- Type 2 Diabetes and Mitochondria.
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Hyo Jung Choo, Young Gyu Ko
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J Korean Endocr Soc. 2006;21(4):266-271. Published online August 1, 2006
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DOI: https://doi.org/10.3803/jkes.2006.21.4.266
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Abstract
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- Liver, muscle, and adipose tissue are resistant to insulin action in type 2 diabetes. In spite of intensive studies, few diabetic genes have been identified. Recently, mitochondrial impairment has been observed in the muscle and adipose tissues of type 2 diabetes patients, implying that mitochondrial dysfunction could be a pivotal factor in type 2 diabetes. Here, we discuss mitochondrial malfunction leading to type 2 diabetes.
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