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Case Report Langerhans Cell Histiocytosis in the Thyroid and Draining Lymph Nodes: A Case Report.
Dong Hae Chung, Seung Yeon Ha, Hyun Yee Cho, Na Rae Kim, Jung Suk An, Young Don Lee, Sanghui Park
Endocrinology and Metabolism 2012;27(2):138-141
DOI: https://doi.org/10.3803/EnM.2012.27.2.138
Published online: June 20, 2012
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1Department of Pathology, Gachon University School of Medicine, Incheon, Korea.
2Department of Surgery, Gachon University School of Medicine, Incheon, Korea.
3Department of Pathology, Ewha Womans University School of Medicine, Seoul, Korea. spark0430@ewha.ac.kr

A 53-year-old woman was presented with several 0.3-0.6 cm-sized nodules within the right lobe of the thyroid. Histologic sections of the thyroid demonstrated multiple papillary microcarcinomas in the background of lymphocytic thyroiditis, with a small focus of Langerhans cell histiocytosis (LCH). Small LCH nodules were also found in the draining cervical lymph nodes. Although the association of LCH with papillary thyroid carcinoma in the thyroid has been reported, their co-existence with LCH in the draining lymph nodes is very rare.

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