Skip Navigation
Skip to contents

Endocrinol Metab : Endocrinology and Metabolism

clarivate
OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > BROWSE ARTICLES > Author index
Search
Chan Kwon Jung  (Jung CK) 13 Articles
Thyroid
Utilizing Immunoglobulin G4 Immunohistochemistry for Risk Stratification in Patients with Papillary Thyroid Carcinoma Associated with Hashimoto Thyroiditis
Faridul Haq, Gyeongsin Park, Sora Jeon, Mitsuyoshi Hirokawa, Chan Kwon Jung
Endocrinol Metab. 2024;39(3):468-478.   Published online May 20, 2024
DOI: https://doi.org/10.3803/EnM.2024.1923
  • 1,679 View
  • 51 Download
AbstractAbstract PDFPubReader   ePub   
Background
Hashimoto thyroiditis (HT) is suspected to correlate with papillary thyroid carcinoma (PTC) development. While some HT cases exhibit histologic features of immunoglobulin G4 (IgG4)-related disease, the relationship of HT with PTC progression remains unestablished.
Methods
This cross-sectional study included 426 adult patients with PTC (≥1 cm) undergoing thyroidectomy at an academic thyroid center. HT was identified based on its typical histologic features. IgG4 and IgG immunohistochemistry were performed. Wholeslide images of immunostained slides were digitalized. Positive plasma cells per 2 mm2 were counted using QuPath and a pre-trained deep learning model. The primary outcome was tumor structural recurrence post-surgery.
Results
Among the 426 PTC patients, 79 were diagnosed with HT. With a 40% IgG4 positive/IgG plasma cell ratio as the threshold for diagnosing IgG4-related disease, a cutoff value of >150 IgG4 positive plasma cells per 2 mm2 was established. According to this criterion, 53% (43/79) of HT patients were classified as IgG4-related. The IgG4-related HT subgroup presented a more advanced cancer stage than the IgG4-non-related HT group (P=0.038). The median observation period was 109 months (range, 6 to 142). Initial assessment revealed 43 recurrence cases. Recurrence-free survival periods showed significant (P=0.023) differences, with patients with IgG4 non-related HT showing the longest period, followed by patients without HT and those with IgG4-related HT.
Conclusion
This study effectively stratified recurrence risk in PTC patients based on HT status and IgG4-related subtypes. These findings may contribute to better-informed treatment decisions and patient care strategies.
Close layer
Thyroid
A Narrative Review of the 2023 Korean Thyroid Association Management Guideline for Patients with Thyroid Nodules
Eun Kyung Lee, Young Joo Park, Chan Kwon Jung, Dong Gyu Na
Endocrinol Metab. 2024;39(1):61-72.   Published online February 14, 2024
DOI: https://doi.org/10.3803/EnM.2024.1938
  • 5,005 View
  • 352 Download
  • 2 Web of Science
  • 5 Crossref
AbstractAbstract PDFPubReader   ePub   
The 2023 Korean Thyroid Association (KTA) Management Guideline for Patients with Thyroid Nodules constitute an update of the 2016 KTA guideline for thyroid nodules and cancers that focuses specifically on nodules. The 2023 guideline aim to offer updated guidance based on new evidence that reflects the changes in clinical practice since the 2016 KTA guideline. To update the 2023 guideline, a comprehensive literature search was conducted from January 2022 to May 2022. The literature search included studies, reviews, and other evidence involving human subjects that were published in English in MEDLINE (PubMed), Embase, and other relevant databases. Additional significant clinical trials and research studies published up to April 2023 were also reviewed. The limitations of the current evidence are discussed, and suggestions for areas in need of further research are identified. The purpose of this review is to provide a summary of the 2023 KTA guideline for the management of thyroid nodules released in May 2023 and to give a balanced insight with comparison of recent guidelines from other societies.

Citations

Citations to this article as recorded by  
  • 2023 Update of the Korean Thyroid Association Guidelines for the Management of Thyroid Nodules
    Eun Kyung Lee, Young Joo Park
    Clinical Thyroidology®.2024; 36(4): 153.     CrossRef
  • Systemic therapy for differentiated thyroid cancer with distant metastasis
    Eun Kyung Lee
    Journal of the Korean Medical Association.2024; 67(7): 484.     CrossRef
  • Educational exchange in thyroid core needle biopsy diagnosis: enhancing pathological interpretation through guideline integration and peer learning
    Agnes Stephanie Harahap, Chan Kwon Jung
    Journal of Pathology and Translational Medicine.2024; 58(5): 205.     CrossRef
  • Standardized Ultrasound Evaluation for Active Surveillance of Low-Risk Thyroid Microcarcinoma in Adults: 2024 Korean Society of Thyroid Radiology Consensus Statement
    Ji Ye Lee, Min Kyoung Lee, Hyun Kyung Lim, Chang Yoon Lee, Jin Yong Sung, Jung Hyun Yoon, Soo Yeon Han, Jung Hee Shin, Ji-hoon Kim, So Lyung Jung, Sae Rom Chung, Jung Hwan Baek, Dong Gyu Na
    Korean Journal of Radiology.2024; 25(11): 942.     CrossRef
  • Thermal ablation for Bethesda III and IV thyroid nodules: current diagnosis and management
    Wen-Hui Chan, Pi-Ling Chiang, An-Ni Lin, Yen-Hsiang Chang, Wei-Che Lin
    Ultrasonography.2024; 43(6): 395.     CrossRef
Close layer
Thyroid
Frequency of TERT Promoter Mutations in Real-World Analysis of 2,092 Thyroid Carcinoma Patients (Endocrinol Metab 2022;37:652-63, Heera Yang et al.)
Sue Youn Kim, Chan Kwon Jung
Endocrinol Metab. 2022;37(6):947-948.   Published online November 10, 2022
DOI: https://doi.org/10.3803/EnM.2022.1596
  • 2,268 View
  • 166 Download
  • 3 Crossref
PDFPubReader   ePub   

Citations

Citations to this article as recorded by  
  • Korean Thyroid Association Guidelines on the Management of Differentiated Thyroid Cancers; Part I. Initial Management of Differentiated Thyroid Cancers - Chapter 5. Evaluation of Recurrence Risk Postoperatively and Initial Risk Stratification in Different
    Eun Kyung Lee, Young Shin Song, Ho-Cheol Kang, Sun Wook Kim, Dong Gyu Na, Shin Je Moon, Dong-Jun Lim, Kyong Yeun Jung, Yun Jae Chung, Chan Kwon Jung, Young Joo Park
    International Journal of Thyroidology.2024; 17(1): 68.     CrossRef
  • Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules 2024
    Young Joo Park, Eun Kyung Lee, Young Shin Song, Su Hwan Kang, Bon Seok Koo, Sun Wook Kim, Dong Gyu Na, Seung-Kuk Baek, So Won Oh, Min Kyoung Lee, Sang-Woo Lee, Young Ah Lee, Yong Sang Lee, Ji Ye Lee, Dong-Jun Lim, Leehi Joo, Yuh-Seog Jung, Chan Kwon Jung,
    International Journal of Thyroidology.2024; 17(1): 208.     CrossRef
  • 2023 Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules
    Young Joo Park, Eun Kyung Lee, Young Shin Song, Soo Hwan Kang, Bon Seok Koo, Sun Wook Kim, Dong Gyu Na, Seung-Kuk Baek, So Won Oh, Min Kyoung Lee, Sang-Woo Lee, Young Ah Lee, Yong Sang Lee, Ji Ye Lee, Dong-Jun Lim, Leehi Joo, Yuh-Seog Jung, Chan Kwon Jung
    International Journal of Thyroidology.2023; 16(1): 1.     CrossRef
Close layer
Thyroid
Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach
Chan Kwon Jung, Andrey Bychkov, Kennichi Kakudo
Endocrinol Metab. 2022;37(5):703-718.   Published online October 4, 2022
DOI: https://doi.org/10.3803/EnM.2022.1553
  • 26,126 View
  • 2,775 Download
  • 92 Web of Science
  • 106 Crossref
AbstractAbstract PDFPubReader   ePub   
The fifth edition of the World Health Organization (WHO) histologic classification of thyroid neoplasms released in 2022 includes newly recognized tumor types, subtypes, and a grading system. Follicular cell-derived neoplasms are categorized into three families (classes): benign tumors, low-risk neoplasms, and malignant neoplasms. The terms “follicular nodular disease” and “differentiated high-grade thyroid carcinoma” are introduced to account for multifocal hyperplastic/neoplastic lesions and differentiated thyroid carcinomas with high-grade features, respectively. The term “Hürthle cells” is replaced with “oncocytic cells.” Invasive encapsulated follicular and cribriform morular variants of papillary thyroid carcinoma (PTC) are now redefined as distinct tumor types, given their different genetic alterations and clinicopathologic characteristics from other PTC subtypes. The term “variant” to describe a subclass of tumor has been replaced with the term “subtype.” Instead, the term “variant” is reserved to describe genetic alterations. A histologic grading system based on the mitotic count, necrosis, and/or the Ki67 index is used to identify high-grade follicular-cell derived carcinomas and medullary thyroid carcinomas. The 2022 WHO classification introduces the following new categories: “salivary gland-type carcinomas of the thyroid” and “thyroid tumors of uncertain histogenesis.” This review summarizes the major changes in the 2022 WHO classification and their clinical relevance.

