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HOME > Endocrinol Metab > Volume 20(5); 2005 > Article
Case Report A case of Methimazole-Induced Cholestatic Jaundice With Agranulocytosis.
Sang Gu Kang, Jong Oh Bae, Eun Young Lee, Seong Min Lim, Sang Kun Cho, Ji Hye Kim, Sun Kyung Song
Endocrinology and Metabolism 2005;20(5):519-523
DOI: https://doi.org/10.3803/jkes.2005.20.5.519
Published online: October 1, 2005
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Division of Endocrinology and Metabolism, Department of Internal Medicine, Presbyterian Medical Center, Cheonju, Korea.
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Abstract

Methimazole is a widely used and generally well-tolerated antithyroid agent. Adverse reactions occur in 1~5% of patients taking methimazole medication, but these are most commonly transient, benign leukopenia and a skin rash. Severe cholestatic jaundice, combined with agranulocytosis, has been known as a rare complication. Herein, a case of methimazole induced cholestatic jaundice, with agranulocytosis, is reported.

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