Warning: fopen(/home/virtual/enm-kes/journal/upload/ip_log/ip_log_2024-04.txt): failed to open stream: Permission denied in /home/virtual/lib/view_data.php on line 88 Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 89 Two Cases of Acromegaly with Empty Sella.
Skip Navigation
Skip to contents

Endocrinol Metab : Endocrinology and Metabolism

clarivate
OPEN ACCESS
SEARCH
Search
Advanced Search
mobile menu button

Articles

Page Path
HOME > Endocrinol Metab > Volume 21(6); 2006 > Article
Case Report Two Cases of Acromegaly with Empty Sella.
Hyun Sun Cho, Tae Seo Sohn, So Young Lee, Kyoung Hee Kim, Yu Kyung Park, Jung Min Lee, Hyun Shik Son
Endocrinology and Metabolism 2006;21(6):572-576
DOI: https://doi.org/10.3803/jkes.2006.21.6.572
Published online: December 1, 2006
  • 1,556 Views
  • 28 Download
  • 0 Crossref
  • 0 Scopus
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Korea.
Full Article

Download PDF Download PDF

Abstract

An empty sella may develop as a consequence of a primary congenital weakness of the diaphragm for which no secondary cause is evident. A secondary empty sella may develop after infarction of a pituitary adenoma or because of surgical or radiation-induced damage to the sellar diaphragm. Acromegaly is caused by growth hormone (GH) hypersecretion and the resultant elevated levels of circulating insulin like growth factor-1. The underlying abnormality in more than 98% of cases is hypersecretion of GH by a pituitary GH-producing tumor. Necrosis and hemorrhage, which frequently occur in pituitary adenomas, may lead to complete or partial disappearance of the adenoma, and subsequently, to an empty sella. We report two cases of acromegaly with empty sella, and the patients had no symptoms of pituitary apoplexy.

Related articles
Endocrinol Metab : Endocrinology and Metabolism
© Korean Endocrine Society.