Citations

Citations to this article as recorded by  
  • Tumeurs de la thyroïde : nouveautés de la classification OMS 2022
    Serge Guyétant, Myriam Decaussin Petrucci, Emmanuelle Leteurtre
    Annales de Pathologie.2024; 44(1): 5.     CrossRef
  • Diagnostic Performance of [18F]TFB PET/CT Compared with Therapeutic Activity [131I]Iodine SPECT/CT and [18F]FDG PET/CT in Recurrent Differentiated Thyroid Carcinoma
    David Ventura, Matthias Dittmann, Florian Büther, Michael Schäfers, Kambiz Rahbar, Daniel Hescheler, Michael Claesener, Philipp Schindler, Burkhard Riemann, Robert Seifert, Wolfgang Roll
    Journal of Nuclear Medicine.2024; 65(2): 192.     CrossRef
  • Canine follicular cell and medullary thyroid carcinomas: Immunohistochemical characterization
    Jana Jankovic, Eve Tièche, Martina Dettwiler, Kerstin Hahn, Stephanie Scheemaeker, Martin Kessler, Sylvie Daminet, Sven Rottenberg, Miguel Campos
    Veterinary Pathology.2024; 61(4): 524.     CrossRef
  • Clinicopathological features of differentiated thyroid carcinoma as predictors of the effects of radioactive iodine therapy
    Wen Liu, Beibei Jiang, Jingli Xue, Ruijing Liu, Yuqing Wei, Peifeng Li
    Annals of Diagnostic Pathology.2024; 69: 152243.     CrossRef
  • Management of aggressive variants of papillary thyroid cancer
    Ying Ki Lee, Aleix Rovira, Paul V. Carroll, Ricard Simo
    Current Opinion in Otolaryngology & Head & Neck Surgery.2024; 32(2): 125.     CrossRef
  • Artificial Intelligence Detected the Relationship Between Nuclear Morphological Features and Molecular Abnormalities of Papillary Thyroid Carcinoma
    Toui Nishikawa, Ibu Matsuzaki, Ayata Takahashi, Iwamoto Ryuta, Fidele Yambayamba Musangile, Kanako Sagan, Mizuki Nishikawa, Yurina Mikasa, Yuichi Takahashi, Fumiyoshi Kojima, Shin-ichi Murata
    Endocrine Pathology.2024; 35(1): 40.     CrossRef
  • Review of the 2023 World Congress on Thyroid Cancer (WCTC 2023, London): is there light at the end of the tunnel for patients with neglected cancer?
    S.M. Cherenko
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2024; 19(8): 609.     CrossRef
  • Molecular Alterations and Comprehensive Clinical Management of Oncocytic Thyroid Carcinoma
    Lindsay A. Bischoff, Ian Ganly, Laura Fugazzola, Erin Buczek, William C. Faquin, Bryan R. Haugen, Bryan McIver, Caitlin P. McMullen, Kate Newbold, Daniel J. Rocke, Marika D. Russell, Mabel Ryder, Peter M. Sadow, Eric Sherman, Maisie Shindo, David C. Shonk
    JAMA Otolaryngology–Head & Neck Surgery.2024; 150(3): 265.     CrossRef
  • Malignancy in a Solitary Thyroid Nodule: A Retrospective Histopathological Evaluation
    Hassan Alzahrani
    International Journal of General Medicine.2024; Volume 17: 135.     CrossRef
  • Pathologie thyroïdienne. Actualités et problèmes pratiques. Introduction
    Serge Guyétant
    Annales de Pathologie.2024; 44(2): 90.     CrossRef
  • Diagnostic implication of thyroid spherules for cytological diagnosis of thyroid nodules
    Heeseung Sohn, Kennichi Kakudo, Chan Kwon Jung
    Cytopathology.2024; 35(3): 383.     CrossRef
  • Aggressive Primary Thyroid Mucoepidermoid Carcinoma with Extensive Pulmonary Involvement
    Marius Mitrache, Dana Terzea, Anca Sirbu, Simona Fica
    Biomedicines.2024; 12(2): 285.     CrossRef
  • Unravelling the role of long non-coding RNAs in modulating the Hedgehog pathway in cancer
    Shailendra Singh Chandel, Anurag Mishra, Gaurav Dubey, Ravindra Pal Singh, Mithilesh Singh, Mohit Agarwal, Himmat Singh Chawra, Neelima Kukreti
    Pathology - Research and Practice.2024; 254: 155156.     CrossRef
  • Hürthle cell (Oncocytic) carcinoma – Is hemithyroidectomy enough?
    Taylor O. Julsrud, Trenton R. Foster, Robert A. Vierkant, Melanie L. Lyden, Travis J. McKenzie, Mabel Ryder, Benzon M. Dy
    Surgical Oncology Insight.2024; 1(1): 100010.     CrossRef
  • Échographie des carcinomes thyroïdiens différenciés de souche folliculaire
    P.Y. Marcy, M. Tassart, J.G. Marchand, J. Sanglier, A. Bizeau, E. Ghanassia
    Journal d'imagerie diagnostique et interventionnelle.2024; 7(2): 54.     CrossRef
  • Differentiating BRAF V600E- and RAS-like alterations in encapsulated follicular patterned tumors through histologic features: a validation study
    Chankyung Kim, Shipra Agarwal, Andrey Bychkov, Jen-Fan Hang, Agnes Stephanie Harahap, Mitsuyoshi Hirokawa, Kennichi Kakudo, Somboon Keelawat, Chih-Yi Liu, Zhiyan Liu, Truong Phan-Xuan Nguyen, Chanchal Rana, Huy Gia Vuong, Yun Zhu, Chan Kwon Jung
    Virchows Archiv.2024; 484(4): 645.     CrossRef
  • Cas no5. High-grade Tall cell papillary carcinoma
    Myriam Decaussin-Petrucci
    Annales de Pathologie.2024; 44(2): 114.     CrossRef
  • Primary Squamous Cell Carcinoma of the Thyroid Has a Molecular Genetic Profile Distinct From That of Anaplastic Thyroid Carcinoma
    Meihua Ye, Zhenying Guo, Jingjing Xu, Yanling Jin, Xianglei He, Minghua Ge
    American Journal of Surgical Pathology.2024; 48(8): 1024.     CrossRef
  • Current and future of immunotherapy for thyroid cancer based on bibliometrics and clinical trials
    Ke Wang, Ying Zhang, Yang Xing, Hong Wang, Minghua He, Rui Guo
    Discover Oncology.2024;[Epub]     CrossRef
  • Cas no6. Anaplastic thyroid carcinoma, epidermoid subtype
    Myriam Decaussin-Petrucci
    Annales de Pathologie.2024; 44(2): 120.     CrossRef
  • Papillary Thyroid Carcinoma With Lymphoepithelial Features and Lacking Association With Epstein-Barr Virus (EBV): A Rare Case
    Ahmed Bendari, Saroja Devi Geetha, Reham Al-Refai, Xuelin Zhong, Sunder Sham, Manju Harshan
    Cureus.2024;[Epub]     CrossRef
  • Clinical and morphological features and unsolved issues in diagnosis of aggressive forms of papillary thyroid carcinoma
    Denis V. Korotovsky, Sergey V. Sergiiko, Sergey A. Lukyanov
    Perm Medical Journal.2024; 41(1): 90.     CrossRef
  • Finding possible diagnostic markers for differentiating benign and malignant thyroid tumors on example investigate of rheological properties1
    I. Javakhishvili, T. Sanikidze, K. Mardaleishvili, N. Momtselidze, T. Urdulashvili, M. Mantskava, L. Prantl, F. Jung
    Clinical Hemorheology and Microcirculation.2024; 87(4): 515.     CrossRef
  • Unraveling the Significance of DGCR8 and miRNAs in Thyroid Carcinoma
    Lia Rodrigues, Arnaud Da Cruz Paula, Paula Soares, João Vinagre
    Cells.2024; 13(7): 561.     CrossRef
  • Management of Poorly Differentiated Thyroid Cancer and Differentiated High-Grade Thyroid Carcinoma
    Iram S. Alam, Kepal N. Patel
    Surgical Clinics of North America.2024; 104(4): 751.     CrossRef
  • What’s new in thyroid pathology 2024: updates from the new WHO classification and bethesda system
    Andrey Bychkov, Chan Kwon Jung
    Journal of Pathology and Translational Medicine.2024; 58(2): 98.     CrossRef
  • Ultrasound–Histopathological Presentation of Thyroid and Ovary Lesions in Adolescent Patients with DICER1 Syndrome: Case Reports and Literature Overview
    Dominika Januś, Monika Kujdowicz, Konrad Kaleta, Kamil Możdżeń, Jan Radliński, Anna Taczanowska-Niemczuk, Aleksandra Kiszka-Wiłkojć, Marcin Maślanka, Wojciech Górecki, Jerzy B. Starzyk
    Children.2024; 11(4): 403.     CrossRef
  • Surgical treatment of solid variant of papillary thyroid carcinoma: Fifteen-year experience of a tertiary center
    Katarina Tausanović, Marina Stojanović, Milan Jovanović, Boban Stepanović, Jovan Ilić, Sara Ivaniš, Vladan Živaljević
    Medicinska istrazivanja.2024; 57(1): 121.     CrossRef
  • Critical appraisal of the WHO 2022 classification of thyroid cancer
    Mithraa Devi Sekar, Debasis Gochhait, Sadishkumar Kamalanathan
    Thyroid Research and Practice.2024;[Epub]     CrossRef
  • Patterns in the Reporting of Aggressive Histologic Subtypes in Papillary Thyroid Cancer
    Yeon J. Lee, Caitlin E. Egan, Jacques A. Greenberg, Teagan Marshall, Abhinay Tumati, Brendan M. Finnerty, Toni Beninato, Rasa Zarnegar, Thomas J. Fahey, Minerva A. Romero Arenas
    Journal of Surgical Research.2024; 298: 325.     CrossRef
  • An individualized protein-based prognostic model to stratify pediatric patients with papillary thyroid carcinoma
    Zhihong Wang, He Wang, Yan Zhou, Lu Li, Mengge Lyu, Chunlong Wu, Tianen He, Lingling Tan, Yi Zhu, Tiannan Guo, Hongkun Wu, Hao Zhang, Yaoting Sun
    Nature Communications.2024;[Epub]     CrossRef
  • Clinical and Paraclinical Considerations Regarding ki67’s Role in the Management of Differentiated Thyroid Carcinoma—A Literature Review
    Claudiu Peștean, Alexandru Pavel, Doina Piciu
    Medicina.2024; 60(5): 769.     CrossRef
  • Can the analysis of chromatin texture and nuclear fractal dimensions serve as effective means to distinguish non-invasive follicular thyroid neoplasm with papillary-like nuclear features from other malignancies with follicular pattern in the thyroid?: a s
    Geet Bhuyan, Anjumoni Rabha
    Ultrastructural Pathology.2024; 48(4): 310.     CrossRef
  • A Comprehensive Review and Insights into the New Entity of Differentiated High-Grade Thyroid Carcinoma
    Agnes Stephanie Harahap, Regina Stefani Roren, Shofiyya Imtiyaz
    Current Oncology.2024; 31(6): 3311.     CrossRef
  • Predictive Factors of Radioactive Iodine Therapy Refractoriness in Patients with Differentiated Thyroid Carcinoma
    Majdouline Bel Lakhdar, Ayat Mouaden, Mourad Zekri, Dounia Alami, Hamza Zarouf, Imad Ghfir, Hasnae Guerrouj
    World Journal of Nuclear Medicine.2024; 23(03): 185.     CrossRef
  • Korean Thyroid Association Guidelines on the Management of Differentiated Thyroid Cancers; Part I. Initial Management of Differentiated Thyroid Cancers - Chapter 4. Pathological Diagnosis and Staging after Thyroidectomy 2024
    Su-Jin Shin, Hee Young Na, Ho-Cheol Kang, Sun Wook Kim, Dong Gyu Na, Young Joo Park, Young Shin Song, Eun Kyung Lee, Dong-Jun Lim, Yun Jae Chung, Chan Kwon Jung
    International Journal of Thyroidology.2024; 17(1): 61.     CrossRef
  • Management of Parapharyngeal Metastatic Medullary Thyroid Carcinoma Via a Combined Trans-Cervical and Trans-Oral Robotic Approach
    Clémentine Hyvrard, Florent Couineau, Tiffany Rigal, Serena Louerat, Stéphane Hans, Robin Baudouin
    Annals of Otology, Rhinology & Laryngology.2024; 133(9): 823.     CrossRef
  • Eggshell Calcifications at Thyroid Ultrasound: A Sample-focused Analysis of Cytological Findings and Post-thyroidectomy Pathological Correlates
    Florentina Ioniţă Radu, Ana M. Gheorghe , Oana C. Sima , Mara Carsote , Claudiu Nistor
    Romanian Journal of Military Medicine.2024; 127(6): 428.     CrossRef
  • Biomarkers in Thyroid Cancer: Emerging Opportunities from Non-Coding RNAs and Mitochondrial Space
    Patricio Cabané, Claudio Correa, Ignacio Bode, Rodrigo Aguilar, Alvaro A. Elorza
    International Journal of Molecular Sciences.2024; 25(12): 6719.     CrossRef
  • Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks
    Wenjing Chen, Young Shin Song, Han Sai Lee, Chien-Wei Lin, Junguee Lee, Yea Eun Kang, Seon-Kyu Kim, Seon-Young Kim, Young Joo Park, Jong-In Park
    Oncogene.2024; 43(31): 2431.     CrossRef
  • Utilizing Immunoglobulin G4 Immunohistochemistry for Risk Stratification in Patients with Papillary Thyroid Carcinoma Associated with Hashimoto Thyroiditis
    Faridul Haq, Gyeongsin Park, Sora Jeon, Mitsuyoshi Hirokawa, Chan Kwon Jung
    Endocrinology and Metabolism.2024; 39(3): 468.     CrossRef
  • The Role of SPECT/CT and PET/CT Hybrid Imaging in the Management of Ectopic Thyroid Carcinoma—A Systematic Review
    Claudiu Peștean, Alexandru Pavel, Doina Piciu
    Diagnostics.2024; 14(13): 1369.     CrossRef
  • Long-term survival outcomes of systemic therapy in patients with isolated and mixed medullary thyroid cancer
    Manal S. Fawzy, Aziza Ali Alenezi, Baraah T. Abu AlSel, Eman A. Toraih
    Heliyon.2024; 10(13): e33654.     CrossRef
  • Radioactive iodine therapy for thyroid cancer coexisting with Hashimoto’s thyroiditis: a systematic review and meta-analysis
    Xiang-Yi Chen, Yang Tan, Dawei Wang, Zhi-Xiao Wei
    British Journal of Radiology.2024; 97(1160): 1423.     CrossRef
  • Advances in clinical research on ultrasound-guided radiofrequency ablation for papillary thyroid microcarcinoma
    Hua Xu, Jin-yan Yang, Xing Zhao, Zhe Ma
    Frontiers in Oncology.2024;[Epub]     CrossRef
  • Proteomics profile in encapsulated follicular patterned thyroid neoplasms
    Truong Phan-Xuan Nguyen, Sittiruk Roytrakul, Supranee Buranapraditkun, Shanop Shuangshoti, Nakarin Kitkumthorn, Somboon Keelawat
    Scientific Reports.2024;[Epub]     CrossRef
  • Understanding the factors of wearable devices among the patients with thyroid cancer: A modified UTAUT2 model
    LingLi Song, BinXian Li, HaiBo Wu, CuiCui Wu, XueQi Zhang, Zhiyuan Yu
    PLOS ONE.2024; 19(7): e0305944.     CrossRef
  • Warthin like papillary thyroid carcinoma: A rare case report
    Anjali Goyal, Riya Shah, Monali Halpati, Kinjal Damor, Prahari Nayankumar Updhyaya
    IP Journal of Diagnostic Pathology and Oncology.2024; 9(2): 134.     CrossRef
  • Simultaneous occurrence of papillary thyroid carcinoma, medullary thyroid carcinoma, and lymphoma: A case report
    Zengfang Hao, Hanjing Cui, Yuehong Li, Wenxin Wu, Yuan Wang, Haijun Dan, Lei Lou, Hengshu Wang, Pengxin Zhao
    Medicine.2024; 103(33): e39363.     CrossRef
  • Emerging Strategies in Thyroid Cancer Immunotherapy: A Comprehensive Systematic Review and Meta-Analysis of Clinical Outcomes
    Daniel Alejandro Estrella Cornejo, Meylin Yalitza Carriel Alvarado, Norma Susana Chávez Villagómez, Alberto Dario Díaz Parra, María Fernanda Navas Espinosa
    Salud, Ciencia y Tecnología.2024; 4: 1241.     CrossRef
  • Advances in the Diagnosis and Treatment of Follicular Thyroid Carcinoma: A Comprehensive Review
    Vasundara Gopalan, Swati G Deshpande, Anup A Zade, Darshana Tote, Rahul Rajendran, Shubham Durge, Abhilasha Bhargava
    Cureus.2024;[Epub]     CrossRef
  • WHO 2022 updates on follicular cell and c-cell derived thyroid neoplasm
    Parth Goswami, Tarang Patel, Rushang Dave, Gyanendra Singh, Anurag Singh, Tushar Kalonia
    Journal of Medicine and Life.2024; 17(1): 15.     CrossRef
  • Oncocytic Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: A Case Report
    Kaveripakam Ajay Joseph, Sana Ahuja, Sufian Zaheer
    Indian Journal of Surgical Oncology.2024;[Epub]     CrossRef
  • Enhancing diagnostic precision in thyroid nodule assessment: evaluating the efficacy of a novel cell preservation technique in fine-needle aspiration cytology
    Diana-Raluca Streinu, Octavian Constantin Neagoe, Andreea Borlea, Ion Icma, Mihnea Derban, Dana Stoian
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Prognosis of Poorly Differentiated Thyroid Carcinoma: A Systematic Review and Meta-Analysis
    Ji Young Kim, Jae Kyung Myung, Soyun Kim, Kyung Tae, Yun Young Choi, Soo Jin Lee
    Endocrinology and Metabolism.2024; 39(4): 590.     CrossRef
  • Comparing therapeutic outcomes: radioactive iodine therapy versus non-radioactive iodine therapy in differentiated thyroid cancer
