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Hyun Il Hong  (Hong HI) 1 Article
A Case of Licorice Induced Hypokalemic Paralysis with Rhabdomyolysis.
Hyun Il Hong, Koon Hee Han, Jung Won Hwang, Young Don Kim, Myung Sook Shim, Jin Yub Kim
J Korean Endocr Soc. 2005;20(2):179-182.   Published online April 1, 2005
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  • 4 Crossref
AbstractAbstract PDF
Prolonged ingestion of licorice can cause hypermineralocorticoidism, with sodium retention, potassium loss and hypertension. Nevertheless, its initial presentation with a very severe degree of hypokalemic paralysis and rhabdomyolysis are exceedingly rare. We describe a patient who experienced hypokalemic paralysis and rhabdomyolysis after licorice ingestion. The patient's initial blood pressure was 160/80mmHg. The major biochemical abnormalities included; hypokalemia(K+ 1.3mEq/L), metabolic alkalosis, with a pH of 7.64, and urine myoglobin > 3000ng/mL. The plasma rennin activity and aldosterone level were suppressed. The 24 hour urine cortisol concentration was normal. The patients, over a 1 month period, had ingested 500g of licorice boiled in water. After quitting the licorice, the hypokalemia and muscle paralysis gradually improved and blood pressure returned to normal


Citations to this article as recorded by  
  • A case of chronic licorice intoxication-induced apparent mineralocorticoid excess syndrome
    Young Jae Lim, Ji Eun Kim
    Journal of The Korean Society of Clinical Toxicology.2023; 21(2): 151.     CrossRef
  • Hypokalemic Periodic Paralysis Developed in a Patient with Neurogenic Diabetes Insipidus
    Jihyeon Hwang, Joo Hye Sung, Ye Eun Kim, Keonyeup Kim, Seong-Hwan Kim, Young Bin Park, Seol-Hee Baek
    Journal of the Korean Neurological Association.2021; 39(3): 177.     CrossRef
  • Electrical storm induced by hypokalemia associated with herbal medicines containing licorice
    Hyun Kuk Kim, Sung Soo Kim
    Translational and Clinical Pharmacology.2019; 27(2): 69.     CrossRef
  • Influence of Herbal Complexes Containing Licorice on Potassium Levels: A Retrospective Study
    WooSang Jung, SeungWon Kwon, JinWook Im, SeongUk Park, SangKwan Moon, JungMi Park, ChangNam Ko, KiHo Cho
    Evidence-Based Complementary and Alternative Medicine.2014; 2014: 1.     CrossRef
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