Yi Wang, Leyan Li, Shuiqi Cai, Dandan Mao, Hongkan Lou, Jian Zhao Medicine.2023; 102(48): e36292. CrossRef - Benefits of lumican on human bone health: clinical evidence using bone marrow aspirates
Yun Sun Lee, So Jeong Park, Jin Young Lee, Eunah Choi, Beom-Jun Kim The Korean Journal of Internal Medicine.2022; 37(4): 821. CrossRef - ED-71 inhibited osteoclastogenesis by enhancing EphrinB2–EphB4 signaling between osteoclasts and osteoblasts in osteoporosis
Yuan Zhang, Yuying Kou, Panpan Yang, Xing Rong, Rong Tang, Hongrui Liu, Minqi Li Cellular Signalling.2022; 96: 110376. CrossRef - Effects of Muscles on Bone Metabolism—with a Focus on Myokines
Beom-Jun Kim Annals of Geriatric Medicine and Research.2022; 26(2): 63. CrossRef - Evaluation of the tolerability of zoledronic acid preparations for parenteral administration
I. A. Shafieva, S. V. Bulgakova, A. V. Shafieva Meditsinskiy sovet = Medical Council.2022; (11): 96. CrossRef - Impact of Alendronate Sodium plus Elcatonin on Postoperative Bone Pain in Patients with Osteoporotic Fractures
Baohui Wang, Yindi Sun, Da Shi, Xiuwei Han, Na Liu, Bo Wang, Zhijun Liao BioMed Research International.2022; 2022: 1. CrossRef - Current use of bone turnover markers in the management of osteoporosis
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