    Robert Aurelian Tiucă, Oana Mirela Tiucă, Raluca Monica Pop, Ionela Maria Paşcanu
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Solitär fibröser Tumor in einem follikulären Adenom der Schilddrüse
    Sarah Theurer, Simon Schimmack, Hideo A. Baba
    Die Pathologie.2024; 45(6): 404.     CrossRef
  • Dihydroartemisinin Inhibits Epithelial–Mesenchymal Transition Progression in Medullary Thyroid Carcinoma Through the Hippo Signaling Pathway Regulated by Interleukin-6
    Ruicong Li, Xinyu Zhang, Yanan Ge, Zhen Zhao, Liangliang Feng, Xiaoming Li
    Cancer Biotherapy and Radiopharmaceuticals.2024;[Epub]     CrossRef
  • Educational exchange in thyroid core needle biopsy diagnosis: enhancing pathological interpretation through guideline integration and peer learning
    Agnes Stephanie Harahap, Chan Kwon Jung
    Journal of Pathology and Translational Medicine.2024; 58(5): 205.     CrossRef
  • Neoadjuvant Treatment in Locally Advanced Thyroid Carcinoma
    Víctor Navas Moreno, Fernando Sebastián Valles, Marcos Lahera Vargas, Berta Hernández Marín, Elena Carrillo López, Mónica Marazuela, José Luis Muñoz de Nova
    Journal of Clinical Medicine.2024; 13(19): 5769.     CrossRef
  • SEOM-GETNE-TTCC Clinical guideline thyroid cancer (2023)
    Teresa Alonso-Gordoa, Paula Jimenez-Fonseca, Javier Martinez-Trufero, Miguel Navarro, Ignacio Porras, Jordi Rubió-Casadevall, Marta Arregui Valles, Neus Basté, Jorge Hernando, Lara Iglesias Docampo
    Clinical and Translational Oncology.2024; 26(11): 2902.     CrossRef
  • CYTOLOGICAL DIAGNOSTICS OF THYROID DISEASES: BASIC PRINCIPLES AND FEATURES OF APPLICATION IN MODERN CONDITIONS
    V. I. Vovk
    Ukrainian Journal of Laboratory Medicine.2024;[Epub]     CrossRef
  • PET/CT imaging of differentiated and medullary thyroid carcinoma using the novel SSTR-targeting peptide [18F]SiTATE – first clinical experiences
    Sophie C. Kunte, Vera Wenter, Johannes Toms, Simon Lindner, Marcus Unterrainer, Friederike Eilsberger, Klaus Jurkschat, Carmen Wängler, Björn Wängler, Ralf Schirrmacher, Maximilian W. Tiling, Gabriel T. Sheikh, Dirk Mehrens, Matthias Brendel, Johannes Rüb
    European Journal of Nuclear Medicine and Molecular Imaging.2024;[Epub]     CrossRef
  • Coexisting Medullary and Papillary Thyroid Carcinomas: A Case of Dual Neoplasia With a High Risk of Misdiagnosis
    Santiago Sierra Castillo, Maria A Henao Rincón, David Aristizabal Colorado, David Alexander Vernaza Trujillo, Alin Abreu Lomba
    Cureus.2024;[Epub]     CrossRef
  • Complexities in diagnosis and treatment of medullary thyroid cancer. Clinical observation
    E. V. Frolova, N. N. Naumova, E. V. Salautin, E. A. Volodina
    Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH).2024; 14(4): 99.     CrossRef
  • Unifocal Conventional Papillary Thyroid Carcinoma with Coexisting Caseating Granulomatous Inflammation in India
    Umasankary Calaisselvane, Banushree Chandrasekhar Srinivasamurthy, Mima Maychet B. Sangma, M. Shyamala Gowri
    Indian Journal of Otolaryngology and Head & Neck Surgery.2024;[Epub]     CrossRef
  • Nomogram predicts cervical lymph node metastasis of pathological subtypes of papillary thyroid carcinoma
    Ziyu Luo, Wenhan Li, Binliang Huo, Jianhui Li
    Langenbeck's Archives of Surgery.2024;[Epub]     CrossRef
  • High-grade encapsulated follicular cell thyroid carcinomas
    A.Yu. Abrosimov, A.A. Kuryshev
    Russian Journal of Archive of Pathology.2024; 86(5): 60.     CrossRef
  • Nouveautés en pathologie thyroïdienne : classification OMS 2022, système Bethesda 2023, biologie moléculaire et testing moléculaire
    Mohamed Amine Bani, Sophie Moog, Voichita Suciu, Livia Lamartina, Abir Al Ghuzlan
    Bulletin du Cancer.2024; 111(10): 10S5.     CrossRef
  • Histopathological Analysis of Thyroid Nodules with Taller-Than-Wide Shape in Adults
    Xi-Yue Yang, Li-Fang Huang, Yue-Jian Han, Xiao-Xin Cen, Zong-Xin Tao
    International Journal of General Medicine.2024; Volume 17: 5123.     CrossRef
  • Update on C-Cell Neuroendocrine Neoplasm: Prognostic and Predictive Histopathologic and Molecular Features of Medullary Thyroid Carcinoma
    Chan Kwon Jung, Shipra Agarwal, Jen-Fan Hang, Dong-Jun Lim, Andrey Bychkov, Ozgur Mete
    Endocrine Pathology.2023; 34(1): 1.     CrossRef
  • The 5th edition of WHO classification of tumors of endocrine organs: changes in the diagnosis of follicular-derived thyroid carcinoma
    Fulvio Basolo, Elisabetta Macerola, Anello Marcello Poma, Liborio Torregrossa
    Endocrine.2023; 80(3): 470.     CrossRef
  • Preoperative Risk Stratification of Follicular-patterned Thyroid Lesions on Core Needle Biopsy by Histologic Subtyping and RAS Variant-specific Immunohistochemistry
    Meejeong Kim, Sora Jeon, Chan Kwon Jung
    Endocrine Pathology.2023; 34(2): 247.     CrossRef
  • Ultrasound evolution of parenchymal changes in the thyroid gland with autoimmune thyroiditis in children prior to the development of papillary thyroid carcinoma – a follow-up study
    Dominika Januś, Monika Kujdowicz, Małgorzata Wójcik, Anna Taczanowska-Niemczuk, Aleksandra Kiszka-Wiłkojć, Wojciech Górecki, Jerzy B. Starzyk
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Papillary thyroid carcinoma with aggressive fused follicular and solid growth pattern: A unique histological subtype with high‐grade malignancy?
    Shin‐ichi Murata, Ibu Matsuzaki, Mitsuo Kishimoto, Naomi Katsuki, Toshinori Onishi, Mitsuyoshi Hirokawa, Fumiyoshi Kojima
    Pathology International.2023; 73(5): 207.     CrossRef
  • Multi-Omics and Management of Follicular Carcinoma of the Thyroid
    Thifhelimbilu Emmanuel Luvhengo, Ifongo Bombil, Arian Mokhtari, Maeyane Stephens Moeng, Demetra Demetriou, Claire Sanders, Zodwa Dlamini
    Biomedicines.2023; 11(4): 1217.     CrossRef
  • Molecular Genetics of Diffuse Sclerosing Papillary Thyroid Cancer
    Meshael Alswailem, Balgees Alghamdi, Anwar Alotaibi, Abeer Aljomiah, Hindi Al-Hindi, Avaniyapuram Kannan Murugan, Mohamed Abouelhoda, Yufei Shi, Ali S Alzahrani
    The Journal of Clinical Endocrinology & Metabolism.2023; 108(9): e704.     CrossRef
  • Multifunctional Phase-Transition Nanoparticles for Effective Targeted Sonodynamic-Gene Therapy Against Thyroid Papillary Carcinoma
    Shihui Guan, Dengke Teng, Hui Wang, Qimeihui Wang, Xi Zhen, Guoqing Sui, Yang Wang, Lingyu Zhu, Yuanqiang Lin, Dan Jiao, Feng Guo
    International Journal of Nanomedicine.2023; Volume 18: 2275.     CrossRef
  • Utilizing Dynamic Risk Stratification in Patients With Tall Cell Variant Papillary Thyroid Cancer
    David Zimmer, Gilman Plitt, Brandon Prendes, Jamie Ku, Natalie Silver, Eric Lamarre, Emrullah Yilmaz, Jessica Geiger, Christian Nasr, Lea El Hage, Mario Skugor, Shauna Cambpell, Shlomo Koyfman, Jacob Miller, Neil Woody, Katherine Heiden, Nikhil Joshi, Tar
    The Laryngoscope.2023; 133(9): 2430.     CrossRef
  • Ultrasound, laboratory and histopathological insights in diagnosing papillary thyroid carcinoma in a paediatric population: a single centre follow-up study between 2000-2022
    Dominika Januś, Małgorzata Wójcik, Anna Taczanowska-Niemczuk, Aleksandra Kiszka-Wiłkojć, Monika Kujdowicz, Małgorzata Czogała, Wojciech Górecki, Jerzy B. Starzyk
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Medullary Thyroid Carcinoma: A Single Institute Experience
    Sonal Trivedi, T. Salahuddin, Mohamed Taher Mithi, Priyank Rathod, Arpit Bandi, Shashank J. Pandya, Mohit Sharma, Shailesh Patel, Vikas Warikoo, Ketul Puj, Abhijeet Salunkhe, Keval Patel, Shivam Pandya
    Indian Journal of Otolaryngology and Head & Neck Surgery.2023; 75(4): 2884.     CrossRef
  • FNAC (Fine needle aspiration cytology) and histopathological correlation and reclassification of thyroid neoplasm in accordance with WHO classification 2022
    Fareeda Joshi, Shreya Hegde
    Indian Journal of Pathology and Oncology.2023; 10(2): 132.     CrossRef
  • Papillary thyroid carcinoma associated with non‑functioning parathyroid carcinoma with Warthin's tumor of the parotid gland: A case report and brief literature review
    Ari Abdullah, Aras Qaradakhy, Yadgar Saeed, Abdulwahid Salih, Seema Karim, Osama Ali, Shko Hassan, Shalaw Nasraldeen, Shvan Mohammed, Fahmi Kakamad
    Medicine International.2023;[Epub]     CrossRef
  • Warthin-like papillary thyroid carcinoma: a case report and comprehensive review of the literature
    Abdel Mouhaymen Missaoui, Fatma Hamza, Wafa Belabed, Manel Mellouli, Mohamed Maaloul, Slim Charfi, Issam Jardak, Tahya Sellami-Boudawara, Nabila Rekik, Mohamed Abid
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Reevaluating diagnostic categories and associated malignancy risks in thyroid core needle biopsy
    Chan Kwon Jung
    Journal of Pathology and Translational Medicine.2023; 57(4): 208.     CrossRef
  • Cancer Predisposition Syndromes and Thyroid Cancer: Keys for a Short Two-Way Street
    Ioana Balinisteanu, Monica-Cristina Panzaru, Lavinia Caba, Maria-Christina Ungureanu, Andreea Florea, Ana Maria Grigore, Eusebiu Vlad Gorduza
    Biomedicines.2023; 11(8): 2143.     CrossRef
  • Deep learning prediction model for central lymph node metastasis in papillary thyroid microcarcinoma based on cytology
    Wenhao Ren, Yanli Zhu, Qian Wang, Yuntao Song, Zhihui Fan, Yanhua Bai, Dongmei Lin
    Cancer Science.2023; 114(10): 4114.     CrossRef
  • Cytology and Histology of Thyroid Nodules: Exploring Novel Insights in the Molecular Era for Enhanced Patient Management
    Beatrix Cochand-Priollet, Zahra Maleki
    Current Oncology.2023; 30(8): 7753.     CrossRef
  • Agrin is a novel oncogenic protein in thyroid cancer
    Anna Adamiok‑Ostrowska, Małgorzata Grzanka, Barbara Czarnocka
    Oncology Letters.2023;[Epub]     CrossRef
  • Analysis of Pathological Features of Thyroid Carcinoma in the Western Yunnan
    身吾 王
    Advances in Clinical Medicine.2023; 13(10): 15820.     CrossRef
  • Insight of novel biomarkers for papillary thyroid carcinoma through multiomics
    Wei Liu, Junkan Zhu, Zhen Wu, Yongxiang Yin, Qiao Wu, Yiming Wu, Jiaojiao Zheng, Cong Wang, Hongyan Chen, Talal Jamil Qazi, Jun Wu, Yuqing Zhang, Houbao Liu, Jingmin Yang, Daru Lu, Xumin Zhang, Zhilong Ai
    Frontiers in Oncology.2023;[Epub]     CrossRef
  • Identification of NIFTP-Specific mRNA Markers for Reliable Molecular Diagnosis of Thyroid Tumors
    So-Yeon Lee, Jong-Lyul Park, Kwangsoon Kim, Ja Seong Bae, Jae-Yoon Kim, Seon-Young Kim, Chan Kwon Jung
    Endocrine Pathology.2023; 34(3): 311.     CrossRef
  • Somatostatin Receptor Type 2 and Thyroid-Stimulating Hormone Receptor Expression in Oncocytic Thyroid Neoplasms: Implications for Prognosis and Treatment
    Andrea Gillis, Rui Zheng-Pywell, Chandler McLeod, Dezhi Wang, John M. Ness, Rachael Guenter, Jason Whitt, Tomas A. Prolla, Herbert Chen, Manuel Lora Gonzalez, Bart Rose, Ricardo V. Lloyd, Renata Jaskula-Sztul, Diana Lin
    Modern Pathology.2023; 36(12): 100332.     CrossRef
  • Comparison of Treatment and Prognosis Between Follicular Variant Papillary Thyroid Carcinoma and Classical Papillary Thyroid Carcinoma
    Bing Zhang, Wenming Wu, Jinjing Liu, Zhou Liang, Liang Zong
    Hormone and Metabolic Research.2023; 55(12): 855.     CrossRef
  • Sentinel lymph node mapping: current applications and future perspectives in thyroid carcinoma
    Isabella Merante Boschin, Loris Bertazza, Carla Scaroni, Caterina Mian, Maria Rosa Pelizzo
    Frontiers in Medicine.2023;[Epub]     CrossRef
  • Utility of the Growth Differentiation Factor-15 in the Differential Diagnosis of Follicular-Patterned Lesions of the Thyroid on Cytopathologic and Histopathologic Samples
    Prasanna V Perumal, Neelaiah Siddaraju, Sunil K Saxena, Soundravally Rajendiran, Ramachandra V Bhat
    Cureus.2023;[Epub]     CrossRef
  • Investigation of pre‐operative demographic, biochemical, sonographic and cytopathological findings in low‐risk thyroid neoplasms
    Muzaffer Serdar Deniz, Didem Özdemir, Narin Nasıroğlu İmga, Hüsniye Başer, Fatma Neslihan Çuhacı Seyrek, Ayşegül Aksoy Altınboğa, Oya Topaloğlu, Reyhan Ersoy, Bekir Çakır
    Clinical Endocrinology.2023; 99(5): 502.     CrossRef
  • Applications of machine and deep learning to thyroid cytology and histopathology: a review
    Greg Slabaugh, Luis Beltran, Hasan Rizvi, Panos Deloukas, Eirini Marouli
    Frontiers in Oncology.2023;[Epub]     CrossRef
  • The Asian Thyroid Working Group, from 2017 to 2023
    Kennichi Kakudo, Chan Kwon Jung, Zhiyan Liu, Mitsuyoshi Hirokawa, Andrey Bychkov, Huy Gia Vuong, Somboon Keelawat, Radhika Srinivasan, Jen-Fan Hang, Chiung-Ru Lai
    Journal of Pathology and Translational Medicine.2023; 57(6): 289.     CrossRef
  • Anaplastic thyroid cancer: Pathogenesis, prognostic factors and genetic landscape (Review)
    Abdul-Mohsen Alhejaily, Omar Alhuzim, Yazeed Alwelaie
    Molecular and Clinical Oncology.2023;[Epub]     CrossRef
  • Simultaneous Occurrence of Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma: A Case Series with Literature Review
    Poupak Fallahi, Armando Patrizio, Giulio Stoppini, Giusy Elia, Francesca Ragusa, Sabrina Rosaria Paparo, Eugenia Balestri, Valeria Mazzi, Chiara Botrini, Gilda Varricchi, Salvatore Ulisse, Marco Ghionzoli, Alessandro Antonelli, Silvia Martina Ferrari
    Current Oncology.2023; 30(12): 10237.     CrossRef
  • Construction and validation of a nomogram for predicting cervical lymph node metastasis in diffuse sclerosing variant of papillary thyroid carcinoma
    Xunyi Lin, Jiaxing Huo, Huan Zhang, Hang Su, Fenghua Zhang
    Langenbeck's Archives of Surgery.2023;[Epub]     CrossRef
  • A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma
    Julia I. Staubitz-Vernazza, Sina Schwind, Oana Lozan, Thomas J. Musholt
    Cancers.2023; 16(1): 163.     CrossRef
  • Reprogramming of Cellular Metabolism and Its Therapeutic Applications in Thyroid Cancer
    Yuji Nagayama, Koichiro Hamada
    Metabolites.2022; 12(12): 1214.     CrossRef
  • Developments to improve outcomes in thyroid surgery
    Thomas J. Musholt
    Innovative Surgical Sciences.2022; 7(3-4): 77.     CrossRef
  • The relationship of the clinicopathological characteristics and treatment results of post-Chornobyl papillary thyroid microcarcinomas with the latency period and radiation exposure
    Tetiana Bogdanova, Serhii Chernyshov, Liudmyla Zurnadzhy, Tatiana I. Rogounovitch, Norisato Mitsutake, Mykola Tronko, Masahiro Ito, Michael Bolgov, Sergii Masiuk, Shunichi Yamashita, Vladimir A. Saenko
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
Close layer
Thyroid
Re-Increasing Trends in Thyroid Cancer Incidence after a Short Period of Decrease in Korea: Reigniting the Debate on Ultrasound Screening
Chan Kwon Jung, Ja Seong Bae, Young Joo Park
Endocrinol Metab. 2022;37(5):816-818.   Published online October 11, 2022
DOI: https://doi.org/10.3803/EnM.2022.1586
  • 2,819 View
  • 184 Download
  • 7 Web of Science
  • 8 Crossref
PDFPubReader   ePub   

