A solitary skin metastasis is a rare manifestation of papillary thyroid carcinoma (PTC). A 55-year-old woman presented with a movable subcutaneous nodule in her anterior neck for several months. Three years ago, she underwent total thyroidectomy and remnant ablation for classical PTC (pT3N0M0) and was under thyroxine suppression therapy without any evidence of recurrent disease. The subcutaneous nodule was 0.4 cm in size, firm, and movable without any change in the overlying skin. Recurrent PTC was confirmed after excision biopsy. Eight months after, she got a new nodule along the previous excision site. After punch biopsy, metastatic PTC was confirmed in the deep dermis and was re-excised with a clear resection margin. This is the first report of a case of solitary skin metastasis of PTC in Korea. Although solitary skin metastasis of PTC is rare, it should be considered in patients with a skin nodule.

Citations

Citations to this article as recorded by  

• Skin Metastasis Occurring 30 Years After Thyroidectomy for Papillary Thyroid Carcinoma
  Mohammed S Alwhaid, Olaa Mhish, Mutahir A Tunio, Salman AlMalki, Mushabbab Al Asiri, Khalid Al-Qahtani
  Cureus.2022;[Epub]     CrossRef
• Solitary Nasopharyngeal Metastasis From Papillary Thyroid Carcinoma Shown on FDG PET/CT
  Anqi Xu, Xiao Jie, Yan Xiu, Hongcheng Shi
  Clinical Nuclear Medicine.2022; 47(5): e425.     CrossRef
• PD-L1-positive Anaplastic Transformation in a BRAF V600E Expressing Papillary Thyroid Carcinoma with Cutaneous Metastasis: An Unusual Case Report
  Pooja Ramakant, Anand Mishra, Chanchal Rana, Kulranjan Singh
  Indian Journal of Endocrine Surgery and Research.2022; 17(1): 21.     CrossRef
• Unusual Thyroid Carcinoma Metastases: a Case Series and Literature Review
  Eleonora Farina, Fabio Monari, Giovanni Tallini, Andrea Repaci, Renzo Mazzarotto, Francesca Giunchi, Riccardo Panzacchi, Silvia Cammelli, Gilbert D. A. Padula, Francesco Deodato, Renato Pasquali, Stefano Fanti, Michelangelo Fiorentino, Alessio G. Morganti
  Endocrine Pathology.2016; 27(1): 55.     CrossRef
• Skin manifestations of endocrine and neuroendocrine tumors
  Jonathan S. Leventhal, Irwin M. Braverman
  Seminars in Oncology.2016; 43(3): 335.     CrossRef
• Isolated Metastasis in Male Breast from Differentiated Thyroid Carcinoma – Oncological Curiosity. A Case Report and Review of Literature
  Lakshminarasimman Parasuraman, Shubhada V. Kane, Prathamesh S. Pai, Kintan Shanghvi
  Indian Journal of Surgical Oncology.2016; 7(1): 91.     CrossRef
• A Closer Look at Papillary Thyroid Carcinoma
  Won Bae Kim
  Endocrinology and Metabolism.2015; 30(1): 1.     CrossRef
• Articles in 'Endocrinology and Metabolism' in 2014
  Won-Young Lee
  Endocrinology and Metabolism.2015; 30(1): 47.     CrossRef