Table 1Anthropometric and Laboratory Characteristics
Variable |
Value |
No. of cases |
124 |
Age, yr |
59.9±7.1 |
No. of years since menopause |
9.1±7.6 |
BMI, kg/m2
|
24.2±3.4 |
SBP, mm Hg |
123.9±16.0 |
DBP, mm Hg |
75.8±10.5 |
Pref-1, ng/mL |
0.28±0.10 |
T-score |
|
Lumbar spine |
−0.97±1.25 |
Femur neck |
−0.82±0.89 |
Total hip |
−0.40±1.04 |
BMD, g/cm2
|
|
Spine |
0.993±0.150 |
Femur neck |
0.802±0.107 |
Total hip |
0.886±0.124 |
Fracture history |
|
Whole area |
23/121 (19) |
Spine |
2/122 (1.6) |
Hip |
0/122 (0) |
Calcium, mg/dL |
9.5±0.3 |
Phosphorous, mg/dL |
3.8±0.5 |
Albumin, mg/dL |
4.3±0.3 |
Creatinine, mg/dL |
0.6±0.1 |
Osteocalcin, ng/mL |
12.6±2.7 |
C-telopeptide, ng/mL |
0.8±0.4 |
25(OH) vitamin D3, ng/mL |
6.1±3.3 |
Table 2Adjusted Associations between Serum Preadipocyte Factor 1 Levels and Bone Mineral Densities
Variable |
β |
R2
|
P value |
Lumbar spine |
0.109 |
0.038 |
0.109 |
Femur neck |
0.018 |
0.017 |
0.869 |
Total hip |
0.155 |
0.041 |
0.090 |
Table 3Bone Mineral Densities and Preadipocyte Factor 1 Levels according to a History of Fracture
Variable |
No fracture history |
Fracture history |
P value |
No. of cases |
98 |
23 |
|
Age, yr |
59.2±0.7 |
63.2±1.6 |
0.016 |
BMI, kg/m2
|
24.1±0.4 |
24.1±0.7 |
0.943 |
T-score |
|
|
|
Lumbar spine |
–0.90±1.20 |
–1.52±–2.01 |
0.025 |
Femur neck |
–0.72±0.87 |
–1.36±0.68 |
0.001 |
Total hip |
–0.31±0.93 |
–1.00±0.92 |
0.002 |
BMD, g/cm2
|
|
|
|
Spine |
1.000±0.015 |
0.927±0.029 |
0.025 |
Femur neck |
0.813±0.011 |
0.736±0.017 |
0.001 |
Total hip |
0.897±0.011 |
0.815±0.023 |
0.002 |
Pref-1, ng/mL |
0.252±0.010 |
0.282±0.023 |
0.212 |
Calcium, mg/dL |
9.53±0.03 |
9.50±0.06 |
0.606 |
Phosphorous, mg/dL |
3.86±0.05 |
3.73±0.10 |
0.253 |
Albumin, mg/dL |
4.28±0.03 |
4.22±0.04 |
0.205 |
Creatinine, mg/dL |
0.64±0.01 |
0.66±0.03 |
0.544 |
Osteocalcin, ng/mL |
12.60±0.28 |
12.35±0.56 |
0.693 |
C-telopeptide, ng/mL |
0.77±0.04 |
0.83±0.07 |
0.461 |
25(OH) vitamin D3, ng/mL |
5.91±0.31 |
6.55±0.83 |
0.479 |
Table 4Adjusted Correlations between Preadipocyte Factor 1 Levels and Bone Mineral Densities according to a History of Fracture
Variable |
Absence of fracture history |
Presence of fracture history |
β |
R2
|
P value |
β |
R2
|
P value |
Lumbar spine |
0.144 |
0.129 |
0.290 |
0.296 |
0.498 |
0.187 |
Femur neck |
0.015 |
0.296 |
0.869 |
–0.086 |
0.365 |
0.558 |
Total hip |
0.172 |
0.264 |
0.079 |
–0.061 |
0.653 |
0.681 |