Citations

Citations to this article as recorded by  
  • Bilateral axillo-breast approach robotic total thyroidectomy without isthmectomy: a case report
    Hyeji Kim, Hyeonuk Hwang, Hyungju Kwon
    The Ewha Medical Journal.2024;[Epub]     CrossRef
  • Contents analysis of thyroid cancer-related information uploaded to YouTube by physicians in Korea: endorsing thyroid cancer screening, potentially leading to overdiagnosis
    EunKyo Kang, HyoRim Ju, Soojeong Kim, Juyoung Choi
    BMC Public Health.2024;[Epub]     CrossRef
  • Cost-Utility Analysis of Early Detection with Ultrasonography of Differentiated Thyroid Cancer: A Retrospective Study on a Korean Population
    Han-Sang Baek, Jeonghoon Ha, Kwangsoon Kim, Ja Seong Bae, Jeong Soo Kim, Sungju Kim, Dong-Jun Lim, Chul-Min Kim
    Endocrinology and Metabolism.2024; 39(2): 310.     CrossRef
  • Thyroid Cancer Incidence Among Korean Individuals: A Comparison of South Korea and the United States
    Dohun Kim, Guan Li, Peter K. Moon, Yifei Ma, Soohyun Sim, Sung Y. Park, Minkyung Oh, Uchechukwu C. Megwalu
    The Laryngoscope.2024; 134(9): 4156.     CrossRef
  • Thyroid cancer-specific mortality during 2005–2018 in Korea, aftermath of the overdiagnosis issue: a nationwide population-based cohort study
    Kyeong Jin Kim, Jimi Choi, Sue K. Park, Young Joo Park, Sin Gon Kim
    International Journal of Surgery.2024; 110(9): 5489.     CrossRef
  • Survival Comparison of Incidentally Found versus Clinically Detected Thyroid Cancers: An Analysis of a Nationwide Cohort Study
    Shinje Moon, Eun Kyung Lee, Hoonsung Choi, Sue K. Park, Young Joo Park
    Endocrinology and Metabolism.2023; 38(1): 81.     CrossRef
  • Cumulative exposure to metabolic syndrome increases thyroid cancer risk in young adults: a population-based cohort study
    Jinyoung Kim, Kyungdo Han, Mee Kyoung Kim, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
    The Korean Journal of Internal Medicine.2023; 38(4): 526.     CrossRef
  • Cost-Effectiveness of Active Surveillance Compared to Early Surgery of Small Papillary Thyroid Cancer: A Retrospective Study on a Korean Population
    Han-Sang Baek, Jeonghoon Ha, Kwangsoon Kim, Jaseong Bae, Jeong Soo Kim, Sungju Kim, Dong-Jun Lim, Chulmin Kim
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
Close layer
Thyroid
Diagnostic Performance of Thyroid Core Needle Biopsy Using the Revised Reporting System: Comparison with Fine Needle Aspiration Cytology
Kwangsoon Kim, Ja Seong Bae, Jeong Soo Kim, So Lyung Jung, Chan Kwon Jung
Endocrinol Metab. 2022;37(1):159-169.   Published online February 28, 2022
DOI: https://doi.org/10.3803/EnM.2021.1299
  • 5,059 View
  • 200 Download
  • 10 Web of Science
  • 12 Crossref
AbstractAbstract PDFSupplementary MaterialPubReader   ePub   
Background
We aim to validate the diagnostic performance of thyroid core needle biopsy (CNB) for diagnosing malignancy in clinical settings to align with the changes made in recently updated thyroid CNB guidelines.
Methods
We retrospectively analyzed 1,381 thyroid CNB and 2,223 fine needle aspiration (FNA) samples. The FNA and CNB slides were interpreted according to the Bethesda System for Reporting Thyroid Cytopathology and updated practice guidelines for thyroid CNB, respectively.
Results
Compared to FNA, CNB showed lower rates of inconclusive results: categories I (2.8% vs. 11.2%) and III (1.2% vs. 6.2%), and higher rates of categories II (60.9% vs. 50.4%) and IV (17.5% vs. 2.0%). The upper and lower bounds of the risk of malignancy (ROM) for category IV of CNB were 43.2% and 26.6%, respectively. The CNB subcategory IVb with nuclear atypia had a higher ROM than the subcategory without nuclear atypia (40%–62% vs. 23%–36%). In histologically confirmed cases, there was no significant difference in the diagnostic performance between CNB and FNA for malignancy. However, neoplastic diseases were more frequently detected by CNB than by FNA (88.8% vs. 77.6%, P=0.046). In category IV, there was no difference in unnecessary surgery rate between CNB and FNA (4.7% vs. 6.9%, P=0.6361).
Conclusion
Thyroid CNB decreased the rate of inconclusive results and showed a higher category IV diagnostic rate than FNA. The revised guidelines for thyroid CNB proved to be an excellent reporting system for assessing thyroid nodules.

Citations

Citations to this article as recorded by  
  • Examining the impact of several factors including COVID‐19 on thyroid fine‐needle aspiration biopsy
    Muzaffer Serdar Deniz, Merve Dindar
    Diagnostic Cytopathology.2024; 52(1): 42.     CrossRef
  • Consensus SFE-AFCE-SFMN 2022 sur la prise en charge des nodules thyroïdiens : intérêt et place de la cytologie thyroïdienne
    Myriam Decaussin-Petrucci, Beatrix Cochand Priollet, Emannuelle Leteurtre, Frédérique Albarel, Françoise Borson-Chazot
    Annales de Pathologie.2024; 44(1): 20.     CrossRef
  • A comparative analysis of core needle biopsy and repeat fine needle aspiration in patients with inconclusive initial cytology of thyroid nodules
    Xuejiao Su, Can Yue, Wanting Yang, Buyun Ma
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • The Diagnostic Role of Repeated Biopsy of Thyroid Nodules with Atypia of Undetermined Significance with Architectural Atypia on Core-Needle Biopsy
    Hye Hyeon Moon, Sae Rom Chung, Young Jun Choi, Tae-Yon Sung, Dong Eun Song, Tae Yong Kim, Jeong Hyun Lee, Jung Hwan Baek
    Endocrinology and Metabolism.2024; 39(2): 300.     CrossRef
  • Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules 2024
    Young Joo Park, Eun Kyung Lee, Young Shin Song, Su Hwan Kang, Bon Seok Koo, Sun Wook Kim, Dong Gyu Na, Seung-Kuk Baek, So Won Oh, Min Kyoung Lee, Sang-Woo Lee, Young Ah Lee, Yong Sang Lee, Ji Ye Lee, Dong-Jun Lim, Leehi Joo, Yuh-Seog Jung, Chan Kwon Jung,
    International Journal of Thyroidology.2024; 17(1): 208.     CrossRef
  • Korean Thyroid Association Guidelines on the Management of Differentiated Thyroid Cancers; Part I. Initial Management of Differentiated Thyroid Cancers - Chapter 2. Surgical Management of Thyroid Cancer 2024
    Yoon Young Cho, Cho Rok Lee, Ho-Cheol Kang, Bon Seok Koo, Hyungju Kwon, Sun Wook Kim, Won Woong Kim, Jung-Han Kim, Dong Gyu Na, Young Joo Park, Kyorim Back, Young Shin Song, Seung Hoon Woo, Ho-Ryun Won, Chang Hwan Ryu, Jee Hee Yoon, Min Kyoung Lee, Eun Ky
    International Journal of Thyroidology.2024; 17(1): 30.     CrossRef
  • Long-term efficacy of lobectomy for stage T1 papillary thyroid carcinoma with varying degrees of lymph node metastasis
    Chao Qin, Sijia Cai, Yanyu Qi, Meilin Liu, Weibo Xu, Min Yin, Haitao Tang, Qinghai Ji, Tian Liao, Yu Wang
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Current role of interventional radiology in thyroid nodules
    Onur Taydas, Erbil Arik, Omer Faruk Sevinc, Ahmet Burak Kara, Mustafa Ozdemir, Hasret Cengiz, Zulfu Bayhan, Mehmet Halil Ozturk
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Preoperative Risk Stratification of Follicular-patterned Thyroid Lesions on Core Needle Biopsy by Histologic Subtyping and RAS Variant-specific Immunohistochemistry
    Meejeong Kim, Sora Jeon, Chan Kwon Jung
    Endocrine Pathology.2023; 34(2): 247.     CrossRef
  • 2023 Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules
    Young Joo Park, Eun Kyung Lee, Young Shin Song, Soo Hwan Kang, Bon Seok Koo, Sun Wook Kim, Dong Gyu Na, Seung-Kuk Baek, So Won Oh, Min Kyoung Lee, Sang-Woo Lee, Young Ah Lee, Yong Sang Lee, Ji Ye Lee, Dong-Jun Lim, Leehi Joo, Yuh-Seog Jung, Chan Kwon Jung
    International Journal of Thyroidology.2023; 16(1): 1.     CrossRef
  • Reevaluating diagnostic categories and associated malignancy risks in thyroid core needle biopsy
    Chan Kwon Jung
    Journal of Pathology and Translational Medicine.2023; 57(4): 208.     CrossRef
  • A Matched-Pair Analysis of Nuclear Morphologic Features Between Core Needle Biopsy and Surgical Specimen in Thyroid Tumors Using a Deep Learning Model
    Faridul Haq, Andrey Bychkov, Chan Kwon Jung
    Endocrine Pathology.2022; 33(4): 472.     CrossRef
Close layer
Thyroid
Clinicopathological Characteristics and Recurrence-Free Survival of Rare Variants of Papillary Thyroid Carcinomas in Korea: A Retrospective Study
Mijin Kim, Sun Wook Cho, Young Joo Park, Hwa Young Ahn, Hee Sung Kim, Yong Joon Suh, Dughyun Choi, Bu Kyung Kim, Go Eun Yang, Il-Seok Park, Ka Hee Yi, Chan Kwon Jung, Bo Hyun Kim
Endocrinol Metab. 2021;36(3):619-627.   Published online June 10, 2021
DOI: https://doi.org/10.3803/EnM.2021.974
  • 5,518 View
  • 192 Download
  • 7 Web of Science
  • 6 Crossref
AbstractAbstract PDFPubReader   ePub   
Background
We aimed to evaluate the clinicopathological features and biological behaviors of Korean thyroid cancer patients with rare variants of papillary thyroid carcinoma (PTC) to address the ambiguity regarding the prognostic consequences of these variants.
Methods
We retrospectively reviewed the medical records of 5,496 patients who underwent thyroid surgery for PTC, between January and December 2012, in nine tertiary hospitals. Rare PTC variants included tall cell (TCV), columnar cell (CCV), diffuse sclerosing (DSV), cribriform-morular (CMV), solid (SV), hobnail, and Warthin-like variants. Recurrence-free survival (RFS) was defined as the time from the date of thyroidectomy until recurrence.
Results
Rare variants accounted for 1.1% (n=63) of the PTC patients; with 0.9% TCV, 0.02% CCV, 0.1% DSV, 0.1% CMV, and 0.1% SV. The mean age of patients and primary tumor size were 42.1±13.1 years and 1.3±0.9 cm, respectively. Extrathyroidal extension and cervical lymph node metastasis were observed in 38 (60.3%) and 37 (58.7%) patients, respectively. Ultrasonographic findings revealed typical malignant features in most cases. During a median follow-up of 7 years, 6.3% of patients experienced a locoregional recurrence. The 5-year RFS rates were 71.4% in patients with DSV or SV, 95.9% for TCV, or CCV, and 100% for other variants. DSV emerged an independent risk factor associated with shorter RFS.
Conclusion
In this multicenter Korean cohort, rare variants accounted for 1.1% of all PTC cases, with TCV being the most frequent subtype. DSV emerged as a significant prognostic factor for RFS.

