Skip Navigation
Skip to contents

Endocrinol Metab : Endocrinology and Metabolism


Author index

Page Path
Elisa Ingargiola  (Ingargiola E) 1 Article
Adrenal gland
Is Follow-up of Adrenal Incidentalomas Always Mandatory?
Giuseppe Reimondo, Alessandra Muller, Elisa Ingargiola, Soraya Puglisi, Massimo Terzolo
Endocrinol Metab. 2020;35(1):26-35.   Published online March 19, 2020
  • 5,485 View
  • 224 Download
  • 5 Citations
AbstractAbstract PDFPubReader   ePub   CrossRef-TDMCrossref - TDM

Adrenal masses are mainly detected unexpectedly by an imaging study performed for reasons unrelated to any suspect of adrenal diseases. Such masses are commonly defined as “adrenal incidentalomas” and represent a public health challenge because they are increasingly recognized in current medical practice. Management of adrenal incidentalomas is currently matter of debate. Although there is consensus on the need of a multidisciplinary expert team evaluation and surgical approach in patients with significant hormonal excess and/or radiological findings suspicious of malignancy demonstrated at the diagnosis or during follow-up, the inconsistency between official guidelines and the consequent diffuse uncertainty on management of small adrenal incidentalomas still represents a considerable problem in terms of clinical choices in real practice. The aim of the present work is to review the proposed strategies on how to manage patients with adrenal incidentalomas that are not candidates to immediate surgery. The recent European Society of Endocrinology/European Network for the Study of Adrenal Tumors guidelines have supported the view to avoid surveillance in patients with clear benign adrenal lesions <4 cm and/or without any hormonal secretion; however, newer prospective studies are needed to confirm safety of this strategy, in particular in younger patients.


Citations to this article as recorded by  
  • Diagnosing and managing adrenal incidentalomas
    Justine Herndon, Irina Bancos
    JAAPA.2023; 36(5): 12.     CrossRef
  • Tumor enlargement in adrenal incidentaloma is related to glaucoma: a new prognostic feature?
    M. Caputo, T. Daffara, A. Ferrero, M. Romanisio, E. Monti, C. Mele, M. Zavattaro, S. Tricca, A. Siani, A. Clemente, C. Palumbo, S. De Cillà, A. Carriero, A. Volpe, P. Marzullo, G. Aimaretti, F. Prodam
    Journal of Endocrinological Investigation.2023;[Epub]     CrossRef
  • The Role of Biomarkers in Adrenocortical Carcinoma: A Review of Current Evidence and Future Perspectives
    Maja Mizdrak, Tina Tičinović Kurir, Joško Božić
    Biomedicines.2021; 9(2): 174.     CrossRef
  • An Adrenocortical Carcinoma Evolving After Nine Years of Latency From a Small Adrenal Incidentaloma
    Harpreet S Kohli, Sukesh Manthri, Shikha Jain, Rahul Kashyap, Sheng Chen, Thoyaja Koritala, Aysun Tekin, Ramesh Adhikari, Raghavendra Tirupathi, Aram Barbaryan, Simon Zec, Hanyin Wang, Stephanie Welle, Pavan Devulapally, Mack Sheraton, Manpreet Kaur, Vish
    Cureus.2021;[Epub]     CrossRef
  • Diagnostic algorithm of the subclinical forms of adrenal neoplasms
    Sofya G. Blyumina, Pavel N. Romashchenko, Igor S. Zheleznyak
    Bulletin of the Russian Military Medical Academy.2021; 23(3): 67.     CrossRef

Endocrinol Metab : Endocrinology and Metabolism