Citations

Citations to this article as recorded by  
  • Nomogram predicts cervical lymph node metastasis of pathological subtypes of papillary thyroid carcinoma
    Ziyu Luo, Wenhan Li, Binliang Huo, Jianhui Li
    Langenbeck's Archives of Surgery.2024;[Epub]     CrossRef
  • Serum thyroglobulin testing after thyroid lobectomy in patients with 1–4 cm papillary thyroid carcinoma
    Ahreum Jang, Meihua Jin, Chae A Kim, Min Ji Jeon, Yu-Mi Lee, Tae-Yon Sung, Tae Yong Kim, Won Bae Kim, Young Kee Shong, Won Gu Kim
    Endocrine.2023; 81(2): 290.     CrossRef
  • Do Histologically Aggressive Subtypes of Papillary Thyroid Microcarcinoma have Worse Clinical Outcome than Non-Aggressive Papillary Thyroid Microcarcinoma Subtypes? A Multicenter Cohort Study
    Sayid Shafi Zuhur, Hunkar Aggul, Ugur Avci, Selvinaz Erol, Mazhar Müslüm Tuna, Serhat Uysal, Gulhan Akbaba, Faruk Kilinç, Merve Catak, Sakin Tekin, Ogun Irem Bilen, Beyza Olcay Öztürk, Ecem Bilgehan Erden, Gulsah Elbuken, Halise Cinar Yavuz, Pinar Kadiogl
    Hormone and Metabolic Research.2023; 55(05): 323.     CrossRef
  • The Warthin-like variant of papillary thyroid carcinomas: a clinicopathologic analysis report of two cases
    Xing Zhao, Yijia Zhang, Pengyu Hao, Mingzhen Zhao, Xingbin Shen
    Oncologie.2023; 25(5): 581.     CrossRef
  • A Retrospective Cohort Study with Validation of Predictors of Differentiated Thyroid Cancer Outcomes
    Ayanthi Wijewardene, Anthony J. Gill, Matti Gild, Diana L. Learoyd, Anthony Robert Glover, Mark Sywak, Stan Sidhu, Paul Roach, Geoffrey Schembri, Jeremy Hoang, Bruce Robinson, Lyndal Tacon, Roderick Clifton-Bligh
    Thyroid.2022;[Epub]     CrossRef
  • Clinicopathological Implications of the BRAFV600E Mutation in Papillary Thyroid Carcinoma of Ukrainian Patients Exposed to the Chernobyl Radiation in Childhood: A Study for 30 Years After the Accident
    Liudmyla Zurnadzhy, Tetiana Bogdanova, Tatiana I. Rogounovitch, Masahiro Ito, Mykola Tronko, Shunichi Yamashita, Norisato Mitsutake, Michael Bolgov, Serhii Chernyshov, Sergii Masiuk, Vladimir A. Saenko
    Frontiers in Medicine.2022;[Epub]     CrossRef
Close layer
Adrenal gland
Diagnosis for Pheochromocytoma and Paraganglioma: A Joint Position Statement of the Korean Pheochromocytoma and Paraganglioma Task Force
Eu Jeong Ku, Kyoung Jin Kim, Jung Hee Kim, Mi Kyung Kim, Chang Ho Ahn, Kyung Ae Lee, Seung Hun Lee, You-Bin Lee, Kyeong Hye Park, Yun Mi Choi, Namki Hong, A Ram Hong, Sang-Wook Kang, Byung Kwan Park, Moon-Woo Seong, Myungshin Kim, Kyeong Cheon Jung, Chan Kwon Jung, Young Seok Cho, Jin Chul Paeng, Jae Hyeon Kim, Ohk-Hyun Ryu, Yumie Rhee, Chong Hwa Kim, Eun Jig Lee
Endocrinol Metab. 2021;36(2):322-338.   Published online April 6, 2021
DOI: https://doi.org/10.3803/EnM.2020.908
  • 9,334 View
  • 670 Download
  • 10 Web of Science
  • 15 Crossref
AbstractAbstract PDFPubReader   ePub   
Pheochromocytoma and paraganglioma (PPGLs) are rare catecholamine-secreting neuroendocrine tumors but can be life-threatening. Although most PPGLs are benign, approximately 10% have metastatic potential. Approximately 40% cases are reported as harboring germline mutations. Therefore, timely and accurate diagnosis of PPGLs is crucial. For more than 130 years, clinical, molecular, biochemical, radiological, and pathological investigations have been rapidly advanced in the field of PPGLs. However, performing diagnostic studies to localize lesions and detect metastatic potential can be still challenging and complicated. Furthermore, great progress on genetics has shifted the paradigm of genetic testing of PPGLs. The Korean PPGL task force team consisting of the Korean Endocrine Society, the Korean Surgical Society, the Korean Society of Nuclear Medicine, the Korean Society of Pathologists, and the Korean Society of Laboratory Medicine has developed this position statement focusing on the comprehensive and updated diagnosis for PPGLs.

Citations

Citations to this article as recorded by  
  • A Prospective Comparative Study of 18F-FDOPA PET/CT Versus 123I-MIBG Scintigraphy With SPECT/CT for the Diagnosis of Pheochromocytoma and Paraganglioma
    Changhwan Sung, Hyo Sang Lee, Dong Yun Lee, Yong-il Kim, Jae Eun Kim, Sang Ju Lee, Seung Jun Oh, Tae-Yon Sung, Yu-Mi Lee, Young Hoon Kim, Beom-Jun Kim, Jung-Min Koh, Seung Hun Lee, Jin-Sook Ryu
    Clinical Nuclear Medicine.2024; 49(1): 27.     CrossRef
  • Preoperative prediction of metastatic pheochromocytoma and paraganglioma using clinical, genetic, and biochemical markers: A cohort study
    Seung Shin Park, Chang Ho Ahn, Seunghoo Lee, Woochang Lee, Won Woong Kim, Yu‐Mi Lee, Su Jin Kim, Tae‐Yon Sung, Kyu Eun Lee, Jung Hee Kim, Seung Hun Lee, Jung‐Min Koh
    Journal of Internal Medicine.2024; 296(1): 68.     CrossRef
  • Germline Mutations and Phenotypic Associations in Korean Patients With Pheochromocytoma and Paraganglioma: A Multicenter Study and Literature Review
    Kwan Hoon Jo, Jaewoong Lee, Jaeeun Yoo, Hoon Seok Kim, Eun Sook Kim, Je Ho Han, Yi Sun Jang, Jae-Seung Yun, Jang Won Son, Soon Jib Yoo, Seung Hwan Lee, Dong Jun Lim, Hyuk-Sang Kwon, Seungok Lee, Sungdae Moon, Myungshin Kim
    Annals of Laboratory Medicine.2024; 44(6): 591.     CrossRef
  • Raccomandazioni della lista del GdS-Endocrinologia e Malattie del Metabolismo SIPMeL-Choosing wisely: tiroide, anticorpi anti-tiroide, cortisolo, surrene, vitamina D: aggiornamento 2024
    Romolo M. DORIZZI, Vincenzo BRESCIA, Marina VITILLO, Ottavia PORZIO, Federica D’AURIZIO
    La Rivista Italiana della Medicina di Laboratorio.2024;[Epub]     CrossRef
  • Screening and treatment of endocrine hypertension focusing on adrenal gland disorders: a narrative review
    Seung Min Chung
    Journal of Yeungnam Medical Science.2024; 41(4): 269.     CrossRef
  • Clinical and epidemiological characteristics of patients with pheochromocytoma and retroperitoneal paraganglioma
    D. V. Rebrova, N. V. Vorokhobina
    Meditsinskiy sovet = Medical Council.2024; (16): 206.     CrossRef
  • Evaluation and Management of Bone Health in Patients with Thyroid Diseases: A Position Statement of the Korean Thyroid Association
    A Ram Hong, Ho-Cheol Kang
    Endocrinology and Metabolism.2023; 38(2): 175.     CrossRef
  • Lesion-based indicators predict long-term outcomes of pheochromocytoma and paraganglioma– SIZEPASS
    Helena Hanschell, Salvador Diaz-Cano, Alfredo Blanes, Nadia Talat, Gabriele Galatá, Simon Aylwin, Klaus Martin Schulte
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Interleukin-6-producing paraganglioma as a rare cause of systemic inflammatory response syndrome: a case report
    Yin Young Lee, Seung Min Chung
    Journal of Yeungnam Medical Science.2023; 40(4): 435.     CrossRef
  • (Extremely rare intrapericardial location of paraganglioma)
    Jaroslav Zajíc, Aleš Mokráček, Ladislav Pešl, Jiří Haniš, Dita Schaffelhoferová
    Cor et Vasa.2023; 65(4): 692.     CrossRef
  • A Case of Von Hippel-Lindau Disease With Recurrence of Paraganglioma and No Other Associated Symptoms: The Importance of Genetic Testing and Establishing Follow-Up Policies
    Naoki Okada, Akihiro Shioya, Sumihito Togi, Hiroki Ura, Yo Niida
    Cureus.2023;[Epub]     CrossRef
  • KSNM60 in Nuclear Endocrinology: from the Beginning to the Future
    Chae Moon Hong, Young Jin Jeong, Hae Won Kim, Byeong-Cheol Ahn
    Nuclear Medicine and Molecular Imaging.2022; 56(1): 17.     CrossRef
  • Change of Computed Tomography-Based Body Composition after Adrenalectomy in Patients with Pheochromocytoma
    Yousun Ko, Heeryoel Jeong, Seungwoo Khang, Jeongjin Lee, Kyung Won Kim, Beom-Jun Kim
    Cancers.2022; 14(8): 1967.     CrossRef
  • Evaluation and Management of Bone Health in Patients with Thyroid Diseases: a Position Statement from the Korean Thyroid Association
    A Ram Hong, Hwa Young Ahn, Bu Kyung Kim, Seong Hee Ahn, So Young Park, Min-Hee Kim, Jeongmin Lee, Sun Wook Cho, Ho-Cheol Kang
    International Journal of Thyroidology.2022; 15(1): 1.     CrossRef
  • Pheochromocytoma with Retroperitoneal Metastasis: A Case Report
    建新 崔
    Advances in Clinical Medicine.2021; 11(05): 2239.     CrossRef
Close layer
Clinical Study
Molecular Correlates and Nuclear Features of Encapsulated Follicular-Patterned Thyroid Neoplasms
Chan Kwon Jung, Andrey Bychkov, Dong Eun Song, Jang-Hee Kim, Yun Zhu, Zhiyan Liu, Somboon Keelawat, Chiung-Ru Lai, Mitsuyoshi Hirokawa, Kaori Kameyama, Kennichi Kakudo
Endocrinol Metab. 2021;36(1):123-133.   Published online February 24, 2021
DOI: https://doi.org/10.3803/EnM.2020.860
  • 6,210 View
  • 168 Download
  • 12 Web of Science
  • 12 Crossref
AbstractAbstract PDFPubReader   ePub   
Background
Assessing nuclear features is diagnostically challenging in the aspect of thyroid pathology. The aim of this study was to determine whether pathologists could distinguish BRAF-like and RAS-like nuclear features morphologically and identify morphological features to differentiate thyroid tumors with RAS-like mutations from encapsulated papillary thyroid carcinoma (PTC) with predominant follicular growth and BRAFV600E mutation.
Methods
Representative whole slide images of 16 encapsulated thyroid tumors with predominant follicular growth were reviewed by 12 thyroid pathologists using a web browser-based image viewer. Total nuclear score was calculated from semi-quantitatively scored eight nuclear features. The molecular profile of RAS and BRAF genes was determined by Sanger sequencing.
Results
Total nuclear score ranging 0 to 24 could differentiate BRAF-like tumors from RAS-like tumors with a cut-off value of score 14. The interobserver agreement was the highest for the assessment of nuclear pseudoinclusions (NPIs) but the lowest for nuclear elongation and sickle-shaped nuclei. NPIs were found in tumors with BRAFV600E mutation, but not in tumors with RAS-like mutations. Total nuclear scores were significantly higher for tumors with BRAFV600E than for those with RAS-like mutations (P<0.001).
Conclusion
Our results suggest that NPIs and high nuclear scores have diagnostic utility as rule-in markers for differentiating PTC with BRAFV600E mutation from benign or borderline follicular tumors with RAS-like mutations. Relaxation of rigid criteria for nuclear features resulted in an overdiagnosis of PTC. Immunostaining or molecular testing for BRAFV600E mutation is a useful adjunct for cases with high nuclear scores to identify true PTC.

Citations

Citations to this article as recorded by  
  • Differentiating BRAF V600E- and RAS-like alterations in encapsulated follicular patterned tumors through histologic features: a validation study
    Chankyung Kim, Shipra Agarwal, Andrey Bychkov, Jen-Fan Hang, Agnes Stephanie Harahap, Mitsuyoshi Hirokawa, Kennichi Kakudo, Somboon Keelawat, Chih-Yi Liu, Zhiyan Liu, Truong Phan-Xuan Nguyen, Chanchal Rana, Huy Gia Vuong, Yun Zhu, Chan Kwon Jung
    Virchows Archiv.2024; 484(4): 645.     CrossRef
  • Clinicopathologic Features and Cytologic Correlation of ALK-Rearranged Papillary Thyroid Carcinoma: A Series of Eight Cases
    Kun-Ping Shih, Yu-Cheng Lee, Jia-Jiun Tsai, Shu-Hui Lin, Chih-Yi Liu, Wan-Shan Li, Chien-Feng Li, Jen-Fan Hang
    Endocrine Pathology.2024; 35(2): 134.     CrossRef
  • Small Multi-Gene DNA Panel Can Aid in Reducing the Surgical Resection Rate and Predicting the Malignancy Risk of Thyroid Nodules
    Moon Young Oh, Hye-Mi Choi, Jinsun Jang, Heejun Son, Seung Shin Park, Minchul Song, Yoo Hyung Kim, Sun Wook Cho, Young Jun Chai, Woosung Chung, Young Joo Park
    Endocrinology and Metabolism.2024; 39(5): 777.     CrossRef
  • The Presence of Typical “BRAFV600E-Like” Atypia in Papillary Thyroid Carcinoma is Highly Specific for the Presence of the BRAFV600E Mutation
    John Turchini, Loretta Sioson, Adele Clarkson, Amy Sheen, Leigh Delbridge, Anthony Glover, Mark Sywak, Stan Sidhu, Anthony J. Gill
    Endocrine Pathology.2023; 34(1): 112.     CrossRef
  • Could Oxidative Stress Play a Role in the Development and Clinical Management of Differentiated Thyroid Cancer?
    Maria Kościuszko, Angelika Buczyńska, Adam Jacek Krętowski, Anna Popławska-Kita
    Cancers.2023; 15(12): 3182.     CrossRef
  • Pitfalls in thyroid pathology and the medicolegal aspects of error
    David N Poller
    Diagnostic Histopathology.2023; 29(11): 495.     CrossRef
  • Developing Models to Predict BRAFV600E and RAS Mutational Status in Papillary Thyroid Carcinoma Using Clinicopathological Features and pERK1/2 Immunohistochemistry Expression
    Agnes Stephanie Harahap, Imam Subekti, Sonar Soni Panigoro, Asmarinah, Lisnawati, Retno Asti Werdhani, Hasrayati Agustina, Dina Khoirunnisa, Mutiah Mutmainnah, Fajar Lamhot Gultom, Abdillah Hasbi Assadyk, Maria Francisca Ham
    Biomedicines.2023; 11(10): 2803.     CrossRef
  • The Asian Thyroid Working Group, from 2017 to 2023
    Kennichi Kakudo, Chan Kwon Jung, Zhiyan Liu, Mitsuyoshi Hirokawa, Andrey Bychkov, Huy Gia Vuong, Somboon Keelawat, Radhika Srinivasan, Jen-Fan Hang, Chiung-Ru Lai
    Journal of Pathology and Translational Medicine.2023; 57(6): 289.     CrossRef
  • Noninvasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP): Tumour Entity with a Short History. A Review on Challenges in Our Microscopes, Molecular and Ultrasonographic Profile
    Ivana Kholová, Elina Haaga, Jaroslav Ludvik, David Kalfert, Marie Ludvikova
    Diagnostics.2022; 12(2): 250.     CrossRef
  • Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach
    Chan Kwon Jung, Andrey Bychkov, Kennichi Kakudo
    Endocrinology and Metabolism.2022; 37(5): 703.     CrossRef
  • Different Threshold of Malignancy for RAS-like Thyroid Tumors Causes Significant Differences in Thyroid Nodule Practice
    Kennichi Kakudo
    Cancers.2022; 14(3): 812.     CrossRef
  • The Incidence of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: A Meta-Analysis Assessing Worldwide Impact of the Reclassification
    Chanchal Rana, Huy Gia Vuong, Thu Quynh Nguyen, Hoang Cong Nguyen, Chan Kwon Jung, Kennichi Kakudo, Andrey Bychkov
    Thyroid.2021;[Epub]     CrossRef
Close layer
Thyroid
Updates in the Pathologic Classification of Thyroid Neoplasms: A Review of the World Health Organization Classification
Yanhua Bai, Kennichi Kakudo, Chan Kwon Jung
Endocrinol Metab. 2020;35(4):696-715.   Published online December 2, 2020
DOI: https://doi.org/10.3803/EnM.2020.807
  • 18,463 View
  • 1,351 Download
  • 45 Web of Science
  • 47 Crossref
AbstractAbstract PDFPubReader   ePub   
Advances in medical sciences and evidence-based medicine have led to momentous changes in classification and management of thyroid neoplasms. Much progress has been made toward avoiding overdiagnosis and overtreatment of thyroid cancers. The new 2017 World Health Organization (WHO) classification of thyroid neoplasms updated the diagnostic criteria and molecular and genetic characteristics reflecting the biology and behavior of the tumors, and newly introduced the category of borderline malignancy or uncertain malignant potential. Some neoplasms were subclassified, renamed, or redefined as a specific entity. This review introduces changes in the fourth edition WHO classification of thyroid tumors and updates the contemporary diagnosis and classification of thyroid tumors. We also discuss several challenges with the proposal of new diagnostic entities, since they have unique histopathologic and molecular features and clinical relevance.

Citations

Citations to this article as recorded by  
  • Canine thyroid carcinomas: A review with emphasis on comparing the compact subtype of follicular thyroid carcinomas and medullary thyroid carcinomas
    Jillian M. Athey, Miranda D. Vieson, Keith Bailey, Dan Rudmann, Wes A. Baumgartner, Kim A. Selting
    Veterinary Pathology.2024; 61(1): 7.     CrossRef
  • Accuracy and diagnostic performance of the Bethesda system for reporting thyroid cytopathology in a tertiary endocrine surgical referral center in Belgium
    Sam Kinet, Hendrik Cornette, Klaas Van Den Heede, Nele Brusselaers, Sam Van Slycke
    World Journal of Surgery.2024; 48(2): 386.     CrossRef
  • Retrospective study of BRAFV600E mutation and CT features of papillary thyroid carcinoma
    Xiaoquan Hong, Juxiang Li, Shaoyin Duan, Youkuang You
    PeerJ.2024; 12: e16810.     CrossRef
  • “Examining the link between tooth agenesis and papillary thyroid cancer: is there a risk factor?” Observational study
    Željana Matošić, Luka Šimunović, Tomislav Jukić, Roko Granić, Senka Meštrović
    Progress in Orthodontics.2024;[Epub]     CrossRef
  • Research Progress of Tg and TgAb in Lymph Node Metastasis of Papillary Thyroid Carcinoma
    月 高
    Advances in Clinical Medicine.2024; 14(03): 499.     CrossRef
  • A patient with a rare co‐occurrence of papillary and follicular thyroid carcinomas
    Vijayvardhan Kamalumpundi, Erin Meyers, Maisoon Torfah, Marcelo Lima de Gusmão Correia
    Clinical Case Reports.2024;[Epub]     CrossRef
  • Coexistence of intrathyroid thymic carcinoma and papillary thyroid carcinoma: a case report and literature review
    Maryam Vajihinejad, Ali Ataei, Mohammad Pashmchi, Ali Aledavoud, Vahid Zand, Mohammad Ali Broomand, Mohammad Mohammadi, Niloofar Zare Reshkuiyeh
    Frontiers in Oncology.2024;[Epub]     CrossRef
  • Korean Thyroid Association Guidelines on the Management of Differentiated Thyroid Cancers; Part I. Initial Management of Differentiated Thyroid Cancers - Chapter 4. Pathological Diagnosis and Staging after Thyroidectomy 2024
    Su-Jin Shin, Hee Young Na, Ho-Cheol Kang, Sun Wook Kim, Dong Gyu Na, Young Joo Park, Young Shin Song, Eun Kyung Lee, Dong-Jun Lim, Yun Jae Chung, Chan Kwon Jung
    International Journal of Thyroidology.2024; 17(1): 61.     CrossRef
  • Clinical–Pathological Features of Thyroid Neoplasms in Young Patients Diagnosed in a Single Center
    Aura Jurescu, Dan Brebu, Alexandra Corina Faur, Octavia Vita, Robert Barna, Adrian Vaduva, Oana Popa, Anca Muresan, Mihaela Iacob, Marioara Cornianu, Remus Cornea
    Life.2024; 14(6): 696.     CrossRef
  • Clinical, Pathological, and Immunohistochemical Predictors of Cause-Specific Mortality in Papillary Thyroid Cancer: Multivariate Analysis
    M. A. Bakarev, A. A. Ivanov, E. L. Lushnikova
    Bulletin of Experimental Biology and Medicine.2024; 177(3): 353.     CrossRef
  • Molecular Markers in Follicular and Oncocytic Thyroid Carcinomas: Clinical Application of Molecular Genetic Testing
    Alicia Belaiche, Grégoire B. Morand, Sena Turkdogan, Esther ShinHyun Kang, Véronique-Isabelle Forest, Marc P. Pusztaszeri, Michael P. Hier, Alex M. Mlynarek, Keith Richardson, Nader Sadeghi, Marco A. Mascarella, Sabrina D. Da Silva, Richard J. Payne
    Current Oncology.2024; 31(10): 5919.     CrossRef
  • Genetic analysis and clinicopathologic features of locally advanced papillary thyroid cancers: a prospective observational study
    Zheng Ding, Xuanbin Tao, Xianzhao Deng, Bomin Guo, Jie Kang, Bo Wu, Zhili Yang, Chunyan Chen, Ping Liu, Yingchao Zhang, Youben Fan, Zhiyan Liu
    Journal of Cancer Research and Clinical Oncology.2023; 149(9): 6303.     CrossRef
  • Intrathyroid thymic carcinoma: clinicopathological features and whole exome sequencing analysis
    Jiayu Li, Run Xiang, Yunzhu Li, Qiong Liao, Yang Liu
    Virchows Archiv.2023; 482(5): 813.     CrossRef
  • Lenvatinib as a Promising Treatment Option for Unresectable Hürthle Cell Carcinoma: A Case Report
    Parth S Shirode, Anil D'cruz, Sataksi Chatterjee, Swayambhu Bhandarkar
    Cureus.2023;[Epub]     CrossRef
  • Histological Variants of Papillary Thyroid Cancer in Relation to Clinical and Morphological Parameters and Prognosis
    A. A. Ivanov, M. A. Bakarev, E. L. Lushnikova
    Bulletin of Experimental Biology and Medicine.2023; 174(5): 647.     CrossRef
  • Molecular profile of follicular tumors of the thyroid gland
    D. D. Dolidze, A. V. Shabunin, S. D. Сovantsev, Z. A. Bagateliya, Yu. N. Kobzev, D. L. Rotin, K. A. Mulaeva, M. V. Kovaleva
    Head and Neck Tumors (HNT).2023; 13(1): 102.     CrossRef
  • The predictive models based on multimodality ultrasonography for the differential diagnosis of thyroid nodules smaller than 10 mm
    Gang Li, Sai Ma, Fan Zhang, Chao Jia, Long Liu, Feng Gao, Qiusheng Shi, Rong Wu, Lianfang Du, Fan Li
    The British Journal of Radiology.2023;[Epub]     CrossRef
  • The Warthin-like variant of papillary thyroid carcinomas: a clinicopathologic analysis report of two cases
    Xing Zhao, Yijia Zhang, Pengyu Hao, Mingzhen Zhao, Xingbin Shen
    Oncologie.2023; 25(5): 581.     CrossRef
  • Giant Anaplastic Thyroid Carcinoma of Sarcomatoid Type with Obstructive Symptoms: A Case Report
    Gustavo D Saenz-Poma, Shirley N Cisneros-Chumacero, Juan D Millan-Landeo, Nayra Quispe-Yauri, Alba S Zevallos
    World Journal of Endocrine Surgery.2023; 15(1): 18.     CrossRef
  • Differentiating Benign from Malignant Thyroid Tumors by Kinase Activity Profiling and Dabrafenib BRAF V600E Targeting
    Riet Hilhorst, Adrienne van den Berg, Piet Boender, Tom van Wezel, Tim Kievits, Rik de Wijn, Rob Ruijtenbeek, Willem E. Corver, Hans Morreau
    Cancers.2023; 15(18): 4477.     CrossRef
  • Agrin is a novel oncogenic protein in thyroid cancer
    Anna Adamiok‑Ostrowska, Małgorzata Grzanka, Barbara Czarnocka
    Oncology Letters.2023;[Epub]     CrossRef
  • Investigation of pre‐operative demographic, biochemical, sonographic and cytopathological findings in low‐risk thyroid neoplasms
    Muzaffer Serdar Deniz, Didem Özdemir, Narin Nasıroğlu İmga, Hüsniye Başer, Fatma Neslihan Çuhacı Seyrek, Ayşegül Aksoy Altınboğa, Oya Topaloğlu, Reyhan Ersoy, Bekir Çakır
    Clinical Endocrinology.2023; 99(5): 502.     CrossRef
  • The Asian Thyroid Working Group, from 2017 to 2023
    Kennichi Kakudo, Chan Kwon Jung, Zhiyan Liu, Mitsuyoshi Hirokawa, Andrey Bychkov, Huy Gia Vuong, Somboon Keelawat, Radhika Srinivasan, Jen-Fan Hang, Chiung-Ru Lai
    Journal of Pathology and Translational Medicine.2023; 57(6): 289.     CrossRef
  • Drug-induced inhibition of HMGA and EZH2 activity as a possible therapy for anaplastic thyroid carcinoma
    Marco De Martino, Simona Pellecchia, Myriam Decaussin-Petrucci, Domenico Testa, Nathalia Meireles Da Costa, Pierlorenzo Pallante, Paolo Chieffi, Alfredo Fusco, Francesco Esposito
    Cell Cycle.2023; 22(23-24): 2552.     CrossRef
  • RESULTS OF A MORPHOLOGICAL STUDY OF THE THYROID GLAND IN PATIENTS WITH AUTOIMMUNE THYROIDITIS
    F. G. Sadikhov
    World of Medicine and Biology.2023; 19(86): 137.     CrossRef
  • Anaplastik Tiroid Karsinomu Tanısında Morfolojik ve İmmünohistokimyasal Bulguların Yeri: 10 Yıllık Seri
    Özlem SARAYDAROĞLU, Rabia DÖLEK, Özen ÖZ GÜL, Ercüment GÜRLÜLER
    Uludağ Üniversitesi Tıp Fakültesi Dergisi.2023; 49(3): 411.     CrossRef
  • The Efficacy of ACR TI-RADS in the Management of Suspected Thyroid Nodules and Its Correlation With the Bethesda Scoring System
    Emrah Karatay, Mirkhalig Javadov, Kinyas Kartal
    Journal of Diagnostic Medical Sonography.2022; 38(4): 309.     CrossRef
  • Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro
    Kun Yu, Zhuo Tan, Ying Xin
    Molecular Biology Reports.2022; 49(4): 2785.     CrossRef
  • Clinical Significance of Circulating Tumor Cells (CTCs) and Survivin on Predicting Prognosis in Thyroid Cancer Patients
    Xun Weng, YangYang, Yujiao Cai, Fu Wang
    Disease Markers.2022; 2022: 1.     CrossRef
  • Identification of DPP4/CTNNB1/MET as a Theranostic Signature of Thyroid Cancer and Evaluation of the Therapeutic Potential of Sitagliptin
    Sheng-Yao Cheng, Alexander T. H. Wu, Gaber El-Saber Batiha, Ching-Liang Ho, Jih-Chin Lee, Halimat Yusuf Lukman, Mohammed Alorabi, Abdullah N. AlRasheedi, Jia-Hong Chen
    Biology.2022; 11(2): 324.     CrossRef
  • Retrospective evaluation of radioactive iodine ablation therapy in the Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) and Thyroid tumors with uncertain malignity potential
    Mehmet Refik GÖKTUĞ, Özen ÖZ GÜL, Soner CANDER
    Turkish Journal of Internal Medicine.2022; 4: 88.     CrossRef
  • Extracellular Vesicles as Signal Carriers in Malignant Thyroid Tumors?
    Małgorzata Grzanka, Anna Stachurska-Skrodzka, Anna Adamiok-Ostrowska, Ewa Gajda, Barbara Czarnocka
    International Journal of Molecular Sciences.2022; 23(6): 3262.     CrossRef
  • Thyroid Cancer Detection in a Routine Clinical Setting: Performance of ACR TI-RADS, FNAC, and Molecular Testing in Prospective Cohort Study
    Tereza Grimmichova, Petra Pacesova, Martin Hill, Barbora Pekova, Marketa Vankova, Jitka Moravcova, Jana Vrbikova, Zdenek Novak, Karolina Mastnikova, Eliska Vaclavikova, Josef Vcelak, Bela Bendlova, Jana Drozenova, Vlasta Sykorova
    Biomedicines.2022; 10(5): 954.     CrossRef
  • Advantages of Small Incision Surgery in Thyroid Tumors
    Wen Feng, Yuan Feng, Qixian Diao, Jian Zhou, Zhaoqi Dong
    Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1.     CrossRef
  • Radioactive Iodine Therapy Does not Improve Cancer-specific Survival in Hürthle Cell Carcinoma of the Thyroid
    Xiaofei Wang, Xun Zheng, Jingqiang Zhu, Zhihui Li, Tao Wei
    The Journal of Clinical Endocrinology & Metabolism.2022; 107(11): 3144.     CrossRef
  • Latency Trend Analysis as a Guide to Screening Malignancy Survivors for Second Primary Thyroid Cancer
    Mohammad Hussein, Lauren Mueller, Peter P. Issa, Muhib Haidari, Lily Trinh, Eman Toraih, Emad Kandil
    Biomedicines.2022; 10(8): 1984.     CrossRef
  • Ultrasonographic characteristics of Hürthle cell neoplasms: prediction of malignancy
    Min Je Kim, Jung Hee Shin, Soo Yeon Hahn, Young Lyun Oh, Sun Wook Kim, Tae Hyuk Kim, Yaeji Lim, Sanghyuk Lee
    Ultrasonography.2022; 41(4): 689.     CrossRef
  • Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach
    Chan Kwon Jung, Andrey Bychkov, Kennichi Kakudo
    Endocrinology and Metabolism.2022; 37(5): 703.     CrossRef
  • A Matched-Pair Analysis of Nuclear Morphologic Features Between Core Needle Biopsy and Surgical Specimen in Thyroid Tumors Using a Deep Learning Model
    Faridul Haq, Andrey Bychkov, Chan Kwon Jung
    Endocrine Pathology.2022; 33(4): 472.     CrossRef
  • Clinicopathological features and prognostic factors analysis of multiple synchronous distinct subtypes of primary thyroid carcinoma
    Quanwei Dai, Xinghao Fu, Yalei Ding, Qi He, Xinguang Qiu
    Endocrine.2022; 79(3): 491.     CrossRef
  • Prevalence of Thyroid Lesions in Thyroidectomy Specimens - A Histomorphological Study in Urban Industrial Area
    Shirish Sahebrao Chandanwale, Diva Sutreja, Payal Patel, Anubhaw Verma, Sushma Kulkarni
    Journal of Head & Neck Physicians and Surgeons.2022; 10(1): 80.     CrossRef
  • Best Achievements in Clinical Thyroidology in 2020
    Eun Kyung Lee, Young Joo Park
    Endocrinology and Metabolism.2021; 36(1): 30.     CrossRef
  • High Prevalence of DICER1 Mutations and Low Frequency of Gene Fusions in Pediatric Follicular-Patterned Tumors of the Thyroid
    Ja-Seong Bae, Seung-Hyun Jung, Mitsuyoshi Hirokawa, Andrey Bychkov, Akira Miyauchi, Sohee Lee, Yeun-Jun Chung, Chan Kwon Jung
    Endocrine Pathology.2021; 32(3): 336.     CrossRef
  • Deep Learning Fast Screening Approach on Cytological Whole Slides for Thyroid Cancer Diagnosis
    Yi-Jia Lin, Tai-Kuang Chao, Muhammad-Adil Khalil, Yu-Ching Lee, Ding-Zhi Hong, Jia-Jhen Wu, Ching-Wei Wang
    Cancers.2021; 13(15): 3891.     CrossRef
  • How to identify indolent thyroid tumors unlikely to recur and cause cancer death immediately after surgery—Risk stratification of papillary thyroid carcinoma in young patients—
    Kennichi Kakudo, Zhiyan Liu, Yanhua Bai, Yaqiong Li, Naomi Kitayama, Shinya Satoh, Masahiro Nakashima, Chan Kwon Jung
    Endocrine Journal.2021; 68(8): 871.     CrossRef
  • Papillary Thyroid Cancer Prognosis: An Evolving Field
    Salvatore Ulisse, Enke Baldini, Augusto Lauro, Daniele Pironi, Domenico Tripodi, Eleonora Lori, Iulia Catalina Ferent, Maria Ida Amabile, Antonio Catania, Filippo Maria Di Matteo, Flavio Forte, Alberto Santoro, Piergaspare Palumbo, Vito D’Andrea, Salvator
    Cancers.2021; 13(21): 5567.     CrossRef
  • Intrasalivary Thymic Carcinoma: A Case Report and Literature Review
    Michał Kunc, Alexandra Kamieniecki, Grzegorz Walczak, Tomasz Nowicki, Bartosz Wasąg, Bogusław Mikaszewski, Dominik Stodulski, Wojciech Biernat
    Head and Neck Pathology.2021; 16(3): 857.     CrossRef
Close layer
Recent Advances in Core Needle Biopsy for Thyroid Nodules
Chan Kwon Jung, Jung Hwan Baek
Endocrinol Metab. 2017;32(4):407-412.   Published online December 14, 2017
DOI: https://doi.org/10.3803/EnM.2017.32.4.407
  • 6,576 View
  • 90 Download
  • 29 Web of Science
  • 27 Crossref
AbstractAbstract PDFPubReader   

Core needle biopsy (CNB) was introduced as an alternative diagnostic tool to fine-needle aspiration (FNA), and is increasingly being used in the preoperative assessment of thyroid nodules. CNB provides a definitive diagnosis in most cases, but it sometimes may be inconclusive. CNB has the advantage of enabling a histologic examination in relation to the surrounding thyroid tissue, immunohistochemistry, and molecular testing that can provide a more accurate assessment than FNA in selected cases. Nevertheless, CNB should be performed only by experienced experts in thyroid interventions to prevent complications because CNB needles are larger in caliber than FNA needles. As recent evidence has accumulated, and with improvements in the technique and devices for thyroid CNB, the Korean Society of Thyroid Radiology released its 2016 thyroid CNB guidelines and the Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group published a consensus statement on the pathology reporting system for thyroid CNB in 2015. This review presents the current consensus and recommendations regarding thyroid CNB, focusing on indications, complications, and pathologic classification and reporting.

Citations

Citations to this article as recorded by  
  • Diagnosing and management of thyroid nodules and goiter – current perspectives
    Katica Bajuk Studen, Bartosz Domagała, Simona Gaberšček, Katja Zaletel, Alicja Hubalewska-Dydejczyk
    Endocrine.2024;[Epub]     CrossRef
  • Parenchymal microcalcifications in the thyroid gland: Clinical significance and management strategy
    Younghee Yim, Hye Sun Park, Jung Hwan Baek, Hyunju Yoo, Jin Yong Sung
    Medicine.2023; 102(32): e34636.     CrossRef
  • Strategies for Safe and Effective Core Needle Biopsy of Thyroid Nodules with Macrocalcification
    Jae Ho Shin
    International Journal of Thyroidology.2023; 16(2): 195.     CrossRef
  • Utilidad de la biopsia con aguja gruesa ecoguiada en nódulos tiroideos con punción aspirativa con aguja fina no diagnóstica
    R. Cortázar-García, M.D. Martín-Escalante, L. Robles-Cabeza, C. Martínez-Santos
    Radiología.2022; 64(3): 195.     CrossRef
  • Usefulness of ultrasound-guided core biopsy in thyroid nodules with inconclusive fine-needle aspiration biopsy findings
    R. Cortázar-García, M.D. Martín-Escalante, L. Robles-Cabeza, C. Martínez-Santos
    Radiología (English Edition).2022; 64(3): 195.     CrossRef
  • Effectiveness of core needle biopsy in the diagnosis of thyroid lymphoma and anaplastic thyroid carcinoma: A systematic review and meta-analysis
    Vincent Vander Poorten, Nathan Goedseels, Asterios Triantafyllou, Alvaro Sanabria, Paul M. Clement, Oded Cohen, Pawel Golusinski, Orlando Guntinas-Lichius, Cesare Piazza, Gregory W. Randolph, Alessandra Rinaldo, Ohad Ronen, Maria E. Cabanillas, Ashok R. S
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • A Matched-Pair Analysis of Nuclear Morphologic Features Between Core Needle Biopsy and Surgical Specimen in Thyroid Tumors Using a Deep Learning Model
    Faridul Haq, Andrey Bychkov, Chan Kwon Jung
    Endocrine Pathology.2022; 33(4): 472.     CrossRef
  • Intraoperative Assessment of High-Risk Thyroid Nodules Based on Electrical Impedance Measurements: A Feasibility Study
    Jalil Beheshti Firoozabadi, Reihane Mahdavi, Khosro Shamsi, Hossein Ataee, Abdollah Shafiee, Hojat Ebrahiminik, Hossein Chegini, Parisa Hoseinpour, Afshin Moradi, Narges Yousefpour, Faeze Aghaei, Ali Fardoost, Alireza Ghelichli, Hadi Mokhtari Dowlatabad,
    Diagnostics.2022; 12(12): 2950.     CrossRef
  • Assessing the diagnostic performance of thyroid biopsy with recommendations for appropriate interpretation
    Su Min Ha, Jung Hwan Baek, Dong Gyu Na, Chan-Kwon Jung, Chong Hyun Suh, Young Kee Shong, Tae Yon Sung, Dong Eun Song, Jeong Hyun Lee
    Ultrasonography.2021; 40(2): 228.     CrossRef
  • Update on the Evaluation of Thyroid Nodules
    Victor J. Bernet, Ana-Maria Chindris
    Journal of Nuclear Medicine.2021; 62(Supplement): 13S.     CrossRef
  • Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature
    Maria Bellini, Marco Biffoni, Renato Patrone, Maria Borcea, Maria Costanzo, Tiziana Garritano, Rossella Melcarne, Rosa Menditto, Alessio Metere, Chiara Scorziello, Marco Summa, Luca Ventrone, Vito D’Andrea, Laura Giacomelli
    Journal of Clinical Medicine.2021; 10(22): 5258.     CrossRef
  • Laser Ablation Versus Radiofrequency Ablation for Benign Non-Functioning Thyroid Nodules: Six-Month Results of a Randomized, Parallel, Open-Label, Trial (LARA Trial)
    Roberto Cesareo, Claudio Maurizio Pacella, Valerio Pasqualini, Giuseppe Campagna, Mario Iozzino, Andrea Gallo, Angelo Lauria Pantano, Roberto Cianni, Claudio Pedone, Paolo Pozzilli, Chiara Taffon, Anna Crescenzi, Silvia Manfrini, Andrea Palermo
    Thyroid.2020; 30(6): 847.     CrossRef
  • 2019 Practice guidelines for thyroid core needle biopsy: a report of the Clinical Practice Guidelines Development Committee of the Korean Thyroid Association
    Chan Kwon Jung, Jung Hwan Baek, Dong Gyu Na, Young Lyun Oh, Ka Hee Yi, Ho-Cheol Kang
    Journal of Pathology and Translational Medicine.2020; 54(1): 64.     CrossRef
  • Morphological and Molecular Assessment in Thyroid Cytology Using Cell-Capturing Scaffolds
    Stefania Scarpino, Silvia Taccogna, Giuseppina Pepe, Enrico Papini, Martina D’Angelo, Federica Cascone, Daniele Nicoletti, Rinaldo Guglielmi, Andrea Palermo, Marcella Trombetta, Alberto Rainer, Chiara Taffon, Anna Crescenzi
    Hormone and Metabolic Research.2020; 52(11): 803.     CrossRef
  • European Thyroid Association Survey on Use of Minimally Invasive Techniques for Thyroid Nodules
    Laszlo Hegedüs, Andrea Frasoldati, Roberto Negro, Enrico Papini
    European Thyroid Journal.2020; 9(4): 194.     CrossRef
  • Malignancy risk of initially benign thyroid nodules: validation with various Thyroid Imaging Reporting and Data System guidelines
    Su Min Ha, Jung Hwan Baek, Young Jun Choi, Sae Rom Chung, Tae Yon Sung, Tae Yong Kim, Jeong Hyun Lee
    European Radiology.2019; 29(1): 133.     CrossRef
  • Tumor Volume Doubling Time in Active Surveillance of Papillary Thyroid Carcinoma
    Hye-Seon Oh, Hyemi Kwon, Eyun Song, Min Ji Jeon, Tae Yong Kim, Jeong Hyun Lee, Won Bae Kim, Young Kee Shong, Ki-Wook Chung, Jung Hwan Baek, Won Gu Kim
    Thyroid.2019; 29(5): 642.     CrossRef
  • Risk of Malignancy According to the Sub-classification of Atypia of Undetermined Significance and Suspicious Follicular Neoplasm Categories in Thyroid Core Needle Biopsies
    Sae Rom Chung, Jung Hwan Baek, Jeong Hyun Lee, Yu-Mi Lee, Tae-Yon Sung, Ki-Wook Chung, Suck Joon Hong, Min Ji Jeon, Tae Yong Kim, Young Kee Shong, Won Bae Kim, Won Gu Kim, Dong Eun Song
    Endocrine Pathology.2019; 30(2): 146.     CrossRef
  • Does Radiofrequency Ablation Induce Neoplastic Changes in Benign Thyroid Nodules: A Preliminary Study
    Su Min Ha, Jun Young Shin, Jung Hwan Baek, Dong Eun Song, Sae Rom Chung, Young Jun Choi, Jeong Hyun Lee
    Endocrinology and Metabolism.2019; 34(2): 169.     CrossRef
  • Response: Long-Term Outcomes Following Thermal Ablation of Benign Thyroid Nodules as an Alternative to Surgery: The Importance of Controlling Regrowth (Endocrinol Metab 2019;34:117–23, Jung Suk Sim et al.)
    Jung Suk Sim, Jung Hwan Baek
    Endocrinology and Metabolism.2019; 34(3): 325.     CrossRef
  • A Study on Head and Neck Malignant Lymphoma Diagnosed by Core Needle Biopsy
    Keisuke Yamamoto, Tsuyoshi Okuni, Makoto Kurose, Akira Yorozu, Kizuku Owada, Ryoto Yajima, Ayumi Takahashi, Kazufumi Obata, Atsushi Kondo, Kenichi Takano
    Practica Oto-Rhino-Laryngologica.2019; 112(9): 609.     CrossRef
  • The Role of Core Needle Biopsy for the Evaluation of Thyroid Nodules with Suspicious Ultrasound Features
    Sae Rom Chung, Jung Hwan Baek, Young Jun Choi, Tae-Yon Sung, Dong Eun Song, Tae Yong Kim, Jeong Hyun Lee
    Korean Journal of Radiology.2019; 20(1): 158.     CrossRef
  • Safety and Efficacy of Radiofrequency Ablation for Nonfunctioning Benign Thyroid Nodules in Children and Adolescents in 14 Patients over a 10-Year Period
    Min Ji Hong, Jin Yong Sung, Jung Hwan Baek, Mi Su Je, Dong Whan Choi, Hyunju Yoo, Sae Jeong Yang, Sang Yu Nam, Eun Young Yoo
    Journal of Vascular and Interventional Radiology.2019; 30(6): 900.     CrossRef
  • Reliability of core needle biopsy as a second-line procedure in thyroid nodules with an indeterminate fine-needle aspiration report: a systematic review and meta-analysis
    Pierpaolo Trimboli, Luca Giovanella
    Ultrasonography.2018; 37(2): 121.     CrossRef
  • The Significance of Having an Excellent Patient's Comfort with Thyroid Core Needle Biopsy
    Pierpaolo Trimboli, Luca Giovanella
    Endocrinology and Metabolism.2018; 33(1): 53.     CrossRef
  • Ultrasonographic Echogenicity and Histopathologic Correlation of Thyroid Nodules in Core Needle Biopsy Specimens
    Ji-hoon Kim, Dong Gyu Na, Hunkyung Lee
    Korean Journal of Radiology.2018; 19(4): 673.     CrossRef
  • A Comparison of Ultrasound-Guided Fine Needle Aspiration versus Core Needle Biopsy for Thyroid Nodules: Pain, Tolerability, and Complications
    Eun Ji Jeong, Sae Rom Chung, Jung Hwan Baek, Young Jun Choi, Jae Kyun Kim, Jeong Hyun Lee
    Endocrinology and Metabolism.2018; 33(1): 114.     CrossRef
Close layer
Revised Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Thyroid Cancer.
Ka Hee Yi, Young Joo Park, Sung Soo Koong, Jung Han Kim, Dong Gyu Na, Jin Sook Ryu, So Yeon Park, In Ae Park, Chung Hwan Baek, Young Kee Shong, Young Don Lee, Jaetae Lee, Jeong Hyun Lee, Jae Hoon Chung, Chan Kwon Jung, Seung Ho Choi, Bo Youn Cho
Endocrinol Metab. 2010;25(4):270-297.   Published online December 1, 2010
DOI: https://doi.org/10.3803/EnM.2010.25.4.270
  • 3,769 View
  • 45 Download
  • 36 Crossref
AbstractAbstract PDF
No abstract available.

Citations

Citations to this article as recorded by  
  • Thyroid Cancer Incidence Among Korean Individuals: A Comparison of South Korea and the United States
    Dohun Kim, Guan Li, Peter K. Moon, Yifei Ma, Soohyun Sim, Sung Y. Park, Minkyung Oh, Uchechukwu C. Megwalu
    The Laryngoscope.2024; 134(9): 4156.     CrossRef
  • Imaging Recommendations for Diagnosis, Staging, and Management of Cancer of the Thyroid, Parathyroid, and Salivary Glands
    Abhishek Mahajan, Shreya Shukla, Suman Kumar Ankathi, Anuradha Shukla, Richa Vaish, Shubham Suryavanshi, Ujjwal Agarwal, Vasundhara Patil, Arpita Sahu, Shubham Padashetty, Sarbani Ghosh Laskar, Vijay Patil, Vanita Noronha, Nandini Menon, Kumar Prabhash, A
    Indian Journal of Medical and Paediatric Oncology.2023; 44(02): 159.     CrossRef
  • Authors’ Reply: A Time Trend Analysis of 5000 Robotic Thyroidectomies via Bilateral Axillo‐Breast Approach
    JungHak Kwak, Hyeong Won Yu, Jong‐hyuk Ahn, Su‐jin Kim, Young Jun Chai, June Young Choi, Kyu Eun Lee
    World Journal of Surgery.2023; 47(8): 2086.     CrossRef
  • 2023 Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules
    Young Joo Park, Eun Kyung Lee, Young Shin Song, Soo Hwan Kang, Bon Seok Koo, Sun Wook Kim, Dong Gyu Na, Seung-Kuk Baek, So Won Oh, Min Kyoung Lee, Sang-Woo Lee, Young Ah Lee, Yong Sang Lee, Ji Ye Lee, Dong-Jun Lim, Leehi Joo, Yuh-Seog Jung, Chan Kwon Jung
    International Journal of Thyroidology.2023; 16(1): 1.     CrossRef
  • Optimization of the design parameters for a thyroid care nuclide monitoring diverging collimator using Monte Carlo simulation
    Dong-Hee Han, Seung-Jae Lee, Jang-Oh Kim, Da-Eun Kwon, Kyung-Hwan Jung, Cheol-Ha Baek
    Journal of the Korean Physical Society.2022; 81(7): 675.     CrossRef
  • Active Surveillance for Papillary Thyroid Microcarcinoma in a Population with Restrictive Diagnostic Workup Strategies
    Ivona Lončar, Sam P.J. van Dijk, Madelon J.H. Metman, Jia Feng Lin, Schelto Kruijff, Robin P. Peeters, Anton F. Engelsman, Tessa M. van Ginhoven
    Thyroid.2021; 31(8): 1219.     CrossRef
  • Decreasing trends in thyroid cancer incidence in South Korea: What happened in South Korea?
    Chang‐Mo Oh, Jiwon Lim, Yuh Seog Jung, Yeol Kim, Kyu‐Won Jung, Seri Hong, Young‐Joo Won
    Cancer Medicine.2021; 10(12): 4087.     CrossRef
  • Efficacy of Differential Diagnosis of Thyroid Nodules by Shear Wave Elastography—the Stiffness Map
    Myung Hi Yoo, Hye Jeong Kim, In Ho Choi, Suyeon Park, Sumi Yun, Hyeong Kyu Park, Dong Won Byun, Kyoil Suh
    Journal of the Endocrine Society.2021;[Epub]     CrossRef
  • Spatial distribution and determinants of thyroid cancer incidence from 1999 to 2013 in Korea
    Jieun Jang, Dae-Sung Yoo, Byung Chul Chun
    Scientific Reports.2021;[Epub]     CrossRef
  • Income differences in screening, incidence, postoperative complications, and mortality of thyroid cancer in South Korea: a national population-based time trend study
    Hee-Yeon Kang, Ikhan Kim, Yeon-Yong Kim, Jinwook Bahk, Young-Ho Khang
    BMC Cancer.2020;[Epub]     CrossRef
  • Differential Diagnosis of Thyroid Follicular Neoplasm from Nodular Hyperplasia by Shear Wave Elastography
    Myung Hi Yoo, Hye Jeong Kim, In Ho Choi, Ji-Oh Mok, Hyeong Kyu Park, Dong Won Byun, Kyoil Suh
    Soonchunhyang Medical Science.2019; 25(1): 10.     CrossRef
  • Diagnostic Performance of Shear Wave Elastography as Add-on Test in Thyroid Nodules: a Systematic Review and Meta-Analysis
    Sun-young Park, Ji Yang Song, Min Jin Lee, Kyung Min Lee, Mi Hye Jeon, Ryeo Jin Ko, Seok-Hyun Kim, Bong Joo Kang
    International Journal of Thyroidology.2018; 11(1): 31.     CrossRef
  • Structural Equation Modeling on Health-related Quality of Life among Patients with Thyroid Cancer
    Seon Young Lee, Hyun Kyung Kim
    Korean Journal of Adult Nursing.2018; 30(2): 171.     CrossRef
  • Prevalence and Annual Incidence of Thyroid Disease in Korea from 2006 to 2015: A Nationwide Population-Based Cohort Study
    Hyemi Kwon, Jin-hyung Jung, Kyung-Do Han, Yong-Gyu Park, Jung-Hwan Cho, Da Young Lee, Ji Min Han, Se Eun Park, Eun-Jung Rhee, Won-Young Lee
    Endocrinology and Metabolism.2018; 33(2): 260.     CrossRef
  • Ten Years of the Korean Thyroid Association: Achievement and Future
    Young Joo Park, Young Shin Song, Ka Hee Yi
    International Journal of Thyroidology.2018; 11(1): 1.     CrossRef
  • Prediction of Contralateral Occult Malignant Nodule in Patients with Unilaterally Confined Papillary Thyroid Carcinomas
    Sang Wook Jo, Ha Kyoung Park, Tae Kwun Ha
    Journal of Endocrine Surgery.2018; 18(3): 191.     CrossRef
  • Surgical Treatment Guidelines for Patients with Differentiated Thyroid Cancer: The Korean Association of Thyroid and Endocrine Surgeons (KATES) Guidelines Taskforce
    Jin-Woo Park, Ki-Wook Chung, Ji-Sup Yun, Hyungju Kwon, Hoon Yub Kim, Kee Hyun Nam, Kyoung Sik Park, Min Ho Park, Ja Sung Bae, Hyun Jo Youn, Kyu Eun Lee, Chi Young Lim, Jin Hyang Jung, Jun-Ho Choe, Lee Su Kim, Su Jung Lee, Jung Han Yoon
    Korean Journal of Endocrine Surgery.2017; 17(1): 1.     CrossRef
  • Thyroid fine-needle aspiration biopsy positively correlates with increased diagnosis of thyroid cancer in South Korean patients
    Yoon Jae Cho, Do Young Kim, Eun-Cheol Park, Kyu-Tae Han
    BMC Cancer.2017;[Epub]     CrossRef
  • Current trends of practical issues concerning micropapillary thyroid carcinoma
    Yoon Se Lee, Byung-Joo Lee, Hyun Joon Hong, Kang-Dae Lee
    Medicine.2017; 96(45): e8596.     CrossRef
  • The Use of the Bethesda System for Reporting Thyroid Cytopathology in Korea: A Nationwide Multicenter Survey by the Korean Society of Endocrine Pathologists
    Mimi Kim, Hyo Jin Park, Hye Sook Min, Hyeong Ju Kwon, Chan Kwon Jung, Seoung Wan Chae, Hyun Ju Yoo, Yoo Duk Choi, Mi Ja Lee, Jeong Ja Kwak, Dong Eun Song, Dong Hoon Kim, Hye Kyung Lee, Ji Yeon Kim, Sook Hee Hong, Jang Sihn Sohn, Hyun Seung Lee, So Yeon Pa
    Journal of Pathology and Translational Medicine.2017; 51(4): 410.     CrossRef
  • Does the Risk of Metabolic Syndrome Increase in Thyroid Cancer Survivors?
    Min-Hee Kim, Jin-young Huh, Dong-jun Lim, Moo-Il Kang
    Thyroid.2017; 27(7): 936.     CrossRef
  • Surgical Treatment Guidelines for Patients with Differentiated Thyroid Cancer: The Korean Association of Thyroid and Endocrine Surgeons (KATES) Guidelines Taskforce
    Jin-Woo Park, Ki-Wook Chung, Ji-Sup Yun, Hyungju Kwon, Hoon Yub Kim, Kee Hyun Nam, Kyoung Sik Park, Min Ho Park, Ja Sung Bae, Hyun Jo Youn, Kyu Eun Lee, Chi Young Lim, Jin Hyang Jung, Jun-Ho Choe, Lee Su Kim, Su Jung Lee, Jung Han Yoon
    Korean Journal of Endocrine Surgery.2017; 17(1): 1.     CrossRef
  • Incidental Detection of Struma Ovarii on the Whole Body Scan in a Differentiated Thyroid Cancer Patient
    Hye-Seon Oh, Eyun Song, Dong Eun Song, Won Bae Kim
    International Journal of Thyroidology.2016; 9(2): 180.     CrossRef
  • The Experience of Receiving Radioactive Iodine Therapy among Thyroid Cancer Patients
    Kyung Ok Kang, Hyun Kyung Kim, Ji Young Kim, Seok Tae Lim
    Journal of East-West Nursing Research.2016; 22(2): 148.     CrossRef
  • Comparison of two- and three-dimensional sonography for the prediction of the extrathyroidal extension of papillary thyroid carcinomas
    Yang Seon Yi, Sang Soo Kim, Won Jin Kim, Min Jung Bae, Ji Hyun Kang, Bo Gwang Choi, Yun Kyung Jeon, Bo Hyun Kim, Byung Joo Lee, Soo Geun Wang, In Joo Kim, Yong Ki Kim
    The Korean Journal of Internal Medicine.2016; 31(2): 313.     CrossRef
  • Changing trends in the management of well-differentiated thyroid carcinoma in Korea
    Yong Sang Lee, Hang-Seok Chang, Cheong Soo Park
    Endocrine Journal.2016; 63(6): 515.     CrossRef
  • Low Dose versus High Dose Radioiodine Therapy
    Kyoung Sook Won
    Journal of Korean Thyroid Association.2015; 8(1): 14.     CrossRef
  • History of Korean Thyroid Association and Recent Debates on Diagnosis and Treatment of Thyroid Cancer in Korea
    Kwang Woo Lee
    Journal of Korean Thyroid Association.2015; 8(1): 36.     CrossRef
  • Lowered cutoff of lymph node fine-needle aspiration thyroglobulin in thyroid cancer patients with serum anti-thyroglobulin antibody
    Kwanhoon Jo, Min-Hee Kim, Yejee Lim, So-Lyung Jung, Ja-Seong Bae, Chan-Kwon Jung, Moo-Il Kang, Bong-Yun Cha, Dong-Jun Lim
    European Journal of Endocrinology.2015; 173(4): 489.     CrossRef
  • Time Trends Analysis of Characteristics of Patients with Thyroid Cancer in a Single Medical Center
    Hyung Seo Jung, Min Ji Jeon, Dong Eun Song, Suck Joon Hong, Won Gu Kim, Tae Yong Kim, Young Kee Shong, Won Bae Kim
    Journal of Korean Thyroid Association.2014; 7(2): 159.     CrossRef
  • Unfounded Reports on Thyroid Cancer
    Jae Hoon Chung
    Journal of Korean Medical Science.2014; 29(8): 1033.     CrossRef
  • Regional Lymph Node Metastasis in Papillary Thyroid Cancer
    Jae Hyun Park, Kang San Lee, Keum-Seok Bae, Seong Joon Kang
    Journal of Korean Thyroid Association.2014; 7(2): 129.     CrossRef
  • Methods and Clinical Efficacy of Dosimetry-Based Treatment in Radioiodine Therapy of Thyroid Cancer
    Jin Chul Paeng, June-Key Chung
    Journal of Korean Thyroid Association.2013; 6(1): 43.     CrossRef
  • Two Cases of Non-Small Cell Lung Cancer Masquerading as Metastatic Papillary Thyroid Cancer
    Ju Hee Lee, Se-Hoon Lee, Hye Sook Min, Ji-hoon Kim, Do Joon Park, Young Joo Park
    Journal of Korean Thyroid Association.2012; 5(2): 157.     CrossRef
  • Diagnostic Dilemma of a Follicular Lesions/Neoplasm in Thyroid Fine Needle Aspiration Cytology
    Chan Kwon Jung
    Journal of Korean Thyroid Association.2012; 5(2): 104.     CrossRef
  • Updated guidelines for the diagnosis and management of thyroid nodules
    Ka Hee Yi
    Journal of the Korean Medical Association.2011; 54(6): 629.     CrossRef
Close layer
A Patient with Concurrent Medullary and Papillary Carcinoma of the Thyroid.
Seung Hee Yoo, Keun Joon Lim, Seung Hwan Lee, Ji Hyun Kim, Soon Hwa Hong, Jae Hyoung Cho, Chan Kwon Jung, Hyuk Sang Kwon, Kun Ho Yoon, Min Sik Kim, Bong Yun Cha, Ho Young Son
J Korean Endocr Soc. 2007;22(3):235-240.   Published online June 1, 2007
DOI: https://doi.org/10.3803/jkes.2007.22.3.235
  • 2,064 View
  • 19 Download
  • 1 Crossref
AbstractAbstract PDF
The origin of medullary thyroid carcinoma and papillary thyroid carcinoma are embryogenically different, so these tumors have been thought to be independent of each other. We experienced a case of concurrent medullary and papillary thyroid carcinoma in one patient. The patient underwent total thyroidectomy and both two tumors were located at different lobes, respectively. Both tumors showed their own characteristic pathologic and immunohistochemical findings. The patient's elevated calcitonin level returned to the normal range after operation and there has been no evidence of recurrence. It is still controversial whether the concurrency is just coincidental or it arises from activation of a common tumorigenic pathway.

Citations

Citations to this article as recorded by  
  • A Case of Concurrent Papillary and Medullary Thyroid Carcinomas Detected as Recurrent Medullary Carcinoma after Initial Surgery for Papillary Carcinoma
    Dongbin Ahn, Jin Ho Sohn, Ji Young Park
    Journal of Korean Thyroid Association.2013; 6(1): 80.     CrossRef
Close layer

Endocrinol Metab : Endocrinology and Metabolism
TOP